ライフサイエンスコーパス: age-matched

1 controls with no CUP diagnosis were sex and age matched 10:1 to patients with CUP.

2 Control subjects were 55 age-matched (+/- 2 years) girls with no clinical hyperan

3 Four age-matched (48.5 +/- 4.7 years) lean (BMI <25 kg/m(2))

4 Twenty-seven patients were age matched (49-65 years old) for comparison of retinal

5 Thirty-six women were 1 : 1 age-matched across three groups: AN, HC, and overweight/

6 functionally integrated, expanded cohort of age-matched adult-born DGCs.

7 e density in the amygdala between ASD and TD age-matched adults (>/=18 years old).

8 ransfer of fetal hematopoietic cells between age-matched allogeneic murine fetuses, cell-extrinsic si

9 es of 26 patients with RPD and 21 eyes of 16 age-matched AMD patients with drusen were included.

10 ents with ALS, 75 carers and 83 sex-matched, age-matched and education-matched controls participated.

11 ompared for 32 subjects with left TLE and 36 age-matched and gender-matched controls along the left a

12 Twenty-nine patients with MND and 22 age-matched and gender-matched healthy controls were ass

13 Age-matched and sex-frequency-matched community controls

14 Healthy age-matched and sex-matched controls were also recruited

15 dementia or mild cognitive impairment and 20 age-matched and sex-matched healthy controls.

16 elerated decrease in muscle T2 compared with age-matched B10-mdx muscles.

17 t GIO animal model in 12 weeks old CD1 mice, age matched C57BL/6J mice were not susceptible to the bo

18 Age-matched, cage-dwelling, Veh- and Tam-treated mice wi

19 ch parents of 99 unilateral and 56 bilateral age-matched case-control pairs were interviewed by telep

20 ectronic health record to conduct a sex- and age-matched case-control study to evaluate the associati

21 this hospital-based surveillance and nested age-matched case-control study, we did laboratory invest

22 and fibroblasts from IPF lungs compared with age-matched cells from normal lungs include defective au

23 re patients (premature group); and full-term age-matched children (full-term group).

24 ion (at-risk, n = 27; 8-14 years of age) and age-matched children of parents with no lifetime history

25 CONV, reaching levels equivalent to those in age-matched, chronically infected individuals.

26 r AD, but had no history of seizures, and 19 age-matched, cognitively normal controls.

27 characteristics of patients with DAPs to an age-matched cohort with nondecremental accessory pathway

28 defined severe and very severe pneumonia and age-matched community controls.

29 dhood and adolescent cancer survivors and an age-matched comparison group.

30 nonimmunologic failed grafts; along with 43 age-matched control eyes) were imaged using high-definit

31 A sex- and age-matched control group was included for both.

32 plasma samples from neonatal PA patients and age-matched control individuals identified a set of diff

33 symptomatic patients with HD and 15 healthy age-matched control individuals underwent positron emiss

34 In addition, 49 age-matched control individuals with noninflammatory der

35 atients with Parkinson's disease, 31 elderly age-matched control participants and 20 young healthy vo

36 d ADHD (87 persisters, 23 remitters) and 169 age-matched control participants were compared on cognit

37 with relapsing-remitting MS and 30 healthy, age-matched control participants were enrolled in the st

38 diopathic PD without dementia and 15 healthy age-matched control participants without PD.

39 In 34 MS patients and 17 age-matched control participants, 7-T quantitative T2* m

40 on the Mini-Mental State Examination and 16 age-matched control participants.

41 and word recognition scores in comparison to age-matched control patients, spanning every decade of l

42 21 years of age) with retrograde DAPs and an age-matched control population with nondecremental acces

43 in patient-derived dermal fibroblasts versus age-matched control samples.

44 H activity in dermal fibroblasts compared to age-matched control samples.

45 n SCORAD score, 55 and 65, respectively) and age-matched control subjects (15 children and 27 adults)

46 in young healthy control subjects (n = 12), age-matched control subjects (n = 10), and patients with

47 es (4-10 years of age at study entry) and 69 age-matched control subjects at two time points spaced 1

48 reated with methotrexate and eight untreated age-matched control subjects by using Wilcoxon rank-sum

49 dy, 16 patients with early AD and 17 healthy age-matched control subjects underwent dynamic contrast

50 ith newly diagnosed Parkinson disease and 20 age-matched control subjects were recruited.

