ライフサイエンスコーパス: aetiology

1 n pattern among patients with embolic stroke aetiology.

2 , as well as mutational processes of unknown aetiology.

3 d PPIL3 at 2q33 in ER-negative breast cancer aetiology.

4 lar mechanisms underlying its multifactorial aetiology.

5 to the molecular-level understanding of its aetiology.

6 n to play an important role in breast cancer aetiology.

7 uencies differed significantly with dystonia aetiology.

8 yet there is little consensus regarding its aetiology.

9 atocytosis and non-immune hydrops of unknown aetiology.

10 s whether MBS has a genetic or a non-genetic aetiology.

11 efined by signs and symptoms, rather than by aetiology.

12 pared with breast cancer without a radiation aetiology.

13 associations might be due to shared genetic aetiology.

14 common genetic variants involved in disease aetiology.

15 alities can be downstream of a glutamatergic aetiology.

16 argely driven by those with a known epilepsy aetiology.

17 n parents and siblings, to shed new light on aetiology.

18 ; 95% CI 0.8 to 2.8 in subjects with unknown aetiology.

19 uman seizures of both genetic and autoimmune aetiology.

20 enia and cannabis is due to a shared genetic aetiology.

21 after exclusion of those with a progressive aetiology.

22 pects of genetic architecture and biological aetiology.

23 onstrated which points to an immune-mediated aetiology.

24 now considered as an important factor in AD aetiology.

25 6 HCC arising in liver disorders with varied aetiology.

26 ncident cases followed by 30% with uncertain aetiology.

27 early 50% of FALS cases have unknown genetic aetiology.

28 s and commentaries relating to human disease aetiology.

29 in unknown, but may reflect a shared genetic aetiology.

30 is a key factor in mood and anxiety disorder aetiology.

31 eatment; few studies have yet to explore its aetiology.

32 ortant clues for future research into asthma aetiology.

33 tigations were in favour of a post-traumatic aetiology.

34 een suggested that there is an immunological aetiology.

35 -8-unrelated PEL-like lymphomas with unknown aetiology.

36 he limited understanding of its multifaceted aetiology.

37 critical role of the CDKN2 locus in BCP-ALL aetiology.

38 read, suggesting the possibility of distinct aetiologies.

39 n is ascribed to perinatal asphyxia or other aetiologies.

40 havioural syndrome produced by these diverse aetiologies.

41 ly among the different syndromes and genetic aetiologies.

42 a to discriminate CLIPPERS from non-CLIPPERS aetiologies.

43 g hundreds of traits for overlapping genetic aetiologies.

44 t, or are distinct behaviours with different aetiologies.

45 actors, and infrequently caused by infective aetiology (112/1207 (9.2%)) such as Clostridium difficil

46 (48 and 32 respectively) and gastric varices aetiologies (2.8) when compared with other bleeds; non-u

47 antly increased in those with a known remote aetiology (2.5; 95% CI (1.4 to 3.8)).

48 Despite different aetiologies, age-related macular degeneration and most i

49 s their utility for detecting shared genetic aetiology among traits has become appreciated; PRS can a

50 izures might have different patient-specific aetiologies and electrographic signatures, our model sug

51 man RTT severity, reveals compound molecular aetiologies and provides a valuable resource in the sear

52 o 4.6 in subjects with remote or progressive aetiology and 1.7; 95% CI 0.8 to 2.8 in subjects with un

53 an genetics, which are to understand disease aetiology and aid in disease screening, diagnosis, progn

54 on available information regarding microbial aetiology and antimicrobial susceptibility, but sub-Saha

55 ny epileptic encephalopathies have a genetic aetiology and are often associated with de novo mutation

56 arre syndrome, as many will have a metabolic aetiology and be potentially treatable.

57 atients, and its relationship with infective aetiology and clinical outcomes.

58 (MODY), we sequenced MODY cases with unknown aetiology and compared variant frequencies to large publ

59 cancer is important for understanding cancer aetiology and designing preventive measures.

