ライフサイエンスコーパス: all-trans-retinoic acid

1 and is rapidly down-regulated in response to all-trans retinoic acid.

2 eatment of acute promyelocytic leukemia with all-trans retinoic acid.

3 and was rescued by treatment with exogenous all-trans retinoic acid.

4 hat is further enhanced by co-treatment with all-trans retinoic acid.

5 tly, this is counteracted in the presence of all-trans retinoic acid.

6 noid metabolism by HSCs and was dependent on all-trans retinoic acid.

7 The top hit identified in the screen was all-trans-retinoic acid.

8 these tumors may be amenable to therapy with all-trans-retinoic acid.

9 ced their differentiation in the presence of all-trans-retinoic acid.

10 ehyde, the immediate precursor for bioactive all-trans-retinoic acid.

11 The addition of all-trans retinoic acid, a commonly used agent for the t

12 Accordingly, all-trans-retinoic acid, alone or together with gemfibro

13 Treatment of APL blasts with all-trans retinoic acid also did not result in immediate

14 s important therapeutic agents; for example, all-trans retinoic acid, an activating ligand for retino

15 Patients had significantly lower levels of all-trans retinoic acid and 13-cis retinoic acid than co

16 l-trans retinol), and its geometric isomers, all-trans retinoic acid and 9-cis retinoic acid, in a fo

17 Upon treating APL with all-trans retinoic acid and achieving complete remission

18 patients with t(15;17) treated with extended all-trans retinoic acid and anthracycline-based chemothe

19 patients with APL homogeneously treated with all-trans retinoic acid and anthracycline-based chemothe

20 emains high despite the wide availability of all-trans retinoic acid and appears significantly higher

21 Thanks to modern treatment with all-trans retinoic acid and chemotherapy, acute promyelo

22 APL cells from these mice were responsive to all-trans retinoic acid and had virtually no differences

23 All patients received All-trans retinoic acid and idarubicin according to the

24 We hypothesize that topical all-trans retinoic acid and interferon alfa-2b may act s

25 er rates of apoptosis in FBAE cells than did all-trans retinoic acid and the control (P = 0.004).

26 th acute promyelocytic leukemia treated with all-trans retinoic acid and/or arsenic trioxide.

27 myelocytic leukemia (APL) who were receiving all-trans-retinoic acid and anthracycline-based chemothe

28 pregulated during differentiation induced by all-trans-retinoic acid and brain-derived neurotrophic f

29 d also increased Bcl2a1 expression, although all-trans-retinoic acid and ligands for other RXR partne

30 for rapid stimulation of dendritic growth by all-trans-retinoic acid and reveal that the ligand-depen

31 with other targeted therapies such as ATRA (all trans retinoic acid) and arsenic trioxide.

32 Novel mutual prodrugs (MPs) of ATRA (all- trans-retinoic acid) and HDIs (histone deacetylase

33 Finally, vitamin A (all-trans retinoic acid) and vitamin D (1,25-dihydroxyvi

34 Furthermore, ketoconazole, all-trans retinoic acid, and cyclosporine inhibited CYP3

35 Retinoids (i.e., vitamin A, all-trans retinoic acid, and related signaling molecules

36 1) concentration-dependent, 2) selective for all-trans-retinoic acid, and 3) requires the presence of

37 L-nuclear bodies, enhanced responsiveness to all-trans-retinoic acid, and induced cellular differenti

38 Treatment with all-trans retinoic acid antagonizes stress-induced activ

39 rging data indicates that retinoids, such as all trans retinoic acid (ATRA) and its precursor all tra

40 can be dissociated by pharmacologic doses of all trans retinoic acid (ATRA) inducing differentiation

41 All trans retinoic acid (atRA) is one of the most potent

42 c conditions, TNIP1 expression is induced by all trans retinoic acid (ATRA).

43 dies, a phenotype reversed by treatment with all trans retinoic acid (ATRA).