51 elf-reported GBCA exposure), and 11 sex- and age-matched control subjects without a history of GBCA e

52 e = 7.88 years; 27 females) as compared with age-matched control subjects without diabetes (n = 26; m

53 ed with the contralateral asymptomatic limb, age-matched control subjects, and young control subjects

54 dividuals with ALS and 35 gender-matched and age-matched control subjects.

55 s with Behcet disease and 32 healthy sex and age-matched control subjects.

56 i)CD127(lo) Tregs from children with T1D and age-matched control subjects.

57 on potential, when compared to wild type and aged matched control 22Rv1 cells.

58 als affected with knee osteoarthritis and 52 age matched controls and tested for association with kne

59 cantly higher than the frequency expected in age-matched controls (6%).

60 AS (67+/-15 years, 20 female) and 10 healthy age-matched controls (69+/-5 years, 5 female) were prosp

61 radic AD (n = 54) in comparison with healthy age-matched controls (HS; n = 24).

62 emale patients), and 16 eyes from 12 healthy age-matched controls (mean [SD] age, 57.9 [8.1] years; 8

63 were significantly lower than those for the age-matched controls (median = 0.54 right eye and 0.53 l

64 ) for RSV infection, and healthy noninfected age-matched controls (n = 18).

65 ents with Alzheimer disease (AD, n = 14) and age-matched controls (n = 30).

66 es (n = 16 and 28, respectively) relative to age-matched controls (n = 30).

67 , nonswimming athletes (n = 38) and sex- and age-matched controls (n = 50).

68 0 years or more (Medalists, n = 26) and from age-matched controls (n = 7).

69 2 asymptomatic mutation carriers (psALS), 12 age-matched controls and affected patients with ALS.

70 of VMA in eyes affected by AMD compared with age-matched controls and no difference in the rate of de

71 red with 2 historical populations of normal, age-matched controls and with contralateral eyes in indi

72 preterm without perinatal brain injury, and age-matched controls born at full term using [18F]-DOPA

73 r fluid collected from glaucoma patients and age-matched controls followed by functional pathway and

74 Patients were eligible for inclusion as age-matched controls if they were treated for lymphoma,

75 als with chronic incomplete cervical SCI and age-matched controls needed to suppress (NOGO) or initia

76 Fourteen PFC patients and 20 healthy, age-matched controls performed a working memory task whe

77 ions of interest identified in comparison to age-matched controls showed significant differences betw

78 ed seventeen DED patients and 67 gender- and age-matched controls were enrolled.

79 udy, children with a suspected HEA and their age-matched controls were evaluated in 9 countries, usin

80 rmation of mutation in the BEST1 gene and 20 age-matched controls were included.

81 hmatics, 74 younger asthma patients, and 114 age-matched controls were recruited.

82 Age-matched controls were residents of Muzaffarpur who w

83 used to train nine patients with PD and nine age-matched controls with multidirectional waist-pull pe

84 elevated in advanced AMD cases compared with age-matched controls with no AMD.

85 n = 15) and bilateral cataract (n = 15), and age-matched controls with no ocular abnormality (n = 15)

86 Seventy-seven age-matched controls with normal cognitive function also

87 abetic patients, and 16 eyes from 12 healthy age-matched controls, all at the New England Eye Center

88 mparison with eyes with nonexudative AMD and age-matched controls, and to evaluate prospectively the

89 tional study included 40 OSA patients and 45 age-matched controls, consecutively and prospectively se

90 ory B-cells from patients with cirrhosis and age-matched controls, ex vivo and activation-induced sen

91 rminal fields were 1.4x and 1.6x larger than age-matched controls, respectively.

92 ) in the basal forebrain of DLBD, but not in age-matched controls, suggests endo-lysosome rupture is

93 oural variant frontotemporal dementia and 22 age-matched controls, to assess how decision-making beha

94 Glaucomatous TM tissue is stiffer than age-matched controls, which may be due to alterations in

95 altered functional connectivity compared to age-matched controls.

96 onstrated increased mtDNA damage relative to age-matched controls.

97 igenetic age than their untreated, wild-type age-matched controls.

98 was increased by 1- to 4-fold, compared with age-matched controls.

99 ary progressive aphasia variant, compared to age-matched controls.