60 nction in skeletal muscle contributes to the aetiology and development of muscle diseases and metabol

61 esses of human GWAS in understanding disease aetiology and identifying potential drug targets, microb

62 ion is critically important when considering aetiology and management.

63 The aetiology and mechanisms underlying most cases of human

64 Advancements in knowledge of obesity aetiology and mobile phone technology have created the o

65 However, many aspects of its aetiology and molecular mechanisms remain unknown.

66 BP) is a common debilitating condition which aetiology and pathogenesis are poorly understood.

67 ises to provide renewed understanding of the aetiology and pathogenesis of age related neurodegenerat

68 rections for future studies to delineate the aetiology and pathogenesis of bipolar disorder, indicate

69 The aetiology and pathogenesis of non-genetic forms of front

70 patterns differ significantly with dystonia aetiology and phenotype.

71 ric Multicenter Study (GEMS) to identify the aetiology and population-based burden of paediatric diar

72 offer unique opportunities to understand the aetiology and possible treatment of synovial joint disea

73 In this review, we summarise the anatomy, aetiology and presentation of posterior circulation stro

74 pertension need not necessarily have a renal aetiology and that long-term arterial pressure could be

75 r varies greatly depending on the underlying aetiology and the range of possible differential diagnos

76 These findings may be relevant to the aetiology and treatment of diverse neurological and psyc

77 ds light on mutational processes and disease aetiology, and in mutation frequency across the genome,

78 Many studies on the epidemiology, aetiology, and management of epilepsy in sub-Saharan Afr

79 burden, few data are available on incidence, aetiology, and outcomes, particularly regarding impairme

80 atients with a known or later proven genetic aetiology, and subsequently felt to be part of the pheno

81 the factor structure of spatial anxiety, its aetiology, and the origins of its association with gener

82 ogy; (iii) suspected non-Alzheimer's disease aetiology; and (iv) healthy ageing.

83 prognosis; however, its cellular origins and aetiology are poorly understood.

84 ce for further investigation of its specific aetiology as it relates to human psoriasis.

85 inking how best to undertake research on the aetiology, assessment, and treatment of these disorders,

86 c profile scoring to test for shared genetic aetiology between cognitive functions and neuropsychiatr

87 nalyses were used to test for shared genetic aetiology between tiredness and up to 29 physical and me

88 alysis indicated considerable shared genetic aetiology between trail making, general cognitive functi

89 acute pancreatitis overall and for gallstone aetiology but not for alcoholic acute pancreatitis, alth

90 ontaminants have been implicated in asthma's aetiology but their effect on lung function is not well

91 is a sporadic disorder with multiple likely aetiologies, but frequently considered to be caused by b

92 acute pancreatitis overall or for gallstone aetiology, but for alcoholic acute pancreatitis, mortali

93 NFSF10 gene may be involved in breast cancer aetiology, but further functional experiments are needed

94 ome and are differentiated from non-CLIPPERS aetiologies by neuroradiological and neuropathological f

95 highly heritable complex disorder of unknown aetiology characterized by hyperandrogenism, chronic ano

96 This study outlines the aetiology, clinical presentation, and treatment outcomes

97 upper GI bleeding and its relationship with aetiology, co-morbidities and socio-demographic factors.

98 rtality rate to construct the Bronchiectasis Aetiology Comorbidity Index (BACI).

99 ement guideline are clinical classification, aetiology, diagnosis, investigations, treatment guidance

100 Melanocytes have an apparently simple aetiology, differentiating from the neural crest and mig

101 s always been technology-driven, rather than aetiology-driven; as new techniques have appeared, clini

102 Here, we identify the aetiology driving AI in mice carrying a p.S55I mutation

103 oposed prognostic factors including dystonia aetiology, dystonia phenotype, age at onset of dystonia,

104 has been discussed in the context of disease aetiology, especially cancer.

