ライフサイエンスコーパス: alkyne

1 er [3 + 2] cycloaddition of the azide on the alkyne.

2 ty was achieved in the case of unsymmetrical alkynes.

3 for a broad range of aryl and alkyl terminal alkynes.

4 several different alkyl and aryl substituted alkynes.

5 c hydrophosphination of unactivated internal alkynes.

6 xhibit remarkable reactivity toward terminal alkynes.

7 tion of terminal and functionalized internal alkynes.

8 ization and cycloisomerization starting from alkynes.

9 he selective CuAAC reaction of less reactive alkynes.

10 such as C-H borylation and hydrogenation of alkynes.

11 tions in the presence of various alkenes and alkynes.

12 ve for the hydrogenation of a broad range of alkynes.

13 tes organozirconocenes only from alkenes and alkynes.

14 ibosome interactions caused by the different alkynes.

15 ree -NH2 group of pyrazoles and -OH group of alkynes.

16 northodox trans-hydrometalations of internal alkynes.

17 ambient conditions in one pot/one step from alkynes.

18 e 1-bromo-2-isopropenylbenzenes and internal alkynes.

19 he regioselectivity in reactions of internal alkynes.

20 Instead, in this study, alkyne 1,2-hydrocarbation proceeds by a novel mechanism

21 ation as operates in the only other reported alkyne 1,2-hydrocarbation reaction.

22 ir (FLP) chemistry enables a rare example of alkyne 1,2-hydrocarbation with N-methylacridinium salts

23 FLP acting as a hydride shuttle that enables alkyne 1,2-hydrocarbation.

24 ugation, a hydrophilic spacer, and either an alkyne (6), triazole (7), or piperazine (8) link to the

25 nate as urea precursor and Ag(I) catalyst as alkyne activating agent.

26 te being less electrophilic than other known alkyne-activating reagents and then providing chloride f

27 ed a rate-determining AdE3 mechanism wherein alkyne activation by neutral ClBcat is concerted with cy

28 electivity (up to 85% ee) for a simple alkyl alkyne addition to the N-(diphenylphosphinoyl)imines.

29 ion exploiting a Micalizio alkoxide-directed alkyne-alkene coupling tactic.

30 oms, O((3)P), with unsaturated hydrocarbons (alkynes, alkenes, dienes).

31 onditions, we show that the side reaction is alkyne-alkyne (i.e., Glaser) coupling.

32 A unique intramolecular Pd-catalyzed alkyne-alkyne coupling is presented.

33 ative (Z)-beta-iodoenol esters with terminal alkynes, alkynols, and 1,3-enynes allowed also the acces

34 The alkyne-allene isomerization involves not only a torsiona

35 groups-from amines and halides to arenes and alkynes-along with their air and moisture stability, has

36 ylic amines via the Cu(I)-catalyzed aldehyde-alkyne-amine reactions (A(3) coupling) was accomplished.

37 groups (halides, boronic acids, alkenes, and alkynes, among other groups) but carried inactive substi

38 nt on the remote terminus of the diynophilic alkyne and (ii) an analogous series of dienophilic alkyn

39 ed coupling between an advanced intermediate alkyne and a Weinreb amide to complete the C1-C13 alkyl

40 gh sequential hydroazidation of the terminal alkyne and addition of a sulfonyl radical to the resulta

41 ith a range of symmetrical and unsymmetrical alkyne and alkene dipolarophiles to afford densely subst

42 ole upon cycloaddition within the gorge from alkyne and azide reactants bound at the two sites, respe

43 ted by orthogonal transformation of both the alkyne and boronic ester functionalities.

44 Alkyne and diazoketone coupling partners give azolopyrid

45 The scope of the alkyne and hydrosilane partners is substantial, providin

46 ed: first hydrocarbonylative coupling of the alkyne and the alkyl iodide, followed by reduction of th

47 ilver(I) chiral phosphate activates both the alkyne and the indole nucleophile in the initial cycliza

48 aphenylmethane derivative bearing a terminal alkyne and three triazene moieties.

