ライフサイエンスコーパス: affective

1 oup differences were observed for cognitive, affective and behavioural impairment on psychosocial que

2 e frequent occurrence of stimulation-induced affective and cognitive adverse effects, a better unders

3 cent years, the neural mechanisms underlying affective and cognitive empathy have garnered intense in

4 euromodulator in the brain, is implicated in affective and cognitive functions.

5 bility of PV interneurons to MIA, leading to affective and cognitive symptoms that have high relevanc

6 tervention effects on cognitive, behavioral, affective and health services utilization outcomes were

7 Our results demonstrate that affective and informative reward properties are encoded

8 We approached this problem by emphasizing affective and informative reward properties within two i

9 rt a neural substrate for ILPFC/BA25 linking affective and motivational circuitry dysfunction in MDD.

10 rovides a common framework for understanding affective and neurocognitive dysfunctions across multipl

11 easures relating to sensorimotor processing, affective and nonaffective cognition, mental health and

12 of specific psychotic symptoms, relative to affective and other symptoms, and their sequence and dur

13 ct modulated functional interactions between affective and perceptual regions early during perceptual

14 Participants rated their affective and sensory experiences following bolus infusi

15 Sh circuit may underlie hippocampal-mediated affective and social behavioral disturbances present in

16 udy of sexual arousal is at the interface of affective and social neurosciences.

17 of harms engaged brain areas associated with affective and somatosensory processing, whereas mental s

18 dfulness interventions on health, cognitive, affective, and interpersonal outcomes; (b) evidence-base

19 asizes the neurobiological pathways by which affective arousal tunes attention and memory.

20 As predicted, the provision of slow-affective, as compared to fast-neutral, touch led to a s

21 ical regions implicated in the processing of affective auditory cues.

22 aried as a function of how well the target's affective behavior matched the observer's neural represe

23 sion using in vivo quantitative PCR and with affective behavior using a primate test of anxiety (huma

24 on can change while they observe the other's affective behavior, and that these changes depend on the

25 ontribute to the effects of BMP signaling on affective behavior.

26 activity which may play a role in modulating affective behavior.

27 o-inflammatory markers can directly modulate affective behavior.

28 tokine response and associated cognitive and affective behavioral changes.

29 mpal neurogenesis and promotes cognitive and affective behavioral deficits.

30 output functions and can generate emotional-affective behaviors and modulate nocifensive responses.

31 bolic disturbances and disrupt cognitive and affective behaviors.

32 Female donors had higher affective (beta = 0.88, P = 0.005) and adverse effects s

33 Affective bias, the tendency to differentially prioritis

34 utational framework, we investigated whether affective biases may reflect individuals' estimates of t

35 Normalising affective biases using computationally inspired interven

36 e that the aIPS contains a representation of affective body movements.

37 ating that aIPS contains a representation of affective body movements.

38 aIPS contains an explicit representation of affective body movements.SIGNIFICANCE STATEMENT In human

39 A number of behavioural and affective changes were reported more frequently in bvFTD

40 ay lead to impairment of these cognitive and affective circuits.

41 sychological account of a high-level, social-affective cognitive facet that joins forces with recent

42 her brain regions implicated in sensoimotor, affective, cognitive and pain processing functions throu

43 enotypically and genetically associated with affective, cognitive, personality and physiological proc

44 nervosa (AN) and obesity are complicated by affective comorbidities and hypothalamic-pituitary-gonad

45 morphine, PZM21 is more efficacious for the affective component of analgesia versus the reflexive co

46 on of serotonergic transmission controls the affective component of inflammatory pain.

47 The affective component of pain is mediated by circuits that

48 Recent progress in Affective Computing (AC) has enabled integration of phys

49 xtent to which PC impacts both cognitive and affective conflict control at different temporal stages.

50 However, few studies have examined whether affective conflict processing is modulated as a function

51 lved in regulating food intake and resolving affective conflict, respectively.

52 Our findings suggest that cognitive and affective conflicts engage early dissociable attentional

53 ies, we investigated cognitive versus social-affective context effects on the stable and time-varying

54 e effects of age and cognitive versus social-affective context on the stable and time-varying neural

55 A dynamic social-affective context-specific signature was observed most c

56 ges at specific times of year and changes in affective control in vulnerable populations.

57 main role in present AC studies when fusing affective cues or modalities, resulting in unexpected ou

58 d anterior cingulate in response to negative affective cues, as well as during emotion regulation.

59 trate a dynamic correlation between two such affective cues, physiological changes and spontaneous ex

60 ease, which can influence important forms of affective decision-making.

61 a stronger negativity bias during ambiguous affective decision-making.