105 Identifying a common aetiology for AI resulting from mutations in two differe

106 findings demonstrate a common shared genetic aetiology for CHD and renal anomalies, indicating that C

107 ation analyses indicate causal roles in PCOS aetiology for higher BMI (P=2.5 x 10(-9)), higher insuli

108 the E410K substitution defines a new genetic aetiology for Moebius syndrome, Kallmann syndrome and cy

109 that could provide insight into the disease aetiology for the cardiac phenotype in many laminopathie

110 (r = 0.78, P < 0.00005), indicating a shared aetiology for these seemingly unrelated abnormalities.

111 support the hypothesis of an immune-mediated aetiology for this canine myopathy and give credibility

112 This approach to cancer aetiology has also incriminated various endogenous, enzy

113 imited understanding of their neurocognitive aetiology has hampered progress towards effective treatm

114 th issue, an incomplete understanding of its aetiology has hindered our ability to treat this complex

115 admission rates for encephalitis of unknown aetiology have increased by 37% since the introduction o

116 Admissions with a specified viral aetiology have increased since 2000.

117 hotic or dysplastic nodules and 79% of mixed-aetiology HCC.

118 (ii) mixed Alzheimer's disease and vascular aetiology; (iii) suspected non-Alzheimer's disease aetio

119 fy genetic correlations that indicate shared aetiologies in both sexes between puberty timing and bod

120 ears and admission rate trends for specified aetiologies in relation to introduction of PCR testing a

121 educed fetoplacental blood flow are putative aetiologies in the pathogenesis of fetal growth restrict

122 ty was increased significantly for alcoholic aetiology in August 2004, the official month that the fi

123 arcinoma (HCC) but the role of liver disease aetiology in cancer development remains under-explored.

124 nemia, we were able to determine the genetic aetiology in eight patients and delineate the clinical a

125 especially in ischaemic injury-the commonest aetiology in lesion-deficit studies-where the anatomy is

126 However, the aetiology in many individuals with these cortical malfor

127 t of intracranial vessels is the predominant aetiology in most Asian countries.

128 pt earlier serological tests to identify the aetiology in similar cases.

129 much clearer picture of infantile nystagmus aetiology in the future.

130 ew) and problems related to pathogenesis and aetiology (in the companion Personal View).

131 r viral meningitis, including specific viral aetiologies, in children younger than 15 years.

132 Aetiology included 59% IgE-mediated anaphylaxis, 2% non-

133 phenotypes, due to uncertainty about disease aetiology, inconclusive results in early psychiatric gen

134 NL4) is a strong predictor of fibrosis in an aetiology-independent manner.

135 gs establish rs12979860 genotype as a strong aetiology-independent predictor of tissue inflammation a

136 We hypothesize that in some patients the aetiology involves genetic mutations that result in a de

137 f end-stage renal disease, but their genetic aetiology is not well understood.

138 s and publications over the past decade, the aetiology is still unknown.

139 The commonest aetiology is stroke.

140 eeding with subarachnoid haemorrhage with no aetiology is uncommon.

141 believed to be an acquired disorder, but its aetiology is unknown.

142 ion), but whether they have a shared genetic aetiology is unknown.

143 hought to have a significant role in disease aetiology is Zn(2+) homeostasis, which is disrupted in t

144 Among the precipitating aetiologies, ischaemic disease is a leading cause of hea

145 f the clinical syndrome of pneumonia and its aetiologies, its accurate diagnosis is challenging when

146 75 (6.58-13), not significantly differing by aetiology (Kruskal-Wallis test p>0.05); dystonia-onset a

147 ite a clear heritable component, the genetic aetiology leading to non-syndromic MVP has remained elus

148 wly described human prion disease of unknown aetiology lying out with the hitherto recognized phenoty

149 ur in MS and describe the clinical symptoms, aetiology, neuroimaging findings and management strategi

150 l changes and mutation signatures of unknown aetiology, not previously identified in melanoma.

151 Aetiologies of camptocormia are heterogeneous, and Parki

152 dented opportunities to identify the genetic aetiologies of hitherto molecularly uncharacterised cond

153 zoonotic transmission and adds to the known aetiologies of infectious diseases for this region.