49 I)-catalyzed [2+2] cycloaddition of terminal alkynes and alkenes has been achieved using non-C2-chira

50 ts for [3+2] cycloaddition reactions between alkynes and azides (i.e., "Click" reactions) at room tem

51 Here, we use the click reaction between alkynes and azides as an example where improvements at t

52 Reaction of cyclic secondary amines with 1-alkynes and copper(I) chloride at 110-120 degrees C give

53 ese multicomponent reactions couple alkenes, alkynes and diazenes to form either alpha,beta-unsaturat

54 most important features of carbocupration of alkynes and highlight the most relevant reviews.

55 s catalyze the cycloaddition of two terminal alkynes and one cyanamide.

56 of aryl boronic acids together with terminal alkynes and perfluoroalkyl iodides in the presence of ca

57 sents a formal hydroacylation of alkenes and alkynes and provides chromanol derivatives in good yield

58 f-activating catalyst in reactions involving alkynes and readily mediates both enyne cyclization and

59 surfaces to give the corresponding terminal alkynes and silyl esters, which is supported by density

60 he cooperative relationship of the aldehyde, alkyne, and ligand in influencing enantioselectivity.

61 ree-component coupling of C(sp(2) )-H bonds, alkynes, and halogenating agents to give alkenyl halides

62 kenylation with olefins, hydroarylation with alkynes, and iodination with N-iodosuccinimide is report

63 fficient one-pot annulation of arylidenones, alkynes, and nitriles in the presence of BF3.OEt2 is des

64 ha-functional groups, as well as alkenes and alkynes, and rapid access to diverse sterically hindered

65 new organometallic aryl-Co(III) compounds in alkyne annulation reactions are also disclosed.

66 taining a Z-allylic phosphate tethered to an alkyne are described.

67 evels of regioselectivity when unsymmetrical alkynes are used that carry an -OH or -NHR group in vici

68 toichiometric by-products, the recent use of alkynes as allylmetal precursors enables completely atom

69 a dipeptide gelator decorated with azide and alkyne at its termini, N3-Ala-Val-NHCH2-C identical with

70 making them convenient, green catalysts for alkyne-azide "click" reactions in water.

71 ature is the cucurbit[6]uril (CB6) catalysed alkyne-azide cycloaddition (CB-AAC).

72 nation of oxime ligation and strain promoted alkyne-azide cycloaddition.

73 popular example so far being strain-promoted alkyne-azide cycloadditions.

74 he designed protocol was well implemented on alkynes bearing long alkyl chain, an alicyclic ring, hyd

75 .5 nm) and soluble GNRs using a nonoxidative alkyne benzannulation strategy promoted by Bronsted acid

76 ALDI matrix molecules), pi-ligands (alkenes, alkynes, benzene, and substituted benzenes), miscellaneo

77 pin and conformational dynamics in symmetric alkyne-bridged multi[copper(II) porphyrin] structures ha

78 Comparison of ethyne and butadiyne alkyne bridges reveals remarkable sensitivity to orbital

79 from dual activation of the pendant terminal alkyne by silver(I) and the ketone moiety through transi

80 Hydroarylation of internal alkynes by cost-effective Co(III)-catalysis, directed by

81 utilizes alkenes as synthetic equivalents of alkynes by coupling homoallylic ring expansion to yield

82 This chemistry provides a way to transform alkynes by splitting the substrate into three parts.

83 alkenylation of arenes and heteroarenes with alkynes by transition metal catalyzed reactions, Bronste

84 rrespondingly broad selection of alkenes and alkynes can be employed.

85 cope, and both symmetrical and unsymmetrical alkynes can be harnessed.

86 nstrate that the hydroallylation of internal alkynes can be used in the regio- and diastereoselective

87 koxy quinolines via an oxonium ion triggered alkyne carboamination sequence involving C-C and C-N bon

88 he sp to sp(2) rehybridization of one of the alkyne carbon atoms.

