ライフサイエンスコーパス: all-or-none

1 ain why subjective experience of VSTM is not all or none.

2 FCCP, showed a response that was essentially all-or-none.

3 ne and sorbitol were found to be essentially all-or-none.

4 e type of dye release changed from graded to all-or-none according to prediction.

5 rendering codes that are based on classical, all-or-none action potentials unworkable.

6 g information only by the timing and rate of all-or-none action potentials.

7 ed-pulse depression, large initial EPSPs, an all-or-none activation profile, and no metabotropic rece

8 and NFAT-dependent gene expression display "all-or-none" activation that is exclusively driven by lo

9 nule cell layer in cerebellar slices elicits all or none alpha-amino-3-hydroxy-5-methyl-4-isoxazolepr

10 ion and to climbing fiber input with a large all-or-none AMPA-mediated EPSP that shows paired pulse d

11 The all-or-none and composite care summary measures were als

12 udoknots, natural resistance was essentially all-or-none and correlated with the identity of the amin

13 Unitary plasticity events were all-or-none and drove synaptic strength between extremes

14 ties, where graded inputs are converted into all-or-none and hybrid responses.

15 lenge the view that these calcium spikes are all-or-none and only signal whether the instructive stim

16 n are characterized better as graded than as all-or-none and that priming need not arise from a mecha

17 ganized and capable of gradual, oscillatory, all-or-none, and subpopulation-generating responses.

18 ded in the axon at distances > 25 microm are all-or-none, and uniform in amplitude even when action p

19 That an all-or-none apparent sex difference in neuronal types is

20 heir large size, paired-pulse depression and all-or-none appearance in response to a graded stimulus.

21 mossy fibre inputs were identified by their all-or-none appearance in response to a graded stimulus.

22 herence to individual discharge measures and all-or-none appropriate care measures for acute myocardi

23 scle, C. elegans body-wall myocytes generate all-or-none APs, which evoke Ca2+ release from the sarco

24 alyzed DNA unwinding is often studied using "all or none" assays that detect only the final product o

25 , when coupled, the population was recruited all-or-none at threshold into a rhythmic swimming patter

26 such as NtrC1 or PspF, a novel cis-mediated "all or none" ATP binding occurs in the heptameric FlrC(C

27 This all-or-none behavior suggests a mechanism by which chrom

28 transporter and reporter plasmids, exhibited all-or-none behavior.

29 ees C or greater, which was indicative of an all-or-none behavior.

30 nse to the inducer galactose as well as the "all-or-none" behavior characteristic of many eukaryotic

31 ic response reveals ultrasensitivity and an "all-or-none" behavior, hallmarks of a bistable switch me

32 emonstrating that both can show regenerative all-or-none behaviour.

33 At a fixed site, the response is close to 'all-or-none' behaviour which suggests that calcium spark

34 ation-inducing hormone progesterone, into an all-or-none biological response-oocyte maturation.

35 cing of Sxl primary transcripts generates an all-or-none bistable behavior and constitutes an efficie

36 ochasticity results in the observation of an all-or-none bistable response over a much wider range of

37 lts and that regulatory factors may not make all-or-none, black-or-white contributions to infectivity

38 f both elt-7 and elt-2 results in a striking all-or-none block to morphological differentiation of gr

39 nversions of signaling gradients into sharp "all-or-none" borders are fundamental to tissue and organ

40 xamined the ionic conductances that underlie all-or-none burst firing elicited in acutely dissociated

41 Cerebellar Purkinje neurons often generate all-or-none burst firing in response to depolarizing sti

42 in the superior colliculus gives rise to an all-or-none burst response that signals threshold crossi

43 continuous pool, but rather, it is due to an all-or-none Ca(2+) release from a compartmentalized Ca(2

44 e been proposed to resolve this paradox: (i) all-or-none Ca(2+) release from heterogeneous stores tha

45 lace the in vivo resting MET current, evoked all-or-none calcium spikes (39-75 mV amplitude) in 37% o

46 ar cells are all capable of generating fast 'all-or-none' calcium transients modulated by visual stim

47 als with EHRs had similar odds of receiving "all-or-none" care (odds ratio [OR]: 1.03; 95% CI: 0.99 t

48 ients of extracellular signals into discrete all-or-none cellular responses, such as mitogenesis and

49 he acid side of the profile, compared to the all or none change observed for wt giving a p K a of abo

50 y distinct cellular identities by triggering all-or-none changes in expression of combinations of tra

51 Here evidence is presented that the all-or-none character of the response is generated by th

52 ings provide a biochemical rationale for the all-or-none character of this cell fate switch.