100 b- microparticles) in COPD patients, but not age-matched controls.

101 l and cardiac muscles as compared with their age-matched controls.

102 rting from postmortem DLPFC of 36 PDS and 26 age-matched controls.

103 bers developed thinner axons and myelin than age-matched controls.

104 ers, both of which groups were compared with age-matched controls.

105 ith a history of failed quit attempts and 18 age-matched controls.

106 developing cardiovascular disease (CVD) than age-matched controls.

107 nd neurons from three SPG11 patients and two age-matched controls.

108 fferent from those in muscle specimens of 10 age-matched controls.

109 s fulfilling PAF diagnostic criteria, and 15 age-matched controls.

110 ional study from a cohort of AD patients and age-matched controls.

111 atients post mortem was observed compared to age-matched controls.

112 ic regions of rats with tinnitus compared to age-matched controls.

113 available for 234 patients with PCa and 711 age-matched controls.

114 ta of post-mortem PD brains as compared with age-matched controls.

115 arrow was obtained from diseased animals and age-matched controls.

116 al hazards model were compared with those of age-matched controls.

117 tting among 22 patients with glaucoma and 11 age-matched controls.

118 ut ablation outcomes are similar to those of age-matched controls.

119 ith 43 moderate-to-severe AD patients and 30 age-matched controls.

120 mmation in 59 patients with cirrhosis and 59 age-matched controls.

121 uals and in sporadic AD subjects compared to age-matched controls.

122 , 3 males with slowly-progressing CKD, and 2 age-matched controls.

123 was reduced by 50% or more when compared to age-matched controls.

124 ng transplant patients (n = 18), and healthy aged-matched controls (n = 10).

125 lung transplant patients (n=18) and healthy aged-matched controls (n=10).

126 , and sacrificed at 60 days in parallel with age-matched CV mdr2(-/-) mice.

127 r remission prediction in three independent, age-matched data sets, respectively.

128 was sampled from 104 AAAD+ patients and 103 age-matched donors.

129 15)O-H2O (370 MBq) scans were obtained in 35 age-matched elderly subjects, including 10 probable AD,

130 ical corticobasal degeneration cases and six age-matched end-stage corticobasal degeneration cases we

131 ceptible to SARS-CoV infection compared with age-matched females.

132 in the booster-dose group, compared with the age-matched first-dose group.

133 - and post-GBCA exposure comparisons) and 57 age-matched GBCA-naive control subjects.

134 ggressive NHL from 2000 to 2010 and sex- and age-matched general-population controls.

135 (18)F-FDG dynamic PET scans were obtained in age-matched groups comprising AD patients (n = 8), patie

136 60.5+/-13.3 years) with MacTel as well as an age-matched healthy control group (42 eyes of 25 subject

137 Participants with OCD (n = 20) and age-matched healthy control individuals (n = 20) underwe

138 Twelve age-matched healthy control subjects had 11C-Pittsburgh

139 Thirty-seven patients with asthma and 17 age-matched healthy control subjects underwent spirometr

140 6 years with a confirmed diagnosis of CF and age-matched healthy control subjects were enrolled at th

141 3 patients with adrenomyeloneuropathy and 12 age-matched healthy control subjects who underwent quant

142 ents with first-episode psychosis as well as age-matched healthy control subjects with magnetic reson

143 n motor axons were compared with those in 30 age-matched healthy control subjects.

144 arynx samples from 20 infants with CF and 45 age-matched healthy control subjects.

145 m disorder, 26 with bipolar disorder) and 50 age-matched healthy control subjects.

146 in cementum density ( P = 0.009) compared to age-matched healthy control teeth.

147 D3 than patients with either mild sepsis or age-matched healthy controls (15.7 vs 49.5 vs 66.5 nmol/

148 In this study, seventeen patients and age-matched healthy controls (HC) performed a variant of

149 with probable Alzheimer disease (AD) and 10 age-matched healthy controls (HCs), the second was 31 su

150 des of disease severity) along with sex- and age-matched healthy controls (n = 9).

151 ages of transitional and mature B cells than age-matched healthy controls (P<0.001).

