ライフサイエンスコーパス: against

1 LTxR with AR, 7 with BOS, and compared them against 13 stable pediatric LTxR at 1, 6, and 12 months

2 eudotyped viruses with neutralization titers against 16 broadly neutralizing antibodies and 30 sera f

3 Against a backdrop of rapidly increasing temperatures an

4 positive selection on the ND2 and ND5 genes against a background of purifying selection across the m

5 identify a CD4 T cell response to ovalbumin against a background response to the complex mixture of

6 uction to sulfide were measured and compared against a commercial sensor giving no significant differ

7 es were isolated using a monoclonal antibody against a hepatic surface protein, leucine amino peptida

8 molar GI50 values (16o, mean GI50 of 3.3 nM) against a large number (93) of cancer cell lines.

9 odies (VNAs), resulting in better protection against a lethal challenge than that seen with rLBNSE.

10 ltant lead compounds possess potent activity against a multidrug resistant strain of P. falciparum an

11 We compared the foveated object detector against a non-foveated version of the same object detect

12 fore striatal binding ratios were quantified against a normal database.

13 esting selective theories of language change against a null model and reveals an underappreciated rol

14 ent redirection of CD4(+) and CD8(+) T cells against a panel of established blood cancers and primary

15 karyotic cell which maximizes its protection against a viral attack.

16 The adjusted VE against A(H1N1)pdm09 was 43% (95% confidence interval [C

17 wo analogues when used alone lacked activity against Acinetobacter baumannii and Klebsiella pneumonia

18 e found that recombinant I62-CFH (protective against age-related macular degeneration) and V62-CFH fu

19 imulated IGF-1R, but protecting the receptor against agonist-induced degradation.

20 enous Treg, IVIg failed to confer protection against AHR and airway inflammation.

21 ibodies with HAI and neutralization activity against all cocirculating variants from 2004 to 2007.

22 s showed rapid bactericidal effect of LyeTxI against all periodontopathogens.

23 Human homologs of top-ranked hits protected against alphaSyn-induced cell death in a human neuronal

24 d fragment-based and high-throughput screens against an amino-sugar acetyltransferase enzyme, PglD, i

25 romising new therapeutic strategy to protect against anticancer drug-induced peripheral neurotoxicity

26 litate future development of pharmaceuticals against antithrombin polymerization, an improved underst

27 Estrogens protect against apoptosis of endothelial cells (ECs), one of the

28 Validation against approximately 600 experimental mutations indicat

29 a lipophilic prodrug with nanomolar activity against asexual parasites.

30 ls function in adaptive immunological memory against B. pertussis.

31 ciated with an increased antibiotic activity against bacterial strains possessing high level vancomyc

32 ptive immune systems that provide protection against bacteriophage (phage) and other parasites.

33 ssessment of the resistance that PAs provide against biological invasions and climate change on a con

34 pect to growth and morphogenesis and defense against biotic and abiotic stress.

35 e identified a potent neutralizing antitoxin against BoNT/A1 termed ciA-C2, derived from a camelid he

36 a secreting total T cells, T-helper and CTLs against both H1N2 and H1N1 SwIV.

37 zomib and doxorubicin were observed in vitro against both multiple myeloma and ovarian cancer cells.

38 suggest LIP ultrasound stimulation protects against brain injury in the hippocampus and corpus callo

39 own anticarcinogenic effects, but protection against breast cancer has not been established.

40 ry of L. reuteri with glycerol was effective against C. difficile colonization in complex human fecal

41 fibers that reacted with a labeled antibody against calcitonin gene-related peptide (CGRP), a marker

42 set retina can be identified with antibodies against calretinin.

43 ules with the efficacy of a molecule process against cancer cells, this work provides an important in

44 pression of DLST in wild-type mice protected against cardiac hypertrophy and dysfunction in vivo.

45 acterial taxa was correlated with protection against CDI: Bacteroidetes, Lachnospiraceae, and Ruminoc

46 outcomes, with male circumcision protecting against cervical cancer, cervical dysplasia, herpes simp

47 st that early-life farming exposures protect against childhood asthma and allergy; few data exist on

48 gets for the development of antiviral agents against chronic HBV infection.

