1 (e.g. oxidatively damaged, UV-irradiated, or alkylated DNA).

2 s predicted to catalyze the direct repair of alkylated DNA.

3 s in a conserved mechanism of ATL binding to alkylated DNA.

4 egulating MGMT homeostasis and DNA repair of alkylated DNA adducts in cells.

5 e than with a stable A.T base pair to create alkylated DNA adducts that can be removed by alkyladenin

6 inactivation and are active in the repair of alkylated DNA adducts.

7 A alkyltransferases (AGTs) that tightly bind alkylated DNA and shunt the damaged DNA into the nucleot

8 otide and amino acid biosynthesis, repair of alkylated DNA and the synthesis of mechanosensitive ion

9 nd that it plays a crucial role in reverting alkylated DNA base lesions and cytotoxicity.

10 e importance of this amino acid in repair of alkylated DNA by AGT was studied by changing it to pheny

11 of antibiotics in microbes, and in repair of alkylated DNA in both.

12 rovide new important insights into how these alkylated DNA lesions compromise the flow of genetic inf

13                                    Among the alkylated DNA lesions, O(4)-alkylthymidine (O(4)-alkyldT

14 n discrimination using alkylated dNTP versus alkylated DNA template substrates and the pol beta varia

15 h structural results reveal that ATLs sculpt alkylated DNA to create a genetic and structural interse

16 ne (3MeA) DNA glycosylases remove 3MeAs from alkylated DNA to initiate the base excision repair pathw

17  oxidatively damaged DNA, UV-irradiated DNA, alkylated DNA, uracil-substituted DNA, mismatched DNA, g