154 combined study of genetic and environmental aetiologies of severe mental disorders.

155 Both vascular and neurological aetiologies of this pain have been suggested but remain

156 Here we investigated the aetiology of 'anabolic resistance' in older humans.

157 Our study includes molecules related to the aetiology of 934 health-threatening conditions and used

158 ET-1), a mitogenic peptide implicated in the aetiology of a number of diseases, including cancer.

159 omaviruses (HPVs) has been implicated in the aetiology of a variety of cancers.

160 inflammatory processes are important in the aetiology of AD, we have now analysed the correlation of

161 logical processes of likely relevance to the aetiology of ADHD.

162 cohol misuse, these models shed light on the aetiology of alcohol misuse and suggest targets for prev

163 zed that these PUFAs may be important in the aetiology of allergic diseases.

164 Despite much research into the aetiology of allergies, little progress has been made in

165 esults increase our understanding of genetic aetiology of ALS.Amyotrophic lateral sclerosis (ALS) is

166 The aetiology of Alzheimer's disease (AD) is believed to inv

167 Abeta(42)) in the brain is implicated in the aetiology of Alzheimer's disease (AD).

168 oping auditory cortex that may relate to the aetiology of amblyaudia, a binaural hearing impairment a

169 and high-density lipoprotein pathways in the aetiology of AMD.

170 the relative contribution of malaria to the aetiology of anaemia in this setting.

171 enetic risk factor, although its role in the aetiology of AS remains elusive.

172 Although the aetiology of ASD has a strong genetic component, there i

173 manifestations and complex, largely genetic aetiology of ASDs pose a major challenge to the identifi

174 f the microbiome and mode of delivery in the aetiology of asthma and other childhood wheezing disorde

175 The aetiology of atopic dermatitis is unknown, but the recen

176 pporting a developmental contribution to the aetiology of atopic eczema and pointing to potentially m

177 y twin and sibling studies to understand the aetiology of atopic march diseases.

178 er Pylori (H. pylori) infection plays in the aetiology of atopy remains unclear, although a possible

179 urons may, therefore, have a key role in the aetiology of autism spectrum disorder.

180 that defective genetic networks underlie the aetiology of autism, few have translated into pharmacoth

181 Genetics has a key role in the aetiology of autism, in conjunction with developmentally

182 innate immunity and neuronal activity in the aetiology of autism.

183 on mechanism for axon growth, and reveal the aetiology of axon-guidance defects in sax-3/Robo and vab

184 very that LTCC genes are part of the genetic aetiology of bipolar disorder and related phenotypes.

185 d link a subset of mammary stem cells to the aetiology of BLBC.

186 muscle satellite cell response is key in the aetiology of burn-induced cachexia.

187 ions provide key insights into the molecular aetiology of cerebellar defects in CHARGE syndrome and l

188 ingivalis (Pg) is a keystone pathogen in the aetiology of chronic periodontitis.

189 Our results elucidate the aetiology of CMCS and highlight a new molecular role for

190 has a great potential for understanding the aetiology of common complex traits such as Type 2 diabet

191 (SNPs) in the search for underlying genetic aetiology of complex disorders.

192 (-9)), providing additional insight into the aetiology of CRC and highlighting the value of associati

193 Diet is strongly associated with the aetiology of Crohn's Disease (CD) and exclusive enteral

194 The aetiology of Crohn's disease is complex and may include

195 results suggest possible differences in the aetiology of depression between women and men.

196 ted in depression and may be involved in the aetiology of depressive symptoms and vulnerability to de

197 sed glycemic load has been implicated in the aetiology of diabetes.

198 The aetiology of diabetic retinopathy (DR), the leading caus

199 tterns becomes particularly important in the aetiology of different diseases including cancers.

200 much progress has been made to elucidate the aetiology of disease processes in cancer, the contributi

201 g but also may be of utility in studying the aetiology of disease.

202 n of beta-dystroglycan as a key event in the aetiology of Duchenne muscular dystrophy.