89 -mediated annulation chemistry where initial alkyne-carbonyl coupling is followed by a second, now in

90 r intramolecular oxidative carboamination of alkynes catalyzed by [py2TiCl2NPh]2 is reported.

91 inc, and propargylamine intermediates from 1-alkynes, chiral (S)-diphenyl(pyrrolidin-2-yl)methanol, a

92 emoselectivity in the copper-catalyzed azide-alkyne click (CuAAC) reaction.

93 We report a new type of azide-alkyne click chemistry for the synthesis of protein conj

94 nnected to functional molecules via an azide-alkyne click reaction.

95 cyclopropane rearrangement is enhanced by an alkyne-Co2(CO)6 complex bonded to the para position of a

96 rization of hitherto hypothetical Au(III) pi-alkyne complexes is reported.

97 different stabilities between the classical alkyne complexes of Pt(II) and their drastically more re

98 icient [2 + 2 + 1] cycloaddition of dicobalt alkyne complexes with alkenes.

99 cation (FLI) tag that can be attached to any alkyne-containing ligand via Cu(I)-catalyzed cycloadditi

100 The FLI tag was coupled to an alkyne-containing neurosteroid photolabeling reagent and

101 ibrations in Raman-silent region compared to alkyne-containing small molecules.

102 The activation of alkyne-containing substrates with B(C6 F5 )3 enabled the

103 isplays a broad scope of carboxylic acid and alkyne coupling partners, and can tolerate an array of f

104 ex fragments utilizing a Ru-catalyzed alkene-alkyne coupling.

105 Alkyne cross-metathesis of molybdenum carbyne complex [T

106 hiral peropyrenes were formed after a 4-fold alkyne cyclization reaction promoted by triflic acid.

107 The copper-catalyzed azide-alkyne cycloaddition (CuAAC) reaction has proven to be a

108 of orthogonal sequential Cu-catalyzed azide-alkyne cycloaddition (CuAAC) reactions is reported.

109 audinger ligation and copper catalyzed azide alkyne cycloaddition (CuAAC) reactions to synthesize het

110 Post-DNA synthesis copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions with a variety of

111 etallic mechanism for copper-catalyzed azide-alkyne cycloaddition (CuAAC).

112 omers via solid-phase copper-catalysed azide-alkyne cycloaddition (SP-CuAAC) click reactions.

113 degrees C resulted in the topochemical azide-alkyne cycloaddition (TAAC) polymerization to 1,4-triazo

114 enylalanine to Uox and strain-promoted azide-alkyne cycloaddition allowed the conjugation of fatty ac

115 Subsequent strain-promoted azide-alkyne cycloaddition allows conjugation of dyes and imag

116 protein shell through strain-promoted azide-alkyne cycloaddition and spontaneous concentration of th

117 CB6-promoted azide-alkyne cycloaddition has been previously used for the sy

118 Azide-alkyne cycloaddition is a powerful reaction for the form

119 hat is followed by the Cu(I)-catalyzed azide-alkyne cycloaddition ligation and by biomimetic formatio

120 eveloped chain-growth copper-catalyzed azide-alkyne cycloaddition polymerization, two structural para

121 pyrazole core through highly regioselective alkyne cycloaddition reactions of sydnones.

122 ed in conjunction with strain-promoted azide-alkyne cycloaddition to generate distinct bioconjugates

123 - 3.3 pmol.cm(-2), and copper-mediated azide-alkyne cycloaddition was used to attach a small molecule

124 don reassignment, and copper-catalyzed azide-alkyne cycloaddition, we can overcome these challenges f

125 s was demonstrated by copper-catalyzed azide-alkyne cycloaddition, with 1,3,5-triethynylbenzene, form

126 competent to undergo a strain-promoted azide-alkyne cycloaddition.

