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1 on with a CCD inhibitor (MUXF(3)-human serum albumin).
2 chanism even in the presence of low doses of albumin.
3 h circulating concentrations of both IgG and albumin.
4 trypsin inhibitor-1) and a heterodimeric 2S albumin.
5 articipants received supportive therapy with albumin.
6 matography based purification of human serum albumin.
7 removed, yielding fully mature heterodimeric albumin.
8 peptides from trypsin digested bovine serum albumin.
9 ng plays a main role in the binding of SA to Albumin.
10 echanism even after exposure to low doses of albumin.
11 ding albumin variant compared with wild-type albumin.
12 ells and does not interact with bovine serum albumin.
13 ifact of acetic acid-mediated degradation of albumin.
14 d microvessel permeability to both water and albumin.
15 ntrols and was detected earlier than urinary albumin.
16 ding pathway for a group of homologous serum albumins.
19 gnificant increase in albumin oxidation, and albumin acts as a pro-oxidant; this promotes oxidative s
21 hat both small molecules were able to confer albumin affinity to GLP-1 and indicated that affinity is
22 intracelluar uptake of fluorescently labeled albumin after intradermal injection by LECs was similar
23 stigating the advanced glycation end-product-albumin (AGE-albumin) from activated macrophages is crit
25 efining certain secretory cellular lineages: albumin (ALB) in liver carcinoma, gastric lipase (LIPF)
27 biVax), here we develop clinically promising albumin/AlbiVax nanocomplexes that self-assemble in vivo
28 G and antigens (Ags) to lymph nodes (LNs) by albumin/AlbiVax than benchmark incomplete Freund's adjuv
29 s index, haemoglobin, serum uric acid, serum albumin, albuminuria, and C reactive protein as non-GFR
31 herent property to interact selectively with albumin among different biomolecules in intracellular en
34 ularly notable is the strong upregulation of albumin and fibrinogen genes, which suggest significant
35 s were found in the relationship of glycated albumin and fructosamine levels with the mean glucose co
36 a model that low levels of HBsAg, HBcAb, and albumin and high fibrosis values predicted strong antivi
38 uation of Cav-1 expression reduced uptake of albumin and nab-paclitaxel in cancer cells and rendered
39 teine, homocysteine, glutathione, quercetin, albumin and tannic reduce bioavailability of both mercur
40 f lipid binding to the soluble protein serum albumin and to the integral membrane protein NapA shows
41 recycling and bidirectional transcytosis of albumin and uniquely determines the physiologic release
43 d hemoglobin (HbA1c), fructosamine, glycated albumin), and a latent variable for kidney function (cre
44 which cause hypoalbuminemia, biliary loss of albumin, and increased intracellular accumulation of alb
46 re, kidney weight/body weight ratio, urinary albumin, and urinary thiobarbituric acid-reacting substa
47 the covalent immobilization of bovine serum albumin antibody (anti-BSA) and fibrinogen antibody (ant
48 ucture of PawS1 revealed that SFTI-1 and the albumin are independently folded into well-defined domai
49 agmatic clinical trials of terlipressin with albumin are warranted to evaluate real-world effectivene
55 with an antibody response against the human albumin-based carrier protein, which was prevented by us
58 undiluted serum than Abraxane, a commercial albumin-based PTX nanoparticle formulation, while mainta
59 lbumin recycling and the possibility to tune albumin-based therapeutic effects by FcRn-binding affini
62 supercharging was probed using bovine serum albumin, beta-lactoglobulin, and lysozyme, each of which
64 prognosticators on univariate analysis were albumin, bilirubin, ascites, tumor size 5 cm or smaller,
65 Purpose To construct a nomogram with the albumin-bilirubin (ALBI) grade to assess the long-term o
66 e effect of mono- or divalent small-molecule albumin binders for half-life extension of peptides.
