ライフサイエンスコーパス: aldehyde reductase

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1 olar range and high selectivity, relative to aldehyde reductase.

2 , and has high selectivity for aldose versus aldehyde reductase.

3 yme that we designate SCALD, for short-chain aldehyde reductase.

4 stitutive expression of both mouse and human aldehyde reductase.

5 onoamine oxidase, aldehyde dehydrogenase and aldehyde reductase.

6 carboxyl-containing substrate preference of aldehyde reductase.

7 e balance of O2 supply and removal of native aldehyde reductases.

8 , while being 5400 times less active against aldehyde reductase, a related enzyme involved in the det

9 f p-coumaraldehyde, likely the result of low aldehyde reductase activity (i.e. alcohol dehydrogenase

10 ne caused only a minor change in seed pterin aldehyde reductase activity.

11 Pseudomonas putida (mdlC) and native E. coli aldehyde reductase (adhP) in E. coli BL21 star(DE3), the

12 rA- cells, suggesting that the Dictyostelium aldehyde reductase affects several metabolic pathways in

13 PGA1 elicited only marginal inhibition of aldehyde reductase (AKR1A1), considered responsible for

14 nstitutively and widely expressed human AKR, aldehyde reductase (AKR1A1), will oxidize potent proxima

15 e reduction of HNE with higher activity than aldehyde reductase (AKR1A1).

16 nd Arg311, located in the C-terminal loop of aldehyde reductase, and not found in any other C-termina

17 se intermediaries, characteristic of hepatic aldehyde reductases, and to maintain osmoregulation, a f

18 ent in dog retinal capillary pericytes, with aldehyde reductase being the major reductase present.

19 ing mouse gene knock-out models, we identify aldehyde reductase (EC 1.1.1.2, Akr1a4 (GR)) and aldose

20 Aldehyde reductase (EC 1.1.1.2; AKR1A1) is involved in t

21 analyze the mechanism of basal regulation of aldehyde reductase expression, we cloned the murine gene

22 the regulation of its expression, the human aldehyde reductase gene and promoter were cloned and cha

23 In this study, we report a novel aldehyde reductase gene clone Y63 from ethanologenic yea

24 In contrast to the mouse gene, the human aldehyde reductase gene has two alternatively spliced tr

25 Comparison of the aldehyde reductase gene structure to all other character

26 Human aldehyde reductase has a preference for carboxyl group-c

27 At1g10310, previously described as a pterin aldehyde reductase in folate metabolism.

28 Aldehyde reductase is involved in the reductive detoxifi

29 of Arg311 and the anion binding site in the aldehyde reductase molecule.

30 hern blots of multiple tissues indicate that aldehyde reductase mRNA is present in all tissues examin

31 r with the broad-substrate specificity of an aldehyde reductase or an aldehyde decarbonylase, the cat

32 s performed with the 5' probe from the human aldehyde reductase promoter.

33 NADPH-coupled aldehyde reductase reduces a wide variety of aldehydes t

34 find that disrupting alrA, the gene encoding aldehyde reductase, results in the loss of alrA mRNA and

35 peaks corresponding to aldose reductase and aldehyde reductase, the latter being dominant, were obse

36 Aldehyde reductase thus becomes the fourth protein-encod

37 abidopsis gene (At1g10310) encoding a pterin aldehyde reductase was identified by searching the short

38 and comparison with the active site of human aldehyde reductase, whose structure is very similar.

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