127 tion modification via copper-catalyzed azide-alkyne cyloaddition was enabled by the inclusion of term

128 tion proceeds by a novel mechanism involving alkyne dehydrocarbation with a carbon Lewis acid based F

129 ssfully conjugated with Alexa Fluor 488 DIBO alkyne, demonstrating that this approach is generally ap

130 A novel bis-alkyne-dependent [2+2+2] cycloaddition is proposed as a

131 port a kinetic and spectroscopic analysis of alkyne-dependent chemoselectivity in the copper-catalyze

132 nctional role by sequentially activating the alkyne, despite being less electrophilic than other know

133 allylation and a nickel-catalyzed variant of alkyne diarylation.

134 t elevated temperatures, and the use of aryl alkyne dipolarphiles under catalyst-free conditions.

135 derivatives equipped with clickable (azide, alkyne, double bond, or thiol precursor) moieties, start

136 ation of a vinyl cation from arylglyoxal and alkyne, electrophilic addition of the vinyl cation to th

137 c substrates bind more tightly than ordinary alkynes; even the electronically coupled triple bonds of

138 y the addition of an arylboronic acid to the alkyne, followed by cyclization of the resulting alkenyl

139 -catalyzed additions of arylboronic acids to alkynes, followed by enantioselective cyclizations of th

140 as been achieved through aminopalladation of alkynes, followed by intramolecular nucleophilic additio

141 different kinetic behavior (zeroth order in alkyne for MoF9 derivatives instead of first order for t

142 d for the synthesis of terminal and internal alkynes from the nickel-catalyzed decarboxylative coupli

143 method that affords terminal and substituted alkynes from various carboxylic acids is described using

144 hout the need for a protecting group for the alkyne-functional initiator: (1) maintaining low tempera

145 Alkyne-functional polymers synthesized by ATRP exhibit b

146 el chemical probe of DMF by incorporating an alkyne functionality and found that DMF covalently modif

147 ates having aryl or heteroaryl groups on the alkyne functionality fruitfully participated in the one-

148 The alkyne functionality of the intermediate boronate comple

149 -like geometry, incorporating two juxtaposed alkyne functions, has been synthesized.

150 gand, the reaction tolerates a wide range of alkynes furnishing the products in high yields and excel

151 various SNO-OCTs significantly affected the alkyne geometries, thus illustrating a new strategy for

152 an ynone, modified Stryker reduction of the alkyne, global deprotection, and oxidation of the result

153 ) state decays back to the planar and linear alkyne ground state on a time scale decreasing from a fe

154 ith three stereogenic centers and a terminal alkyne group in one operation.

155 mining cyclization of the hydrazone onto the alkyne group.

156 ion was enabled by the inclusion of terminal alkyne groups in these monomers.

157 lkyne signals result from the integration of alkyne groups into the rigid backbone and the delocalize

158 enters enables introduction of an orthogonal alkyne handle into monoclonal or polyclonal antibodies f

159 nnulation of 2H-chromene-3-carboxamides with alkynes has been achieved by using the directing group n

160 mploying an oxidative Glaser-Hay coupling of alkynes has been applied toward the synthesis of the mac

161 des, a novel class of double aza-substituted alkyne, has been established by the copper(I)-catalyzed

162 eductive coupling reactions of aldehydes and alkynes have been developed.

163 Alkynes have found widespread applications in synthetic

164 A(3) couplings and C-H functionalization of alkynes, have been described and organized on the basis

165 dentical withN(OAr), along with the terminal alkyne HC identical withCR.

166 Glaser coupling can also occur for alkynes held under CuAAC reaction conditions but again c

167 Arrays of nucleophiles including olefins, alkynes, heterocycles, and epoxides are competent traps

168 In particular, we show that the azide-alkyne Huisgen cycloaddition reaction catalyzed by coppe

169 s for Rh-catalyzed intermolecular alkene and alkyne hydroacylation reactions.

170 Using this method, we discovered an alkyne hydroallylation and a nickel-catalyzed variant of

171 ollowed by an intramolecular Au(I)-catalyzed alkyne hydroamination and enamine reduction.