53 The all-or-none character of transmission at central synapse

54 This assumption leads frequently to an "all or none" choice of either preserving coastal habitat

55 tipolar Purkinje cells showed characteristic all-or-none climbing fiber responses.

56 ormance, adherence measured through a global all-or-none composite infection-prevention score was ass

57 ures (S-INF) were aggregated into 2 separate all-or-none composite scores.

58 (constitutively active CREB) would break the all-or-none concordance.

59 of bacterial genes are found to exhibit an 'all-or-none' control mechanism that adapts the bacterium

60 tion of hERG1 channels involves a concerted, all-or-none cooperative interaction between all four sub

61 the oxidative stress stimulus, leading to an all-or-none cytoprotective or pro-apoptotic signaling re

62 a model explaining this complex, stochastic all-or-none dataset.

63 ltiple internal and external signals into an all-or-none decision to enter the cell cycle.

64 ed on genomic biomarkers generally entail an all-or-none decision, which may be misleading for clinic

65 bicans to 'test the waters' before making an all-or-none decision.

66 uggest that target predictions must consider all or none decisions by individual seed nucleotides.

67 review preclude their widespread use to make all-or-none decisions about whether to screen individual

68 n of 1 pA of current triggered a maintained 'all-or-none' depolarization to a plateau of -34 mV, asso

69 timing of the shock, demonstrating a classic all-or-none depolarizing response.

70 muscle-type proprioceptor character, we find all-or-none differences in gene expression for proprioce

71 s at which graded signals are converted into all-or-none distinctions in cell identity remain poorly

72 As such, this is an "all-or-none" DNA unwinding assay.

73 ed indicated that the beta-subunit exerts an all-or-none effect on the Ca2+ sensitivity and kinetics

74 raded release in general, which, contrary to all-or-none efflux, has not been well-understood.

75 tal-like output, we envisage that the use of all-or-none enzymatic responses will also improve our ab

76 T input and 30% with IX input responded with all-or-none EPSCs.

77 ontaining m bp, each of which experiences an all-or-none equilibrium between a straight and a uniform

78 e show that regenerative CICR develops as an all-or-none event in cultured rat dorsal root ganglion n

79 ve examined whether channel maturation is an all-or-none event or whether heterogeneous processing of

80 s within an individual channel complex is an all-or-none event such that channels present on the cell

81 lar signaling by antigen receptors is not an all-or-none event, and these external variables alter bo

82 like the peristaltic reflex, the CMMC is an 'all or none' event that appears to be dependent upon Dog

83 ld view that the climbing-fibre input is an 'all-or-none' event.

84 he initiation of bidirectional plasticity by all-or-none events may help confer robustness on memory

85 ods, spike metrics operate on time series of all-or-none events, and are, thus, particularly appropri

86 tors, silencing and reactivation occurred in all-or-none events, enabling the regulators to modulate

87 All-or-none failures of multiquantal IPSC components als

88 nd GF, with both cell types responding in an all or none fashion when measured at day 2, and in a con

89 nzyme rapidly, stoichiometrically, and in an all or none fashion, rather than variably over a large r

90 of contents from lipid vesicles occurs in an all-or-none fashion and the differences between PC/PG 50

91 all proteins fold highly cooperatively in an all-or-none fashion and thus their native states are wel

92 analysis showed that ERK is activated in an all-or-none fashion in both wild-type and KSR1-deficient

93 lti-switch", directing differentiation in an all-or-none fashion to a specific cell-type chosen among

94 diversion to a myeloid-like phenotype, in an all-or-none fashion with multiple, coordinate gene expre

95 the kinesin-based microtubule movement in an all-or-none fashion without lowering kinesin ATPase acti

96 translocation into the nucleus occurs in an all-or-none fashion, dependent on complete dephosphoryla

97 f one neuron in a network could evoke, in an all-or-none fashion, reverberatory activity lasting for

98 tranded form that was saturated by g5p in an all-or-none fashion.

99 nd S2 in the absence of force proceeds in an all-or-none fashion.

