ライフサイエンスコーパス: airway obstruction

1 wed by eosinophil-dominated inflammation and airway obstruction.

2 nflammation, mucus production and reversible airway obstruction.

3 p asthma, a serious disorder of intermittent airway obstruction.

4 ssion of miR-218-5p strongly correlated with airway obstruction.

5 xacerbate the inflammatory process and cause airway obstruction.

6 s, and the risk of asphyxiation due to upper airway obstruction.

7 distal airways in association with clinical airway obstruction.

8 ates in subepithelial fibrosis with variable airway obstruction.

9 tress in the lung and limiting the degree of airway obstruction.

10 airway hyperreactivity (AHR) and reversible airway obstruction.

11 ce, increased pulmonary edema, and extensive airway obstruction.

12 LP and TARC/CCL17 expression correlated with airway obstruction.

13 and LOA (P = 0.0003) scores than those with airway obstruction.

14 tein level and correlated with the degree of airway obstruction.

15 correlated with TARC and MDC expression and airway obstruction.

16 ranging from infrequent recurrence to acute airway obstruction.

17 ses with the progression of malnutrition and airway obstruction.

18 is a hallmark of asthma that contributes to airway obstruction.

19 atients with COPD who do not have reversible airway obstruction.

20 lification loop, mucosal IFN expression, and airway obstruction.

21 nd quality of life with treatment of central airway obstruction.

22 disruption that occurs in response to upper airway obstruction.

23 ema, abnormal lung compliance, and extensive airway obstruction.

24 nflammatory disease of the lung resulting in airway obstruction.

25 fetal lesions causing extrinsic or intrinsic airway obstruction.

26 r, and extubation failure secondary to upper airway obstruction.

27 to diacetyl and the frequency and extent of airway obstruction.

28 obin concentration, and hypoxemia from upper airway obstruction.

29 d by neuromuscular blockade with and without airway obstruction.

30 a chronic disease of the lung resulting from airway obstruction.

31 mechanically ventilated patients with severe airway obstruction.

32 l than inspiratory CT for diagnosis of small airway obstruction.

33 48 hrs of extubation in the absence of upper airway obstruction.

34 tic complications had satisfactory relief of airway obstruction.

35 were necessary to achieve adequate relief of airway obstruction.

36 rproduction, a condition that contributes to airway obstruction.

37 malities were identified in all animals with airway obstruction.

38 sociated genes correlates with the degree of airway obstruction.

39 fects, usually congenital, that cause severe airway obstruction.

40 men 35 to 60 yr of age with mild-to-moderate airway obstruction.

41 that HFO at 15 Hz resulted in greater large airway obstruction.

42 ute to the mechanism by which LVRS palliates airway obstruction.

43 iveness that can proceed to life-threatening airway obstruction.

44 48 hrs of extubation in the absence of upper airway obstruction.

45 aracterized by eosinophilic inflammation and airway obstruction.

46 direct effects on mast cell-driven allergic airway obstruction.

47 ay be less sensitive in regard to peripheral airway obstruction.

48 is closely related to both EMT activity and airway obstruction.

49 ypical symptoms in combination with variable airway obstruction.

50 causes severe lung inflammation, leading to airway obstruction.

51 eterminant for initiating RSV-induced distal airway obstruction.

52 ic epithelial cells, leading to acute distal airway obstruction.

53 d produce mucus, an important contributor to airway obstruction.

54 offspring, thereby predisposing to postnatal airway obstruction.

55 ografts is attributable to progressive small airway obstruction.

56 nic endobronchial infection, and progressive airway obstruction.

57 circulating granulocytes that caused severe airway obstruction.

58 examine independently both small- and large-airway obstruction.

59 He had mild reversible airway obstruction.

60 urgical procedures for the relief of central airway obstructions.

61 stration aids resolution of these functional airway obstructions.

62 imilar for patients with concomitant chronic airways obstruction.

63 urces for COPD patients with moderate/severe airways obstruction.

64 the same time that the FEV1 revealed ongoing airways obstruction.

65 rrence of laryngeal lesions with the risk of airways obstruction.