67 the renal excretion kinetic and intrahepatic albumin binding affinity of CyG can further be used to d
69 umor-specific delivery of amphiphile-CpG, an albumin-binding analog of CpG ODN, following systemic ad
71 molecular vaccines with Evans blue (EB) into albumin-binding vaccines (AlbiVax), here we develop clin
72 which lies in Subdomain IIIA of human serum albumin, blocks binding of all three antibodies to nab-p
73 patients resulted in a temporary increase in albumin blood level and symptom improvement in 1 patient
74 R) of imiquimod in combination with systemic albumin bound paclitaxel in treatment-refractory breast
75 emoimmunomodulation with a TLR-7 agonist and albumin bound paclitaxel is effective in inducing diseas
79 A parsimonious mechanism involves leakage of albumin-bound nonesterified fatty acids (NEFAs) across t
83 comprising alternate layers of bovine serum albumin (BSA) and tannic acid (TA) were tested as Lf enc
86 echanism of SA interaction with bovine serum albumin (BSA) has been investigated by multi-spectroscop
87 ration of fluorescently labeled bovine serum albumin (BSA) into the nanoslits; and fluorescence corre
88 ay; LC-MS of a trypsin-digested bovine serum albumin (BSA) sample provided narrow peaks, short dwell
89 patible nanocomposite including bovine serum albumin (BSA) template Cu nanoclusters (CuNCs@BSA) and s
90 nstrated that the adsorption of bovine serum albumin (BSA) to aqueous gold colloids can be quantified
93 lized via EDC-NHS chemistry and Bovine serum albumin (BSA) was used for blocking of the non-specific
94 llowed by a post-treatment with bovine serum albumin (BSA) which served as the blocking agent to prev
95 nhibitor (TI); Ovalbumin (OVA); Bovine Serum Albumin (BSA)), we observe resolution of the markers in
96 red to Y-tube compartments with bovine serum albumin (BSA), GDNF and NGF increased the motor and sens
97 ted gold film and adsorption of bovine serum albumin (BSA), respectively, on poly(methyl methacrylate
103 circuits altering the binding capacities of albumin by biochemical (changing of pH) and physical (ch
104 provides rapid regeneration of toxin-binding albumin by two purification circuits altering the bindin
106 r studies are required to confirm that serum albumin can be used as a biomarker to monitor disease ac
107 ng intranasal house dust mite or aerosol ova-albumin challenge, and chloroquine or quinine were teste
108 m containing Pluronic F-127 then coated with albumin ("Cim-F-alb") had the smallest size and the most
109 o overcome these challenges, we developed an albumin-coated nanocrystal (NC) formulation of paclitaxe
111 osis on initial biopsy as well as age, serum albumin concentration, and CKD stage at onset affected E
113 e mice, and we demonstrate that breakdown of albumin contributes to the supply of free amino acids in
117 ertension (P < 0.001), the increase of urine albumin creatinine ratio (P < 0.01), the fall in glomeru
119 90 mL.min(-1).1.73 m(-2)) and baseline urine albumin-creatinine ratio (>300, 30-</=300, <30 mg/g).
120 nsistent across categories of eGFR and urine albumin-creatinine ratio at baseline and across the 2 do
121 ation rate <60 mL/min per 1.73 m(2) or urine albumin/creatinine >30 mg/g) and available echocardiogra
122 ic acid clearance) was associated with urine albumin/creatinine ratio (UACR) post-HTx in a subgroup o
123 ructural renal lesions, and measured urinary albumin/creatinine ratios, tissue oxidative stress level
124 l attenuated CS-induced increases in urinary albumin/creatinine ratios, tissue oxidative stress level
128 ese properties allow hepatic FcRn to mediate albumin delivery and maintenance in the circulation, but
129 regarding the virulence of P. aeruginosa in albumin-depleted versus albumin-rich infection sites and
130 egies to overcome the pitfall of present day albumin detection methods as well as accelerate the dete
131 anced Organ Support (ADVOS) is a new type of albumin dialysis, that provides rapid regeneration of to
133 inding affinities significantly affected the albumin distribution between late endosomes and lysosome
134 nsely immobilized conjugates of bovine serum albumin (DNP-BSA) or mobile in a supported lipid bilayer
139 ormoalbuminuric or macroalbuminuric (urinary albumin excretion <30 mg/24 hours and >300 mg/24 hours,
140 xture to identify associations between urine albumin excretion (urine albumin-to-creatinine ratio [UA
141 dies have found an association between urine albumin excretion and Amerindian ancestry in Hispanic/La