100 s consecutive unfolding of each domain in an all-or-none fashion.

101 ted by the dosage compensation pathway in an all-or-none fashion.

102 nchback (hb) gene in the anterior half in an all-or-none fashion.

103 als are thought to release transmitter in an all-or-none fashion; either one synaptic vesicle undergo

104 ng alleles in which exon 3 is spliced in an "all-or-none" fashion.

105 hexameric HerA binds six nucleotides in an 'all-or-none' fashion, HerA-NurA harbors a highly coordin

106 iring, and brief depolarization then induced all-or-none firing of conglomerate action potentials com

107 Graded and all-or-none fluxes correspond to unimodal and bimodal di

108 ts, but the leakage mechanism was different (all-or-none for PI and graded release for PIP vesicles).

109 gamma1:alpha-subunits, the results reveal an all-or-none functional regulation of BK channels by gamm

110 f function (efficiency alleles), rather than all-or-none, gain-of-function, or loss-of-function allel

111 This all-or-none, global electrical and biochemical signaling

112 triggering (a probabilistic process that is all-or-none in a single simulation).

113 surface activation marker, were essentially all-or-none in character.

114 nses of cooperative enzymes; or bistable and all-or-none in character.

115 1 and help make the process irreversible and all-or-none in character.

116 nose-inducible promoter P(BAD) is subject to all-or-none induction, in which intermediate concentrati

117 ller than that of dye flux through the pore, all-or-none influx occurs.

118 well suited to being a Ca2+ sensor for rapid all-or-none intercellular membrane-related events.

119 on of afferents from area X evoked a strong, all-or-none IPSP whose amplitude and latency were unchan

120 But overall, magainin follows the same all-or-none kinetic model as cecropin A in these lipid m

121 The all-or-none kinetic model that we recently proposed for

122 tiated synapses, and (4) both LTP and HD are all-or-none, leading de facto to binary-valued synaptic

123 enon of contents release, together with some all-or-none leakage (at low ceramide concentrations or s

124 These species are stable, result in all-or-none leakage, and represent a definable protein/l

125 channels in the bilayer should cause only an all-or-none leakage.

126 erefore, melting behavior of the hairpins is all-or-none like.

127 two RP states are exchangeable mainly due to all-or-none-like conductance changes of the inward-recti

128 d that transmission of frequency signals is "all-or-none", limited by a critical frequency (f(c)).

129 All-or-none LOI could lead to a second distinct cell pop

130 d to cdG, they work together with RcdA in an all-or-none manner to reduce the Km of CtrA proteolysis

131 found that ICRAC activates in an essentially all-or-none manner when the current is evoked by recepto

132 ction potentials propagate along axons in an all-or-none manner, subthreshold membrane potential fluc

133 ike phenotype only previously observed in an all-or-none manner.

134 ted chloride currents that were evoked in an all-or-none manner.

135 ors in single spines depressed rapidly in an all-or-none manner.

136 andles show that they unfold in a reversible all-or-none manner.

137 individual chromosomal copies of TMS1 in an all-or-none manner.

138 physiological and pathological stimuli in an all-or-none manner.

139 able steady state directly to another, in an all-or-none manner.

140 the anterior half of the embryo in a nearly all-or-none manner.

141 The popular "all-or-none" measurement approach was also dominated by

142 Instead of an all-or-none mechanism of allostery, these findings suppo

143 optotic Bax forms large, stable pores via an all-or-none mechanism that can release cytochrome c.

144 e contents are released, consistent with the all-or-none mechanism.

145 c model is implemented for a peptide with an all-or-none mechanism.

146 ated, was relatively constant, suggesting an all-or-none mechanism.

147 ite QI was calculated through the use of the all-or-none method.

148 slope of 1.0, a tell-tale characteristic of all-or-none mnemonic representations.

149 We present a simple two-state, all-or-none model for bimolecular hybridization of non-s

150 econdary structure profiles as multivariant, all-or-none models, which subsume covariant models.

151 In contrast, the all-or-none motor patterns underlying wing expansion are

152 ic potentials (EPSPs) of regular (n =76) and all-or-none (n =24) type in layer 2/3 pyramidal cells in

153 Chemosensitivity is not an all-or-none neuronal property, and the degree of chemose

154 t these oscillators operate best with either all or none of their intersegmental inputs.

