ライフサイエンスコーパス: alkyl group

1 ffering in size, polarity, and charge of the alkyl group.

2 d activation of an amine with an unactivated alkyl group.

3 onomers due to the steric requirement of the alkyl group.

4 of CC bond dehydrogenation of an unbranched alkyl group.

5 dily, alpha-protons must be available on the alkyl group.

6 rresponding roughly to the size of the alpha-alkyl group.

7 ne can be tuned by varying the length of the alkyl group.

8 tal alpha-carbon, and (e) branching in the N-alkyl group.

9 the C-C bond to dithiane or to the tertiary alkyl group.

10 vase conformation with self-inclusion of one alkyl group.

11 the beta-carbon, such as an aryl or branched alkyl group.

12 CH2CH2COOH)(OCONHR)], 4, where R is a linear alkyl group.

13 primary amide group from a chemically inert alkyl group.

14 action is undiminished by sterically bulky N-alkyl groups.

15 es contained significant amounts of nonpolar alkyl groups.

16 kyl substituent for both linear and branched alkyl groups.

17 le W138 provides specificity for short-chain alkyl groups.

18 m polar cyano- and nitro- groups to nonpolar alkyl groups.

19 up while dimethylethylammonium only contains alkyl groups.

20 the 6-position can accommodate a variety of alkyl groups.

21 in sp(3) C-H bonds are replaced with sp(3) C-alkyl groups.

22 tive amounts of 1,2- and 1,4-addition of the alkyl groups.

23 hen polyamine length was shortened below six alkyl groups.

24 ed aromatic rings and a limited selection of alkyl groups.

25 -Ti(O-i-Pr)(3) was used as the source of the alkyl groups.

26 igher k(cat) values than those with branched alkyl groups.

27 ulky ortho substituents but also by the para alkyl groups.

28 ubstrates increased 200-fold with the larger alkyl groups.

29 ng variable steric requirements for both the alkyl groups.

30 hexyl and octyl) and branched (2-ethylhexyl) alkyl groups.

31 that contain fluorinated and nonfluorinated alkyl groups.

32 alkyl groups; and (iv) steric demands of the alkyl groups.

33 ading capacities and solubilizing oligoether/alkyl groups.

34 a prototypical substrate bearing two linear alkyl groups.

35 otency decreases with increasing size of the alkyl groups.

36 topology arises when the key atom bears two alkyl groups.

37 uch is known about how the structures of the alkyl group affect the repair and replicative bypass of

38 me, that the size of the heteroatom-attached alkyl group affects the rate of conjugate addition.

39 of LDK1203 and LDK1222 are substituted by an alkyl group and a tosyl group, respectively.

40 imides containing a solubilizing swallowtail alkyl group and a variety of substituted aryl groups can

41 nactivation involves the removal of the O(6)-alkyl group and its transfer to the active-site cysteine

42 R-CH(OH)-(CH(2))(n)-CH(3), where R = H or an alkyl group and n >or= 6.

43 imizing steric interactions between the beta-alkyl group and one of the ligands on boron.

44 ion is selective toward the less-substituted alkyl group and shows moderate to excellent diastereosel

45 to the smaller steric repulsion between the alkyl group and the lithium surface.

46 in which the large substituent is a primary alkyl group and the medium substituent is a methyl group

47 ally friendly chiral racemic semifluorinated alkyl group and with AB3 minidendrons containing the sam

48 ich the carbomethoxy has been replaced by an alkyl group and with different phenyl substituents, have

49 regio- and chemoselective dehydrogenation of alkyl groups and alkanes.

50 g, at the beta'-position, linear or branched alkyl groups and aryl groups.

51 ituents were not tolerated; however, shorter alkyl groups and cyclic alkyls were acceptable.

52 osphate and monophosphonate groups by simple alkyl groups and evolved into the sophisticated ProTide

53 e relationship between the length of pendant alkyl groups and framework stability toward water vapor

54 m one another in the length and branching of alkyl groups and neutralized by different anions.