152 haracterized PHEX mutations or with sex- and age-matched healthy controls and cultured up to 24 d usi

153 children with AD, ADHD, comorbid AD/ADHD and age-matched healthy controls and to investigate aspects

154 en patients with coronary artery disease and age-matched healthy controls revealed that mtDNA damage

155 duals with sporadic Parkinson's disease, and age-matched healthy controls seen from November, 2012, t

156 ubjects (disease duration </=5 years) and 24 age-matched healthy controls underwent 7 T T2*-weighted

157 rns with complex CHD prior to surgery and 30 age-matched healthy controls using brain MRI.

158 0.05) in women suffering rUTIs, compared to age-matched healthy controls with concentrations further

159 s of peripheral blood mononuclear cells from age-matched healthy controls with West Eurasian or Afric

160 rty-five males (30 athletes and 15 sedentary age-matched healthy controls) underwent comprehensive ca

161 eople with sporadic Parkinson's disease, and age-matched healthy controls, all aged 18 years or older

162 and decreased amyloid pathology compared to age-matched healthy controls, confirming our experimenta

163 ansporters in groups of patients with PD and age-matched healthy controls.

164 cell disease, respectively, as well as in 41 age-matched healthy controls.

165 four with logopenic variant), as well as 28 age-matched healthy controls.

166 Nineteen patients with sepsis and 19 age-matched healthy controls.

167 people with sporadic Parkinson's disease and age-matched healthy controls.

168 ) and CD21(low) (9/41) B cells compared with age-matched healthy donors (1/33 and 2/33, respectively)

169 ut retinopathy, and 44.4 (8.3) microL/min in age-matched healthy eyes.

170 The controls included age-matched healthy full-term children.

171 h various neurodegenerative diseases and 202 age-matched healthy individuals.

172 limbs and were compared with MR images in 12 age-matched healthy individuals.

173 ated markers (CD119/CD120b) as compared with age-matched healthy individuals.

174 patients with DR and 34 control eyes from 27 age-matched healthy participants.

175 itis, or necrotizing myopathy, and 0/20 (0%) age-matched healthy subjects had large granular lymphocy

176 Macular cube OCT data from age-matched healthy subjects were provided by the OCT re

177 making in 36 female patients with AN and 36 age-matched healthy volunteers (12-24 years).

178 performed from February to May 2015) and 19 age-matched healthy volunteers at a primary care center

179 rompton & Harefield NHS Foundation Trust and age-matched healthy volunteers using advertising and exi

180 e-surgical TLE patients (7 MRI-negative) and age-matched healthy volunteers were scanned at 7T.

181 The results were compared with data from age-matched healthy volunteers.

182 had been clinically stable for 6 months, and age-matched healthy volunteers.

183 Colon biopsies from 32 women with IBS and 15 age-matched healthy women (controls) were mounted in Uss

184 subjects with food allergy (n = 100) than in aged-matched healthy controls (n = 112) (P = 0.004).

185 nts' microbiomes were then compared with 154 age-matched, healthy Dutch infants' microbiomes, assumed

186 tiation (median, 12 mo) and compared with 19 age-matched HIV-uninfected individuals using flow cytome

187 104 cases were compared with 104 age-matched hospital controls.

188 -/-) double knockout mice were compared with age-matched hyperglycemic ApoE(-/-) littermates.

189 s included in the study, together with 2,412 age-matched individuals from the general population.

190 Up to 20 sex- and age-matched individuals per patient were identified in t

191 (63% of Kcne3(-/-) mice >/=10-mo-old vs. 0% age-matched Kcne3(+/+) littermates).

192 haracteristics that were similar to those of age-matched kidney donors, the 15-year projections of th

193 et-induced obese (DIO) mice as compared with age-matched lean controls.

194 ther fed a high-fat diet for 12-14 weeks, or age-matched lean controls.

195 ared with 4.6 +/- 1.4 mL/cm(3) of a sex- and age-matched MAB.

196 h ASD (n = 50) and from typically developing age-matched male control subjects (n = 16) were stimulat

197 study in 100 male patients with acne and 100 age-matched male controls without acne from a dermatolog

198 7 antipsychotic free) were compared with 18 age-matched male healthy control subjects (HCs).

199 rculating metabolites across a 24-h day in 3 age-matched, male groups-lean, overweight/obese (OW/OB),

200 All studies were conducted in age-matched, male mice consuming alcohol-containing liqu

201 dence in premenopausal females compared with age-matched males.

