ライフサイエンスコーパス: agonist-induced

1 Notably, agonist-induced 3-phosphorylated phosphoinositide produc

2 effect of these compounds on CB(1) receptor agonist-induced [(35)S]GTPgammaS binding, inhibition, an

3 These data showed that agonist-induced 5-HT(1A)R internalization does exist in

4 Thrombin, a G protein-coupled receptor agonist, induced a biphasic expression of cyclin D1 in p

5 rolongs the AP by 25% and abolishes the GPCR agonist-induced acceleration of the AP repolarization.

6 d for re-priming, had only a minor effect on agonist-induced accumulation of nonphosphorylated protei

7 we show that cSrc inhibition also blocks the agonist-induced acrosome reaction and that this inhibiti

8 increasing K(+) concentrations inhibited the agonist-induced acrosome reaction as well as the increas

9 cyte-derived dendritic cells (MoDCs) and TLR agonist-induced activation assessed by cytokine producti

10 R4.60A resulted in a total ablation of agonist-induced activation in both the beta-arrestin tra

11 Agonist-induced activation of D(1) receptors promoted en

12 ation of ERKs requires Raf, alpha-adrenergic agonist-induced activation of ERKs does not require it.

13 These data support the novel concept that agonist-induced activation of M3R dimers requires a conf

14 AZD8529 potentiated agonist-induced activation of mGluR2 in the membrane-bin

15 depletion from the PM was achieved either by agonist-induced activation of phospholipase C beta or wi

16 n vitro, M8-B blocked cold-induced and TRPM8-agonist-induced activation of rat, human, and murine TRP

17 hat these residues have an important role in agonist-induced activation of receptors.

18 Agonist-induced activation of Rho GTPase signaling leads

19 l assays, we identified residues involved in agonist-induced activation of TAS2R10, and investigated

20 boxy-terminal portion of NTS responsible for agonist-induced activation of the receptor.

21 effects of dopamine-2 receptor (D2R) and its agonist-induced activation on trafficking of Ca(V)2.2 is

22 ecent structures of the muOR in inactive and agonist-induced active states (Huang et al., ref.

23 37 selectively inhibited the agonist-induced activity of PPARbeta/delta, enhanced tra

24 These data point towards an agonist-induced adaptive response by KOR, the dynamics o

25 rthermia-susceptible muscle, we investigated agonist-induced adenosine formation in lymphocytes as an

26 tail of MOPr was identified as a mediator of agonist-induced affinity changes in MOPr.

27 PKC downstream of 12-LOX inhibition rescued agonist-induced aggregation and integrin activation.

28 nd dynamin dependent and could be modeled as agonist-induced aggregation of transiently expressed GFP

29 he association of a PEAR1 variant with multi-agonist-induced aggregation.

30 pathway for ASMCs with respect to sustaining agonist-induced airway contraction and the underlying Ca

31 ay that mediates both swelling-activated and agonist-induced amino acid release in brain glial cells.

32 These LXR agonists induced an increased matrix metalloproteinase-1

33 Our data identify an agonist-induced and Ca(2)(+)-dependent protein-protein i

34 Here we show that HKL blocks agonist-induced and pressure overload-mediated, cardiac

35 RXR agonist-induced antileukocyte adhesive effects seemed to

36 Moreover, KOR agonist-induced antinociceptive tolerance observed in vi

37 for 'self' are either eliminated through TCR-agonist-induced apoptosis (negative selection) or restra

38 ptor substates in favor of the active state, agonist-induced arrestin recruitment is accompanied by a

39 cells with ASM activated by IL-33 increased agonist-induced ASM contraction, and in vivo IL-33 induc

40 pathways mediating this Ca(2+) influx during agonist-induced ASMC contraction are not well defined.