55 of complexes with chemical bonds between the alkyl groups and the copper complexes.

56 dependent on both the nature of the terminal alkyl groups and the geometry of the methylene spacers s

57 mmetrical dendrons with alternating branched alkyl groups and triarylamine moieties at their peripher

58 ould be minimized with sterically hindered N-alkyl groups), and use of a novel "diamine switch" strat

59 sions decreased with the chain length of the alkyl group, and these lesions directed promiscuous nucl

60 rporation of hydrophobic heterocyclic rings, alkyl groups, and halogens allowed a fine-tuning capabil

61 on current for SAMs terminated in nonpolar n-alkyl groups, and polar groups selected from common pola

62 ive migratory aptitude of phenyl groups over alkyl groups, and provides an efficient synthesis of (+)

63 R and R' are alkyl groups, and the terminal methylene is activated by

64 ) lateral van der Waals interactions between alkyl groups; and (iv) steric demands of the alkyl group

65 determining concerted N(2)-loss/shift of the alkyl group antiperiplanar to the N(2) leaving group.

66 etones with increasing steric demands of the alkyl group are evaluated as potential electrophiles for

67 alpha values for both secondary and tertiary alkyl groups are in the range: alpha = 0.57-0.61.

68 correlation effects between electrons in 1,3-alkyl groups are largely responsible for the enhanced co

69 Poly(N-alkylacrylamide)s with larger N-alkyl groups are predominantly (C(6), 85%; C(7), 95%) or

70 In general, alkyl groups are readily contorted when their internal s

71 T, and NE reuptake, cis isomers with small N-alkyl groups are selective blockers of 5HT reuptake, and

72 , but alkene reactions that form hydrophobic alkyl groups are substantially less favorable in water t

73 ugh U=O and U=NR double bonds (where R is an alkyl group) are well-known analogues to transition-meta

74 Unbranched alkyl groups assume fully extended conformations in the

75 prefers a pseudoequatorial position, and the alkyl group at C-4 has little influence on conformationa

76 Among 8-phenyl analogues, a larger alkyl group at the 1-position than at the 3-position fav

77 The size of the lipophilic alkyl group at the 5-position of the indole has signific

78 ents exist as equilibrating isomers with the alkyl group at the 7-11 or 12 halide positions of the CB

79 uction of a variety of primary and secondary alkyl groups at room temperature.

80 substituted silanes possessing both aryl and alkyl groups at silicon atom were efficiently prepared u

81 thout the stereochemical control provided by alkyl groups at the 1 and 10 positions were isolated as

82 whereas analogs bearing smaller and branched alkyl groups at the 3 position of the oxopiperazine temp

83 uanidine (MNNG) are known to covalently link alkyl groups at the position 6 of guanines (O6MG) in DNA

84 the metal-Calpha-Cbeta-R moiety, in which an alkyl group attached to the Cbeta atom is transferred to

85 ome less important when the bulkiness of the alkyl groups attached to boron increases.

86 the preparation of benzochlorins containing alkyl groups attached to the exocyclic phenyl ring, the

87 Subtle changes in the alkyl groups attached to the thioether sulfur caused dra

88 roviding allylic alcohols bearing almost any alkyl group available using organoborane chemistry and i

89 (n = 5) are ordered and crystalline, and the alkyl groups become increasingly disordered and liquidli

90 rboring seven O(2)-alkyldT lesions, with the alkyl group being a Me, Et, nPr, iPr, nBu, iBu or sBu, a

91 red how eight O(4)-alkyldT lesions, with the alkyl group being a Me, Et, nPr, iPr, nBu, iBu, (R)-sBu

92 Nitrones with alkyl groups bound directly to the 1,3-dipolar moiety fa

93 ture both anancomeric structures, displaying alkyl groups bound to the cyclohexyl ring in equatorial

94 entation of the lithiation relative to the N-alkyl group, (c) the presence or absence of a potentiall

95 The position of the alkyl group (C1) was established by NMR spectroscopy and

96 s the introduction of a variety of perfluoro alkyl groups (C1-C10) and a CF2COOEt moiety.