142 as lost after further adjustment for urinary albumin excretion and eGFR [HR:1.15 (95% CI, 0.81-1.64),
143 nts with type 1 diabetes, rapid increases in albumin excretion during puberty precede the development
145 hesized that adolescents with high levels of albumin excretion might benefit from angiotensin-convert
147 om podocytes exhibited an elevation in urine albumin excretion that was accompanied by increased podo
148 GC-A cKO mice demonstrated increased urinary albumin excretion with marked mesangial expansion, podoc
149 ng-term benefits of empagliflozin on urinary albumin excretion, irrespective of patients' albuminuria
150 duced systolic blood pressure (SBP), urinary albumin excretion, segmental sclerosis, podocyte injury,
151 anoparticle conjugate of paclitaxel to human albumin, exhibits efficacy in pancreatic cancer, non-sma
153 d confirm Evans blue (bound to macromolecule albumin) extravasation, and hematoxylin-eosin staining h
154 aining serum and exosome proteins, including albumin, fetuin-A, apolipoprotein-A1, alkaline phosphata
157 assemble in vivo from AlbiVax and endogenous albumin for efficient vaccine delivery and potent cancer
162 advanced glycation end-product-albumin (AGE-albumin) from activated macrophages is critical in both
163 h as glycated hemoglobin (HbA1c) or glycated albumin (GA) in the blood, are essential indicators of g
165 amascena and Nigella arvensis, including the albumin, globulin, glutein-1, glutein-2 and prolamin fra
168 alized adults in the United States receiving albumin has increased, with marked, and currently unexpl
169 solved diagnostics using specific IgE to 2 S albumins has shown to be a valuable new option in diagno
170 y of measuring plasma creatinine and urinary albumin, has been almost entirely focused on the glomeru
171 post-adsorption of human serum:bovine serum albumin (HS:BSA) mixtures onto the folic acid modified s
176 SMA and appropriate affinity for human serum albumin (HSA) may demonstrate a higher therapeutic index
177 tor of Abeta self-association is human serum albumin (HSA), which binds approximately 90% of plasma A
180 embrane transporters, association with serum albumin in circulatory and extracellular spaces, and ass
181 IR probe (CyG) for precise quantification of albumin in different biofluids and liver targeted in viv
182 include surfactant proteins in lung alveoli, albumin in liver parenchyma, and lipase in the stomach l
183 r visually indistinguishable placebo of 0.1% albumin in saline on days 1 and 22 after randomization.
186 nd increased apparent solute permeability to albumin in the same vessels in a time-dependent manner,
187 cific conclusions regarding the unfolding of albumins in the gas phase, as well as more general infer
189 me and all 17 disulfide bonds in human serum albumin, including nested disulfide bonds and motifs of
192 ce HIF-1alpha level significantly attenuated albumin-induced increases in TIMP-1 and collagen-I level
193 sted the hypothesis that HIF-1alpha mediates albumin-induced profibrotic effect in cultured renal pro
194 s achieved by pharmacologic blockade of FcRn-albumin interactions with monoclonal antibodies or pepti
195 results provide an unprecedented view of how albumin interacts with Abeta and illustrate the potentia
198 e main function of hepatic FcRn is to direct albumin into the circulation, thereby also increasing he
199 erthermia induced a 30-40% increase in Alexa-Albumin into the tumor micro-environment 24 h after trea
200 eneral unfolding pathway of low charge state albumin ions is largely unaffected by changes in primary
204 ociation constant for Zn(2+) and human serum albumin (Kd = (5.62 +/- 0.93) x 10(-7) M) under physiolo
205 sulted in sustained improvement of the serum albumin level and symptoms in 3 patients, temporary impr
206 level than men, and stratification by serum albumin level attenuated sex differences in the age grou
207 eatment with IVIG (2 g/kg), the median serum albumin level decreased to 3.7 g/dL (interquartile range
208 82 g/L (reference range, 66-81 g/L), a serum albumin level of 39.3 g/L (reference range, 40.2-47.6 g/
214 hether there is an association between serum albumin levels, a widely used and relatively easily meas
215 ugation of fatty acid, a natural human serum albumin ligand, to a therapeutic protein/peptide was dev
216 APAP-induced liver injury through increased albumin loss into the bile and increased intracellular a
217 range, 3.8-4.5 g/dL), with hypoalbuminemia (albumin, <3.5 g/dL) in 20 (12.8%) of 156 patients.
