ライフサイエンスコーパス: agouti-related protein

1 ortin with an increase in neuropeptide Y and agouti-related protein.

2 dullin (hazard ratio per log increase 2.53), agouti-related protein; (1.48), chitinase-3-like protein

3 ed expression of the orexigenic neuropeptide agouti related protein (AgRP) in the BMPR1A-deficient AR

4 Agouti related protein (AGRP)-expressing neurons are a k

5 Agouti-related protein (Agrp) (83-132), a biologically a

6 ssing the endogenous melanocortin antagonist agouti-related protein (AgRP) also exhibit obesity, incr

7 Agouti-related protein (AgRP) and agouti signaling prote

8 Agouti-related protein (AgRP) and neuropeptide Y (NPY) a

9 w that changes in hypothalamic expression of agouti-related protein (Agrp) and neuropeptide Y (Npy) c

10 e expression of the orexigenic neuropeptides agouti-related protein (AgRP) and neuropeptide Y (NPY).

11 ) whether food deprivation (FD) co-increases agouti-related protein (AgRP) and PPARgamma mRNA express

12 we examined the role of insulin signaling in agouti-related protein (AgRP) and pro-opiomelanocortin (

13 Agouti-related protein (AGRP) and proopiomelanocortin (P

14 t, the endogenous antagonists Agouti and the Agouti-related protein (AGRP) and signals through the in

15 Agouti protein and the Agouti-related protein (AGRP) are antagonists of the mel

16 Agouti protein and Agouti-related protein (Agrp) are paracrine-signaling mo

17 eurons that express neuropeptide Y (NPY) and agouti-related protein (AgRP) are thought to be critical

18 We found that impairment of Agouti-related protein (AgRP) circuitry by either Sirt1

19 imulating hormone (alpha-MSH) and orexigenic Agouti-related protein (AgRP) from discrete hypothalamic

20 the ability of proopiomelanocortin (POMC) or agouti-related protein (Agrp) hypothalamic neurons to se

21 ablation of hypothalamic neurons expressing agouti-related protein (AgRP) in adult mice leads to ano

22 Ablation of neurons that make agouti-related protein (AgRP) in moderately obese adult

23 ASIP, and its neuropeptide homolog the agouti-related protein (AgRP) involved in energy balance

24 C), reduce food intake, whereas hypothalamic agouti-related protein (AgRP) is a MC-4 receptor antagon

25 Agouti-related protein (AGRP) is a potent orexigenic pep

26 The agouti-related protein (Agrp) is a powerful orexigenic p

27 Agouti-related protein (AGRP) is a recently discovered o

28 Agouti-related protein (AGRP) is an endogenous antagonis

29 The agouti-related protein (AGRP) is an endogenous antagonis

30 Agouti-related protein (AGRP) is an endogenous antagonis

31 Agouti-related protein (AGRP) is an endogenous antagonis

32 The agouti-related protein (AGRP) is an endogenous antagonis

33 The agouti-related protein (AGRP) is an endogenous antagonis

34 The agouti-related protein (AgRP) is an orexigenic peptide t

35 The neuropeptide agouti-related protein (AgRP) is expressed in the arcuat

36 Agouti-related protein (AGRP) is one of only two natural

37 Agouti-related protein (AGRP) is one of two known natura

38 olves targeting the human DT receptor to the agouti-related protein (Agrp) locus so that systemic adm

39 Hypothalamic neuropeptide Y (NPY) and agouti-related protein (AgRP) mRNA expression increased

40 examine the importance of GABA release from agouti-related protein (AgRP) neurons (which also releas

41 examine the importance of GABA release from agouti-related protein (AgRP) neurons (which also releas

42 Among these, agouti-related protein (AgRP) neurons are thought to pro

43 crease but their size increase in orexigenic agouti-related protein (Agrp) neurons during the transit

44 Agouti-related protein (AgRP) neurons in the ARC (ARC(Ag

45 Pro-opiomelanocortin (POMC) and agouti-related protein (AGRP) neurons in the hypothalamu

46 used targeted knock-ins to express InsRs in agouti-related protein (AgRP) or proopiomelanocortin (PO

47 ther, CTRP13 and the orexigenic neuropeptide agouti-related protein (AgRP) reciprocally regulate each

48 Agouti protein and Agouti-related protein (Agrp) regulate pigmentation and

49 ithin the hypothalamus, neurons that express agouti-related protein (AgRP) sense orexigenic factors a

50 ortin sequence-based MC4R antagonists vs the agouti-related protein (AGRP) sequence-based antagonists

51 We used a truncated form of the Agouti-related protein (AgRP), a 4-kDa cystine-knot pept

52 Agouti-related protein (Agrp), a high-affinity antagonis

53 Because agouti-related protein (AGRP), a leptin-regulated, arcua

54 Agouti-related protein (AgRP), a melanocortin receptor a

55 Agouti-related protein (AgRP), a neuropeptide abundantly

56 The Agouti-related protein (AGRP), an appetite modulator, in

57 ion of key orexigenic [neuropeptide Y (NPY), agouti-related protein (AgRP), and melanin-concentrating

58 pically express either agouti (Ay/a mice) or agouti-related protein (Agrp), antagonists of melanocort

59 (A(y)) mice, and causes obesity by mimicking agouti-related protein (Agrp), found primarily in the hy

60 re, the endogenous MC3R and MC4R antagonist, agouti-related protein (AgRP), hyperpolarizes POMC and R

61 ortin receptor (MC3-R and MC4-R) antagonist, agouti-related protein (AGRP), is a potent stimulant of

