ライフサイエンスコーパス: aglycone

1 the diet containing 0.015% genistein (as the aglycone).

2 ety attached via a carbon-carbon bond to the aglycone.

3 hosphate, and Teg12 bound to the teicoplanin aglycone.

4 s further elaborated to a protected candidin aglycone.

5 ntical to the naturally derived landomycin A aglycone.

6 cis relationship between the epoxide and the aglycone.

7 phosphodiester linkage to a phosphoglyceride aglycone.

8 -1), for an alternate substrate, teicoplanin aglycone.

9 teicoplanin molecule and the other with the aglycone.

10 the fact that they release the same aromatic aglycone.

11 -->GalNAc linked via an alpha-linkage to the aglycone.

12 of the inherent base lability of the parent aglycone.

13 red lactone macrolides based on spiramycin's aglycone.

14 ete decomposition/transformation of terpenyl aglycone.

15 bled the convergent total synthesis of G-CSF aglycone.

16 clover contains mostly easily absorbed free aglycones.

17 , digoxin, digitoxin, and gitoxin with their aglycones.

18 nferring biological activities to its parent aglycones.

19 gut requires deconjugation of glucosides to aglycones.

20 d aglycone equivalents, primarily (95.8%) as aglycones.

21 benzimidazole and 2-quino-2-benzimidazole as aglycones.

22 nst bone loss may be enhanced for isoflavone aglycones.

23 he enzymes that biosynthesize the glycolipid aglycones.

24 within tissues and cells than do polyphenol aglycones.

25 avone composition in mediating conversion to aglycones.

26 leomycin A(2) (4), as well as the respective aglycones.

27 es), although occasionally they are found as aglycones.

28 of a single class of compounds, the flavonol aglycones.

29 s on beta-D-xylosides containing hydrophobic aglycones.

30 cosides were, in most cases, equipotent with aglycones.

31 with isorhamnetin and quercetin as the major aglycones.

32 e potentials were higher than those of their aglycones.

33 glucosides, 72.9% malonylglucosides and 1.2% aglycones.

34 sidase and convert glycosidic isoflavones in aglycones.

35 through hydrolysis to give the corresponding aglycones.

36 new signal shifted 4-6 ppm upfield from the aglycone 2-fluoro-4-nitrophenol (OFPNP).

37 The aglycone, 3-hydroxybenzo[a]pyrene, was metabolized to 3-

38 DHPEA-EDA (6) and oleuropein (1), oleuropein aglycone (4) and hydroxytyrosol ORACFL values was undert

39 The enantiomer of the bicyclic lomaiviticin aglycone A core was prepared via a two-directional, dive

40 '-desmethylepipodophyllotoxin (the etoposide aglycone), a naturally occurring lignan that is the imme

41 inds TDP in the interdomain cleft, while the aglycone acceptor binds in a deep crevice in the N-termi

42 cquisition of MS3 product ion spectra of the aglycone adducts [BH2]+.

43 rgely unknown whether structural features of aglycone affect the extent of sulfation, sulfation patte

44 le extract was readily converted to apigenin aglycone after combination with almond, flax seed, or ch

45 the identities of four glucosides and seven aglycones, among them vanillin (5.7/100 g), 4-hydroxyben

46 strate that gossypin (and not gossypetin, an aglycone analog) inhibited NF-kappaB activation induced

47 the closely related (-)-deacetoxy-oleuropein aglycone and a series of related analogues for structure

48 The ECA(CYC) molecules lacked an aglycone and contained four trisaccharide repeat units t

49 The major phenolic acids, some flavonoid aglycone and glycosides were identified in leaves by hig

50 They exist in planta as both the aglycone and glycosyl conjugates.

51 Microbial GNPs consist of aglycone and glycosyl structure groups in which the suga

52 The aglycone and sugar moieties of the cytotoxic drug are es

53 Using the teicoplanin aglycone and the 3 sulfotransferases found in one of the

54 d hydrolysis was highly dependent on type of aglycone and the conditions.

55 erein a convergent total synthesis of GM-CSF aglycone and two homogeneous glycoforms.

56 des to acetylglycosides, beta-glycosides and aglycones and a significant reduction in the activity of

57 Flavonols were analysed as aglycones and anthocyanins as authentic compounds using

58 spectrometry (APCI-MS/MS) of citrus limonoid aglycones and electrospray ionization tandem mass spectr

59 The four limonoid aglycones and four limonoid glucosides (LG, OG, NAG, and

60 at 100 degrees C did not degrade the lignan aglycones and glycosides in dry foods.