44 ion with fibrillar fibronectin and show that all trans-retinoic acid (ATRA), which induces PSC quiesc

45 APL0406 trial showed that the combination of all- trans-retinoic acid (ATRA) and arsenic trioxide (AT

46 In nude mice models, combination of all-trans retinoic acid (ATRA) and AEG-1 knockdown syner

47 We examined whether combining all-trans retinoic acid (ATRA) and arsenic trioxide (ATO

48 nockdown of NPM1 also sensitized OCI-AML3 to all-trans retinoic acid (ATRA) and cytarabine.

49 We used all-trans retinoic acid (ATRA) and histone deacetylase (

50 we have identified a novel pathway involving all-trans retinoic acid (ATRA) and its receptor (RARgamm

51 Here we show that all-trans retinoic acid (ATRA) and other agonists of the

52 treatment until the recent identification of all-trans retinoic acid (ATRA) as a Pin1 inhibitor.

53 The identification of all-trans retinoic acid (ATRA) as a potent Pin1 inhibito

54 g from 5 large clinical trials that included all-trans retinoic acid (ATRA) as part of induction, we

55 We show that treatment with all-trans retinoic acid (ATRA) at clinically achievable

56 ng hematologist because early institution of all-trans retinoic acid (ATRA) at the first suspicion of

57 reatment of PML-RARalpha leukemic cells with all-trans retinoic acid (ATRA) causes them to differenti

58 neuroblastoma cells following treatment with all-trans retinoic acid (ATRA) compared to controls.

59 Because all-trans retinoic acid (ATRA) decreases inflammation in

60 All patients received all-trans retinoic acid (ATRA) during induction, each co

61 The treatment of patients with all-trans retinoic acid (ATRA) effectively ameliorates t

62 , we demonstrated that treatment of AML with all-trans retinoic acid (ATRA) enhanced FRbeta expressio

63 that differentiate along this lineage after all-trans retinoic acid (ATRA) exposure.

64 x 10(9)/L (or for a maximum of 28 days) and all-trans retinoic acid (ATRA) for 90 days.

65 Recent studies have shown that all-trans retinoic acid (ATRA) had a potent activity in

66 All-trans retinoic acid (ATRA) has been used in several

67 eatment of acute promyelocytic patients with all-trans retinoic acid (ATRA) has improved the survival

68 of cancer stem cells through treatment with all-trans retinoic acid (ATRA) have yielded limited succ

69 mpounds to enhance the biological effects of all-trans retinoic acid (ATRA) in a retinoid-responsive

70 ibition relieved by pharmacological doses of all-trans retinoic acid (atRA) in culture and in vivo.

71 Treatment with all-trans retinoic acid (ATRA) increased both the expres

72 All-trans retinoic acid (ATRA) increased IRF4 expression

73 The vitamin A metabolite all-trans retinoic acid (ATRA) induces a gut-homing phen

74 All-trans retinoic acid (ATRA) induces clinical remissio

75 All-trans retinoic acid (ATRA) induces differentiation i

76 All-trans retinoic acid (ATRA) induces differentiation o

77 udy provides the first evidence showing that all-trans retinoic acid (ATRA) induces the interaction a

78 We determined the mechanism by which all-trans retinoic acid (ATRA) inhibits experimental aut

79 All-trans retinoic acid (ATRA) neutralizes the different

80 -cis RA, 9-cis retinoic acid (9-cis RA), and all-trans retinoic acid (ATRA) on cell proliferation, ap

81 herefore, we examined the effect of TCDD and all-trans retinoic acid (atRA) on the expression of matr

82 H/+; Pdx-1-Cre (KPC) mice and the effects of all-trans retinoic acid (ATRA) on these processes.

83 Comparison of monocytes stimulated with all-trans retinoic acid (ATRA) or 1,25-dihydroxyvitamin

84 t PLZF/RAR alpha leukemia, was responsive to all-trans retinoic acid (ATRA) or As2O3 treatments.