41 hese studies show that photolysis but not by agonists induced astrocytic Ca(2+) signaling triggers gl

42 y IDO1 activity or treating mice with a GCN2 agonist induced autophagy and protected mice from nephri

43 We show that BQCA potentiates agonist-induced beta-arrestin recruitment to M1 mAChRs.

44 palmitoylation of Cys-265 is negligible, but agonist-induced beta2AR activation results in enhanced S

45 Other agonists induced borderline-normal aggregation.

46 Our findings reveal how PAF-R agonists induced by chemotherapy treatment can promote t

47 p38 Mapk activation but also plays a role in agonist-induced C-terminal and linker region phosphoryla

48 1 residues resulted in 58+/-3.8% decrease in agonist-induced C3aR phosphorylation there was no change

49 Here we investigated the involvement of agonist-induced Ca(2+) entry and STIM1 and Orai1 protein

50 The decline in extracellular K(+) evoked by agonist-induced Ca(2+) in Bergmann glia transiently incr

51 However, resting Ca(2+) levels, agonist-induced Ca(2+) increases, store-operated Ca(2+)

52 Agonist-induced Ca(2+) oscillations are accompanied by o

53 As a result, agonist-induced Ca(2+) oscillations are critically depen

54 Abstract Agonist-induced Ca(2+) oscillations in many cell types a

55 the roles of CB2R agonist, GW405833 (GW) in agonist-induced Ca(2+) oscillations in pancreatic acinar

56 through InsP3Rs and consequent reduction of agonist-induced Ca(2+) oscillations in SMCs.

57 Agonist-induced Ca(2+) oscillations underlie this contra

58 affect the ability of BH4-Bcl-2 to suppress agonist-induced Ca(2+) release in the cytosol or to prev

59 dimers were fully functional as indicated by agonist-induced Ca(2+) release.

60 mined by the temporal and spatial aspects of agonist-induced Ca(2+) signals.

61 SOCE and agonist-induced [Ca2+](i) increase are significantly blu

62 s also impaired, as indicated by reduced RyR agonist-induced calcium release from the ER and RyR-medi

63 hereas p11 overexpression potentiates mGluR5 agonist-induced calcium responses, overexpression of mGl

64 Conversely, PDE4D ablation enhanced agonist-induced cAMP accumulation in the bulk cytosol as

65 ceptor, the concentration-response curve for agonist-induced cAMP accumulation was shifted to the lef

66 ive allosteric modulation of the orthosteric agonist-induced cAMP accumulation, [(35)S]GTPgammaS bind

67 However, the molecular cascade coupling agonist-induced cannabinoid receptor activation to insul

68 The compounds modulated the hypertrophic agonist-induced cardiac gene expression.

69 importantly, overexpression of CIP repressed agonist-induced cardiomyocyte hypertrophy.

70 ct; it increases agonist binding, yet blocks agonist-induced CB1 signaling.

71 vated ARC neurons was assessed by monitoring agonist-induced cellular activity via calcium imaging in

72 raft plasma membrane markers) to analyze the agonist-induced changes in compartmentalization of AT(1)

73 sensors serve the dual purpose of detecting agonist-induced changes in GPCR-G protein interactions,

74 ired-end tag sequencing of P300, we observed agonist-induced changes in long-range chromatin interact

75 that of the nAChR and GLIC, does not undergo agonist-induced channel gating, although it does not exh

76 ound alpha-Btx molecules required to prevent agonist-induced channel opening remains unknown.

77 ls, SOCE mediated by ORAI1 was necessary for agonist-induced chloride secretion and activation of the

78 intra- and interdimer cross-links such that agonist-induced closure of the LBD "clamshells" is trans

79 h lacks the last 101 residues, revealed that agonist-induced confinement was abolished and that the a

80 ubject to various interpretations, including agonist-induced conformational change versus selective s

81 t GalphaiAGS3 and GalphaiAGS4 directly sense agonist-induced conformational changes in the receptor,

82 rings from Iqgap1-/- mice generated greater agonist-induced contractile force, even after removal of

83 ase, Ca(2+) influx, PKC and ROCK in alpha(1)-agonist-induced contraction and phosphorylation of key p

84 A) receptors, plays a major role in alpha(1)-agonist-induced contraction of small resistance arteries

85 individuals with asthma exhibited increased agonist-induced contraction.