61 roasting temperatures caused degradation of aglycones and glycosides.

62 red clover extract (RCE) rich in isoflavone aglycones and probiotics to concomitantly promote uptake

63 en Vibrio cholerae also encodes rhabduscin's aglycone, and bacterial cell-coated immunosuppressants c

64 LIF-mono, and DLIF-bis, corresponding to the aglycone, and the aglycone with one and two sugars, resp

65 (194) forming stacking interactions with the aglycone, and the hydrogen bond between the His(195) nit

66 ce a better product, due to lower amounts of aglycones, and higher protein nutritional quality than h

67 tyl glycosides were about twice as active as aglycones, and the peracetyl glycosides were, in most ca

68 ed a novel group of unique anthocyanins with aglycones (anthocyanidins) at 449, 419 and 433 Da.

69 In contrast to apoptolidin A, the aglycones apoptolidinone A and D were shown to be noncyt

70 In contrast to apoptolidin A, the aglycone (apoptolidinone) shows no cytotoxicity (>10 muM

71 These aglycones are most likely derived from beta-amyrin, a pr

72 xyloside derivatives linked to a hydrophobic aglycone as substrates and/or inhibitors.

73 eroids 19-hydroxysarmentogenin and trewianin aglycone as well as to the assembly of the panogenin cor

74 tion by various cardiac glycosides and their aglycones at different pH values using shark Na,K-ATPase

75 soflavone conjugates may serve as sources of aglycones at specific target tissues and may have bioact

76 ha-hederin and one for delta-hederin) on the aglycone backbone, hederagenin.

77 olic acids, their derivatives, and flavonoid aglycones based on their molecular masses and fragmentat

78 here was a conversion of isoflavone forms to aglycones, being higher in heat-processed samples.

79 rate complexes of Dhr1 show that the mode of aglycone binding differs from that previously observed i

80 bserved in the surface loops surrounding the aglycone binding site, and these are likely to strongly

81 259), Phe(261), and Ser(462), located in the aglycone-binding site of S. bicolor Dhr1, are crucial fo

82 p378, Phe466, and Ala467) are located in the aglycone-binding site of ZmGlu1 and form the basis of ag

83 bstrate imposed by steric impediments at the aglycone-binding site.

84 The associated aglycone biosynthetic genes of the GNP genotype then cla

85 MPK, an effect also seen with phloretin (the aglycone breakdown product of phlorizin), but not to any

86 ng (ABMP) employing a physiologic library of aglycones built from glycosides isolated from grape.

87 on of chloroeremomycin from the heptapeptide aglycone by the sequential actions of the three enzymes.

88 ing benzoic acids, cinnamic acids, flavonoid aglycones, C- and O-glycosides, coumarins, and lignans)

89 P and attachment of the neutral sugar to the aglycone can occur in either order.

90 In this study, we show that aglycones can switch not only the type of GAG chains, bu

91 Daunomycinone (daunomycin aglycone), carminomycin, 13-dihydrocarminomycin, idarubi

92 om cocrystals of enzyme-substrate and enzyme-aglycone complexes have shown that five amino acid resid

93 The total aglycone content in black soymilk was enriched by 67.14+

94 oflavone composition can be used to modulate aglycone content in soy food products.

95 rees C for 25min, the daidzein and genistein aglycone contents were maintained, the glycitein and bet

96 type of deoxysugar residues attached to the aglycone core.

97 from a TDP donor to the beta-OHTyr-6 of the aglycone cosubstrate.

98 in enantioselective free energy between the aglycone CSP and the teicoplanin CSP was between 0.3 and

99 resolution factors 2-5 times higher with the aglycone CSP.

100 were better separated on the teicoplanin and aglycone CSPs, respectively.

101 25 mug/d) given either RCE (60 mg isoflavone aglycones/d and probiotics) or a masked placebo [control

102 ldehydic forms of oleuropein and ligstroside aglycones (DAFOA and DAFLA), indicating a more active pa

103 Concentrations of 12 isoflavone isomers, 3 aglycones (daidzein, genistein, and glycitein), and 9 gl

104 the simultaneous determination of isoflavone aglycones (daidzein, glycitein and genistein), their cor

105 ds, pigment content and deacetoxy oleuropein aglycone (DAOA) content and didn't affect the sensory ch

106 A Hydrogen bond mediated aglycone delivery (HAD) method was applied to the synthe

107 uring negative ion APCI analysis of limonoid aglycones, depending on the mobile-phase modifier used.