85 ute promyelocytic leukemia by treatment with all-trans retinoic acid (ATRA) plus arsenic trioxide (AT

86 This study found that all-trans retinoic acid (atRA) reverses the effects of H

87 All-trans retinoic acid (atRA) reverses the HIV-induced

88 Treatment of monocytes with all-trans retinoic acid (ATRA) significantly decreased b

89 We investigated the benefit of adding all-trans retinoic acid (ATRA) to chemotherapy for young

90 We used all-trans retinoic acid (ATRA) to differentiate MDSCs in

91 Dendritic cells (DCs) use all-trans retinoic acid (ATRA) to promote characteristic

92 ay initiated from the nongenomic activity of all-trans retinoic acid (atRA) to stimulate complex form

93 While all-trans retinoic acid (ATRA) treatment in acute promye

94 Interestingly, all-trans retinoic acid (ATRA) treatment induced potent

95 In acute promyelocytic leukemia (APL), all-trans retinoic acid (ATRA) treatment induces granulo

96 All-trans retinoic acid (ATRA) upregulated TRAIL-R1 expr

97 All-trans retinoic acid (ATRA) was negatively connected

98 The effects of all-trans retinoic acid (ATRA) were studied in LSL-KrasG

99 rly vulnerable to a novel strategy combining all-trans retinoic acid (ATRA) with arsenic trioxide (AT

100 All-trans retinoic acid (ATRA) with chemotherapy is the

101 All-trans retinoic acid (ATRA), a derivative of vitamin

102 All-trans retinoic acid (ATRA), a natural retinoid, arre

103 All-trans retinoic acid (ATRA), a potent derivative of v

104 dy was to evaluate the therapeutic effect of all-trans retinoic acid (ATRA), an active metabolite of

105 d with daunorubicin, cytarabine (Ara-C), and all-trans retinoic acid (ATRA), and complete remission w

106 ) in response to its natural agonist ligand, all-trans retinoic acid (atRA), and is repressed by SHP.

107 onducted to examine the interactive roles of all-trans retinoic acid (ATRA), Ets-1, Sp1, and histone

108 on the short half-life vitamin A metabolite, all-trans retinoic acid (atRA), in an amount sufficient

109 with phosphate-buffered saline (PBS), UDCA, all-trans retinoic acid (atRA), or UDCA and atRA by gava

110 e present standard of care, chemotherapy and all-trans retinoic acid (ATRA), results in a high propor

111 All-trans retinoic acid (atRA), the active derivative of

112 In response to challenge with all-trans retinoic acid (atRA), the balance of daughter

113 promoter and is stimulated by treatment with all-trans retinoic acid (ATRA), the biologically active

114 es for metabolism into an active metabolite, all-trans retinoic acid (atRA), where atRA is essential

115 or source of the immunoregulatory metabolite all-trans retinoic acid (ATRA), which may contribute to

116 mechanism-based screening, here we find that all-trans retinoic acid (ATRA)--a therapy for acute prom

117 Despite the great success of all-trans retinoic acid (ATRA)-based therapy, which resu

118 In this study, we present an effective model All-Trans Retinoic Acid (ATRA)-induced differentiation o

119 s depleted of Ajuba are highly sensitized to all-trans retinoic acid (atRA)-induced transcription and

120 Mutations in the all-trans retinoic acid (ATRA)-targeted ligand binding d

121 d substantially in the marrow and spleens of all-trans retinoic acid (ATRA)-treated C57BL6 mice, whil

122 investigated the gene expression profile of all-trans retinoic acid (ATRA)-treated human CD4(+) T ce

123 rated insensitive response to this effect of all-trans retinoic acid (ATRA).

124 emia activity and may restore sensitivity to all-trans retinoic acid (ATRA).

125 ctive up-regulation in the leukemic cells by all-trans retinoic acid (ATRA).