86 SAR218645 potentiated mGluR2 agonist-induced contralateral turning.

87 Here, c-Abl silencing inhibited the agonist-induced cortactin phosphorylation and the associ

88 hetic TLR7 and TLR9 agonists, as well as TLR agonist-induced costimulatory molecule expression and TN

89 e (ACh): agonist sensitivity (EC50), maximal agonist-induced current (Imax), and time constant (tau)

90 Therefore, the reduced agonist-induced currents are caused by the reduced numbe

91 glutamate delta-2 receptor (GluRdelta2), no agonist-induced currents are observed from GluRdelta1 re

92 us report that the mutation leads to reduced agonist-induced currents; in the cortical neurons studie

93 TLR agonist-induced cytokine production was measured in huma

94 The ontogeny of TLR8 agonist-induced cytokine responses was defined in rhesus

95 n autologous plasma; levels of alum- and TLR agonist-induced cytokines and costimulatory molecules we

96 Imaging and preclinical studies have shown agonist-induced D2R internalization can be imaged with p

97 duced confinement was abolished and that the agonist-induced decrease in diffusivity was reduced subs

98 IGF-1R, but protecting the receptor against agonist-induced degradation.

99 l membrane compartmentalization in selective agonist-induced degradation.

100 nses that were associated with impaired beta-agonist-induced denitrosylation of cardiac ryanodine rec

101 while the magnitude of DSI or CB(1) receptor agonist-induced depression of IPSCs was decreased in MAG

102 G protein-coupled receptor kinases (GRKs) in agonist-induced desensitization of the mu-opioid recepto

103 s lack the phosphorylation sites involved in agonist-induced desensitization of the other two subtype

104 nthol followed by its washout did not affect agonist-induced desensitization, suggesting that menthol

105 expression, activation, and internalization/agonist-induced desensitization.

106 Agonist-induced dimerization of TLR4 Toll/IL-1R (TIR) do

107 iated gene inactivation, exhibited defective agonist-induced down-regulation.

108 r of SL biosynthesis partially prevented CB2 agonist-induced effects on cell viability and motility.

109 es constitutive internalization, whereas the agonist-induced effects were imperceptible.

110 essed as an intrabody, it robustly inhibited agonist-induced endocytosis of a broad set of GPCRs with

111 alendronate treatment functionally reversed agonist-induced endogenous beta2AR loss as indicated by

112 f proteins represent a major pathway for the agonist-induced entry of calcium associated with the gen

113 ) binding, nuclear translocation of AHR, and agonist-induced enzyme activity also were determined and

114 x metalloprotease inhibitor, GM6001, blocked agonist induced Erk activation within seconds, strongly

115 Agonist-induced Erk phosphorylation was preceded by rapi

116 In contrast, it acts as an enhancer of agonist-induced ERK phosphorylation.

117 The agonist-induced exocytosis of WPB from BOECs and formati

118 of membrane fusion to control the extent of agonist-induced exocytosis.

119 t Galpha(13), but not Galpha(q/11), controls agonist-induced expression of hypertrophy-specific genes

120 onists in the VTA failed to affect mu opioid agonist-induced feeding elicited from the NACs, and corr

121 VTA or NACs differentially affects mu-opioid agonist-induced feeding elicited from the same site.

122 the VTA or NACs differentially affects GABA agonist-induced feeding elicited from the same site.

123 Intracerebroventricular injection of GPR17 agonists induced food intake, whereas administration of

124 agonist binding nonetheless antagonized the agonist-induced G-protein coupling to the CB1 receptor,

125 The decrease in the rate of agonist-induced GIRK conductance was receptor selective

126 Agonist-induced GPCR shedding from the ciliary surface m

127 endent fashion with SNPs in Hap -6A favoring agonist-induced GR binding.

128 tor (alpha = 16.55) and potent antagonism of agonist-induced GTPgammaS binding.

129 or G-protein association, thereby preventing agonist-induced guanine nucleotide exchange.