155 se results reveal a complex response, not an all-or-none one, which results in multiple effector phen

156 rons responded to ST stimulation with either all-or-none or graded amplitude EPSCs.

157 hreshold depolarizations that occurred in an all-or-none or graded manner, due to recruitment of T-ty

158 compliance accounting for total compliance (all or none) or for partial compliance ("dose" or number

159 trength of individual synapses in a digital (all-or-none) or analog (graded) manner.

160 Thus, MBNL1 loss does not have an all or none outcome but rather shows a graded effect on

161 tems to convert graded inputs into decisive, all-or-none outputs.

162 onverting graded input signals into discrete all-or-none outputs.

163 function of postsynaptic receptors, and are all-or-none overshooting events, rather than graded pote

164 Here we show that there is a striking all or none pattern for CTL escape mutations in HIV-1 Ga

165 karyotic cellular mRNAs generally follow an 'all-or-none' pattern.

166 ar function, beyond eliciting the well known all-or-none PC complex spike.

167 t may be achieved by mixing a graded with an all-or-none permeabilizer.

168 on, and suggest they should be viewed not as all-or-none phenomena, but as a continuing series of bio

169 and joining (J) recombination is not just an all or none phenomenon.

170 The simulation results show that the all-or-none phenomenon is governed largely by random cel

171 formation of each hypersensitive site was an all-or-none phenomenon.

172 iod of hours, the release of proteins is an "all or none" phenomenon that is completed in an individu

173 lar processes, was developed to examine the "all-or-none" phenomenon observed in autocatalytic system

174 Therefore peristalsis is not necessarily an "all-or-none" phenomenon.

175 coefficient of 12 and resembles an apparent 'all-or-none' phenomenon.

176 laboratory observations, including certain 'all-or-none' phenotypes and complex differentiation patt

177 the ulnar nerve at the elbow, and recording all-or-none potentials from flexor carpi ulnaris.

178 Individual synapses appear to have all-or-none potentiation indicative of highly cooperativ

179 lly translates only strong Ca2+ signals into all-or-none potentiation of individual hippocampal synap

180 maternally imprinted gene, occurs through an all-or-none process leading to a mixture of fully imprin

181 tive-feedback loop, which contributes to the all-or-none process of oocyte maturation.

182 tes that the inactivation of POD by PL is an all-or-none process related to loss of helical structure

183 of small proteins has been assumed to be an all-or-none process that involves high cooperativity wit

184 protein structures are assumed to fold in an all-or-none process that is inaccessible to experiment.

185 nt with our hypothesis that LOI occurs by an all-or-none process.

186 data for Naf-BBL remain consistent with the all-or-none process.

187 ) plane shows that the hairpin unfolds by an all-or-none process.

188 -induced leakage of liposome contents was an all-or-none process.

189 ition from prepore to pore appears to be an "all or none" process; partial insertion of the transmemb

190 The all-or-none properties of spike generation and active me

191 es occur randomly in space and time, exhibit all-or-none properties, and provide a vital source of su

192 hemosensitivity has often been considered an all-or-none property.

193 This all-or-none reaction may serve as a switch that determin

194 rization and action selection, leading to an all-or-none reconfiguration of sensory-motor mapping.

195 y, the adaptation of glutamate terminals was all-or-none; recycling vesicle pool size at remaining ac

196 nput and under certain conditions even evoke all-or-none regenerative potentials.

197 quency of quantal events, consistent with an all-or-none regulation (up or down) of clusters of alpha

198 partial release from a continuous pool or an all-or-none release from a compartmentalized pool.

199 The mechanism of the all-or-none release of the contents of phospholipid vesi

200 hatidylglycerol (POPG) bilayers that lead to all-or-none release of vesicle contents.

201 adine, verapamil, and pinacidil each induced all-or-none repolarization at some epicardial sites but

202 tified nonlinear signaling that organizes an all or none response during particle ingestion.

203 ed with IgG density, later signals showed an all or none response, which was regulated by the concent

204 the inferior olive, which evokes a powerful all-or-none response denoted as the complex spike.