49 bates, whereas MIOX gene disruption protects against, cisplatin-induced AKI.

50 itions along with the anti-swarming activity against Citrobacter rodentium.

51 ety of bacteria causing it, their resistance against classical antibiotics, the formation of a biofil

52 nd enhanced the activity of colistin in vivo against colistin-resistant P. aeruginosa.

53 ooperative symbionts can stabilise mutualism against collapse, but also present a paradox - if discri

54 sting a nutraceutical potential in the fight against colon cancer.

55 and retained significant inhibitory effects against colon carcinoma (CaCo-2) cells.

56 f terpenes, exerts growth inhibitory effects against colon carcinoma, suggesting a nutraceutical pote

57 roles in sensing the environment, protecting against colonization and infection of pathogens, and gui

58 sessing synergistic activity with leucovorin against colorectal cancer cells.

59 The development of vaccines against complex intracellular pathogens, such as Plasmod

60 prophylaxis (PfSPZ-CVac), and were protected against controlled human malaria infection.

61 eficiency of APOC3 has been shown to protect against coronary heart disease; we identified APOC3 homo

62 ory drugs or small interfering RNAs (siRNAs) against COX-1 and COX-2, significantly reduced PGE2 prod

63 First-surgeon recommendation against CPM does not appear to substantively increase pa

64 4-fold increase in immunoglobulin G directed against Cryptosporidium gp15 and/or Cp23 antigens betwee

65 irectional domain wall (DW) motion along and against current flow direction in Co/Pt double stack wir

66 ildren worldwide but no vaccine is available against CVA6 infections.

67 lizing antibody to correlate with protection against dengue virus have highlighted the need for a hum

68 oaches that can provide long-term protection against dengue virus infection is needed.

69 ification of robust correlates of protection against dengue virus.

70 to have a role in explaining the protection against depression.

71 the initiation of T helper 1 (TH1) immunity against dietary gluten and celiac disease (CeD).

72 y of protective action of CRISPR-Cas systems against different viruses should vary.

73 um concentrations of PFASs and of antibodies against diphtheria and tetanus were measured and were co

74 e are sufficient to provide broad protection against divergent virus strains in vivo.

75 at glycoside hydrolases can exhibit activity against diverse microorganisms and may be useful as ther

76 Thus, PKM2 activation may protect against DN by increasing glucose metabolic flux, inhibit

77 developed synthetic technologies and tested against drug-resistant bacterial strains.

78 cing the target electrostatics are validated against drug-target affinity data, yielding superior com

79 s in screening against one of two gp120s and against DS-SOSIP, which mimics the native trimer.

80 LY3023414 demonstrates efficacy against EAC in a preclinical model, establishing the rat

81 t methods of revascularization (PCI or CABG) against each other or medical treatment in patients with

82 fied ppGalNAc-T3 with no detectable activity against either ppGalNAc-T2 or ppGalNAc-T6.

83 SseK3 and NleB2 were not active against either substrate.

84 S determination of MC-LR was cross validated against ELISA.

85 Eruptions are associated with revolt onset against elite rule, and the cessation of Ptolemaic state

86 Moreover, they are potent against endogenous AC in intact melanoma cells.

87 f nutrients on the one hand, and for defence against endogenous and environmental stresses on the oth

88 t hydralazine has neuroprotective properties against endogenous and exogenous stressors.

89 These results caution against estimating protein fold-changes from mRNA fold-c

90 pared the accuracy and efficiency of PALADIN against existing tools that employ nucleotide or protein

91 mastic oil induces tumor-suppressing effects against experimental colon cancer.

92 ured coatings demonstrate enhanced stability against extreme external stressors, including organic so

93 uides to aid in design of vaccine strategies against fast mutating pathogens.

94 nucleases are powerful weapons in the fight against foreign DNA, such as phages and plasmids, as wel

95 nogenicity, and easy synthesis, aptamer GR-3 against GCGR can be a promising tool with the potential

96 erence explains why antibodies are effective against glioblastoma but generally fail in brain metasta

97 emozolomide, a clinical DNA-alkylating agent against glioma, 6OTD required lower concentrations to ex

98 suggested that the 18B7 monoclonal antibody against glucuronoxylomannan (GXM), the major component o

99 Individuals with low titers against group 3 pneumococcal surface protein C (PspC) va

100 lved in providing long-term cross-protection against H3N2 influenza virus when compared to other vacc

101 High titers of ADCC-Abs against H7N9 virus-infected cells were detected in sera

102 ld inform rational design of countermeasures against HCMV, other herpesviruses, and even HIV/AIDS.