108 The position of the glucose on the aglycone determines how SA is stored, further metabolize

109 acid hydrolysis the area of released terpene aglycone did not exceed 1.3% of total peak area indicati

110 s of daily supplementation with 80 or 120 mg aglycone equivalent soy hypocotyl isoflavones plus calci

111 Genistein content (aglycone equivalent) of the soy isolate diets were 15, 1

112 gle soy meal containing 64.8 mg isoflavonoid aglycone equivalents (95% as glucosides).

113 nistein compounds were measured expressed as aglycone equivalents per 100g of fresh fruit flesh.

114 8 g) + isoflavone tablets (105 mg isoflavone aglycone equivalents), soy protein + placebo tablets, co

115 provided approximately 100 mg isoflavones/d (aglycone equivalents).

116 ls (90 mg epicatechin) + 100 mg isoflavones (aglycone equivalents)/d] or matched placebo.

117 yme contained 36.7% of ingested isoflavonoid aglycone equivalents, primarily (95.8%) as aglycones.

118 e blood and tissues are, in general, neither aglycones (except for green tea catechins) nor the same

119 Aglycone flavonols accumulated at the hypocotyl-root tra

120 In young Landsberg erecta seedlings, aglycone flavonols accumulated developmentally in three

121 Aglycone flavonols are thought to modulate auxin transpo

122 ffective for developing a flavone-rich, high aglycone food ingredient from celery.

123 the chemopreventive compound diosmin and its aglycone form, diosmetin, on the carcinogen activation p

124 elds of polyketide products, but only in the aglycone form.

125 dent on whether isoflavone treatments are in aglycone form; we conclude that beneficial effects again

126 tection was shown to be able to observe both aglycone formation and further reactions in isolated fra

127 y encoding three early enzymes of triterpene aglycone formation: squalene synthase (SS), squalene epo

128 olinone and maleimide functionalities of the aglycones formed are all derived from dioxygen.

129 Both aglycone forms and glycosides of monolignols, lignin oli

130 enzymatic conversion of isoflavones to their aglycone forms.

131 and subsequent Heck cyclization delivers the aglycone framework in an overall 12 steps.

132 uman oral microbiota to produce wine odorant aglycones from odourless grape glycosidic aroma precurso

133 for at least one sugar residue linked to the aglycone (-genin).

134 d daidzein are found in blood and tissues as aglycones, glucuronides, and sulfates.

135 vonoids through combinatorial enumeration of aglycone, glycosyl, and acyl subunits.

136 s characterized for activity either with the aglycones (GtfB, E) or the glucosylated derivatives (Gtf

137 s, and subsequent GC-MS determination of the aglycones, highlighted that the majority of norisoprenoi

138 ucosyldisaccharide chain on residue 4 of the aglycone; however, the characterization of GtfA and glyc

139 For the synthesis of the aglycones, improved synthetic avenues to substituted cou

140 correlations between the monosaccharide and aglycone in the intact natural product.

141 sugars and glycosyltransferases compete for aglycone in these cells.

142 r results enable production of the etoposide aglycone in tobacco and circumvent the need for cultivat

143 nversion of isoflavone glycosides into their aglycones in black soymilk.

144 conversion of beta-glucoside isoflavones to aglycones in soymilk processing and to evaluate their th

145 en isolating studies that provide isoflavone aglycones in their treatment arm, the average effect was

146 of o-diphenols (hydroxytyrosol or oleuropein aglycone) in olive oil led to a lower oxidation rate und

147 drug molecules bind to the duplex, with the aglycones intercalated between the CpG or TpG steps and

148 erting diverse, fully synthetic polyphenolic aglycones into the corresponding glycosides in a whole-c

149 onversion of beta-glucosides into isoflavone aglycones involved soaking the soybeans at 5 degrees C f

150 rosporine by streptomycetes, assembly of the aglycones involves a complex set of oxidative condensati

151 e tetrahydro-beta-carboline of strictosidine aglycone is converted into akuammicine, a Strychnos alka

152 involved in elaboration of the rebeccamycin aglycone is encoded by rebO, located at the left-hand re

153 The binding site of the aglycone is located in the N-terminal half of the protei

154 The binding site of the aglycone is located in the N-terminal half of the protei

155 It is clearly established that the aglycone is responsible for the enantioseparation of ami

156 amounts of isoflavones (Soy- group) or 80 mg aglycone isoflavones (Soy+ group).