205 feedback loop whose potential to generate an all-or-none response in single cells has been a paradigm

206 l evidence points to a graded rather than an all-or-none response in the natural lactose uptake syste

207 ranulation remained unchanged, suggesting an all-or-none response of mast cells after FcepsilonRI tri

208 f a metabotropic glutamate component, and an all-or-none response pattern, which are all signatures o

209 size, a mechanism to read the signal, and an all-or-none response triggered only when the signal reac

210 Lung edema forms (possibly as an all-or-none response) depending not only on global strai

211 This process appears also to follow an all-or-none response, as the vast majority of the crown

212 sensitivity, the phenomenon equivalent to an all-or-none response, in dissociated neural precursor ce

213 sifications imply that treatment leads to an all-or-none response, with potentially important clinica

214 n cell cultures, ERK1/2 activation is not an all-or-none response.

215 nregulated enzymes into a sharp, effectively all-or-none response.

216 gated several alternative mechanisms for the all-or-none response: (1) the univesicular release const

217 for OspC production, spirochetes display an "all or none" response, with some cells displaying high l

218 results suggest that, rather than triggering all or none responses, EGFR coordinates partially indepe

219 Here we show that all-or-none responses can be generated at a transcriptio

220 apical dendrites generated cadmium-sensitive all-or-none responses that were subthreshold for somatic

221 scade in Xenopus oocytes exhibits sustained, all-or-none responses to graded, transient stimuli.

222 Calcium transients produced by all-or-none responses were not restricted to the sites o

223 A responses included synaptic depression and all-or-none responses, while Class 1B responses exhibite

224 titration") can generate ultrasensitive or "all-or-none" responses that are equivalent to highly coo

225 cetylglucosamine, N-acetylneuraminic acid), 'all-or-none' responses (d-xylose, l-rhamnose) and comple

226 However, at higher field strengths this all-or-none sensitivity reverts to a more gradual transi

227 the view that the climbing fiber conveys an all-or-none signal to the cerebellar cortex and help to

228 synapses where the presynaptic signal is an all-or-none spike, the probabilistic manner of neurotran

229 extended activation domain to guarantee the 'all or none' splicing switch that is required during Dro

230 An all-or-none step led to final release of ESCRT-III and V

231 The distribution of isoforms was mostly all or none, suggesting on/off switching as a frequent m

232 ity and changed its leakage mechanism toward all-or-none, suggesting more specific, larger, and/or lo

233 Simulations further indicated an all-or-none switch to HA-mac at threshold levels of HbHp

234 that, in addition to the generally observed all-or-none switch, the basal transcription machinery al

235 Furthermore at some all-or-none synapses, changes of averaged response ampli

236 ected if the protein is a truly cooperative, all-or-none system.

237 Rather than being all-or-none, telomere deprotection would thus proceed fi

238 er to a triple helix is best described by an all-or-none third-order reaction.

239 tion gradients of extracellular factors into all-or-none threshold responses leading to discrete patt

240 to be maintained, changed dramatically from all-or-none to graded in the mutants of cecropin and mag

241 operate in different functional regimes: the all-or-none toggle or the linear filter mode, depending

242 All-or-none total bundle compliance increased from 4.9-7

243 le-negative feedback loop, ensuring a robust all-or-none transition for Clb5/6-Cdk1 activity.

244 H are in excellent agreement, indicating an all-or-none transition for this triplex.

245 ard- and inward-facing forms, rather than an all-or-none transition of the three subunits, a mechanis

246 ions of a chemical denaturant, preceding the all-or-none transition to the unfolded state.

247 end, the folding and unfolding appears as an all-or-none transition.

248 though global folding can be described as an all-or-none transition.

249 on of the knob-hole interactions was not an "all-or-none" transition as it occurred through distinct

250 Here we characterize step-like all-or-none transitions from baseline synaptic transmiss

251 ows both the N- and C-domain to fold through all-or-none transitions with similar refolding rates.

252 on response region RNA hairpin unfolds in an all-or-none two-state reaction at any loading rate with

253 To date, human studies have demonstrated an "all-or-none" type of control for a fixed number of pre-d

254 and L19P) resulted in sawtooth patterns with all-or-none unfolding events that elongated the molecule

255 beta-strand, produced sawtooth patterns with all-or-none unfolding events that lengthened the molecul

256 tely reproduced by the simple kinetics of an all-or-none unfolding process.

257 e response test, phase shifts appeared to be all-or-none with threshold irradiance between 140 and 10