202 These changes were not evident in age-matched males.

203 tween measured preoperative axial length and age-matched mean axial length (prior studies) was calcul

204 ses diagnosed from 2009 to 2012, and 192,838 age-matched men free of prostate cancer.

205 Thirty-two age-matched men with no evidence of hair loss were recru

206 Unlike age-matched men, premenopausal women benefit from cardio

207 Using Ixodes scapularis ticks and age-matched mice purchased from two independent commerci

208 Six age-matched naive goats served as uninfected controls.

209 Age-matched nBmp2NLS(tm) and wild type mice were analyze

210 d samples of 83 participants with ASD and 76 age-matched neurotypical peers.

211 ll/islet mass was examined among 10 cases of age-matched non-diabetic male subjects in relation to BM

212 rt had a Braak staging III-IV compared to an age-matched non-epilepsy control group from the literatu

213 Samples from age-matched non-neuropathic individuals were used as con

214 In 17 patients and 10 age-matched non-smoking control subjects we examined bra

215 l cortex of aged transgenic (Tg) mice and of age-matched non-transgenic littermate controls (Ctrl) mi

216 of 12-months-old APP(E693Q) as compared with age-matched non-transgenic littermates, and western blot

217 Age-matched nonasthmatic control subjects were included

218 te, 18.6% black, and 12.0% Hispanic) and 285 age-matched nonburned controls (mean [SD] age, 2.4 [1.3]

219 Age-matched nonburned reference groups were studied to d

220 t cancer from community oncology clinics and age-matched noncancer controls completed the Functional

221 hs after treatment with chemotherapy than do age-matched noncancer controls.

222 .1] years; 64.7% female) and 204 eyes of 102 age-matched noncarriers (mean [SD] age, 67.1 [11.8] year

223 arriers of identified variants (n = 177) and age-matched noncarriers (n = 157).

224 ), and 18 with proliferative DR (PDR)-and 64 age-matched nondiabetic control eyes.

225 children with established PD (PD group), and age-matched nonuremic controls (n=6/group).

226 efore and after LAIV vaccination and from 16 age-matched, nonvaccinated controls.

227 pathology nondemented controls compared with age-matched normal controls.

228 RNFL compared to the fellow eyes as well as age-matched normal eyes on OCT.

229 less in deprivational amblyopic eyes than in age-matched normal eyes, but there was no significant di

230 superior and nasal quadrants as compared to age-matched normal eyes.

231 al subbasal nerve density when compared with age-matched normal mice.

232 A total of 30 perimetric glaucoma and 30 age-matched normal participants were included.

233 biopsies from nine patients and nine healthy age-matched normal subjects, using immunomorphology and

234 gn hepatobiliary disorders (BHD) and 20 from age-matched "normal controls"(NC).

235 rogeroid features are indistinguishable from age-matched, normal controls.

236 4% of probes in the DS samples compared with age-matched normals.

237 (probability map that compared patients with aged-matched normative database) and thickness measureme

238 in HTN (n = 14; 56 +/- 2 years) compared to age-matched normotensive adults (NTN; n = 14; 55 +/- 2 y

239 ctivity in human glaucomatous AH compared to age-matched normotensive control AH.

240 (mean +/- SEM: 179 +/- 11% increase) than in age-matched normotensive Wistar-Kyoto rats (114 +/- 9% i

241 In a large cohort of age-matched older adults ranging from cognitively normal

242 Age-matched outpatients with/without cirrhosis underwent

243 Age-matched, overweight males consumed 9 d of a high-fat

244 ents; response rate, 68.9% [of these, 15,981 age-matched participants were drawn]).

245 l cortex using the Golgi-Cox technique in 12 age-matched pathology-free controls, 8 controls with AD

246 30 ONA subjects, and 30 mild-to-moderate LA age-matched patients participated in a cross-sectional s

247 30 ONA subjects, and 30 mild-to-moderate LA age-matched patients participated in a cross-sectional s

248 -febrile illness (control group 1; n=98) and age-matched patients with acute Zika virus disease and n

249 ic variant of primary progressive aphasia, 6 age-matched patients with AD, and 6 control subjects und

250 s with HB at three treatment stages, 30 from age-matched patients with benign hepatobiliary disorders

251 In comparison, 2/15 (14%) age-matched patients with dermatomyositis, polymyositis,

252 onism treated with MR antagonists and 41 853 age-matched patients with essential hypertension from th

253 ophageal squamous cell cancer and 9 sex- and age-matched patients with functional dyspepsia.