66 ver, only asthma is associated with variable airways obstruction.

67 reintubation was classified as airway (upper airway obstruction, 11; aspiration/excess pulmonary secr

68 Common reasons for exclusion were upper airway obstruction (13.5%) and cyanotic congenital heart

69 studied 3, 926 smokers with mild-to-moderate airway obstruction (3,818 with analyzable results; mean

70 ontrolled, and with severe exacerbations and airway obstruction (41.3% of patients); and class 4, poo

71 [aOR], 1.93; 95% CI, 1.06-3.55; P = .03) and airway obstruction: 50% of forced expiratory flow (abeta

72 used spirometry as the primary assessment of airway obstruction, a method that may be less sensitive

73 al pulmonary function compared to those with airway obstruction after adjusting for age, race, gender

74 Asthma is characterized by variable airway obstruction, airway hyperresponsiveness, and airw

75 sthma is a complex syndrome characterized by airway obstruction, airway inflammation and airway hyper

76 ether obese asthma patients have more severe airway obstruction and airway hyper-responsiveness and a

77 of the lung, is characterized by reversible airway obstruction and airway hyperresponsiveness (AHR),

78 ronchitis, C fibers limit the development of airway obstruction and airway hyperresponsiveness during

79 iated with airway hyperresponsiveness (AHR), airway obstruction and airway remodelling.

80 essive lung disease culminating in permanent airway obstruction and alveolar enlargement.

81 sure to cigarette smoke (CS), which involves airway obstruction and alveolar loss (i.e., emphysema).

82 ronchial asthma is characterized by episodic airway obstruction and associated with wheezing, a bronc

83 lergic asthma is characterized by reversible airway obstruction and bronchial hyperresponsiveness ass

84 inflammatory response that leads to chronic airway obstruction and bronchiectasis.

85 orced vital capacity, a sensitive measure of airway obstruction and bronchodilator response, which me

86 The relative contributions of airway obstruction and central hypoventilation could not

87 The model differentiates between upper airway obstruction and complications like bronchospasm a

88 way mucus overproduction that contributes to airway obstruction and death.

89 to 1.9 +/- 1.3 cm H2O, leading to increasing airway obstruction and decreasing levels of inspiratory

90 pecimens, was not associated with reversible airway obstruction and did not correlate with the severi

91 Rint was increased in the patient with lower airway obstruction and five of six patients without prim

92 cal and physiological predispositions toward airway obstruction and gas exchange abnormalities; inclu

93 They also had the greatest airway obstruction and hyperreactivity compared with the

94 c mice developed clinical disease, including airway obstruction and hyperresponsiveness (AHR), along

95 Airway obstruction and hyperresponsiveness do not change

96 Previously we observed some adult rats had airway obstruction and hyperresponsiveness following bro

97 zed anticoagulants will reduce the degree of airway obstruction and improve pulmonary function in she

98 The treatment reduced the degree of airway obstruction and improved pulmonary gas exchange,

99 ulation) are potentially at risk for greater airway obstruction and increased asthma morbidity.

100 s, and physiological abnormalities including airway obstruction and increased lung compliance.

101 ons through the airway epithelium will limit airway obstruction and inflammation and may be therapeut

102 in acute lung injury due to a combination of airway obstruction and inflammation.

103 hronic respiratory disease, characterized by airway obstruction and inflammation.

104 Airway obstruction and injury scores were not different

105 tudy was to examine the relationship between airway obstruction and periodontal disease.

106 tion of some complications, especially upper airway obstruction and possibly immune-mediated anemia a

107 nchiolitis can damage the airways to promote airway obstruction and recurrent wheezing.

108 ncludes preoperative treatment of reversible airway obstruction and respiratory infections, smoking c

109 smoking is associated with evidence of mild airway obstruction and slowed growth of lung function in

110 n activity during sepsis might induce severe airway obstruction and that supplementation with antithr

111 sion in asthmatics with different degrees of airway obstruction and the validity of proposed TMAD-cor

112 sential to understand the pathophysiology of airway obstruction and to identify novel therapeutic tar

113 lometry reactance area indicating peripheral airway obstruction and urinary leukotriene E(4) levels i

114 er increased MUC5AC secretion alone produces airway obstruction and/or inflammation, we generated a m

115 uggest that excessive mucin secretion causes airways obstruction and inflammation.