172 in an efficient manner by rhodium-catalyzed alkyne hydroboration and palladium-catalyzed coupling re

173 ered interest as replacements for alkene and alkyne hydrofunctionalization reactions.

174 AC to create a cyanide ligand along with the alkyne (i)Pr2N-C identical withC-N(i)Pr2.

175 The use of an alkyne in lieu of an alkene leads to the formation of is

176 termediate species is preferred for terminal alkynes, in contrast to the generally accepted migratory

177 itial gold-promoted adduct of the oxidant to alkyne, including its fragmentation into a highly reacti

178 kyne + Ti imido coupling, undergoes a second alkyne insertion followed by reductive elimination to yi

179 The controlled degradation of terminal alkynes into amides (by loss of one carbon) or ureas (by

180 metal catalysts convert terminal or internal alkynes into transient allylmetal species that display e

181 er mild conditions and low catalyst loading, alkynes, iodoperfluoroalkanes, (hetero)arylboronic acids

182 The metal-catalyzed coupling of alkynes is a powerful method for the preparation of 1,3-

183 The Glaser-Hay coupling of terminal alkynes is a useful synthetic reaction for the preparati

184 al intramolecular vicinal 1,2-diamination of alkynes is achieved for the synthesis of indole-cyclic u

185 A metal-free aminoarylation of internal alkynes is described, yielding tetrasubstituted enaminoa

186 etone-derived silyl enol ethers and terminal alkynes is described.

187 f groups of aryl(cyano)iodonium triflates to alkynes is described.

188 ective anti-hydrochlorination of unactivated alkynes is reported.

189 A wide range of terminal alkynes is tolerated under the reaction conditions, incl

190 biological samples by mass spectrometry and alkyne-labeled 1c can be employed for toxin derivatizati

191 Here, we used fatty acid-azide/alkyne labeling of mammalian cells, showing their transf

192 ing microscopy with integrated deuterium and alkyne labeling.

193 ment with base in the presence of alkenes or alkynes leads to alpha-methoxyenone-containing bicyclic

194 e hydroallylation of functionalized internal alkynes leads to the formation of skipped dienes contain

195 ier measurements on porphyrin oligomers with alkyne linkers exhibiting different preferred conformati

196 Alkyne metathesis and edge-specific postsynthetic modifi

197 in particular by solid-state NMR, and their alkyne metathesis catalytic activity is evaluated.

198 e give access to functionalized ring-opening alkyne metathesis polymerization (ROAMP) initiators [R-C

199 ating molybdenum species in the ring-opening alkyne metathesis polymerization (ROAMP) of ring-straine

200 that the initiation step of the ring-opening alkyne metathesis polymerization of 5,6,11,12-tetradehyd

201 roceed through dinitrogen extrusion, carbene/alkyne metathesis, and aromatic substitution to form fus

202 hen a triethylsilyl group is attached to the alkyne moiety and so generating alkenylsilanes that can

203 The alkyne moiety can be leveraged in downstream transformat

204 h covalently attaches the fluorophore to the alkyne moiety in the compounds.

205 pening following the initial reaction of the alkyne moiety.

206 possible by simply choosing the appropriate alkyne monomer.

207 to beta-sheets thereby placing the azide and alkyne motifs in proximity.

208 and (ii) an analogous series of dienophilic alkynes (n-C7H15COC identical withCR) for use in classic

209 ectroscopy revealed cis-hydrogenation of the alkyne occurs first.

210 mplementary reacting motifs, viz., azide and alkyne, of adjacent molecules in proximity.

211 eoxygenated derivatives with either terminal alkynes or borylated alkenes.

212 ntioselectivity, even in cases with internal alkynes possessing only very subtle steric differences b

213 BCl3 -induced borylative cyclization of aryl-alkynes possessing ortho-EMe (E=S, O) groups represents

214 e 2,3-disubstituted heteroarenes from simple alkyne precursors in one pot.