126 icrog (low-dose) or 1,000 microg (high-dose) all-trans retinoic acid (ATRA)/kg body weight in corn oi

127 PURPOSE Event-free survival following all-trans-retinoic acid (ATRA) -based therapy for acute

128 te promyelocytic leukemia (APL) treated with all-trans-retinoic acid (ATRA) and arsenic trioxide (ATO

129 PML-RARa-associated APL is sensitive to both all-trans-retinoic acid (ATRA) and arsenic trioxide (ATO

130 The use of all-trans-retinoic acid (ATRA) and arsenic trioxide, bot

131 Synergistic actions between all-trans-retinoic acid (atRA) and interferon gamma (IFN

132 tinct promoter P3, which can be activated by all-trans-retinoic acid (atRA) and other RAR/RXR selecti

133 hrome P450 CYP26 enzymes are responsible for all-trans-retinoic acid (atRA) clearance.

134 All-trans-retinoic acid (ATRA) combined with chemotherap

135 All-trans-retinoic acid (ATRA) did not stimulate osteocl

136 All-trans-retinoic acid (atRA) has been implicated in th

137 All-trans-retinoic acid (ATRA) has been shown to act phy

138 All-trans-retinoic acid (ATRA) has been shown to arrest

139 (AML), the use of the differentiation agent all-trans-retinoic acid (ATRA) has revolutionized the th

140 Treatment of APL with all-trans-retinoic acid (ATRA) induces disease remission

141 All-trans-retinoic acid (ATRA) induces growth arrest of

142 Although all-trans-retinoic acid (atRA) is a key regulator of int

143 All-trans-retinoic acid (ATRA) is a natural compound pro

144 All-trans-retinoic acid (ATRA) is an active vitamin A de

145 All-trans-retinoic acid (atRA) is an important morphogen

146 All-trans-retinoic acid (atRA) is the active metabolite

147 All-trans-retinoic acid (atRA) is the active metabolite

148 The all-trans-retinoic acid (atRA) isomer, 9-cis-retinoic ac

149 26 family is believed to be responsible for all-trans-retinoic acid (atRA) metabolism and eliminatio

150 Lcn2 KO mice exhibited a blunted effect of all-trans-retinoic acid (ATRA) on body weight and fat ma

151 The combination of all-trans-retinoic acid (ATRA) plus arsenic trioxide (AT

152 l compared efficacy and toxicity of standard all-trans-retinoic acid (ATRA) plus chemotherapy versus

153 ssing the estrogen receptor alpha (ERalpha), all-trans-retinoic acid (ATRA) receptor alpha (RARalpha)

154 We investigated the actions of all-trans-retinoic acid (atRA) signaling in pancreatic b

155 All-trans-retinoic acid (atRA) stimulates neurogenesis,

156 All-trans-retinoic acid (atRA) supports embryonic develo

157 ntained only about a 0.6 nm concentration of all-trans-retinoic acid (atRA) that is the most active n

158 successfully treated with therapy utilizing all-trans-retinoic acid (ATRA) to differentiate leukemic

159 ytic leukemia patients and cell lines during all-trans-retinoic acid (ATRA) treatment by using a miRN

160 All-trans-retinoic acid (atRA), an autacoid derived from

161 ly after recognition of the effectiveness of all-trans-retinoic acid (ATRA), anthracycline-based chem

162 Vitamin A derivatives, including all-trans-retinoic acid (ATRA), have a well-established

163 his defect can be overcome by treatment with all-trans-retinoic acid (ATRA), leading to complete clin

164 fects through the actions of its metabolite, all-trans-retinoic acid (ATRA), on gene transcription me

165 All-trans-retinoic acid (ATRA), retinol, retinalaldehyde

166 All-trans-retinoic acid (atRA), the active metabolite of

167 All-trans-retinoic acid (atRA), the major active metabol

168 Subsequent oxidation produces all-trans-retinoic acid (ATRA), which functions as a lig

169 tly, different statins were found to enhance all-trans-retinoic acid (ATRA)-dependent differentiation

170 nsformation and leukemogenesis, and inhibits all-trans-retinoic acid (ATRA)-induced AML cell differen

171 DR5) site in the OLFM4 promoter and mediates all-trans-retinoic acid (ATRA)-induced transactivation o

172 o several developmental genes, including the all-trans-retinoic acid (ATRA)-responsive ones, through

173 in the formation of the essential morphogen all-trans-retinoic acid (ATRA).