157 kefir-fermented soymilk is a good source of aglycone isoflavones and phenolics, since the content of

158 ms and the storage process did not alter the aglycone isoflavones and total phenolic contents.

159 The content of aglycone isoflavones increased 2-fold, and the total phe

160 responding increase in the concentrations of aglycone isoflavones, with the magnitude of these change

161 ion can potentially occur in vivo to produce aglycone, it occurs only at certain sites.

162 1)), and an unnatural substrate, teicoplanin aglycone (k(cat) = 20 min(-1)).

163 ating both its natural substrate, vancomycin aglycone (k(cat) = 60 min(-1)), and an unnatural substra

164 Overall formation of aglycones K252c and arcyriaflavin A from their biosynthe

165 tophan to the staurosporine and rebeccamycin aglycones, K252c and 1,11-dichloroarcyriaflavin A.

166 Sequence analysis indicates that the aglycone kijanolide is formed by the combined action of

167 cs having a similar structure of 16-membered aglycone lactone ring.

168 ABMP of aglycone libraries provides a versatile tool to uncover

169 agmentation patterns of four citrus limonoid aglycones (limonin, nomilin, obacunone, and deacetylnomi

170 Increasing the aglycone lipophilicity of a series of polysulfated oligo

171 e concentrations should be normalized to the aglycone mass (or an isoflavonoid equivalent) rather tha

172 igate the first two reactions in teicoplanin aglycone maturation catalyzed by the enzymes OxyBtei and

173 milar broad specificities for both sugar and aglycone moieties and exhibit nearly identical pH depend

174 tion of the primers and the structure of the aglycone moieties can affect the composition of the newl

175 pecificity, beta-glucosides to release toxic aglycone moieties.

176 in type, structure and composition of their aglycone moiety and oligosaccharide chains.

177 + NH3]+ of limonoid glucosides produced the aglycone moiety corresponding to each glucoside.

178 The tight binding of the aglycone moiety of dhurrin promotes the stabilization of

179 lucosides, with specificity depending on the aglycone moiety, the type of sugar and the linkage betwe

180 bic interactions dominate the binding of the aglycone moiety.

181 activated dissociation (CAD) of the limonoid aglycone molecular ions in negative ion APCI analysis, f

182 and applied a suite of difluoromethylphenyl aglycone, N-halogenated glycosylamine, and 2-deoxy-2-flu

183 them to be 2- to 3-fold more potent than the aglycone natural product K-252c.

184 say method considers 13 flavanones including aglycones, neohesperidosides, rutinosides and 3-hydroxy-

185 The aglycone novobiocic acid, obtained from selective degrad

186 and extended to deacylated anthocyanins and aglycones, obtained, respectively, by alkaline and acid

187 macrocyclic skeleton of rimocidinolide, the aglycone of (+)-rimocidin (1), has been achieved in conv

188 proposed structure (2) of landomycinone, the aglycone of landomycin A, has been synthesized and shown

189 Functionalization of 16-membered aglycone of spiramycin with the use of intramolecular ca

190 6-Deoxyerythronolide B, the macrocyclic aglycone of the antibiotic erythromycin, is synthesized

191 or the biosynthesis of 6-dEB (1), the parent aglycone of the broad spectrum macrolide antibiotic eryt

192 We report the synthesis of an aglycone of the surugatoxin family.

193 ent, enantioselective total synthesis of the aglycone of the tetrocarcins, (+)-tetronolide, is descri

194 the thioamide derivates 6a-1, including the aglycone of thiosangivamycin (6m), were good inhibitors

195 toyocamycin (4m) furnished the corresponding aglycone of thiosangivamycin (6m).

196 A similar transformation of the aglycone of toyocamycin (4m) furnished the corresponding

197 -hydroxyl group of tylactone, the polyketide aglycone of tylosin (Ty).

198 g interactions between the base pair and the aglycone of WP401.

199 extraction the benzoic acid derivatives and aglycones of flavonoids showed lower recovery (70-80%).