62 The endogenous MC4R antagonist, agouti-related protein (AGRP), is expressed in the brain

63 e (alpha-MSH) and its endogenous antagonist, agouti-related protein (AgRP), is fundamental for the ce

64 Hypothalamic neurons that co-express agouti-related protein (AgRP), neuropeptide Y and gamma-

65 Neuropeptide Y (NPY) and agouti-related protein (AgRP), potent stimulants of feed

66 A expression levels of neuropeptide Y (NPY), agouti-related protein (AGRP), proopiomelanocortin (POMC

67 luding those producing neuropeptide Y (NPY), Agouti-related protein (AGRP), proopiomelanocortin (POMC

68 othalamic GHS-R1a, neuropeptide Y (NPY), and agouti-related protein (AgRP), suggesting that prolonged

69 are absent in mice lacking the gene encoding agouti-related protein (Agrp), suggesting that this func

70 Neuropeptide Y (NPY) and Agouti-related protein (AgRP), two orexigenic neuropepti

71 gonists, agouti signaling protein (ASIP) and agouti-related protein (AGRP), were assessed by studying

72 neurons containing neuropeptide Y (NPY) and agouti-related protein (AgRP), which are conditional pac

73 eceptors are antagonized by agouti (ASP) and agouti-related protein (AGRP), which are the only known

74 Ablation of inhibitory agouti-related protein (AgRP)-expressing neurons in the

75 We show that agouti-related protein (AgRP)-expressing neurons precede

76 anocortin (POMC) or neuropeptide-Y (NPY) and agouti-related protein (AgRP).

77 agonists, agouti-signaling protein (ASP) and agouti-related protein (AGRP).

78 endogenous antagonists of GPCRs, agouti and agouti-related protein (AGRP).

79 effects of ACTH were blocked by SHU9119 and agouti-related protein (AGRP).

80 ne (alpha-MSH) and the orexigenic antagonist agouti-related protein (AGRP).

81 g hormone (alpha-MSH) or antagonists such as agouti-related protein (AgRP).

82 ture-activity relationship study of chimeric agouti-related protein (AGRP)/[Nle4,DPhe7]alpha-melanocy

83 enic neuropeptides [neuropeptide Y (NPY) and agouti-related protein (AgRP)] and activates expression

84 lpha-MSH(4-10)-NH(2) (SHU9119)] and natural [agouti-related protein (AGRP)] MC3R antagonists but not

85 e appetite-stimulating (neuropeptide Y, NPY; agouti-related protein, AGRP) and appetite-inhibiting (c

86 gen, decreases AMPK activity in PVH, whereas agouti-related protein, an orexigen, increases AMPK acti

87 S chains, syndecans potentiate the action of agouti-related protein and agouti signaling protein, end

88 ing hormone, oxytocin, arginine vasopressin, agouti-related protein and alpha-melanocyte stimulating

89 orexigenic neuropeptides neuropeptide Y and agouti-related protein and down-regulation of expression

90 The hypothalamic levels of agouti-related protein and neuropeptide Y RNA are increa

91 ons but has limited effect on neuropeptide Y/agouti-related protein and proopiomelanocortin neurons.

92 be mediated by leptin action on arcuate NPY/agouti-related protein and proopiomelanocortin neurons.

93 ession of key orexigenic (neuropeptide Y and agouti-related protein) and anorexigenic (pro-opiomelano

94 Agouti protein and agouti-related protein are homologous paracrine signalli

95 lls, with a notable lack of projections from agouti-related protein-expressing neurons.

96 howed that in the DMH abundant alpha-MSH and agouti-related protein fibers are in close apposition to

97 er evaluated using the endogenous antagonist agouti-related protein fragment hAGRP(83-132) and hAGRP(

98 The agouti-related protein gene (Agrp) is a novel gene impli

99 The agouti-related protein gene (Agrp) plays an important ro

100 adrenocorticotropin (ACTH)], the antagonist agouti-related protein hAGRP(87-132), and synthetic agon

101 Hypothalamic neurons that express agouti-related protein have been thought to regulate app

102 rons were stained for a second neuropeptide, agouti-related protein, immunoreactivity was found in th

103 Thus, Agouti-related protein is a neuropeptide implicated in t

104 Hence, as body weight decreased and agouti-related protein is induced, microRNA expression w

105 The murine agouti related protein (mAGRP) is upregulated in obese a

106 weight, and hypothalamic neuropeptide Y and Agouti-related protein mRNA expression.

107 and elevated hypothalamic neuropeptide-Y and agouti-related protein mRNA levels.

108 1, which caused increased neuropeptide Y and agouti-related protein mRNAs in the hypothalamus, stimul

109 sm in proopiomelanocortin and neuropeptide Y/agouti-related protein neurons and links hypothalamic AM

110 ate nucleus, specifically the neuropeptide Y/agouti-related protein neurons and the dorsal medial nuc

111 CK1 in either pro-opiomelanocortin (POMC) or agouti-related protein neurons, mediators of leptin acti

112 absence of MRAP2, fasting fails to activate agouti-related protein neurons.

113 ivation of ARC glia enhances the activity of agouti-related protein/neuropeptide Y (AgRP/NPY)-express

114 RNAs in the hypothalamus, stimulation of the agouti-related protein/neuropeptide Y neurons, and activ

115 s neurons that co-express neuropeptide Y and agouti-related protein (NPY/AgRP neurons).

116 Recombinant Agouti-related protein was a potent, selective antagonis

117 sed sequence tag was identified that encodes Agouti-related protein, whose RNA is normally expressed