174 vous system require the vitamin A metabolite all-trans-retinoic acid (atRA).

175 lation of myeloid cell differentiation using all-trans-retinoic acid (ATRA).

176 re, the outcome of 155 patients treated with all-trans retinoic acid-based therapy on 3 clinical tria

177 beta-apo-8'-carotenal, 13-cis-retinoic acid, all-trans-retinoic acid, beta-carotene-5,6-epoxide, all-

178 Rdh10 catalyzes the first step of all-trans-retinoic acid biogenesis physiologically, conv

179 retinal dehydrogenases (critical enzymes for all-trans retinoic acid biosynthesis) and were significa

180 orms efficiently (V(m)/K(m)) in a pathway of all-trans-retinoic acid biosynthesis in cells and recogn

181 When differentiation was induced by all-trans retinoic acid, CEACAM6 expression strongly cor

182 We reported previously that all-trans-retinoic acid chemo-prevented carcinogenic tra

183 te promyelocytic leukemia model treated with all-trans retinoic acid combined with the histone-deacet

184 ng to neutrophils and in vivo treatment with all-trans retinoic acid decreased plasminogen binding to

185 ibroblasts in response to 5 toxic compounds (all-trans retinoic acid, dexamethasone, doxorubicin, 5'-

186 sfully demonstrated using both ibuprofen and all-trans retinoic acid; drugs with anti-inflammatory an

187 ndrites, and knocking down RARalpha prevents all-trans-retinoic acid effects on dendritic growth.

188 tion cycles with idarubicin, cytarabine, and all-trans retinoic acid either with VPA or without (STAN

189 of acute promyelocytic leukemia (APL) in the all-trans retinoic acid era.

190 nous ligands, such as 9-cis retinoic acid or all-trans retinoic acid, expands the activation of RXR t

191 de for vision as well as the biosynthesis of all-trans-retinoic acid for differentiation and developm

192 The major active retinoid, all-trans retinoic acid, has long been recognized as cri

193 ith granulocyte colony-stimulating factor or all-trans-retinoic-acid have shown improvement in decrea

194 ion of all-trans-retinol for biosynthesis of all-trans-retinoic acid, however, initial assays suggest

195 Consistent with the role of all-trans retinoic acid in inducing gut-homing T cells,

196 found that response to targeted therapy with all-trans retinoic acid in vivo was dependent on NB inte

197 idence that vitamin A uptake is regulated by all-trans-retinoic acid in non-ocular tissues of mice.

198 o produce visual chromophore in the eyes and all-trans-retinoic acid in other tissues.

199 All-trans retinoic acid increased CD38 levels and decrea

200 rmed by conventional western immunoblotting: all-trans-retinoic acid increased ELF3, topoisomerase II

201 cells with demethylating agent combined with all-trans-retinoic acid induced apoptosis.

202 uced macrophage differentiation, but blocked all-trans-retinoic acid induced granulocytic differentia

203 ls causes acute myeloid leukemia and impairs all-trans retinoic acid-induced granulocytic differentia

204 feron-induced mortality (GRIM)-19, as an IFN/all-trans retinoic acid-induced growth suppressor.

205 We found that the major vitamin A metabolite all-trans-retinoic acid induces histone acetylation at t

206 (PPAR) alpha, alone and in conjunction with all-trans-retinoic acid is capable of enhancing TFEB in

207 Administration of all-trans-retinoic acid led to a significant decrease in

208 dipose retinoid (retinol, retinyl ester, and all-trans-retinoic acid) levels were observed.

209 All-trans-retinoic acid may be an important molecular si

210 me myeloid leukemias respond dramatically to all-trans retinoic acid mediated differentiation therapy

211 Chiral pentamers of all-trans-retinoic acid molecules have been prepared on

212 Temporary discontinuation of all-trans retinoic acid or arsenic trioxide is indicated

213 at trigger PML-RARalpha degradation, such as all-trans retinoic acid or arsenic trioxide, restore nuc

214 All-trans retinoic acid or related compounds may also pl

215 this randomization were randomly assigned to all-trans-retinoic acid or not.