254 of specific mRNAs between colon tissues from age-matched patients with ulcerative colitis (n=10) vs w

255 wing the death of their spouse compared with age-matched peers who had also lost their spouse and who

256 I patients <50 years versus 216 930 sex- and age-matched people from the general population.

257 Aged-matched rats were used for immunohistochemical dete

258 elf-reported diabetes in FH subjects than in age-matched relatives without FH.

259 mni athletes (N=33, aged 34-71 years) and an age-matched sample of comparison participants (N=18) wer

260 .36%) by 3 years of follow-up, whereas in an age-matched sample of Ontario women (n = 92,700) without

261 ere later analysed by quantitative RT-PCR in age-matched sedentary rats.

262 Wild-type littermates (age matched) served as controls.

263 Controls were age-matched, sex-matched, and residence-matched patients

264 prospectively in a twin cohort (n = 30) and age-matched singletons (n = 14) born at National Taiwan

265 ) scans in the BPES sample and in a group of age-matched subjects imaged for nonorbital diseases.

266 s (a) greater in young ASD cases compared to age-matched TD controls (<18 years old) and (b) decrease

267 ual processes in young children with ASD and age-matched TD controls.

268 g to the Global Acne Grading System and were age matched to 100 male controls without acne.

269 group; and patients with Alzheimer's disease age-matched to the CAA group.

270 two independent cohorts of healthy controls age-matched to the CAA group; and patients with Alzheime

271 WA-D using genetic testing; healthy controls age-matched to the HCHWA-D group; patients with probable

272 older (age 30 years; 30M/18F) patients were age-matched to younger and older healthy volunteer group

273 and SCD groups were divided into a sex- and age-matched training set (n = 130) and an independent pr

274 oteins (MBGs) in 65 children with ASD and 65 age-matched typically developing (TD) children were comp

275 and 12 and 24 months in all patients and in age-matched unaffected siblings.

276 g antiretroviral therapy (ART; cases) and 95 age-matched uninfected controls.

277 re virtually indistinguishable from those in age-matched unwounded skin.

278 or LT with FKBP1b substantially outperformed age-matched vector controls and performed similarly to e

279 tment with ranolazine and were compared with age-matched vehicle-treated animals.

280 Age-matched virgin (i.e., nulliparous) and multiparous m

281 cutive adults with tuberculosis and sex- and age-matched volunteers were included in a case-control s

282 -deficient microbiota were comparable to the age-matched, well-nourished profile, the protein-restric

283 T) or 40% (in the case of A586V) compared to age-matched wild type controls.

284 fat to lean mass ratio at advanced ages than age-matched wild type mice.

285 well as isoproterenol-challenged heart than age-matched wild type mice.

286 ion, and serum biochemistry, and compared to age-matched wild-type (Cdc73(+/+) and Cdc73(+/+)/PTH-Cre

287 less apoptotic beta-cells compared with the age-matched wild-type (WT) controls.

288 iabetic cardiomyopathy (DCM), male db/db and age-matched wild-type (WT) mice were given sulforaphane

289 mRNA microarray profiling in comparison with age-matched wild-type controls (WTy/WTo).

290 in 6- to 8-mo-old TASTPM transgenic mice and age-matched wild-type controls using the (64)Cu bis(thio

291 at 5- and 12-month old, compared with their age-matched wild-type controls.

292 rom male and female late-stage R6/2 mice and age-matched wild-type controls.

293 PLP-SYN and age-matched wild-type mice were treated for a period of

294 he MZ in aged bumble mice were distinct from age-matched wild-type MZ B cells.

295 Relative to age-matched wild-type, (18)F-GE180 SUVR was slightly ele

296 igher in young SHRs (122 +/- 5 mmHg) than in age-matched Wistar-Kyoto rats (99 +/- 5 mmHg), but lower

297 Consecutive 46 PAH males and 94 females were age matched with a representative sample of 1168 males a

298 iation, 26 years +/- 6) and 30 normal-weight age-matched women (control group).

299 ad significantly lower podocyte density than age-matched WT and Tg-G0 mice had, a difference that was

300 approximately 60%; P < 0.05), as compared to age-matched WT mice.