97 In the resulting structures, long chain alkyl groups (C12 and C14) and phosphopantetheinate defi

98 Methyl, primary, and secondary alkyl groups can all be coupled in good yield (77% ave y

99 Primary and secondary alkyl groups can be installed.

100 ylides (i.e. those bearing only hydrogens or alkyl groups) can be generated from (2-azaallyl)stannane

101 electron-donating groups such as amides and alkyl groups cause a decrease.

102 to a weakening of the bonds to the bridging alkyl groups; CCG is thus usually more favored for steri

103 inyl, acyl, methyl, and other functionalized alkyl groups chemoselectively to a wide variety of unact

104 ex that isomerizes if necessary to place the alkyl group cis to the boryl group.

105 yield as single diastereomers having the C-2 alkyl group cis to the C-4 carboxylic ester.

106 ude by the introduction of a 10-methoxy or 7-alkyl group compared with camptothecin.

107 ue and reports that 3'-n-propyl and longer n-alkyl groups conferred RXR antagonism.

108 servation that ketones with sterically bulky alkyl groups could be reduced to the corresponding alcoh

109 otentially chelating methoxy moiety on the N-alkyl group, (d) the presence of a 2-methyl substituent

110 2-alkylimidazoline 24 is proposed, where the alkyl group derives from the substrate; this imidazoline

111 The size and shape of the N-alkyl group dramatically changed the potency of the tria

112 y to anti (17a and 17b) by introducing bulky alkyl groups (e.g., propyl groups) onto the hydroxy grou

113 pallidols) (both or one ring substituted by alkyl groups, e.g., 4,4'-dimethylstilbene); and those wh

114 stitution at the C-5 position of cytosine by alkyl groups (ethyl and methyl) markedly enhanced the dC

115 lic substituents (o-, m-, p-pyridyl) or four alkyl groups (ethyl, propyl, butyl, pentyl), in which ca

116 Alkyl groups favor equatorial positions in the oxocarben

117 We report that alkyl group fluorination (e.g., CB[7].1-AdNH2Et versus C

118 Coadsorption of hydrogen and alkyl groups, followed by heating of the surface, result

119 e substituents (i.e., chlorines for PCBs and alkyl groups for alkylated-PAHs) to the molecular struct

120 ltransferase (AGT), which transfers the O(6)-alkyl group from the damaged base to a cysteine residue

121 adducts of AChE that result from loss of one alkyl group from the inhibited enzyme (the aging reactio

122 AGT proteins remove methyl and other alkyl groups from an alkylated O(6) in guanine by transf

123 ough the inner-sphere attack of nucleophilic alkyl groups from magnesium to the reacting carbons via

124 The DNA and RNA repair protein AlkB removes alkyl groups from nucleic acids by a unique iron- and al

125 Rates of individual steps in the removal of alkyl groups from O6-methyl (Me) and -benzyl (Bz) guanin

126 ylguanine-DNA methyltransferases to transfer alkyl groups from other lesions onto a cysteine residue.

127 ant headgroups, counterions, water, and some alkyl groups from the hydrophobic tails.

128 other O(6)-alkylguanine lesions by removing alkyl groups from the O(6)-position.

129 (AGT) is a DNA repair protein which removes alkyl groups from the O-6 position of guanine, thereby p

130 even when they contain stereocenters on the alkyl groups from their periphery.

131 ap that promotes exchange of an acyl with an alkyl group, generating the characteristic ether bond.

132 hydroxy-s-triazines, and those with linear N-alkyl groups had higher k(cat) values than those with br

133 l ketones, ArC(O)R, with a diverse number of alkyl groups have been achieved with an isolated carbony

134 c bulk around nitrogen (by changing the tert-alkyl group) have been prepared and examined as borane c

135 ting copper-rich species have less polarized alkyl groups, i.e. gradually reduced reactivities.