103 h and potency of the humoral immune response against HCV.

104 own products are involved in stress response against herbivores, pathogens, and abiotic stress.

105 rved fusion protein contribute to protection against heterologous CDV strains.IMPORTANCE Rabies virus

106 ecific immune responses with limited potency against heterologous viral strains and genotypes.

107 tericidal activity of Ceftriaxone/Cefotaxime against highly pathogenic MRSA infection.

108 vo DT-CMR measures of cardiac microstructure against histology, characterize microstructural dynamics

109 s gRNAs were screened for their efficiencies against HIV provirus in these cells.

110 accine trial elicited significant protection against HIV-1 acquisition, but the efficacy and immune m

111 mmune memory, suggesting possible protection against HPV vaccine types after a single dose of 4vHPV.

112 We propose that LKB1 acts as a safeguard against HPV-stimulated aerobic glycolysis and tumor prog

113 molecule inhibitors with greater specificity against hRRM1 is a key step in the development of more e

114 DEXxDSy showed high effectiveness against HSV-1 and HSV-2 viruses, as found using a variet

115 been identified as a novel, potent inhibitor against human 11beta-hydroxysteroid dehydrogenase type 1

116 ll molecules targeting epigenetic modulators against human metastatic melanoma cells.

117 boxylate of polyketide origin, with activity against human opportunistic food pathogenic microbes, ha

118 sing safe, effective, and durable protection against human Zika virus infections or syndromes.

119 f providing structure-activity relationships against hundreds of targets simultaneously.

120 y to promote angiogenesis and to protect ECs against hydrogen peroxide-induced oxidative stress.

121 r secretion (anti-incretin effect) to defend against hyperinsulinemia-hypoglycemia.

122 ny non-vertebrate taxa and may protect cells against hypoxia and oxidative stress.

123 both specific for object identity and robust against identity-preserving transformations, like depth

124 lthough public goods producers were selected against in all populations, our competition experiments

125 umor samples, and by benchmarking the method against independent experimental data.

126 provide immune-surveillance and host defense against infection and cancer.

127 bodies to HIV that were partially protective against infection, as well as antibodies to HSV.

128 ls) are innate-like lymphocytes that protect against infection, autoimmune disease and cancer.

129 Neutrophils, the front line defenders against infection, express four serine proteases (NSPs)

130 Inflammation is a host defense process against infection.

131 antibody titer geometric mean fold increase against influenza B and (2) lower seroconversion rates a

132 fluenza B and (2) lower seroconversion rates against influenza H1N1 than noncolonized participants wi

133 used successfully to induce broad protection against influenza viruses in humans, and our limited dat

134 ting, is the primary physical airway defense against inhaled pathogens and irritants.

135 ooster dose to sustain individual protection against invasive meningococcal disease.

136 une system in archaea and bacteria to defend against invasive nucleic acids from phages and plasmids.

137 y among them the low contrast of the whisker against its background.

138 protective role that pathogenic ataxin-3 has against itself, which depends on the co-chaperone, DnaJ-

139 s of B. bacteriovorus acting therapeutically against K. pneumoniae in serum, informing future researc

140 erging treatment concepts use drugs directed against KIT and other relevant targets in neoplastic mas

141 Our goal was to evaluate this test using PB against larger numbers of Enterobacter A total of 143 no

142 fibrotic liver exert the protective effects against lethal insults through conferring apoptosis resi

143 stress-response-attenuated strain, protected against lethal TB in macaques.

144 superior protection and lung viral reduction against lethal viral challenge.

145 development of combined modality treatments against liposarcoma in recent years, a significant propo

146 otein precursor-knockout mice were protected against lithium-induced iron elevation and neurotoxicity

147 we performed a chromatin immunoprecipitation against Lmx1b in mouse limbs at embryonic day 12.5 follo

148 tion, the printed black phosphorus is stable against long-term (> 30 days) oxidation.