62 , the specific mechanisms linking valuation, affective deficits, and maladaptive decision making in p

63 vestigated the role of prostaglandins in the affective dimension of pain using a rodent pain assay ba

64 processing and even that primitive internal affective dimensions (e.g., goodness-to-badness) are rep

65 subjective experience than commonly measured affective dimensions (e.g., valence and arousal).

66 thers-that correspond to smooth variation in affective dimensions such as valence and dominance.

67 was to estimate the incidence of postpartum affective disorder (AD), duration of treatment, and rate

68 f a schizophrenia spectrum (ICD10 F20-29) or affective disorder (F30-39 with psychotic symptoms), and

69 eficit/hyperactivity disorder (N=18 726) and affective disorder (N=26 380), of which 1928 had bipolar

70 public health challenge for winter seasonal affective disorder (SAD) is recurrence prevention.

71 and sleep/mood disorders, including seasonal affective disorder (SAD).

72 mplicating dopamine dysregulation in bipolar affective disorder and schizophrenia, in line with the r

73 Bipolar affective disorder is a common neuropsychiatric disorder

74 he Hamilton Depression Rating Scale-Seasonal Affective Disorder Version (SIGH-SAD).

75 sorder (N=26 380), of which 1928 had bipolar affective disorder.

76 Lithium is a first-line therapy for bipolar affective disorder.

77 responding and via that route predispose for affective disorder.SIGNIFICANCE STATEMENT Previously pro

78 g 3 vulnerable populations: individuals with affective disorders (n = 56) or opioid dependence (n = 6

79 hizophrenia, anxiety disorder, OCD, and most affective disorders also showed mean dissociation scores

80 t ketamine exposure of pregnant rats induces affective disorders and cognitive impairments in offspri

81 rrent mental disorder using the Schedule for Affective Disorders and Schizophrenia for School-Age Chi

82 rstand the underlying brain abnormalities in affective disorders and target more effective treatments

83 eful tools for the differential diagnosis of affective disorders and the prediction of both treatment

84 spite the growing literature suggesting that affective disorders can arise after a traumatic event is

85 onist agents together with stress related to affective disorders emphasize the pathogenic role of sym

86 (ACEs) are one of the greatest predictors of affective disorders for women.

87 isk among psychiatric inpatients with severe affective disorders from an estimated 12.3% among indivi

88 atment approach or augmentation strategy for affective disorders including anxiety disorders and majo

89 ctor for the exacerbation and development of affective disorders including major depression and postt

90 sensory signaling may have implications for affective disorders that include sensory dysfunctions li

91 s known about the neural correlates of these affective disorders when they occur in mothers, but they

92 enia, schizoaffective disorders, and bipolar affective disorders) is well described, but little is kn

93 ding developmental disorders, schizophrenia, affective disorders, and Alzheimer's disease.

94 ences in stress reactivity, vulnerability to affective disorders, and response to pharmacotherapy.

95 iated with schizophrenia spectrum disorders, affective disorders, anxiety disorders, and other neurot

96 intellectual disability, schizophrenia, mood affective disorders, anxiety disorders, autism spectrum

97 sociated with other substance use disorders, affective disorders, anxiety, and personality disorders.

98 ive HPA stress axis, an important feature of affective disorders, during a dynamic hormonal period, a

99 atment available for individuals with severe affective disorders, ECT's availability is limited and d

100 d sets off a general alarm system as seen in affective disorders, such as chronic anxiety and post-tr

101 ons among psychiatric inpatients with severe affective disorders.

102 possible predictor of treatment response in affective disorders.

103 ses to potential threat is a core feature of affective disorders.

104 multistate sample of inpatients with severe affective disorders.

105 Serotonin is implicated in mood and affective disorders.

106 licated in the pathogenesis and treatment of affective disorders.

107 ot all individuals exposed to stress develop affective disorders.

108 ance to suppression of emotional memories in affective disorders.

109 obstructive pulmonary disease, migraine, and affective disorders.

110 ight into the role of these brain regions in affective disorders.

111 l (HPA) axis dysregulation, a key feature of affective disorders.

112 tic implications for circadian disruption in affective disorders.

113 JNK as an avenue for novel therapies against affective disorders.Molecular Psychiatry advance online

114 uated the impact of PTSD symptom severity on affective distress, although this effect was not found a

115 including pregnancy, exacerbate the risk for affective disturbance and promote hypothalamic-pituitary

116 (MAG) lipase inhibitor JZL-184 also reduced affective disturbances in the NSFT in ethanol withdrawn

117 We were able to reverse affective disturbances measured in the NSFT following Et

118 lso domain-general processing styles and the affective drive to create.