136 dly, flips O6-alkylG residues, transfers the alkyl group in a chemical step that is rate-limiting in

137 effectively distinguish between a CF3 and an alkyl group in order to provide good ee.

138 migrate less effectively than other types of alkyl group in such reactions and that O-migration compe

139 As the alkyl group in the RTIL was elongated, the K+/ Rb+ and K

140 han the hydrophobic interactions between the alkyl group in the thioether tail and surrounding protei

141 Positional disorder of the alkyl group in the X-ray structure of 4 corresponds to p

142 what are generally considered to be "remote" alkyl groups in -CbetaH=CalphaHS(O)n-alkyl systems and -

143 e-tree columns that allow interdigitation of alkyl groups in adjacent columns regardless of their dir

144 Larger N-alkyl groups in both the trans and cis series were found

145 aldehyde acetals with secondary and tertiary alkyl groups in contrast to specific hydrogen catalysis

146 alkyl zincates and show the relevance of the alkyl groups in the efficiency of TMP-dialkyl zincate ba

147 polarizability substituent constants of the alkyl groups in the form of a linear free energy relatio

148 ckets differ in their ability to accommodate alkyl groups in the indole nitrogen region of the melato

149 The alkyl groups in the study are ethyl, n-propyl, n-butyl,

150 Molecular modeling clearly shows that the alkyl groups in these Michael acceptors shield the beta-

151 rs does not suffer from isomerization of the alkyl group, in contrast with the umpolung strategy for

152 rimary amine with an alpha-chiral tertiary N-alkyl group, in very good yields.

153 ield and the polarizability constants of the alkyl groups increases the value of DeltaE(H)(double dag

154 occur with retention of configuration at the alkyl group, indicating that these reductive elimination

155 of the rotational isomers for the less bulky alkyl groups, indicating that the observed preference is

156 rmediates by trapping with TEMPO or CO or by alkyl group interchange with an excess of an alkyl halid

157 n of imide and amide bonds with a long-chain alkyl group is an attractive feature of this protocol.

158 Surprisingly, when the terminal end of the alkyl group is completely fluorinated, the balance tips

159 ter charge on the number-2 carbon unless the alkyl group is electron withdrawing.

160 2.0-7.4) and rabbit serum; furthermore, the alkyl group is possibly tuned to attain the desired phar

161 lsulfonyl-2'-biphenyl radicals, in which the alkyl group is primary, secondary, or tertiary, were gen

162 dimethyl(ferrocenylmethyl)ammonium ions (the alkyl group is propyl for compound 1, heptyl for 2, dode

163 gal genealogy) and the chirality of the C-24 alkyl group is similar in the two nonphotosynthetic micr

164 The alkyl group is the most common component of organic mole

165 erature ionic liquids (RTILs) in which the 1-alkyl group is varied systematically from butyl to nonyl

166 der for N-alkyl aza-18-crown-6, in which the alkyl group is varied systematically from ethyl to n-dod

167 detailed structure of the attachment of the alkyl groups is not known, and it is proposed that it in

168 helicene inner rim and multiple solubilizing alkyl groups, is an attractive building block for long [

169 creased, the increased steric demands of the alkyl groups lead to liquidlike, disorganized alkyl laye

170 he benzimidazole ring, especially with small alkyl groups, led to dramatic increases in potency, both

171 ility that, under appropriate circumstances, alkyl groups may undergo transfer from alkyl sulfate mon

172 e chain, combined with the presence of small alkyl groups (methyl or ethyl), bromine, or aryl moietie

173 ons and experimental evidence show that tert-alkyl groups migrate less effectively than other types o

174 g 3-alkoxy-2-halocyclohex-2-enones via a 1,4 alkyl group migration shown to be concerted and intramol

175 The second or alkyl group migration step has a much reduced activation

176 de both the addition step and the subsequent alkyl group migration step included ketones, acetone, t-

177 lex which breaks down in a rate-limiting 1,2-alkyl group migration with concomitant expulsion of a mo

178 opening, C-C bond rotation, and hydrogen or alkyl group migration) are required in any path.