130 plays biased antagonism whereby it inhibits: agonist-induced guanosine 5'-O-(3-[(35)S]thio)triphospha

131 eater chromatin-GR binding with increased GR agonist-induced hAGT expression in liver and renal tissu

132 ngs may represent the first demonstration of agonist-induced heterodimerization of the H1R and H2R.

133 Depleting Intu blocked Smo agonist-induced Hh pathway activation, whereas the expre

134 10 (PtdIns 4,5-P2-binding peptide) inhibited agonist-induced HLHCGR and cAMP accumulation but not ARF

135 s of the ARF6 signaling pathway required for agonist-induced HLHCGR internalization.

136 Bile acids and a TGR5-selective agonist induced hyperexcitability of dorsal root ganglia

137 chostatin A (TSA), attenuated both load- and agonist-induced hypertrophic growth and abolished the as

138 rolactin response, but also blunted 5-HT(1A) agonist-induced hypothermia and increased 5-HT(2A) recep

139 Moreover, 5-HT(1A) receptor agonist-induced hypothermia is blunted and frontal corte

140 to internalize and bind GTP, blunting of the agonist-induced increase in cAMP production and decrease

141 agonist, HS024 (0.072nmol) blocked the MC4-R agonist-induced increased T(IBAT) in conscious, freely-m

142 d GIRK2 channel is necessary for the GABAB R agonist-induced infantile spasms phenotype in the Ts mou

143 e GIRK2 channel in Ts brain upon the GABAB R agonist-induced infantile spasms phenotype in the Ts mou

144 agonist tertiapin-Q also rescued the GABAB R agonist-induced infantile spasms phenotype in Ts mutants

145 esis that GIRK2 is necessary for the GABAB R agonist-induced infantile spasms phenotype in Ts.

146 mber of Kcnj6 in Ts mice rescued the GABAB R agonist-induced infantile spasms phenotype.

147 elet adhesiveness is critically dependent on agonist-induced inside-out activation of heterodimeric i

148 so enhanced islet GLP1R expression and GLP1R agonist-induced insulin secretion and glucose tolerance.

149 Although agonist-induced integrin alphaIIbbeta3 affinity regulati

150 TCR agonist-induced interaction between CRADD and BCL10 coin

151 Analysis in vitro demonstrated agonist induced internalization of both CXCR3 and other

152 ng cells in excess cholesterol increased the agonist-induced internalization and desensitization of O

153 ected by the three-residue mutation, with no agonist-induced internalization observed even in the pre

154 ew rationale to the differences in basal and agonist-induced internalization observed in cells.

155 Concomitantly, agonist-induced internalization of alpha2AAR is signific

156 The distribution and lack of agonist-induced internalization of D2 receptors on dopam

157 ells, we confirmed that AP-2 is required for agonist-induced internalization of endogenous PAR4.

158 face and facilitate resensitization, whereas agonist-induced internalization of PAR1 is critical for

159 Agonist-induced internalization, intracellular trafficki

160 PAR1 displays constitutive and agonist-induced internalization.

161 4 cell FPR1 was atypical in that it resisted agonist-induced internalization.

162 ker Rab7 and did not cluster with PICK1 upon agonist-induced internalization.

163 PAR1 displays both constitutive and agonist-induced internalization.

164 nodine receptor (RyR), plays a major role in agonist-induced intracellular calcium ([Ca(2+)]cyt) dyna

165 Model results show that agonist-induced intracellular calcium dynamics can be mo

166 eatment, GRKs, but not PKC, were involved in agonist-induced KOPR internalization.

167 Specifically, we demonstrate that the agonist-induced linker region phosphorylation of Smad2 a

168 Cocaine-induced and quinpirole (D2 receptor agonist)-induced locomotion was enhanced in rats that co

169 estigated the role of cingulin in control of agonist-induced lung EC permeability via interaction wit

170 hat central administration of senktide (NK3R agonist) induced luteinizing hormone (LH) secretion in p

171 Agonist-induced lysosome secretion ex vivo was also impa

172 enetic ablation of CB2 had any effect on CB2 agonist-induced macrophage chemotaxis.