119 on psychopathy has focused largely on socio-affective dysfunction, recent data suggest that aberrant

120 antly reduces the permanent neurological and affective effects of CO poisoning, a portion of survivor

121 es for pain severity, activity interference, affective (emotional) reactions, adverse effects to trea

122 ompleted a behavioural task to measure state affective empathy and emotion recognition.

123 and apathy are distinct constructs, but that affective empathy and emotional motivation are underpinn

124 demonstrate highly specific roles of AI for affective empathy and TPJ for cognitive perspective taki

125 donation behavior was heavily influenced by affective empathy exhibited higher predictive accuracies

126 In contrast, affective empathy was associated with lower levels of be

127 tural integrity of the insular cortex, while affective empathy was predicted by a marker of iron cont

128 ct processes for altruistic decision-making (affective empathy, cognitive perspective taking, and dom

129 neuroanatomical correlates of cognitive and affective empathy.

130 d rate of subsequent postpartum AD and other affective episodes in a nationwide cohort of women with

131 outcomes which may bias their processing of affective events.

132 vs. threat) that is distinct from conscious affective experience and more closely tracks the neurobi

133 might capitalize on an overlooked aspect of affective experience: current emotions predict future em

134 n is its ability to impact other sensory and affective experiences.

135 while subjects performed both cognitive and affective face-word Stroop tasks.

136 Here, a novel aspect of affective facilitation of attention is studied: whether

137 ents of the brain circuitry underlying human affective function and decision-making.

138 cated in a variety of social, cognitive, and affective functions that are commonly disrupted in menta

139 eartbeat dynamics, to instantaneously assess affective haptic perception using electrocardiogram-deri

140 eatures were able to finely characterize the affective haptic perception, with a recognition accuracy

141 egiving, may change the way women respond to affective, infant signals in their environments.

142 stantial empirical support for the idea that affective influences infiltrate the earliest reaches of

143 ral correlates underlying the integration of affective information conveyed by faces and bodies.

144 tention provide evidence that we make use of affective information during perceptual processing.

145 nce of a neural representation selective for affective information in biological motion.

146 cation of heuristics for both structural and affective information.

147 It is unclear how this affective instability is associated with information pro

148 s (10 times a day for 6 days) and calculated affective instability using the mean adjusted absolute s

149 DD patients compared with HCs, we found that affective instability was increased in most negative moo

150 but the role of the AOS' areas in processing affective kinematic information has never been examined.

151 he role of these brain regions in processing affective kinematic information has not been investigate

152 However, like many affective labels, it could be that "contempt" refers bot

153 While affective lability and anxiety/depression were elevated

154 path analysis supported the hypothesis that affective lability at baseline predicts a new-onset bipo

155 tion, externalizing, subsyndromal manic, and affective lability symptoms.

156 While youths without anxiety/depression, affective lability, and mania (and with a parent with ol

157 Dimensional measures of anxiety/depression, affective lability, and mania are important predictors o

158 ne anxiety/depression, baseline and proximal affective lability, and proximal subsyndromal manic symp

159 There is well-known heterogeneity in affective mechanisms in depression that may extend to po

160 eport measures of mindfulness (Cognitive and Affective Mindfulness Scale-Revised), coping (Measure of

161 According to affective monitoring, competition raises arousal, which,

162 s (cognition/planning, initiation, emotional-affective/motivation) with specific neuroanatomical and

163 untary actions, and possibly some aspects of affective motor repertoire, but the role of the AOS' are

164 ed behavioral adaptation effects of observed affective movements.

165 in the default mode, cognitive control, and affective networks.

166 adolescence may be a critical element of the affective neurobiological characteristics underlying sex

167 ed on evolutionary theory, a recent model in affective neuroscience delineated six emotional brain sy

168 Affective neuroscience has generally treated prefrontal

169 This review summarizes how preclinical affective neuroscience initiatives are making progress i

170 To date, most investigations in the field of affective neuroscience mainly focused on the processing

171 The Affective Neuroscience Personality Scales (ANPS) assess

172 have recently been used within the field of affective neuroscience to classify distributed patterns

173 d in the cognitive task but decreased in the affective one.

174 ensory processing, depending on the animal's affective or motivational state.

175 living human brain unaffected by cognitive, affective, or social manipulations.

176 known as model-based control, is based on an affective outcome relying on a learned internal model to

177 t sizes were found in relation to changes in affective outcomes.