179 e C-F bond to the OBF2 group and hydrogen or alkyl group migration, as first demonstrated in this wor

180 atures (solvent effects, concurrent hydrogen/alkyl group migration, carbocation substitution, benzyli

181 l into the alpha- and omega-positions of the alkyl group monitored by (2)H NMR spectroscopy.

182 ene depends strongly on the structure of the alkyl group: n-alkyl approximately gamma-substituted >>

183 L1 was able to catalyze removal of different alkyl groups not only from N(6)-substituted purine or 2-

184 ophilicity, the presence and position of the alkyl groups (O-alkyl vs N-alkyl) in a molecule play an

185 (wherein R could be methyl, ethyl, aryl, or alkyl group) obtained from synthetic procedures, and a s

186 lly slow migration of the beta-disubstituted alkyl group of 6 and not to differences in the equilibri

187 ing pantetheinate arm and the second for the alkyl group of one substrate.

188 bstituent of the substrate and the N-aryl or alkyl group of the ketone catalyst.

189 kylated species, arising by migration of the alkyl group of the N-alkyl moiety to the adjacent ring c

190 the halogenase SyrB2 that positioning of the alkyl group of the substrate away from the oxo/hydroxo l

191 t is suggested that the rearrangement of the alkyl group of thebaine is favored due to the formation

192 alpha-methylene carbon of 2-nitrobenzyl with alkyl groups of increasing size was discovered as a key

193 tution of the oxatriquinane ring system with alkyl groups of increasing steric demand pushes the C-O

194 e closely related area of dehydrogenation of alkyl groups of substrates containing heteroatoms.

195 enter that can be incorporated either in the alkyl groups of the dendron or in the triphenylene part

196 esents the number of methylenic units in the alkyl groups of the dendron, are reported.

197 that results from the interdigitation of the alkyl groups of the Janus dendrimer.

198 ity relationship study revealed that a small alkyl group on the alpha-position of the ether was requi

199 We report here the use of a 2-alkyl group on the imidazolo[1,2-a]pyrimidone core to ge

200 ion is slightly cationic with respect to the alkyl group on the Pt(111) surface, RC + H <--> {RC(delt

201 depend exclusively on the steric bulk of the alkyl group on the starting Michael acceptor.

202 Alternatively, an alkyl group on the terminus of the allene undergoes cycl

203 The stabilizing and destabilizing effects of alkyl groups on an aromatic stacking interaction were ex

204 onstrates that, while the steric effect of o-alkyl groups on aryl substituents is highly localized to

205 ar columnar structure containing fluorinated alkyl groups on its periphery.

206 e strands by 29.5 to 37.4 kcal/mol; (2) that alkyl groups on the amino acid side chains favor helix f

207 of the transition state to hydrogenation of alkyl groups on the Pt(111) surface.

208 urther, we have correlated the effect of the alkyl groups on the structural order and orientation of

209 ibuted to nonbonded interactions between the alkyl groups on the substrates and the aryl groups of th

210 a larger cross-linking strategy, we appended alkyl groups onto the N2' position of 2'-amino-modified

211 intramolecular hydrogen abstraction from the alkyl group or addition to the solvent, benzene.

212 hydroxyethyl-guanine but does not remove the alkyl group or base and does not cleave the oligonucleot

213 using compounds bearing pyrenemethyl esters, alkyl groups, or a single pyrene substituent (3-6).

214 At higher concentrations, with longer N-alkyl groups, or in selected solvents, electronic excita

215 nsitivity, we installed an electron-donating alkyl group ortho to each phenol group.

216 selective functionalization of the tertiary alkyl group over primary and secondary C-H bonds.