173 i/o-coupled GPCR must be responsible for CB2 agonist-induced macrophage migration.

174 Thus, agonist-induced MAPK activation leads to Prdx6 phosphory

175 Particulate beta-glucan (a DECTIN-1 agonist) induced mast cell degranulation in mesenteric w

176 D5 receptors reversed priming, whereas D1/D5 agonists induced mechanical hypersensitivity exclusively

177 duce mGluR1 association with lipid rafts and agonist-induced, mGluR1-dependent activation of extracel

178 Rap1b to vesicular membranes that mimic the agonist-induced microenvironment.

179 H4-Bcl-XL peptide via electroporation limits agonist-induced mitochondrial Ca(2+) uptake and protects

180 role for GRK2 (and potentially also GRK3) in agonist-induced MOPr desensitization in the LC, but leav

181 to study the involvement of GRK2/3 in acute agonist-induced MOPr desensitization.

182 a Galphaibetagamma heterotrimer-biased CXCR4 agonist, induced more robust phosphorylation of Ser-346/

183 ysiological mechanism acting in concert with agonist-induced MYPT1 phosphorylation to inhibit MLCP ac

184 Furthermore, cues associated with a KOR agonist-induced negative affective state were assessed f

185 H23390 administration into the OFC plus GABA agonist-induced neural inactivation of the contralateral

186 sion of the M-current and prevents resultant agonist-induced neuronal hyperexcitability.

187 influx in skin and lung Arthus reactions and agonist-induced neutrophilia in the peritoneum, whereas

188 Importantly, agonist-induced NFAT activation is reduced in p65 null m

189 These mice exhibited lowered agonist-induced nitric oxide synthase (NOS) activity and

190 RXR agonists induced no beneficial effects in the E4FAD-HP i

191 e now demonstrate that Prdx6 is required for agonist-induced NOX2 activation in pulmonary microvascul

192 sidue is selective for only GPCR but not RTK agonist-induced nuclear export and proteolytic degradati

193 d symptom remission after 2-3 months of GnRH agonist-induced ovarian suppression (leuprolide) then re

194 he effects of gonadotropin-releasing hormone agonist-induced ovarian suppression on mood, sleep, sexu

195 0 muM; lungs, 20 muM; IC50, 29 nM) decreased agonist-induced oxidant generation.

196 Tymp deficiency also significantly decreased agonist-induced P-selectin expression.

197 ine the involvement of individual kinases in agonist-induced P-UAEC proliferation.

198 TLR2 or TLR4 agonist induced PAI-2 expression, which subsequently sta

199 lex-2 (AP-2), whereas AP-2 and epsin control agonist-induced PAR1 internalization.

200 sidues of the tyrosine-based motif disrupted agonist-induced PAR4 internalization.

201 ociated protein stathmin in the mediation of agonist-induced permeability in EC cultures and vascular

202 The role of TMEM16F in apoptosis- or agonist-induced phosphatidylserine (PS) exposure was stu

203 rmeability transition pore (mPTP) formation, agonist-induced phosphatidylserine exposure and alphaIIb

204 Increased PAR1 expression also enhanced agonist-induced phosphoinositide hydrolysis and endothel

205 o and in vivo studies also revealed a 5-HT1A agonist induced phosphorylation of FGFR1 and extracellul

206 s are known to play an essential role in the agonist-induced phosphorylation and desensitization of M

207 hly selective CK2 inhibitor, greatly reduced agonist-induced phosphorylation of beta-cell M3Rs, indic

208 hat receptor internalization is required for agonist-induced phosphorylation of extracellular signal-

209 Agonist-induced phosphorylation of G protein-coupled rec

210 Activation of the SHP-1 occurs on agonist-induced phosphorylation of SHP-1(Y536), triggeri

211 Agonist-induced phosphorylation of the parathyroid hormo

212 oss of negative signals from PKCalpha due to agonist-induced PKCalpha down-regulation and (b) positiv

213 for Hsp70/Hsc70 and Hsp90 in the control of agonist-induced PKCalpha processing.