178 ole in expression of an underlying infradian affective "pacemaker." The authors attempted to determin

179 ical and thermal hypersensitivity, decreased affective pain behaviors, and strongly reduced hyperalge

180 achial nucleus (PBL), a critical node in the affective pain circuit, is activated more strongly by no

181 ion Rating Scale, Beck Depression Inventory, Affective Pain Rating Index of the Short-Form McGill Pai

182 neural substrate for heightened craniofacial affective pain.

183 ers a holistic and parsimonious way to study affective personality dimensions.

184 It can render some complex affective phenomena theoretically tractable, help refine

185 ral connectivity signature of a cognitive or affective predisposition may similarly vary across diffe

186 that guides children's attention toward and affective preferences for attractive females.

187 suggests that sensory, motor, cognitive and affective processes map onto specific, distributed neura

188 cerebellar contribution to the cognitive and affective processes that are compromised in neurodegener

189 as motor activity, cognitive functions, and affective processes.

190 TA) are strongly implicated in cognitive and affective processing as well as in psychiatric disorders

191 insight into the role stress plays in basic affective processing for healthy and clinical population

192 ribution to diverse domains of cognitive and affective processing in human health and disease.

193 d to harmonise with the social environment), affective processing, and brain plasticity, which underl

194 Notably, affective properties modulate emotion while informative

195 MJN110 and the CB1 antagonist (AM251) on the affective properties of MWD.

196 a diagnosis of first-episode non-organic or affective psychosis according to ICD-10 criteria, and we

197 ticipants who were aged 16-35 years, had non-affective psychosis, had been clients of early intervent

198 ental health services and a diagnosis of non-affective psychosis, which are markers of severity of me

199 iologic contributions to the neurobiology of affective psychosis.

200 In both cohorts, non-affective psychotic disorders (adjusted hazard ratio [HR

201 analyses of neighbourhood variations of non-affective psychotic disorders (NAPD) have focused mainly

202 es: high anxiety, low mood, combined and non-affective (psychotic).

203 and affect, suggesting that S1 also encodes affective qualities.

204 unctional interference, adverse effects, and affective reaction subscale scores (beta range 1.06-1.55

205 t lend themselves to distancing have initial affective reactions similar to those of novices, who lac

206 y were rated by both parent and child on the Affective Reactivity Index and Screen for Child Anxiety

207 e to subgroup A), particularly among ventral affective regions.

208 However, despite exhibiting intact affective regret sensitivity, they did not use prospecti

209 8.00 [15.55] vs 27.14 [18.39]; p=0.035), and affective regulation (mean Dysfunction in Emotional Regu

210 s were body-mass index (BMI), mood, anxiety, affective regulation, and anorexia nervosa-specific beha

211 , the processes involved in the appraisal of affective relevance.

212 I argue that prejudice is an affective representation of a social group's relational

213 rior cingulate cortex, suggesting a stronger affective response toward errors in patients with OCD.

214 ment effect indirectly by modifying negative affective responses in the context of selling.

215 he role of the mu-opioid system in mediating affective responses to high-intensity training as oppose

216 crine stress response patterns are linked to affective responses to stress and structural variability

217 r relationships among endocrine, neural, and affective responses to stress have generally yielded inc

218 in the hippocampus to regulate cognitive and affective responses to the challenge.

219 Affective responses to the taste cue were measured using

220 uld be used to predict decisions to regulate affective responses to those images.

221 inks between cortisol response to stress and affective responses, as well as hippocampal structural v

222 chopathy have largely focused on deficits in affective responsiveness, recent work indicates that abe

223 We propose that the affective reversal of sadness in music is due to the hig

224 to a musical experience as well as cases of affective reversal, such as the "hedonic flip" of painfu

225 vity between voice-selective STS and reward, affective, salience, memory, and face-processing regions

226 n), quality of life measures, disability and affective scores.

227 Thus, the re-experiencing phenomena and affective sequelae in combat-related PTSD may result fro

228 The relationship of drug-related affective sequelae to non-drug reward processing suggest

229 oning suffer from long-term neurological and affective sequelae.

230 functions with and without motivational and affective significance; and in a subgroup of youths with

231 receptors (AMPARs) contribute to somatic and affective signs of opiate withdrawal is not fully unders

232 on the cheek in synchrony or asynchrony with affective (slow; CT-optimal) vs. neutral (fast; CT-subop

233 Misophonia is an affective sound-processing disorder characterized by the

234 world and the current findings showing that affective sounds could influence visual attention provid

235 However, evidence on the impact of affective sounds on perception and attention is scant.

236 a-spectrum disorder, delusional disorder, or affective-spectrum psychotic disorder, and psychotic sym

237 sures of social cognition and communication (affective speech recognition (ASR), reading the mind in

238 in multiple outcome measures related to the affective sphere of pain (eg, Montgomery-Asberg Depressi

239 ng limbic neural pathways would modulate the affective sphere of pain and alleviate suffering.