216 tion of SH-SY5Y human neuroblastoma cells by all-trans retinoic acid, or oxidative stress induced by

217 differentiation with 5-bromo-2'deoxyuridine, all-trans-retinoic acid, or IFN-gamma induced PML-nuclea

218 ll (Treg)-polarizing molecules TGF-beta1 and all-trans retinoic acid, particularly during states of i

219 vailable only in the context of conventional all-trans retinoic acid plus chemotherapy regimens.

220 sence or presence of the RAR-specific ligand all trans retinoic acid (RA).

221 Long-term treatment with all trans-retinoic acid (RA) induces neuronal differenti

222 s well as IL10 and the vitamin A metabolite; all-trans retinoic acid (RA [at-RA]) has been found to e

223 oth genes are transcriptionally activated by all-trans retinoic acid (RA) and display increased level

224 spinal cord phenotype using a combination of all-trans retinoic acid (RA) and epidermal growth factor

225 All-trans Retinoic acid (RA) and its derivatives are pot

226 Reduced generation of all-trans retinoic acid (RA) by CD103(+) intestinal dend

227 We demonstrate that all-trans retinoic acid (RA) induces FoxP3(+) adaptive T

228 60 model human myeloid leukemia cells, where all-trans retinoic acid (RA) induces granulocytic differ

229 We have previously shown that all-trans retinoic acid (RA) mediates activity blockade-

230 The major vitamin A metabolite all-trans retinoic acid (RA) not only enforces the gener

231 However, the effects of all-trans retinoic acid (RA) on cellular expression of V

232 pplication of active vitamin D3 (VD3) and/or all-trans retinoic acid (RA) on wild-type mouse skin ind

233 All-trans retinoic acid (RA) plays crucial roles in embr

234 mechanisms whereby the vitamin A metabolite all-trans retinoic acid (RA) promotes the formation of p

235 All-trans retinoic acid (RA) stimulates cellular prolife

236 ated the ability of the vitamin A metabolite all-trans retinoic acid (RA) to restore the defective im

237 Here, we report that all-trans retinoic acid (RA), a well-known developmental

238 Vitamin A and its active metabolite, all-trans retinoic acid (RA), regulate the antibody resp

239 rcinoma (EC) is relieved upon treatment with all-trans retinoic acid (RA), resulting in enhanced p53

240 Hox gene expression is activated by all-trans retinoic acid (RA), through binding to retinoi

241 sticity, in part by stimulating synthesis of all-trans retinoic acid (RA), which in turn increases AM

242 ndritic cells (DC) metabolize vitamin A into all-trans retinoic acid (RA), which is required to induc

243 with HtrA2 and augments cell death in an IFN/all-trans retinoic acid (RA)-dependent manner.

244 In all-trans retinoic acid (RA)-induced differentiation of

245 of glioblastoma stem-like cells (GBM-SCs) to all-trans retinoic acid (RA).

246 neuroblastoma cells following treatment with all-trans retinoic acid (RA).

247 ivation of retinoic acid receptor (RAR) with all-trans-retinoic acid (RA) ameliorates glucose intoler

248 hrome P450 enzyme Cyp26a1, which metabolizes all-trans-retinoic acid (RA) and thereby reduces RA leve

249 Many biological activities of all-trans-retinoic acid (RA) are mediated by the ligand-

250 APL cell treatment with all-trans-retinoic acid (RA) degrades the chimeric, domi

251 is study was to examine the possibility that all-trans-retinoic acid (RA) in the eye is a signal rela

252 All-trans-retinoic acid (RA) induces various anatomical

253 We have previously demonstrated that all-trans-retinoic acid (RA) induction of RIP140 constit

254 P26A1, a cytochrome P450 enzyme, metabolizes all-trans-retinoic acid (RA) into polar metabolites, e.g

255 All-trans-retinoic acid (RA) is a vitamin A metabolite t

256 This study explored the effects of all-trans-retinoic acid (RA) on cellular and biochemical

257 al (HBE) cells to evaluate stabilities after all-trans-retinoic acid (RA) or cycloheximide treatments