217 ve differently, leading to detachment of the alkyl groups over the temperature range 180-500 degrees

218 In a trialkylaluminum reagent, 1.1-1.4 alkyl groups per Al can be used to replace C-F bonds.

219 The bound alkyl groups point either into the back of the distal po

220 ger), which are dependent on the size of the alkyl group (polarizability) and the degree of fluorinat

221 in 78-98% yield depending on the halogen and alkyl group present.

222 y is ascribed to an inhibitory effect of the alkyl group projecting into the minor groove of double-s

223 lectivity of the reactions was high when the alkyl group R(2) was tertiary (tert-butyl), irrespective

224 , in which the steric difference between the alkyl groups R(1) and R(2) is sufficient.

225 d in one thiolate, transfer of the resulting alkyl group (R') to another thiolate, and subsequent eli

226 (independently) controlled by choice of the alkyl group (R).

227 eferentially antiperiplanar to the migrating alkyl group rather than the aryl group.

228 a weaker, less specific interaction involves alkyl groups reaching into the broad prime-side protein

229 lts explain the overall patterns of rates of alkyl group removal versus AGT concentration and the eff

230 the benzo ring C, as well as H, methoxy, and alkyl groups replacing the hydroxyl group were synthesiz

231 F pretreatment was detected in soils where O-alkyl groups represented the major fraction of the soil

232 cs via attachment of a steroid or long chain alkyl group resulted in compounds with significantly imp

233 roperties of 1-methyladenine; removal of the alkyl group results in a >10-fold light-up signal.

234 more, the possibility of a [1,5] sigmatropic alkyl group shift of bicyclo[4.2.0]octa-2,4-diene system

235 iradical-mediated stepwise [1,5] sigmatropic alkyl group shift were shown to be comparable with the r

236 s were prepared to examine the effect of the alkyl group size, sulfur oxidation state, and phenyl rin

237 To probe the effect of minimizing the alkyl-group size on the chemistry of IPA/NO, we prepared

238 With a large alkyl group substituent, the vibrational energy of the a

239 Simple benzyl and other alkyl groups successfully activated the challenging pyri

240 However, the introduction of small alkyl groups, such as methyl, by this method has not bee

241 y was gained by replacing the ribose with an alkyl group that formed van der Waals interactions with

242 to an aromatic ring, a benzylic group, or an alkyl group that possesses a tertiary or quaternary carb

243 undertaken to determine the conformations of alkyl groups that are forced into small spaces.

244 e work is isonitriles bearing perfluorinated alkyl groups that enable the ready separation of such re

245 the size of the alkyl group, the smaller the alkyl group the greater the exothermicity.

246 hium surface is dependent on the size of the alkyl group, the smaller the alkyl group the greater the

247 Due to the presence of two alkyl groups, the metal-occupied d orbitals (particularl

248 This complex with cis boryl and alkyl groups then undergoes B-C bond formation by a seco

249 t dioxygenase superfamily, which removes the alkyl group through oxidation eliminating a methyl group

250 The rate of migration of an alkyl group to a coordinated alkene depends strongly on

251 alkyltransferases (MGMT) by transfer of the alkyl group to a cysteine residue in the active site.

252 ises from nucleophilic displacement at the O-alkyl group to afford the terminally functionalized N-su

253 out this repair reaction by transferring the alkyl group to an active site cysteine and in doing so d

254 ering from the circulation is removal of the alkyl group to generate an intermediate that can subsequ

255 The alkyltransferase removes the alkyl group to one of its own cysteine residues.

256 but removal of one amidine or addition of an alkyl group to the amidine strongly inhibited dimer form

257 he role of the dialkylzinc is not to add the alkyl group to the carbonyl but rather to transfer the a

258 ing of the epoxy bridge with transfer of one alkyl group to the intermediate cycloadduct.