221 seconds to hours after injecting gold-tagged albumin, negatively charged gold nanoparticles, and stab
222 5% of model biochemical species (human serum albumin, neurotensin, creatinine, glycine, and alanine)
223 H prediction risk score PANWARDS (platelets, albumin, no congestive heart failure, warfarin, age, rac
224 ide bridging to maintain conformation (e.g., albumins, nonspecific lipid transfer proteins, saposins,
227 with SAH, there is a significant increase in albumin oxidation, and albumin acts as a pro-oxidant; th
230 d to play a central role in maintaining high albumin plasma levels through a cellular recycling pathw
231 estingly, unusual napin-type 2S seed storage albumin precursors in sunflowers contain a sequence that
232 binding of biopharmaceuticals to human serum albumin protects against enzymatic degradation and renal
233 b release from a nanoshell-based human serum albumin protein host complex resulted in increased cance
237 bing fundamental mechanisms of intracellular albumin recycling and the possibility to tune albumin-ba
241 RPS-027 shows dual targeting to PSMA and albumin, resulting in a high tumor uptake, highly favora
243 of P. aeruginosa in albumin-depleted versus albumin-rich infection sites and an understanding of the
244 ositive co-protein effects with bovine serum albumin, (S-)ovalbumin, egg white, whole egg, defatted e
248 ngth of end-stage renal disease, hemoglobin, albumin, selected comorbidities, race and type of insura
255 as superior to both RBC and buffered dextran-albumin solution for extended lung preservation in a swi
256 on (IgPro20) weekly versus placebo (2% human albumin solution) for maintenance treatment for 24 weeks
257 pression of the above-mentioned genes in SAH-albumin-stimulated healthy neutrophils was comparable wi
258 n structures of native-like cations of serum albumin, streptavidin, avidin, and alcohol dehydrogenase
260 e data reveal the immense promise of in situ albumin targeting for development of translational, carr
261 by the selective modification of recombinant albumin that displays 17 structurally relevant disulfide
262 mance status (PS), C-reactive protein (CRP), albumin, the nutritional risk index, daily energy intake
263 ytes in vitro are committed to internalizing albumin through a receptor-mediated mechanism even after
264 ") had the smallest size and the most native albumin, thus showing the most favorable cell interactio
267 iaturized plasma exchange to deliver labeled albumin to tissues in live mice, and we demonstrate that
268 e subgroup of patients with baseline urinary albumin-to-creatinine ratio >/=30 mg/g, urinary albumin-
270 129 mice exhibited a substantial increase in albumin-to-creatinine ratio (ACR) and serum creatinine l
271 associations of creatinine-based eGFR, urine albumin-to-creatinine ratio (ACR), and dipstick proteinu
273 tions between urine albumin excretion (urine albumin-to-creatinine ratio [UACR]) and genomic regions
274 arameters (glomerular filtration rate, urine albumin-to-creatinine ratio and urine protein-to-creatin
275 umin-to-creatinine ratio >/=30 mg/g, urinary albumin-to-creatinine ratio decreased more with canaglif
277 odels for demographics, baseline eGFR, urine albumin-to-creatinine ratio, comorbidity, and measures o
280 d 1287 with values in the upper third of the albumin-to-creatinine ratios; 443 were randomly assigned
281 9.3 g/L (reference range, 40.2-47.6 g/L), an albumin-to-globulin ratio (a test showing relative amoun
282 ment, intracellular pathway, and kinetics of albumin trafficking by flow cytometry, quantitative conf
284 hypothesized that Cav-1 may be critical for albumin uptake in tumors and perhaps determine their res
287 albumin use were appropriate indication for albumin use (odds ratio, 65.220; 95% CI, 62.459-68.103);
291 al changes were induced by the serum protein albumin via TGFbeta signaling in primary astrocytes.
294 e-water distribution coefficients (log Dmw), albumin-water distribution coefficients (log DBSAw), and
295 s inhibited by physiological levels of serum albumin, which appears to bind and sequester some homose
296 g two promising candidate genes AAP8 and 2 S albumin, which might contribute to the high level of WSP
297 like albumin with low FcRn-binding affinity, albumin with high FcRn-binding affinity was directed les
299 binding site, HSA Peptide 40, on human serum albumin with nanomolar affinity for all three monoclonal
300 use of wild-type and engineered recombinant albumins with either decreased or increased FcRn affinit
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