116 ith parenchymal lung disease; one with lower airway obstruction) and six without primary lung disorde

117 tified genes are also involved in emphysema, airway obstruction, and bronchial inflammation.

118 s respond to adenosine challenge with marked airway obstruction, and concentrations of adenosine are

119 ase characterized by airway hyperreactivity, airway obstruction, and histologic inflammation.

120 groups of features: atopic burden, degree of airway obstruction, and history of exacerbation.

121 -linking Ab that prevents lung inflammation, airway obstruction, and hyperreactivity to allergen in a

122 mation and contributes to clinical symptoms, airway obstruction, and mortality.

123 ong channels included body movement, partial airway obstruction, and obstructed breaths.

124 littermate controls; identified locations of airway obstruction, and quantified regions of bimodal ai

125 , and 1 (6%) each from tension pneumothorax, airway obstruction, and sepsis.

126 ated with increases in lung edema formation, airway obstruction, and vascular endothelial growth fact

127 ystals, airway fibrosis, eotaxin production, airways obstruction, and nonspecific AHR.

128 ty is mostly caused by bronchiectasis, small airways obstruction, and progressive respiratory impairm

129 hy, before and after methacholine, to assess airway obstruction (AO) and airway hyperreactivity (AHR)

130 tion, IFN-gamma:IL-4 mRNA expression ratios, airway obstruction (AO), and airway hyperreactivity (AHR

131 ed with acute morbidity (e.g., pneumonia and airway obstruction [AO]) and long-term complications (e.

132 disorders ranging from altitude sickness to airway obstruction, apnea, and atelectasis.

133 hicle-treated bronchi resulted in late-phase airway obstruction (approximately 120% increase over bas

134 tested the hypotheses that markers of small airway obstruction are associated with (i) increased ast

135 ng cancer; however, benign causes of central airway obstruction are being seen more frequently as wel

136 Current methods for studying airway obstruction are inadequate in safety, cost, or av

137 t cell metaplasia, mucus hypersecretion, and airway obstruction are integral features of inflammatory

138 e of chronic lung allograft failure is small airway obstruction arising from bronchiolitis obliterans

139 n steroid treatment ethane was correlated to airway obstruction as assessed by the ratio of residual

140 Histopathology revealed pulmonary edema and airway obstruction as the morphologic correlates of the

141 CD4(+) and CD8(+) T cells completely blocked airway obstruction as well as AHR.

142 analysis is the first to suggest that small-airway obstruction, as assessed based on FEF25-75, might

143 n the guinea pig aerosolized antigen induced airway obstruction assay (ED50 2.0 mg/kg, po) and demons

144 n the guinea pig aerosolized antigen induced airway obstruction assay (ED50 8.8 mg/kg, po) and demons

145 dy shows that with control for the degree of airway obstruction, asthma, as defined, is more common i

146 ontrols at 245 days (P = 0.03) and increased airway obstruction at 530 days (P = 0.01).

147 ssociated with a younger age and less severe airway obstruction at first testing, odds ratios (OR) be

148 criteria of attacks of wheezing, reversible airway obstruction, atopy, and that increased IgE.

149 Control and COPD subjects with mild airways obstruction (baseline FEV(1) >/= 50% predicted)

150 of pulmonary nitrosative stress (p = 0.002), airway obstruction (bronchi: p = 0.001, bronchioli: p =

151 ood lipid profile is associated with asthma, airway obstruction, bronchial responsiveness, and aeroal

152 posure to POPs appears to be associated with airway obstruction but not allergic sensitization at 20

153 The genotype increased the odds of airway obstruction by 75% within asthmatics only.

154 th aerosolized heparin attenuated late-phase airway obstruction by approximately 50%, inhibited eosin

155 inically similar asthma patients may develop airway obstruction by different mechanisms.