258 The vitamin A metabolite all-trans-retinoic acid (RA) regulates multiple biologic

259 All-trans-retinoic acid (RA) stimulates differentiation

260 , but not Tbx18 or NFATC1, is activated with all-trans-retinoic acid (RA) treatment of isolated chick

261 We found that all-trans-retinoic acid (RA) treatment of mouse epiphyse

262 We reported previously that all-trans-retinoic acid (RA) treatment prevented carcino

263 All-trans-retinoic acid (RA), a bioactive derivative of

264 We report herein that all-trans-retinoic acid (RA), an active metabolite of vi

265 Vitamin A metabolite, all-trans-retinoic acid (RA), induces cell growth, diffe

266 hat DGL-alpha and DGL-beta may contribute to all-trans-retinoic acid (RA)-induced neurite outgrowth i

267 We show here that all-trans-retinoic acid (RA)-mediated repression of HIV-

268 Whereas both are all-trans-retinoic acid (RA)-responsive in ES cells, the

269 nhibitory and pro-differentiating effects of all-trans-retinoic acid (RA).

270 tival epithelial (HCjE) cell line grown with all-trans-retinoic acid (RA).

271 LDH1A3 complexed with NAD(+) and the product all-trans retinoic acid (REA).

272 wth in vitro, whereas pharmacologic doses of all-trans retinoic acid repressed OTX2 expression and in

273 In contrast, treatment of apc mutants with all-trans retinoic acid rescued retinal differentiation

274 drugs should be considered for treatment of all-trans retinoic acid-resistant APL patients as well a

275 induce cell death and induces expression of all-trans-retinoic acid-responsive genes that can be blo

276 Short-term treatment of mice with all-trans retinoic acid resulted in increased PreB lymph

277 developmental signaling molecules including all trans-retinoic acid, Shh, bone morphogenetic protein

278 All-trans-retinoic acid stimulates dendritic growth in h

279 ation of the retinoic acid receptor agonist, all-trans-retinoic acid, suggesting that the ability of

280 human pulmonary artery smooth muscle cells, all-trans retinoic acid suppressed serotonin-induced cel

281 All -trans-Retinoic acid ( t-RA) regulates leukocyte dif

282 generate both all-trans-retinal (t-RAL) and all-trans-retinoic acid (t-RA) from the precursor all-tr

283 All-trans retinoic acid therapy of acute promyelocytic l

284 essed cell proliferation and synergized with all-trans retinoic acid to promote differentiation.

285 We recently demonstrated that all-trans retinoic acid (tRA) induces both NIS gene expr

286 Topical treatment of human skin with all-trans retinoic acid (tRA) induces EGFR ligands hepar

287 All-trans retinoic acid (tRA) induces NIS gene expressio

288 All-trans-retinoic acid (tRA) markedly induces NIS activ

289 All trans-retinoic acid treatment of A404 cells induced

290 vation of c-SRC as early as 15 min following all-trans-retinoic acid treatment in LA-N-5 cells.

291 y, early forced maturation of MDSC by either all-trans-retinoic acid treatment or active immunorecept

292 Utilizing in-vitro experimental models of all-trans retinoic acid triggered myeloid leukemia diffe

293 Both promoters are partially regulated by all-trans retinoic acid via RARA and other RARs.

294 d for CCR9 by cell sorting or culturing with all-trans retinoic acid, we measured chemotaxis, intrace

295 Isotretinoin is a pro-drug for all-trans retinoic acid, which can induce long-term remi

296 t-associated dendritic cells (DC) synthesize all-trans retinoic acid, which is required for inducing

297 s-retinaldehyde, the visual chromophore, and all-trans-retinoic acid, which is involved in the regula

298 Furthermore, treatment of NB4 cells with all-trans-retinoic acid, which promotes PML-RARalpha deg

299 nergistic effects of valproic acid (VPA) and all-trans retinoic acid with chemotherapy.

300 the retinoic acid receptor (RAR) compared to all-trans-retinoic acid, with select analogues also redu