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1 tious agent that consists of a misfolded and aggregated form of a sialoglycoprotein called prion prot
4 interest because the accumulation of toxic, aggregated forms of Abeta, from small oligomers to very
6 ue to the interactions of the chaperone with aggregated forms of Abeta42 rather than the monomeric fo
8 rons in vivo, although the precise role each aggregated form of alpha-synuclein plays in neurotoxicit
9 aggregation than the cytosolic protein, and aggregated forms of alpha-syn are also secreted from cel
10 Spatz disease, implicating a crucial role of aggregated forms of alpha-synuclein in the pathogenesis.
11 ence of "Lewy body" inclusions enriched with aggregated forms of alpha-synuclein, a presynaptic prote
15 owed strong binding to various fragmented or aggregated forms of CII in Western blots, as well as str
17 protected against toxicity resulting from an aggregating form of green fluorescent protein (GFP) in a
19 marked by their common pathologic feature of aggregates formed of hyperphosphorylated tau protein, wh
20 with age-related accumulation of soluble and aggregated forms of N-terminal mutant htt fragments, sug
22 ficulties in detecting and quantifying small aggregated forms of polyQ, and because all possible stru
23 physico-chemical properties of the different aggregated forms of proteins, and of their interactions
27 tion of neuritic amyloid plaques composed of aggregated forms of the beta-amyloid peptide (Abeta).
28 eurodegenerative disorders that present with aggregated forms of the cellular prion protein (PrPC), w
29 rate of thermal energy dissipation from the aggregated forms of the complex and, possibly, thermal e
34 utations in the sod1 gene, and misfolded and aggregated forms of wild-type SOD1 are found in both spo
35 ence for the hallmarks of amyloid fibrils in aggregated forms of WT and mutant myocilin localized to
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