156 ppears to be a major mechanism through which airway obstruction by spasmogens is avoided.

157 cough by 56% and maximal Penh (a measure of airway obstruction) by 43%, effects that were attenuated

158 e beneficial to most patients and almost all airway obstruction can be relieved expeditiously.

159 ry disease that is characterized by variable airways obstruction caused by acute and chronic bronchia

160 n severe asthma may relate to the peripheral airway obstruction characteristic of this condition.

161 ome 17q21 locus relates to episodes of acute airway obstruction common to both transient wheeze and a

162 We conclude that airway obstruction commonly occurs in patients with Fabr

163 gic agonist bronchodilators to patients with airways obstruction commonly results in transient decrea

164 tion and burn injury, bronchospasm and acute airway obstruction contribute to progressive pulmonary i

165 Whether small-airway obstruction contributes to the long-term evolutio

166 inhaled bronchodilators to partially improve airway obstruction, corticosteroids to decrease the like

167 Greater airway obstruction [decreased forced expiratory volume i

168 e patients with asthma developed significant airway obstruction (deltaFEV1, -27.7 +/- 2.9%; p = 0.000

169 tients, the presence, location, and cause of airway obstruction determined at MR imaging were confirm

170 Previously reported markers of small airway obstruction do not appear to be independently ass

171 surements correlate with the degree of upper airway obstruction during sleep and may have a role in t

172 ea (OSA) is characterized by recurrent upper airway obstruction during sleep.

173 include a positive response to albuterol and airway obstruction, factors that could help identify app

174 = 0.47, P = 0.04; AMC: r = 0.45, P = 0.04), airway obstruction (FEV(1): r = 0.68, P = 0.001), and ar

175 owever, positively associated with offspring airway obstruction (FEV1 /FVC < 75%).

176 genes in BECs from children with asthma and airway obstruction (FEV1/forced vital capacity < 0.85 an

177 R-142-3p expression was associated also with airway obstruction (FEV1/forced vital capacity).

178 200 cells/microliter) was 90% in predicting airway obstruction (FEV1/FVC < 0.8).

179 s had severe Brasfield scores (9.0 +/- 3.2), airways obstruction (FEV1 25.6 +/- 5.6% predicted, FEF(2

180 piratory volume in 1 s [FEV1]) and increased airways obstruction (FEV1 as a percentage of forced vita

181 any neuromuscular disorders mechanical upper airway obstruction from oropharyngeal weakness contribut

182 tient received RF ablation for prevention of airway obstruction from progressive diffuse large B-cell

183 Many modalities for central airway obstruction have emerged, including the expanding

184 In mechanically ventilated patients with airway obstruction, helium-oxygen (He-O2) mixtures reduc

185 length of ventilation, postextubation upper airway obstruction, high respiratory effort postextubati

186 disease, lower aPiMax, postextubation upper airway obstruction, higher preextubation positive end-ex

187 Asthma is a chronic lung disease exhibiting airway obstruction, hyperresponsiveness, and inflammatio

188 In asthma, the mechanisms relating airway obstruction, hyperresponsiveness, and inflammatio

189 n between exposure to fuel oil ash and acute airway obstruction in 31 boilermakers and 31 utility wor

190 matrix metalloprotease levels in sputum, and airway obstruction in a cohort of human immunodeficiency

191 Inhaled bitter tastants decreased airway obstruction in a mouse model of asthma.

192 better discrimination between normality and airway obstruction in adults of at least these three eth

193 situations, albuterol does not relieve acute airway obstruction in all asthmatic individuals with equ

194 n important factor contributing to increased airway obstruction in allergen-induced exacerbation of a

195 ed Cl- secretion is essential for preventing airway obstruction in allergic airway disease.

196 Mucous hypersecretion is a major cause of airway obstruction in asthma, chronic obstructive pulmon

197 y of inflammatory diseases, in particular of airway obstruction in asthma.

198 mportant clinical symptom and contributes to airway obstruction in asthma.

199 the mucus gel or how this gel contributes to airway obstruction in asthma.