215 al and computational data now prove that the alkyne primarily acts as a four-electron donor ligand to

216 The reaction of terminal alkynes proceeded in poor yields while the use of bulkie

217 The internal alkyne products are obtained in yields of 41-95 % withou

218 Sulfur-terminated alkynes provide access to reactivity previously requirin

219 A study of the hydrocupration of internal alkynes provides new insight into the structure, stabili

220 was effective with a wide range of internal alkynes, providing products in a highly selective fashio

221 estrictions on homoallylic ring expansion in alkyne reactions and to develop a new general route for

222 , new tridecafullerenes-in which the central alkyne scaffold of [60]fullerene is connected to 12 suga

223 guing hydrogenation reactivity in catalyzing alkyne selectively to alkenes.

224 The enhanced alkyne signals result from the integration of alkyne gro

225 Lack of back-bonding facilitates alkyne slippage, which is energetically less costly for

226 ally, an inexpensive, commercially available alkyne source is employed in this formal homologation pr

227 riazine electron donor-acceptor dyad with an alkyne spacer has been investigated using a combination

228 s that are connected to a benzene bridge via alkyne spacers at para- and meta-positions.

229 ) (PPE) derivatives, are explored for use as alkyne-state-dependent Raman probes for living cell imag

230 or some target molecules, including terminal alkynes, strained rings, electronegative substituents, o

231 o-H dipyrrin featuring a conjugated terminal alkyne substituent was converted to its corresponding di

232 an additional alkene substituent but not an alkyne substituent.

233 Depending on the nature of the CAAC and alkyne substituents, these radicals can irreversibly dim

234 Treatment of the alkyne-substituted dipyrrin with BF3.OEt2 and NEt3 revea

235 up to 49%) in acidic C-H bonds of ketone and alkyne substrates (pKa from 18.7 to 28.8) was found at r

236 For alkyne substrates, the use of a catalyst incorporating t

237 An alkyne substructure in each candidate small molecule ena

238 Studies of six alkyne subtypes reveal that the rate-determining step (R

239 reviously requiring strong donor-substituted alkynes such as ynamides.

240 proceed through a concerted mechanism as in alkyne syn-hydroboration, or through an intramolecular 1

241 es as a surrogate for other well-established alkyne syntheses.

242 We have developed alkyne-tag Raman screening (ATRaS) for identifying bindi

243 reaction of pyrazoles and benzpyrazoles onto alkynes takes place chemoselectively without affecting t

244 coupling is not problematic in ARGET-ATRP of alkyne-terminated polymers because a reducing agent is p

245 The systematic variation of the alkyne, tethered-imine, or aryl iodide can allow the bui

246 alyzes the dearomatizing spirocyclization of alkyne-tethered aromatics far more effectively than the

247 A variety of alkyne-tethered indoles are suitable for this process.

248 SNO-OCTs are eight-membered heterocyclic alkynes that have fast rates of reactivity with 1,3-dipo

249 o isomers involved symmetrical disubstituted alkynes that were reduced to Z-olefins followed by borep

250 e the myriad of Au(I)-catalyzed reactions of alkynes, the mono Au(I)-catalyzed pendant to the radical

251 tes beyond 1,3-dienes to include olefins and alkynes; this provides a new synthetic route to valuable

252 clobutene intermediate, resulting from [2+2] alkyne + Ti imido coupling, undergoes a second alkyne in

253 R data reveal the occurrence of an efficient alkyne to allene isomerization of the spacer with a time

254 ioselective chloropalladation of an internal alkyne to generate a nucleophilic vinyl Pd(II) species,

255 eloped for [6 + 2] cycloaddition of terminal alkynes to 1,3,5,7-cyclooctatetraene to give substituted

256 hanism for the initial reaction of HONO with alkynes to form acyloximes (e.g., 13c) has been explored

257 nd regioselective hydrocyanation of terminal alkynes to furnish E-configured alkenyl nitriles.