149 able to orchestrate an inflammatory response against LPS and expressed three factors reported to cont

150 xpresses IFN-gamma and can confer protection against M. avium infection in immunocompromised mice.

151 merozoites to be associated with protection against malaria and further shows IgG3 and GLURP antibod

152 antagonistic trait (spine length, a defence against males), as well as body size.

153 nsity, the AMPs exhibited inhibited toxicity against mammalian cells.

154 microbiota provides colonization resistance against many orally acquired pathogens, and antibiotic-m

155 texana was found to have selective activity against MDA-MB-453 cells, a model of the luminal androge

156 Our model is calibrated against measurements available in the literature.

157 nsion of adoptively transferred CD8+ T cells against melanoma.

158 There are no treatment options against MERS-CoV for humans or animals, and there are no

159 no large-scale clinical trials for therapies against MERS-CoV.

160 We calibrate residential energy use against metered data, accounting for differences in buil

161 hway are involved in plant defense machinery against microbial pathogens in Arabidopsis thaliana.

162 vation barrier to prevent unwanted reactions against minor allergens.

163 and that SS31 may confer protective effects against mitochondrial and synaptic toxicities in APP tra

164 d probed for reactivity with ferret antisera against MN/10 and BJ/92 in hemagglutination inhibition a

165 nstrated dominant ADCP activity of anti-gp41 against monomers but not trimers, with some higher activ

166 e primary use of mTORis as protective agents against most other cancer types.

167 Although VSV is effective against most PDAC cells, some are highly resistant to VS

168 emia cells and was therapeutically effective against mouse xenograft models of human leukemia.

169 APK blockade may be particularly efficacious against mPCs with an AR-null phenotype.

170 gion of interest for each tumor were plotted against MR ADC values.

171 nds were designed, synthesized and evaluated against MRSA and menaquinone utilizing bacteria in aerob

172 es were synthesized and tested as inhibitors against muscle and liver isoforms of glycogen phosphoryl

173 DOT1L inhibitors as novel anticancer agents against MYCN-amplified neuroblastoma.

174 Thus, augmenting host immune responses against Mycobacterium tuberculosis by harnessing the SET

175 improved in vitro and intracellular potency against Mycobacterium tuberculosis, including multidrug-

176 h VPC reversed the protective effects of VPC against neuroinflammation.

177 ndent Mg(2+) homeostasis protects Salmonella against nitrooxidative stress.

178 te (ABC) transporter plays a role in defense against numerous pathogens and is recruited to sites of

179 c GRP78 activity may be a potential strategy against obesity and associated comorbidities.

180 vity than other anti-gp120 MAbs in screening against one of two gp120s and against DS-SOSIP, which mi

181 The mutant has no growth defect, arguing against ongoing restriction of its own DNA.

182 ign principles to ensure robust vesiculation against opposing forces like membrane tension.

183 roves endothelial function and is protective against oscillatory shear stress-induced endothelial dys

184 Polyclonal antibodies were generated against OTC molecule (anti-OTC), purified and the qualit

185 atural flavonoids at protecting neural cells against oxidative stress and is capable of rescuing dama

186 nes and rhIL-26 lacked antimicrobial potency against P. acnes.

187 ucous layer provides a critical host defense against pathogen exposure and epithelial injury, yet lit

188 roducts have served as powerful therapeutics against pathogenic bacteria since the golden age of anti

189 digestive tract is the first line of defense against pathogens and damage.

190 ntrol of cell-signaling pathways and defense against pathogens and whose imbalance leads to pathologi

191 s a form of cell death important in defenses against pathogens that can also result in a potent and s

192 In agreement with a role in defending against pathogens, XBAT35.2 interacts with defense-relat

193 mune system and define first-line of defence against pathogens.

194 treatment with a blocking antibody directed against PD-1.

195 h OLE exerted similar antiglycative capacity against pentosidine and Nepsilon-carboxyethyl-lysine, al

196 unosorbent assays with monoclonal antibodies against PfLDH or PfIDEh showed detection limits of 100-2

197 toes elicited a potent melanization response against Plasmodium berghei ookinetes and exhibited signi

198 deficiency is believed to confer protection against Plasmodium falciparum malaria, but the precise n

199 is is an important immune effector mechanism against Plasmodium falciparum-infected erythrocytes (IE)

200 as a critical regulator of genomic stability against platinum-induced mutagenesis.