200 nism has implications for the development of airway obstruction in asthma.

201 I could contribute to the pathophysiology of airway obstruction in asthmatic patients.

202 new role for FENO in identifying the site of airway obstruction in asthmatic patients.

203 associated with markers of inflammation and airway obstruction in asthmatic subjects exposed to anti

204 designing novel therapies to reverse MCM and airway obstruction in asthmatics.

205 ometric measurements to identify patterns of airway obstruction in children and define obstruction ph

206 ne decreases the frequency of postextubation airway obstruction in children.

207 begs the question, Is it possible to reduce airway obstruction in chronic lung disease by inhibiting

208 modeling, which contributes significantly to airway obstruction in chronic obstructive pulmonary dise

209 is common in smokers and is associated with airway obstruction in chronic obstructive pulmonary dise

210 is an important predictor of progression of airway obstruction in continuing smokers with early COPD

211 A major mechanism of airway obstruction in COPD is thickening of the small ai

212 ly cause conductive hearing loss in COME and airway obstruction in COPD.

213 t association between periodontal health and airway obstruction in former smokers.

214 The genes HHIP and FAM13A confer a risk for airway obstruction in general that is not driven exclusi

215 ade in the prevention and treatment of upper airway obstruction in infancy and childhood.

216 ssive airway mucin production contributes to airway obstruction in lung diseases such as asthma and c

217 We determined whether upper airway obstruction in normal individuals with intact ref

218 st and safe tool to identify simulated sleep airway obstruction in patients with OSA.

219 Abundant airway mucus contributes to airway obstruction in RSV disease.

220 th conventional tracheal suction, to prevent airway obstruction in sheep with the ETT and trachea ori

221 The role of small airway obstruction in the clinical expression of asthma

222 te this association, PAI-1 may contribute to airway obstruction in the context of chronic asthmatic a

223 n tests revealed air trapping and mild lower airway obstruction in the ECMO group, compared with mean

224 structural component in determining variable airways obstruction in asthma.

225 Airway obstruction, including AHR and airway resistance,

226 upational lung disease marked by restrictive airway obstruction, inflammation, and fibrosis.

227 Airway obstruction is a hallmark of allergic asthma and

228 Airway obstruction is a physiologic feature of asthma, a

229 Central airway obstruction is a problem facing all medical and s

230 e observed that IL-15-mediated protection of airway obstruction is associated with induced IFN-gamma-

231 The other main cause of airway obstruction is contraction of airway smooth muscl

232 We conclude that reversible airway obstruction is found in LAM patients with acceler

233 asminogen activator inhibitor-1 (PAI-1) with airway obstruction is modified by asthma status, and whe

234 The mere association of exercise and airway obstruction is not sufficient to establish the di

235 Even though upper airway obstruction is potentially life-threatening, a se

236 hetic drug-induced respiratory depression or airway obstruction leading to hypoxemia or hypoventilati

237 The putative small airway obstruction markers Sacin , resistance at 5 Hz mi

238 Colonized subjects exhibited more severe airway obstruction (median FEV(1) = 21% predicted versus

239 Of those patients with airway obstruction, more than 50% showed a bronchodilato

240 Although asthma is characterized by variable airways obstruction, most studies of asthma phenotypes a

241 y increases toward areas most susceptible to airway obstruction (nose < bronchi << bronchioles).

242 mpliance (p = 0.005) than control rats, with airway obstruction occurring in an episodic pattern.

243 that demonstrated the variable extrathoracic airway obstruction of vocal cord dysfunction.

244 stigate the effect of nutritional status and airway obstruction on diaphragm strength.

245 Nine (36%) had airway obstruction on spirometry; this finding was assoc

246 ever therapy only) do not present reversible airway obstruction or airway hyperresponsiveness to indi

247 39% increase in risk of clinically relevant airway obstruction (OR=1.39, CI: 1.01, 1.92, P=.04).

248 association between periodontal disease and airway obstruction, particularly in former smokers.