200 ed to the apoplast, we hypothesized that the aglycones of these compounds are made within the cell.

201 The aglycones of vicine and convicine, divicine and isourami

202 The "aglycone" of pluraflavin A (2) has been synthesized.

203 These enzymes act on the free peptide aglycone or intermediates bound to the nonribosomal pept

204 irrespective of whether they are ingested as aglycones or glycoside conjugates.

205 ost all such studies, cells are treated with aglycones or polyphenol-rich extracts (derived from plan

206 ivity was determined toward two prototypical aglycones, p-nitrophenol and estrone, in intact and digi

207 lightly differently oriented relative to the aglycone part if compared to that of spiramycin (1).

208 tic teicoplanin, a molecule consisting of an aglycone peptide "basket" with three attached carbohydra

209 he methoxy group at the C(4) position on the aglycone portion also appears to add potency and selecti

210 nded wedge-shaped spirocyclic molecule whose aglycone portion is an enantiomer of DDI, which mimics t

211 n as the key step in combining the sugar and aglycone portions.

212 s the formation of tylactone (1), the parent aglycone precursor of the macrolide antibiotic tylosin.

213 olide and 10-deoxymethynolide, the macrolide aglycone precursors of the antibiotics picromycin and me

214 bonolide (2), the parent 12- and 14-membered aglycone precursors of the macrolide antibiotics methymy

215 ncosamine to the beta-OH-Tyr6 residue of the aglycone, preferentially after GtfB action, to generate

216 and 1,6-conjugate addition at the spiramycin aglycone, proceeds with the inversion of absolute config

217 t, further degradation and transformation of aglycones produce more or less active compounds, dependi

218 This study investigated the stability of the aglycones produced by hydrolysis with beta-glucosidase.

219 validated the expression system, endogenous aglycone production was prevented by deletion of the pol

220 own converts chromopyrrolic acid into three aglycone products, K252c, arcyriaflavin A, and 7-hydroxy

221 mportantly, the obtained sample presented an aglycone proportion superior to the reported by other me

222 uring positive ion APCI analysis of limonoid aglycones, protonated molecular ion, [M + H]+, or adduct

223 observed at 919.88 m/z, which represents the aglycone [prymagly+2H](2+) backbone structure common to

224 Many aglycones reached or exceeded their odor thresholds, enr

225 binding site of ZmGlu1 and form the basis of aglycone recognition and binding, hence substrate specif

226 ing site of S. bicolor Dhr1, are crucial for aglycone recognition and binding.

227 cipally by the glycone binding site, whereas aglycone recognition is highly plastic.

228 Odorant aglycones released in the culture mediums were isolated

229 tasting, by retronasal perception of odorant aglycones released in-mouth.

230 The volatile aglycones released varied depending on the substrate spe

231 are almost twice the molecular weight of the aglycones; reported isoflavone concentrations should be

232 erythromycin and pikromycin 14-membered ring aglycones, respectively.

233 and dTDP-L-daunosamine, and the monoglycosyl aglycone, rhodosaminyl aklavinone.

234 ng interactions with both xylopyranoside and aglycone rings.

235 are glycosides of triterpenoid or steroidal aglycones (sapogenins).

236 to crosslinking between the side chains, the aglycone scaffold displays substantial flexibility, impo

237 ncosamine is the terminal sugar added to the aglycone scaffold in chloroeremomycin, a member of the v

238 atoms on each of two indole moieties of the aglycone scaffold.

239 Isoflavone aglycones show higher bioavailability than their glycosi

240 osides of at least five different triterpene aglycones: soyasapogenol B, soyasapogenol E, medicagenic

241 t saponins based on at least five triterpene aglycones; soyasapogenols B and E, medicagenic acid, hed

242 ties that may play a role in conferring such aglycone specificities were predicted by structural mode

243 Quantification of aglycones spiked with (13)C(3)-labeled internal standard

244 erol, hydroxytyrosol, tyrosol and oleuropein aglycone) spiked in Purified Olive Oil (POO) as the lipi

245 The proportion of aglycones, ss-glucosides, and acetyl and malonyl glucosi

246 is a wedge-shaped spirocyclic molecule whose aglycone structure closely resembles that of the natural

247 compounds were glycosides of four different aglycone structures, of which akebonoic acid and gypsoge

248 represent a specificity determinant at this aglycone subsite.