258 is also compatible with allenes in place of alkynes to furnish tetrasubstituted alkenyl halides, sho

259 atalyst-free formal thioboration reaction of alkynes to gain mechanistic insight into B-chlorocatecho

260 Copper-mediated coupling between alkynes to generate a structurally rigid, linear 1,3-diy

261 oupling between alpha-branched aldehydes and alkynes to generate vicinal quaternary and tertiary carb

262 hat undergo cycloaddition with unsymmetrical alkynes to give indolizidines with good regio- and stere

263 ediate formed in situ by hydroamination of 1-alkynes to give the corresponding propargylamine derivat

264 The addition of terminal alkynes to racemic beta-stereogenic alpha-keto esters wa

265 ,3-dioxolanes and dioxanes by trimethylsilyl alkynes to set diol-derived propargyl trimethylsilyl bis

266 ed the reactivity of the conjugated terminal alkyne toward Lewis-activated electrophilic substitution

267 In a number of cases alkyne trans-haloboration occurs alongside, or instead o

268 ng from benzaldehydes, 2-aminothiazoles, and alkynes under copper(I,II) catalysis was developed.

269 ety of substituted arylglyoxals and internal alkynes undergo the transformation in the presence of Fe

270 the mono Au(I)-catalyzed dimerization of two alkyne units as well as the transannular ring closure re

271 to the radical dimerization of nonconjugated alkyne units has not been investigated by quantum chemic

272 ligonucleotides that contain 5'-azide and 3'-alkyne units.

273 es onto functionalized terminal and internal alkynes using a super basic solution of KOH/DMSO has bee

274 n ketone beta-C(sp(3))-H bonds and aliphatic alkynes using an in situ-installed directing group.

275 An aluminum-catalyzed hydroboration of alkynes using either the commercially available aluminum

276 lation (formal hydrotrifluoromethylation) of alkynes using the fluoroform-derived [CuCF3] reagent is

277 Alkynes usually oligomerize to give rings with a conjuga

278 The impact of different substrates (alkynes versus allenes) on the reaction mechanism has be

279 ging due to synergetic enhancement effect of alkyne vibrations in Raman-silent region compared to alk

280 lding a propargylic diazene that performs an alkyne walk to afford the allene.

281 hydrogenative coupling (CDC) with a terminal alkyne was developed.

282 t oxidative coupling of phenols and terminal alkynes was achieved at room temperature by a visible-li

283 heterocycloaddition of a urea-functionalized alkyne, well-defined precatalyst 3 provides high regiose

284 ariety of functionality including azides and alkynes were installed on tri-N-acetylglucosamine (NAG)3

285 ng group) cascade transformations of skipped alkynes where the reactivity of the key radical precurso

286 ble C-H activation by employing an excess of alkyne, where both annulation and hydroarylation took pl

287 nt of a hydride addition to a gold-activated alkyne with subsequent C-B bond formation.

288 hanism for the gold(I)-catalyzed reaction of alkynes with alkenes is proposed on the basis of density

289 es of the sigma-bond metathesis of silylated alkynes with aromatic carboxylic acids on the Ag(111) an

290 onogashira Pd-catalyzed coupling of terminal alkynes with aryl iodides.

291 rbocycles from the reaction of disubstituted alkynes with beta- or gamma-dicarbonyl systems.

292 ed method for the 1,1-diboration of terminal alkynes with bis(pinacolato)diboron (B2Pin2) is describe

293 e E-selective products from a broad group of alkynes with good yields and E/Z selectivity.

294 catalyze the cis-selective hydrogenation of alkynes with higher rates, conversions, and selectivitie

295 A catalytic hydroamidation of alkynes with isocyanates using alkyl bromides as hydride

296 e hydroallylation of terminal alkyl and aryl alkynes with simple allyl phosphates and 2-substituted a

297 ntermolecular aminosulfonylation of terminal alkynes with sodium sulfinates and TMSN3 is reported.

298 The selective annulation reaction of alkynes with substrates containing inert C-H bonds using

299 hydrocarbonylative C-C coupling of terminal alkynes with unactivated alkyl iodides has been develope

300 A direct hydroalkylation of disubstituted alkynes with unfunctionalized ethers and amides was achi