203 The aetiology of dystonia was the sole factor predicting a b

204 blocking dystroglycan phosphorylation on the aetiology of dystrophin-deficient muscular dystrophy, th

205 The genetic aetiology of EM is largely unknown in the majority of ca

206 l overlap in genetic variants underlying the aetiology of endometriosis, WHRadjBMI and BMI using GWAS

207 itical role for carotid body tonicity in the aetiology of enhanced central respiratory modulation of

208 To understand the genetic aetiology of Fuchs endothelial corneal dystrophy (FECD),

209 rting of gastro-oesophageal symptoms and the aetiology of gastro-oesophageal reflux disease (GORD) re

210 will focus on recent advances in the genetic aetiology of glycaemic traits, and the resulting biologi

211 Our findings provide insight into the aetiology of hernia development and highlight genetic pa

212 n is an important tool for understanding the aetiology of human disease.

213 The aetiology of human fibrolamellar hepatocellular carcinom

214 its high prevalence and economic burden, the aetiology of human hypertension remains incompletely und

215 o BP variance, and clarify the developmental aetiology of hypertension.

216 The aetiology of IBD is partly attributed to a deregulated i

217 r gene has previously been implicated in the aetiology of increased suicidal risk in non-HIV infected

218 We also briefly review aetiology of infantile nystagmus in afferent visual defi

219 ine recent developments in understanding the aetiology of infantile nystagmus.

220 The aetiology of intervertebral disc (IVD) degeneration rema

221 an integral role for satellite cells in the aetiology of lean tissue recovery following a severe bur

222 bacter pylori infection is implicated in the aetiology of many diseases.

223 iation in the HLA region is important to the aetiology of many disorders, it does not appear to be hi

224 oplasmic reticulum stress contributes to the aetiology of many human diseases.

225 d, therefore, they are not homologous in the aetiology of metabolic disease.

226 Besides, aetiology of nephrocalcinosis should be sought for and c

227 n neuroimmunology and sheds new light on the aetiology of neuroinflammatory and neurodegenerative dis

228 Such events may underlie the aetiology of neuroleptic associated cerebral oedema and

229 omatic inhibition is thought to underlie the aetiology of neurological dysfunction in seizures, autis

230 vidence implicates early life factors in the aetiology of non-communicable diseases, including asthma

231 entation, are believed to be involved in the aetiology of obesity and diabetes.

232 The aetiology of paucigranulocytic asthma is unknown.

233 found in painful small fibre neuropathy, the aetiology of peripheral neuropathy in many cases remains

234 sy and early ataxia syndrome and extends the aetiology of PMEs to include dysfunction in nuclear lami

235 this Personal View concerns pathogenesis and aetiology of psychiatric diseases.

236 ur findings may provide new insight into the aetiology of PTB and improve our ability to predict and

237 g this oncogenic transcription factor in the aetiology of radiogenic breast cancer.

238 ulated epigenetic variation in the molecular aetiology of schizophrenia, this study aimed to identify

239 t the involvement of neurodevelopment in the aetiology of schizophrenia.

240 on theory implicated these infections in the aetiology of several systemic diseases, ranging from art

241 enome-Wide Association Studies (GWAS) in the aetiology of sleep, mental health and metabolic disorder

242 A patients, raising the possibility that the aetiology of SMA is linked to RNA metabolism.

243 red, developmental stage with respect to the aetiology of social support.

244 psychosocial stress may be implicated in the aetiology of stroke.

245 The aetiology of stuttering remains unclear; compared to oth

246 ith the risk factors thought to underlie the aetiology of sudden infant death syndrome, including: (1

247 hile a consensus is yet to be reached on the aetiology of the biological activities of ABA several st

248 e of the biology of myocardial aging and the aetiology of the defective cardiac performance in the el

249 Aetiology of the disease is auto-immunological.

250 The aetiology of the disease is poorly understood, but parti

251 of adjacent genes, further complicating the aetiology of the disease.