240 INTERPRETATION: VS/ALIC DBS to modulate the affective sphere of pain represents a paradigm shift in

241 on multiple outcome measures related to the affective sphere of pain.

242 k on neuromodulation therapies targeting the affective sphere of pain.

243 fect of acute administration on the negative affective state after acute drug withdrawal.

244 idence that the effects of KOR activation on affective state are biphasic: immediate aversive effects

245 es in reward circuitry leading to a negative affective state contributing to addictive behaviors and

246 e data support a model in which the negative affective state following acute amphetamine withdrawal i

247 across modalities.SIGNIFICANCE STATEMENT The affective state is increasingly understood to influence

248 eward, a cellular substrate for the negative affective state of loneliness has remained elusive.

249 ation for Suicidality (CFI-S) and Simplified Affective State Scale (SASS), previously tested in men,

250 ) and for anxiety and mood (SASS, Simplified Affective State Scale)) by themselves, as well as in com

251 abulary" is suited to infer another person's affective state, and that this intrinsic reward might be

252 damentally unpleasant and induces a negative affective state.

253 e in having correctly understood the other's affective state.

254 of drug-associated cues, but also a negative affective state.

255 inform us about some aspects of the infant's affective state.

256 er's neural representation of the underlying affective state: The greater the match, the larger the b

257 on, audiovisual hallucinations, and negative affective states akin to those reported for MDPV-induced

258 ccumbens (NAcc) powerfully mediates negative affective states and stress reactivity.

259 tracking odor trails, and our behavioral and affective states are influenced by our sense of smell.

260 IP3K-A plays an important role in regulating affective states by modulating metabotropic receptor sig

261 Negative affective states can increase the rewarding value of dru

262 , which is necessary for triggering negative-affective states in response to naloxone.

263 The impact of KOR-induced affective states on reward-related effects of cocaine ov

264 closely than they do self-reported internal affective states such as stress, depression, or anxiety.

265 e and withdrawal result in profound negative-affective states that play a major role in the maintenan

266 NAc), a brain region critical for modulating affective states, are necessary for aversive effects of

267 ing the switch between positive and negative affective states, wherein several neurochemicals converg

268 rofound effects on brain areas that regulate affective states.

269 cts of nicotine on cognition, attention, and affective states.

270 Exposure to affective stimuli could enhance perception and facilitat

271 Alterations in neural processing of negative affective stimuli have further been demonstrated among i

272 l arousal, and enhances visual perception of affective stimuli.

273 c" structures, such as the amygdala, process affective stimuli.

274 Affective symptoms influence health status (health-relat

275 controls (HC) and negatively associated with affective symptoms throughout the weight spectrum, indep

276 hesised that self-reported health status and affective symptoms would map onto salience network regio

277 th significant and sustained improvements in affective symptoms, BMI, and changes in neural circuitry

278 phase of the menstrual cycle may precipitate affective symptoms.

279 roportion congruency context, whereas in the affective task it was found to occur in the high proport

280 fects were specific to cognitive rather than affective ToM.

281 ToM, extending previous findings concerning affective ToM.

282 ion, and suggest a specific relation between affective touch and social bonding.

283 Nevertheless, no study has examined whether affective touch can also modulate psychological identifi

284 Overall, our data suggest that CT-optimal, affective touch enhances subjective (but not behavioural

285 Growing interest in affective touch has delineated a neural network that byp

286 We discuss the role of affective touch in shaping the more social aspects of ou

287 illusion paradigm to investigate the role of affective touch in the modulation of self-face recogniti

288 examine whether the administration of slow, affective touch may reduce the negative feelings of ostr

289 dy contributes to growing delineation of the affective touch system, a crucial step in understanding

290 However, it remains unknown whether slow, affective touch, can also reduce feelings of social excl

291 ity that gives rise to feelings of pleasant, affective touch, can enhance the experience of body owne

292 ings point to the soothing function of slow, affective touch, particularly in the context of social s

293 Recent studies suggest that slow, affective touch, which is mediated by a separate, specif

294 ft AI and mACC, pointing to common coding of affective unpleasantness, but also response patterns spe

295 traditionally associated with processing the affective valence (negative vs positive) of an emotional

296 ects goal-directed learning as a function of affective valence.

297 evel descriptions and selective attention to affective value, modulate the representation of the rewa

298 nsive experience with a US that had positive affective value.

299 (vmPFC) was parametrically modulated by the affective values of items in participants' memories when

300 d is defined by the emergence of somatic and affective withdrawal signs.