201 l line NK-92 became TCR positive and reacted against pMHC target.

202 as more rapid development of countermeasures against potential biothreats.

203 for effective pre-invasive immune responses against powdery mildews.

204 s were transfected with small inhibitor RNAs against PPP1R1, injected into the tail veins of immune-c

205 ted antibody-dependent cellular cytotoxicity against PRAME+HLA-A2+ leukemia cells and was therapeutic

206 We suggest that protection against predators conferred by their high toxicity might

207 onal species pools to help buffer ecosystems against predicted increases in environmental variability

208 We also detected CD8(+) T cell reactivity against predicted neoepitopes after isolation of cells f

209 lium is crucial in the host's innate defence against primary alphaherpesvirus infections.

210 (between frameworks) and criterion validity (against QALYs from the National Institute for Health and

211 We designed our strategy to select against re-targeting the 'knockout-first' allele and ide

212 therapy, the use of small organic molecules against receptor tyrosine kinases (RTKs) has been shown

213 rimary NPHV infection, horses were protected against rechallenge with the homologous as well as a dis

214 es but not control samples showed reactivity against recombinantly expressed N-terminal LRP2 fragment

215 bs whose epitope being within residues 44-65 against reconstituted HDL particles, indicating that the

216 tion and anti-HEV antibodies seem to protect against reinfection, its pathogenesis is not well establ

217 host signaling axis they activate to protect against respiratory infection.

218 ophages are a critical first line of defense against respiratory pathogens.

219 cient recipients failed to afford protection against respiratory reinfection with influenza virus.

220 Vaccines and prophylactic antibodies against respiratory syncytial virus (RSV) are in develop

221 on (F) protein to confer bivalent protection against RSV and HPIV3.

222 e describe how F-specific antibodies protect against RSV and why specifically targeting prefusion F c

223 st or positive allosteric modulator activity against RXFP1.

224 l effectiveness of Ty21a-AR-Ss in protecting against S. sonnei shigellosis and typhoid fever, as comp

225 a significant increase in NK cell activation against said target cells.

226 higher antimutagenic activity than zerumbone against Salmonella tester strains.

227 There was no effect against serotype 3.

228 tent and long-acting antiretroviral response against several laboratory-adapted and clinical HIV-1 is

229 approved method used to protect individuals against several pathogens and toxins.

230 d respirators (OR = 0.12; 95% CI: 0.06-0.26) against severe acute respiratory syndrome (SARS).

231 eus and Streptococcus pyogenes and protected against staphylococcal alpha-toxin-induced keratinocyte

232 ipid mixture had direct bactericidal effects against Staphylococcus aureus and Streptococcus pyogenes

233 amine has also been shown to be prophylactic against stress-induced depressive-like behavior in mice.

234 tA mutant strain elicits protective immunity against subsequent infection with wild-type bacteria.

235 received showed evidence of being protective against symptoms of the three mental illnesses studied,

236 w SES in Choco serves as a protective factor against T2D.

237 therapy aimed at manipulating host immunity against TB.

238 Vector carrying shRNA against TGF-beta, though did not inhibit HBV replication

239 ustrated by comparing the C-C bond in ethane against that in bis(diamantane), and dispersion stabiliz

240 s balancing the need to seek food and energy against the accompanying dangers of injury and predation

241 benralizumab, a monoclonal antibody directed against the alpha subunit of the interleukin-5 receptor

242 Helicobacter pylori confers protection against the anaphylaxis associated with ovalbumin and pe

243 hic impact on life, agriculture and property.Against the backdrop of a declining monsoon, the number

244 ibited, and a significant protection in mice against the bacterial challenge was observed at a microm

245 radiotherapy, and was confirmed by the test against the critical HR being more than 2.03 (p=0.003 fo

246 nduced oxidative bursts to prime crop plants against the deleterious effects of environmental stresse

247 mide, showed that CerS6-deficiency protected against the development of colitis.