249 e accommodated in the glycone as well as the aglycone subsites.

250 Importantly, the aglycone substrate demonstrates a flattened conformation

251 bind to the N-terminal domain such that the aglycone substrate's reactive hydroxyl group hydrogen bo

252 phoadenosine 5'-phosphate and desulfo-A47934 aglycone substrate.

253 can be efficiently attached to a 16-membered aglycone substrate.

254 GRs can also occur between carbohydrates and aglycones, such as the phenolic compounds present in dai

255 NovM displays activity with variant coumarin aglycones, suggesting it may be a promiscuous catalyst f

256 The unusual structure of the spinosyn aglycone suggests an intriguing biosynthetic pathway for

257 er activity for free terpenoic and benzenoic aglycones than the yeast glycosidases.

258 substrate TDP-L-fucose are also added to the aglycone, the disaccharide and low levels of a fully rec

259 ble to show formation and degradation of the aglycones, the proposed method allows monitoring of the

260 ration of the derivatives of the secoiridoid aglycones; the effect of the temperature on the oxidored

261 nsferase AknS transfers L-rhodosamine to the aglycone to initiate construction of the side-chain tris

262 es examined hydrolyzed LacdiNAc from the TMR aglycone to various degrees, whereas they were less acti

263 library of click-xylosides that have various aglycones to decipher the mechanism of GAG biosynthesis

264 ubation with beta-glycosidase, percentage of aglycone (total aglycone/total isoflavones) in SIM isofl

265 a-glycosidase, percentage of aglycone (total aglycone/total isoflavones) in SIM isoflavone extracts i

266 eck for all studies providing isoflavones as aglycones.Twenty-six RCTs (n = 2652) were included in th

267 esulting strain was fed with the 16-membered aglycone tylactone, the normal TylM2 substrate.

268 GtfB efficiently glucosylates vancomycin aglycone using UDP-glucose as the glycosyl donor to form

269 ymethyl-2',7'-dioxane moiety attached to the aglycone via a carbon-carbon bond.

270 arbohydrate units covalently attached to the aglycone via an additional carbon-carbon bond.

271 Resolution of the aglycone via stereospecific glycosylation with an enanti

272 Desosamine is added to the parent aglycone via the action of a glycosyltransferase that ut

273 y generated cinnamic acid from coumaric acid aglycone was detected in fermented plant material combin

274 The enzyme was inactive when the aglycone was methanol but shows activity against the gly

275 The sugar units were removed and the aglycone was purified.

276 earing a 1,4,5-trisubstituted-1,2,3-triazole aglycone was synthesized using a straightforward click/e

277 The extraction of aglycones was better at higher ratios, but leveled off b

278 The biosynthesis of the APG aglycones was investigated by examination of the enzymat

279 The highest concentration of free aglycones was observed following hydrolysis with Pektopo

280 ol glycosides and increase in the respective aglycones was observed, attributed to enzymatic hydrolys

281 paper, two other coumarin glycosides and one aglycone were confirmed.

282 ydrolysis with Rapidase AR2000, the released aglycones were analysed by GC-MS.

283 However, the recoveries of tested aglycones were below 10%.

284 A range of UGT aglycones were capable of modulating glucuronidation in

285 Aglycones were detected only after soaking and their con

286 The synthesized compounds and their aglycones were evaluated to determine their minimal bact

287 (PNQ) antibiotic lactoquinomycin and related aglycones were found to be selective inhibitors of the s

288 extraction, and dansylation of unconjugated aglycones were tested and optimized.

289 nd luteolin derivatives, in contrast to free aglycones, were not cytotoxic against human lymphocytes

290 lysis 85-91% of total peak areas was terpene aglycone, whereas for acid hydrolysis the area of releas

291 e vesicles preferentially take up monolignol aglycones, whereas the vacuolar vesicles are more specif

292 lts in a significant rise of the odoriferous aglycones which are direct determinants of the aroma.

293 framework and stereochemical features of an aglycone while simultaneously establishing the site of g

294 -bis, corresponding to the aglycone, and the aglycone with one and two sugars, respectively.

295 eloped a synthetic platform to prepare G-CSF aglycone with the goal of enabling access to native and

296 in the small intestine and appear to absorb aglycones with an efficiency comparable with that of con

297 highly dependent on the sugars linked to the aglycone, with alpha-hederin showing a greater ability t