214 The present study examines the impact of agonist-induced PKCbetaII activation on contractile func

215 Exposure of macrophages to inflammasome agonists induced PKR autophosphorylation.

216 inhibitor of Prdx6 PLA(2) activity, blocked agonist-induced PLA(2) activity and ROS generation in PM

217 ction of CIB1, and its ability to facilitate agonist-induced plasma membrane localisation of sphingos

218 e rs11202221 and rs6566765 associations with agonist-induced platelet aggregation are novel.

219 In this first GWAS of agonist-induced platelet aggregation in African American

220 n of IL-6 to the thrombocytosis, exaggerated agonist-induced platelet aggregation, and enhanced extra

221 A+ interacts with platelet TLR4 and promotes agonist-induced platelet aggregation.

222 Agonist-induced platelet surface activated glycoprotein

223 Moreover, agonist-induced PM translocation of Epac1 leads to disso

224 tic potentiation induced by oxytocin, Avpr1b agonist-induced potentiation of CA2 synapses relies on N

225 se HPV is usually studied in the presence of agonist-induced preconstriction ('pretone').

226 Sustained agonist-induced production of the second messengers InsP

227 osphorylated PKCalpha is a direct target for agonist-induced proteasomal degradation via an Hsp-regul

228 tation is recorded immediately downstream of agonist-induced receptor activation.

229 onformation at rest, and only GBR1 closes on agonist-induced receptor activation.

230 Agonist-induced receptor internalization followed a clat

231 r466 and Ser470 led to 40+/-1.3% decrease in agonist-induced receptor phosphorylation but this was as

232 ls stably expressing the M3-MR did not alter agonist-induced receptor phosphorylation or receptor int

233 work tested the hypothesis that lifetimes of agonist-induced receptor-arrestin clusters at the cell s

234 Agonist-induced receptor-G-protein coupling was of a tim

235 four residues to alanine partially decreased agonist-induced recruitment of arrestin3 without alterin

236 ed secretory compartment, which allows rapid agonist-induced redistribution of superoxide production

237 Basal and agonist-induced regulation of alpha2AAR-Galphai2YFP(C352

238 rthermore, overexpression of FBXO17 inhibits agonist-induced release of keratinocyte-derived cytokine

239 The Nfkb1(SSAA) mutation prevented the agonist-induced release of TPL-2 from its inhibitor p105

240 antagonist binding to the receptor, and the agonist-induced response.

241 Agonist-induced responses of Tyr-93 mutant alpha7-nAChRs

242 ependent potentiation and/or inactivation of agonist-induced responses.

243 Structural characterization of the PAF-R agonists induced revealed multiple oxidized glycerophosp

244 has been implicated in the amplification of agonist-induced Rho signaling, leading to increased vasc

245 These novel M(1) allosteric agonists induced robust electrophysiological effects in

246 Synthetic CB1R agonists induced robust LTD that was mimicked by the end

247 Agonist-induced rosette formation is blocked by pertussi

248 These results are consistent with agonist-induced rotation of the propeller-head domain of

249 icient in syntaxin-11 had a robust defect in agonist-induced secretion although their morphology, act

250 We show that agonist-induced sensitisation is independent of the agon

251 Agonist-induced sensitisation may provide an explanation

252 7 transmembrane biogenic amine receptors in agonist-induced signaling has not yet been clarified des

253 :09 is essential for the constitutive and/or agonist-induced signaling of the ghrelin receptor, GPR11

254 wn was performed, in human ASM cultures, and agonist-induced signaling was assessed.

255 romatic residue at position VI:09, unchanged agonist-induced signaling was observed upon Ala substitu

256 ken the hydrophobic core, showed significant agonist-induced signaling.