259 nism involves transfer of hydrogen from an N-alkyl group to the keto oxygen to produce zwitterionic i

260 nism involves transfer of hydrogen from an N-alkyl group to the keto oxygen to produce zwitterionic i

261 one methylene group of phenacetin from the O-alkyl group to the N-acyl moiety increased rates of both

262 p to the carbonyl but rather to transfer the alkyl group to titanium.

263 The asymmetric addition of alkyl groups to aldehydes catalyzed by BINOLate-titanium

264 nsformations, including addition of aryl and alkyl groups to alpha,beta-unsaturated ketones and hydro

265 -1-ol (5), a Z-selective cuprate addition of alkyl groups to an alpha,beta-alkynyl ester intermediate

266 ine activators in the asymmetric addition of alkyl groups to benzaldehyde, we have observed enantiome

267 agent allows effective conjugate delivery of alkyl groups to cyclic and acyclic alkenenitriles.

268 the surface, results in hydrogenation of the alkyl groups to form alkanes, which then desorb into the

269 elopment of catalysts for dehydrogenation of alkyl groups to give the corresponding olefins could ope

270 challenge because of the propensity of these alkyl groups to isomerize under the reaction conditions.

271 mmetric addition of alkyl and functionalized alkyl groups to ketones under highly concentrated and so

272 cleophilic addition of propargylic and other alkyl groups to ketones, using easily accessible (poly)u

273 NA equilibrium binding molecules to transfer alkyl groups to specific positions on DNA is an approach

274 relationship studies revealed that attaching alkyl groups to the cyclohexyl ring significantly improv

275 Alkyllithium reagents may be used to attach alkyl groups to the sidewalls of fluoro nanotubes.

276 on, formally a 1,5 hydrogen shift from the N-alkyl groups to the vinyl position of a gold-coordinated

277 enabling technology for the mild transfer of alkyl groups to transition metal catalysts in cross-coup

278 rve as a competent replacement for Zn(II) in alkyl group transfer enzymes, turnover may be limited by

279 e studied, and CH-insertion into an adjacent alkyl group was found to be the dominant or exclusive pa

280 generally diminished as the length of the 1-alkyl group was increased.

281 h an excess of an alkyl halide of a distinct alkyl group were unsuccessful over a time scale comparab

282 tions of the small meta-alkyl and large para-alkyl groups were due to their similar distances and van

283 ms with different numbers of methyl and long alkyl groups were examined as positively charged heparin

284 Thus, combinations of various alkyl groups were generally inactive at the D(3) recepto

285 trapeptides that possessed greater than nine alkyl groups were superior to alpha-MSH in terms of the

286 Balances with deuterated and non-deuterated alkyl groups were synthesized, and their intramolecular

287 ly, at the farther para-position, the larger alkyl groups were systematically more stabilizing with t

288 and tBu) and position (meta and para) of the alkyl groups were varied in a molecular balance model sy

289 The resultant surfaces, depending on the alkyl group, were able to kill up to 94 +/- 4% of Staphy

290 d substrates, such as those bearing tertiary alkyl groups, were additions slower.

291 t (as well as an aldehyde derived from the O-alkyl group), whereas O-tert-butyl acetophenone oxime (4

292 r ion group can be prepared from halogenated alkyl groups which are also employed for the mass balanc

293 tivity depended on the length of the linking alkyl group, which could be replaced by a poly(ethylene

294 bonyl oxides with the syn-positioned methyl (alkyl) group, which is more favorable than isomerization

295 ing the H-transfer steps during reactions of alkyl groups with CO* to form longer-chain alkylidynes a

296 at the lipophilicities of perfluoroalkyl and alkyl groups with the same length are nearly identical a

297 e insensitive to the replacement of terminal alkyl groups with the terminal polar groups in this set.

298 ctra indicate slowed internal motions of the alkyl groups within the space.

299 ions, those forming a C-N bond at a tertiary alkyl group would be particularly valuable, because this

300 were examined using different sources of the alkyl group [ZnMe(2) or MeTi(O-i-Pr)(3)].