249 Airway obstruction plays an important role in pulmonary

250 chytherapy is an effective method to relieve airway obstruction promptly for patients with recurrent

251 ), and forced expiratory volume in 1 second (airway obstruction, r = 0.7; 95% CI: 0.21, 0.91).

252 y subjects, patients with moderate-to-severe airways obstruction receive an increased dose from ultra

253 ve bronchiolitis and progressively worsening airway obstruction refractory to conventional immune sup

254 When children developed postextubation upper airway obstruction, reintubation rates were 47.4% for th

255 values in asthmatic patients as a result of airway obstruction relief occurring at different lung de

256 er bronchodilation, depending on the site of airway obstruction relief.

257 Despite all these advances, upper airway obstruction remains an important source of morbid

258 characterized by impaired lung function and airway obstruction resulting from interactions between m

259 Selection criteria include marked airway obstruction secondary to emphysema, marked hyperi

260 t regimen helped to resolve life-threatening airway obstruction secondary to fibrin casts.

261 Airway obstruction secondary to recurring casts improved

262 However, upper airway obstruction secondary to severe bleeding in the f

263 r transplantation in smokers with a range of airway obstruction severity and in a control group with

264 A case-control study of airway obstruction showed that waist circumference was s

265 = 10) and in subjects with varying levels of airway obstruction: smokers (S; n = 10), smokers with sm

266 uamation and mucus hypersecretion leading to airway obstruction, subepithelial fibrosis, airway smoot

267 cumulation of these cells is associated with airway obstruction, suggesting that they may play a sign

268 Congenital high airway obstruction syndrome (CHAOS) is a rare fetal anom

269 of 24 cases by demonstrating congenital high airway obstruction syndrome, congenital hemochromatosis,

270 es have a clinically significant role in the airway obstruction that characterizes asthma.

271 plays an intimate role in the development of airway obstruction that follows hyperpnea.

272 sleep causing snoring and, in serious cases, airway obstruction that interrupts breathing, a conditio

273 pressures, pulmonary dysfunction, and upper airway obstruction that occur after combined smoke inhal

274 s, but also to prevent recurrent symptoms of airway obstruction that occur in some children for years

275 IL-15 has a potent inhibitory effect on the airway obstruction that occurs in response to environmen

276 e likely caused by relief of an intra-acinar airway obstruction that we propose reflects amplificatio

277 In addition to airway obstruction, the loss of hypoxic pulmonary vasoco

278 ted an association between Fabry disease and airway obstruction, this has not been investigated in a

279 e workers had 3.3 times the expected rate of airway obstruction; those who had never smoked had 10.8

280 logical processes spanning the spectrum from airway obstruction to lung remodeling can lead to multif

281 clinically significant post-extubation upper airway obstruction (UAO) and differentiate subglottic fr

282 ese symptoms and demonstration of reversible airway obstruction using spirometry.

283 s of these regimens on lung injury severity, airway obstruction, ventilation, oxygenation, pulmonary

284 Quantifying underlying small airway obstruction via PRM(fSAD) helps further stratify

285 Airway obstruction was created by inflating a 5-F balloo

286 ung mechanics, whether the postbronchiolitis airway obstruction was episodic or continuous, and to de

287 Upper airway obstruction was produced in 12 normal individuals

288 Moderate to severe airway obstruction was seen in 3.6%.

289 Airway obstruction was seen, starting from generation 6

290 Airway obstruction was statistically elevated in MpIL12

291 a 1-antitrypsin deficiency (alpha 1-ATD) and airway obstruction, we compared 38 patients who had this

292 ases in enhanced pause (Penh) as an index of airway obstruction, we measured responses to inhaled met

293 pacity and to markers for hyperinflation and airway obstruction were found in patients with CF.

294 Two levels of upper airway obstruction were induced in ten dogs by partially

295 chronic syndrome of intermittent, reversible airway obstruction which has multiple parallels with hum

296 in elderly patients with severe irreversible airway obstruction, withdrawal of inhaled corticosteroid

297 ociation of the polymorphism with asthma and airway obstruction within asthmatics via multivariate lo

298 in elderly patients with severe irreversible airway obstruction would not lead to a deterioration in