257 stration of CL-316,243, a selective beta3-AR agonist, induced significant increases in non-rapid-eye

258 We found that selective Avpr1b agonists induced significant potentiation of excitatory

259 GPCR agonist-induced silencing exhibited dependence on the ub

260 PAR4-agonist induced slower release of fewer molecules, where

261 e signal transduction process in response to agonist -induced smooth muscle contraction.

262 Finally, muscarinic agonist-induced smooth muscle contraction also exhibited

263 Our results demonstrate that agonist-induced SNO contributes to junctional membrane p

264 that low [Na(+)] is required to allow large agonist-induced structural changes in A2AR, and that pat

265 We also show that BQCA potentiates agonist-induced subcellular trafficking.

266 Cold- and beta3-adrenoceptor agonist-induced sympathetic activation leads to angiogen

267 Gemcitabine in combination with a CD40 agonist induced T-cell-dependent regression of subcutane

268 TLR agonist-induced TAG storage is a multifaceted process th

269 In all cases, agonist-induced tagged 5-HT(1A)R endocytosis was prevent

270 ntrast, sustained exposure (for 24 h) to all agonists induced tagged-5-HT(1A)R endocytosis in raphe s

271 We found that isolated ZP or alpha7 agonists induced the AR in sperm from WT but not alpha7-

272 Intranasal exposure with receptor agonists induced the release of IL-33 and subsequent eos

273 SYK inhibition in vivo represses beta-agonist-induced thermogenesis and oxygen consumption.

274 on induced by sodium arachidonate or ADP; 3) agonist-induced thromboxane production; and 4) NO produc

275 ivator, is phosphorylated in response to the agonist-induced TLR signaling.

276 induced traces, as well as the modulation of agonist-induced traces by anesthetic, either coapplied o

277 well, including both anesthetic-induced and agonist-induced traces, as well as the modulation of ago

278 ent of beta-arrestins and thereby affect the agonist-induced trafficking and agonist-dependent signal

279 Our results provide the first data on the agonist-induced trafficking of native GPR17 in oligodend

280 tty acid in synaptic membranes, enhances the agonist-induced transition to the desensitized state in

281 signaling to protein synthesis, deficits in agonist-induced translational control, protein synthesis

282 The TPR domain of AGS3 was required for agonist-induced translocation of AGS3 from the cell cort

283 Agonist-induced translocation of AGS3 to the GA altered

284 The agonist-induced translocation of AGS3 was reversed by th

285 This phosphorylation event inhibits agonist-induced translocation of Epac1 to the plasma mem

286 The molecular mechanisms underlying agonist-induced TRPV1 desensitization and/or tachyphylax

287 Agonist-induced turnover of palmitate occurs predominant

288 antiviral responses and was critical for TLR agonist-induced, type 1 IFN-dependent suppression of inf

289 onstrated that R753Q TLR2 exhibits deficient agonist-induced tyrosine phosphorylation, hetero-dimeriz

290 particle treatment prevented the cannabinoid agonist-induced up-regulation and enhanced 5-HT2A recept

291 identify the role of GRK5 in the cannabinoid agonist-induced up-regulation and enhanced activity of 5

292 Interestingly, we found that cannabinoid agonist-induced up-regulation of GRK5 involves CB2 recep

293 r ERK1/2 inhibitor prevented the cannabinoid agonist-induced up-regulation of GRK5.

294 lephrine (100 mumol/L), an alpha1 adrenergic agonist, induced upregulation of Nox4 (1.5-fold; P<0.05)

295 in B cells is correlated with impaired TLR7 agonist-induced upregulation of activation markers CD69

296 owed that adenosine or an ADORA2A or ADORA2B agonist induced V-ATPase translocation from vesicles to

297 ed the time-of-day variations in response to agonist-induced vasoconstriction, myosin phosphorylation

298 Expression of T210A Plk1 inhibited the agonist-induced vimentin phosphorylation at Ser-56 and c

299 The agonist-induced VPAC2 shedding is selective, as shown by

300 Sisley et al. reveal that GLP-1R agonist-induced weight loss requires GLP-1Rs in the CNS,