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1                                                             All analyses were adjusted for age, sex, and education.
2                                                             All analyses were adjusted for demographics and standard COPD
3                                                             All analyses were adjusted for gestational age, sex, birth we
4 ndard deviation over 4 postbaseline LDL-C measurements, and all analyses were adjusted for mean LDL-C levels and cardiova
5                                                             All analyses were also stratified by the apolipoprotein E phe
6                                                             All analyses were based on individual participant data.
7                                                             All analyses were based on the intention-to-treat principle a
8                                                             All analyses were by intention to treat.
9                                                             All analyses were conducted by determining the 95% Bayesian c
10                                                             All analyses were conducted by using Cox proportional hazards
11                                                             All analyses were conducted in an intention-to-treat populati
12                                                             All analyses were conducted using weighted data.
13                                                             All analyses were corrected for TSPO rs6971 polymorphism (whi
14                                                             All analyses were covaried for age and body mass index.
15                                                             All analyses were descriptive.
16                                                             All analyses were done at individual country level and groupe
17                                                             All analyses were done at the country level and then aggregat
18                                                             All analyses were done by intent to treat.
19                         The primary endpoint was safety and all analyses were done by intention to treat.
20                                                             All analyses were done by modified intention to treat.
21 s (part A) and safety (part B) of lumacaftor and ivacaftor; all analyses were done in children who received at least one
22                                                             All analyses were done in populations aged 30-79 years due to
23                                                             All analyses were done in the intention-to-treat population;
24     The primary endpoint was progression-free survival, and all analyses were done on intention-to-treat basis among elig
25                                                             All analyses were done on the intention-to-treat population a
26                                                             All analyses were done using an intention-to-treat approach.
27                                                             All analyses were done using the modified intention-to-treat
28                                                             All analyses were done with the modified intention-to-treat p
29                                                             All analyses were intention to treat with the exception of sa
30                                                             All analyses were intention to treat.
31                                                             All analyses were intention-to-treat.
32                                                             All analyses were per protocol.
33                                                             All analyses were performed in 2-year blocks, where each indi
34                                                             All analyses were performed in the overall population and acc
35                                                             All analyses were performed separately in each ancestry group
36                                                             All analyses were performed using Comprehensive Meta-Analysis
37                                                             All analyses were performed using left eye data.
38                                                             All analyses were performed using SAS software.
39                                                             All analyses were performed with the use of proportional-haza
40                                                             All analyses were prespecified in the protocol and the statis
41                                                             All analyses were prespecified in the study protocol.
42                                                             All analyses were repeated for incident coronary heart diseas
43                                                             All analyses were run across all participants and repeated re
44                                                             All analyses were stratified by race/ethnicity in the main an
45                                                             All analyses were stratified by sex and additionally by race.
46                                                             All analyses were stratified by sex.
47                                                             All analyses were stratified by timing of birth.
48                                                             All analyses were two sided, and P values less than .10 were
49                                                             All analyses were weighted for sampling and design effects.
50                                                             All analyses were weighted to account for the complex survey