252 , GRM7 and GRM8) have been implicated in the aetiology of the disorder and overlap with bioinformatic

253 the parasegment boundaries and explains the aetiology of the even-skipped null mutant phenotype.

254 ate moderately with general anxiety, but the aetiology of their association remains unexplored.

255 mplicating altered epigenome dynamics in the aetiology of these cancers.

256 ysteine levels that could participate in the aetiology of these diseases.

257 provides important insights into the genetic aetiology of this common craniofacial malformation.

258 tors can influence AAO may shed light on the aetiology of this complex disease, and have applications

259 lack of animal models that recapitulate the aetiology of this complex disease.

260 Although the underlying aetiology of this condition is unclear, there is circums

261 The aetiology of this differing mutation pattern is still un

262 cases of high myopia, implicating it in the aetiology of this disorder.

263 The aetiology of this is diverse but fibrosis within the tra

264 The aetiology of this syndrome has been enigmatic since the

265 pendent of dose, patient characteristics, or aetiology of TIA or stroke.

266 the involvement of infectious agents in the aetiology of type 1 diabetes in children.

267 The complex aetiology of type 2 diabetes makes effective screening,

268 with a causal role of BCAA metabolism in the aetiology of type 2 diabetes.

269 t roles in shaping food preferences; but the aetiology of variation in non-alcoholic beverage prefere

270 egulation of NADPH oxidase expression in the aetiology of vein graft failure.

271 ite its widespread and damaging effects, the aetiology of WBD remains largely unresolved.

272 ated with social and emotional deficits, the aetiology of which are not well understood.

273 ost RDEB patients experience daily pain, the aetiology of which is unclear but may include inflammati

274 ovides a novel pathogenomic insight into the aetiology of WHS by describing it, for the first time, a

275 ascular disease may be more important in the aetiology of young-onset dementia than previously believ

276 identification of genes involved in disease aetiology, often in conjunction with WGS filtering appro

277 Stroke of undetermined aetiology or 'cryptogenic' stroke accounts for 30-40% of

278 describe current insights into genetics and aetiology, pathophysiology, epidemiology, assessment, th

279 verely sight-impaired individuals of varying aetiologies performed a search task using a similar low-

280 es mainly associated with non-immune disease aetiologies, poor longitudinal clinical-serological corr

281 se outbreak, and the circumstances for their aetiology, potentially influence the trajectory of trans

282 developments in neuroimaging and detection, aetiology, prevalence, pathophysiology and clinical sign

283 ial implications for understanding of cancer aetiology, prevention and therapy.

284 zophrenia is a common disease with a complex aetiology, probably involving multiple and heterogeneous

285 cause substantial carer distress, but their aetiology remains elusive.

286 mately 2% of the world's population, but the aetiology remains incompletely understood.

287 most common subgroup of paediatric ALL, its aetiology remains unknown.

288 ith cryptogenic stroke to identify potential aetiologies such as cardiac thrombi, cardiac tumours, ao

289 man obesity epidemic might thus have a wider aetiology than currently accepted.

290 acute pancreatitis overall and for gallstone aetiology, the study factors had limited impact on morta

291 The diagnosis of stroke, its underlying aetiology, theranostic strategies, recurrence risk and p

292 eria-Scedosporium complex, is a contributing aetiology to tsunami lung and central nervous system inf

293 ed metabolic profiling may inform underlying aetiology via extensive associations with very-low-densi

294 qual incidence of malignant and inflammatory aetiologies was seen.

295 Chronic fatigue caused by other aetiology was diagnosed in 24.5% (13/53); five of these

296 The most common aetiology was squamous cell carcinoma and the majority o

297 f recurrent coding sequence variation in CRC aetiology, we genotyped 12,638 CRCs cases and 29,045 con

298 ife exposure to tobacco smoke and rhinovirus aetiology were early-life risk factors for later asthma.

299 Thus, EM has a genetic aetiology which overlaps variation in normal age at meno

300 chitecture of the TMT and its shared genetic aetiology with other tests of cognitive function in 23 8