248 a farm environment has been shown to protect against the development of inflammatory diseases, such a

249 a dual activator of NRF2 and HSF1, protects against the development of UV irradiation-mediated cutan

250 reservoir induces spontaneous DNA migration against the direction of flow.

251 arization show opposite variation tendencies against the doping level, and the sample with x = 0.3 ha

252 n-modified peptide (RK-10-Biotin) was tested against the FDA-approved SP263 clone on biopsied patient

253 we identify DNA repair factors that protect against the genotoxicity of ICLs generated by trioxsalen

254 T cell-depleted mice displayed no protection against the heterosubtypic virus challenge after immuniz

255 the unicellular parasite Trypanosoma brucei against the host immune system is a dense coat that comp

256 s, with the potential to amplify or mitigate against the increased flood risk caused by sea-level ris

257 s revealed increased autoaggression activity against the liver.

258 cally significant vaccine efficacy was found against the non-laboratory-confirmed clinical outcomes.

259 The protective effect of TPO against the primary oxidation of these refined oils was

260 on debts, or the progress of climate change) against the rate at which spending appreciates in value

261 Where symbionts provided protection against the same natural enemy, the level of protection

262 sed the MIC of rifampicin and clarithromycin against the same pathogens from 16 to 32 mug/mL to nanom

263 eduction in differential functional activity against the sensitive and Pgp overexpressing resistant c

264 These findings warn against the simplistic use of spatial analysis on availa

265 (D recommendation) The USPSTF recommends against the use of estrogen alone for the primary preven

266 There is also evidence of herd protection against the vaccine-specific and cross-protective types

267 tion (HSCT), posing as a significant barrier against the widespread use of HSCTs as a curative modali

268 s known to be at the disposal of prokaryotes against their viruses.

269 y luciferase complementation assay to screen against this chimeric receptor.

270 ATP-competitive inhibitors against this complex have been recently advanced in the

271 e two of the most effective management tools against this pest.

272 creening of molecules with therapeutic value against this toxic neuropathy.

273 egy is a target for therapeutic intervention against this viral disease.

274 ently stimulates endogenous immune responses against those antigens.

275 These cells have reduced cytotoxicity against tumor cells, and mice with NFATc1-deficient T ce

276 -positive cancer cells, but were ineffective against tumor vasculature.

277 ave shown significant activity, particularly against tumors driven by the estrogen receptor (ER).

278 their synergy with adaptive immune responses against tumors, and discuss recent studies highlighting

279 The immune system can mount T cell responses against tumors; however, the antigen specificities of tu

280 -term immune memory and decreased activities against tumour-cell subpopulations with low targeting re

281 Inhibition of miR-204 protects against tunicamycin-induced vascular/endothelial ER stre

282 nd representative of the protective response against type III GBS polysaccharide.

283 , heme oxygenase-1 in the skin and protected against UVB-induced oxidative stress, inflammation and p

284 It is presently uncertain whether antibodies against V3 can interfere with the induction of NAbs, but

285 This compound efficiently protects cells against various toxins and pathogens including viruses,

286 Bevacizumab, a monoclonal antibody directed against VEGF, improves outcomes when added to platinum-b

287 Bevacizumab, a monoclonal antibody against VEGF, improves the proportion of patients respon

288 ecimens were immunostained using an antibody against VEGF.

289 and triggered by ligand functions to protect against viral challenge, which probably accounts for its

290 l targets in the modulation of host defences against viral pathogens.

291 of infected flies, confer passive protection against virus challenge in naive animals.

292 provided strong, T cell-dependent protection against viruses or tumors.

293 l in the development of blood stage vaccines against vivax malaria.

294 measured binding affinity for four synbodies against VLPs from multiple GI and GII genotypes and foun

295 acute and chronic stress and were protected against weight loss associated with chronic stress.

296 t potentially actionable genetic alterations against which targeted therapies have been effective in

297 ve breast margin assessment (IMA) techniques against which the performance of emerging IMA technologi

298 cotiana benthamiana as a system to study NHR against Z. tritici.

299 Vaccine candidates against ZIKV are coming online, but immunological tools

300 lls are likely to be important in protection against zoonotic infection with FeLV.IMPORTANCE Domestic