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1 timulating neuropeptides, neuropeptide Y and Agouti-related peptide.
3 hypothalamus (ARH) that contains orexigenic agouti-related peptide (AgRP) and anorexigenic pro-opiom
4 g-responsive hypothalamic neurons expressing agouti-related peptide (AgRP) and neuropeptide Y (Npy).
6 w leptin-sensing neuron population, multiple agouti-related peptide (AgRP) and pro-opiomelanocortin (
8 te time periods, and measured the density of Agouti-Related Peptide (AgRP) containing projections fro
9 ing view is that the orexigenic neuropeptide agouti-related peptide (AgRP) exerts the opposite action
11 ivate or inhibit ArcN NPY neurons expressing agouti-related peptide (AgRP) in mice, we have demonstra
14 M glucose concentrations, more inhibition of agouti-related peptide (AgRP) mRNA and AMP-activated pro
15 ortin (POMC) mRNA and increased hypothalamic agouti-related peptide (AGRP) mRNA and neuropeptide Y (N
16 d fasting on pro-opiomelanocortin (POMC) and agouti-related peptide (AgRP) mRNA levels in the hypotha
17 ine leptin inhibits neuropeptide Y (NPY) and agouti-related peptide (AgRP) neuronal activity, resulti
23 hysiologic regulation.SIGNIFICANCE STATEMENT Agouti-related peptide (AgRP) neurons play an important
26 ns, including proopiomelanocortin (POMC) and agouti-related peptide (AgRP) neurons, also release amin
27 ns, including proopiomelanocortin (POMC) and agouti-related peptide (AgRP) neurons, also release amin
28 ic proopiomelanocortin (POMC) and orexigenic agouti-related peptide (AgRP) neurons, electrophysiologi
30 eurons [e.g., proopiomelanocortin (POMC) and agouti-related peptide (AgRP) neurons], and as a result,
31 euron populations specified by expression of agouti-related peptide (AGRP) or pro-opiomelanocortin (P
34 conversely, administration of the antagonist Agouti-related peptide (Agrp) to wild-type mice enhanced
35 neurons expressing neuropeptide Y (NPY) and agouti-related peptide (AgRP) via GABA-dependent signali
36 gnaling from hypothalamic neurons expressing agouti-related peptide (AgRP) was genetically inactivate
37 of hypothalamic 'hunger neurons' (expressing agouti-related peptide (AgRP)) bypasses these signals to
38 (alpha-MSH), an endogenous MC4R agonist, and agouti-related peptide (Agrp), an endogenous MC4R antago
40 lanocyte stimulating hormone (alpha-MSH) and agouti-related peptide (AGRP), on feeding behavior and e
41 iomelanocortin (POMC), neuropeptide Y (NPY), agouti-related peptide (AGRP), somatostatin, and dopamin
42 a-MSH) and to an antagonist/inverse agonist, agouti-related peptide (AgRP), which are released by ups
43 ific Cre-driver mice to reexpress RIIbeta in agouti-related peptide (AgRP)-, proopiomelanocortin (POM
44 es the activity of neuropeptide Y (NPY)- and agouti-related peptide (AgRP)-co-producing (NPY/AgRP) ne
47 expressing and hunger signaling (orexigenic) agouti-related peptide (AgRP)-expressing neurons are key
55 hibition of neural melanocortin receptors by agouti-related peptide also attenuated rhythmicity in th
56 A expression of the orexigenic neuropeptides Agouti-related peptide and melanin-concentrating hormone
57 kinase kinase beta or AMPK greatly increases Agouti-related peptide and melanin-concentrating hormone
58 e excited orexigenic neurons that synthesize agouti-related peptide and neuropeptide Y but inhibited
59 striction, MSI-1436 decreased mRNA levels of agouti-related peptide and neuropeptide Y in the hypotha
62 subsets (proopiomelanocortin, neuropeptide Y/agouti-related peptide, and steroidogenic factor 1), tho
63 coadministration of the alpha-MSH antagonist agouti-related peptide blocked the anorexigenic effects
65 knockdown of Sirtuin 1 Sirt1 in hypothalamic Agouti-related peptide-expressing neurons, which renders
66 2-null mice, while the density of orexigenic agouti-related peptide fibers in the mutant mice appeare
67 ding those producing pro-opiolemelanocortin, agouti-related peptide, hypocretin/orexin, melanin-conce
70 t on brain systems utilizing neuropeptide Y, agouti-related peptide, melanocortins, orexins, and mela
73 increase in the appetite-regulating proteins agouti-related peptide, neuropeptide Y, and uncoupling p
74 vity, and expression of pro-opiomelanocortin/agouti-related peptide/neuropeptide Y in the hypothalamu
75 etrogradely labeled neurons contained either agouti-related peptide or cocaine/amphetamine-regulated
76 ne or hypothalamic levels of neuropeptide Y, agouti-related peptide, pro-opiomelanocortin, or cocaine
77 several hypothalamic neuropeptides, notably agouti-related peptide, proopiomelanocortin, and neurope
78 ice administered the MC3-R/MC4-R antagonist, agouti-related peptide, resist tumor-induced loss of lea
79 ter (that controlling the Agrp gene encoding agouti-related peptide) responsive to BDNF-induced physi
80 wise, treatment of WT mice with intracranial agouti-related peptide reversed the cachexic effects of
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