ライフサイエンスコーパス: allenyl

1 A range of 1-allenyl-2-amino alcohols were obtained with excellent re

2 Rapid scrambling of axial chirality of allenyl acetates in the presence of Rh(I) catalysts enab

3 This asymmetric APKR of allenyl acetates is a rare example of a Type I DyKAT rea

4 e propargylic group is generally favored (vs allenyl addition; 89:11 to >98:2 selectivity); 1,5-enyne

5 rolin-2-ones, while similar treatment of the allenyl adducts affords 4-alkylidine- pyrrolidin-2-ones

6 ct is proposed in which the initially formed allenyl alcohol 3 undergoes dehydration to provide an al

7 lation of a series of aldehydes 1 to provide allenyl alcohol product 3 as a single diastereoisomer.

8 see eq 7), the other for the cyclizations of allenyl alcohols (see eq 11).

9 talyzed cyclization of N-allenyl carbamates, allenyl alcohols, and 2-allenyl indoles that possessed a

10 A new nickel-catalyzed allenyl aldehyde cyclization was developed in the approa

11 nd tertiary alkyl, as well as alkenyl, aryl, allenyl and alkynyl groups.

12 ves mixtures of alpha-substituted conjugated allenyl and beta,gamma-alkynyl deconjugated esters.

13 divergent Au-catalyzed cycloisomerization of allenyl and homopropargylic ketones into synthetically v

14 and enantioselective gamma-hydroamination of allenyl and propargyl esters with N-methoxy carbamate nu

15 Thermal rearrangements of 2-allenyl- and 2-alkynyl-3-(2-ethenylphenyl)-4,4-dimethoxy

16 Calculations of the C-Zn BDEs in allenyl- and propargylzinc species were performed with t

17 extrusion of a hydrogen radical, leads to an allenyl anion that is detected in the ESI-MS as [M - H -

18 Gold(I) complexes react with 4-allenyl arenes in an exo fashion to furnish vinyl-substi

19 A commercially available allenyl-boron compound or a monosubstituted allene may b

20 ecifically with formal SN2' pathways to give allenyl boronates.

21 talyzed C-C bond formations between allyl or allenyl boronic esters and acetals, ketals, or aminals h

22 ce of adducts resulting from the trapping of allenyl canonical forms was supported by DFT calculation

23 catalyzed intramolecular hydroamination of N-allenyl carbamates tolerated substitution at the alkyl a

24 Au-catalyzed cyclization of N-allenyl carbamates, allenyl alcohols, and 2-allenyl indo

25 Allenyl carbinol ester 3 isomerizes to an E,Z mixture of

26 ates tolerated substitution at the alkyl and allenyl carbon atoms and was effective for the formation

27 gated alkynyl carbonyls to the corresponding allenyl carbonyls is described.

28 A chiral pentafluorophenyl-gold(III) allenyl complex with the gold atoms coordinated to the g

29 luorophenyl-, and triphenylphosphine-gold(I) allenyl complexes were prepared in which the alpha carbo

30 At ambient temperature, the allenyl compounds undergo an electrocyclic cascade to gi

31 Allenyl-containing products are generated in up to 95% y

32 Previous studies have shown that the allenyl Cope rearrangement of 1,2, 6-heptatriene (1) to

33 re recently, the conformationally restricted allenyl Cope rearrangement of syn-7-allenylnorbornene (7

34 surface for the conformationally restricted allenyl Cope rearrangements of syn-5-propadienylbicylco[

35 e first reported examples of fully concerted allenyl Cope rearrangements.

36 es from the coupling reaction of alkenyl and allenyl cycloalkanols with aryl diazonium salts.

37 nce of the catalyst upon the geometry of the allenyl enolate formed in the addition step.

38 Interception of the transient allenyl enolate intermediate of the vanadium-catalyzed M

39 rride innate stereoelectronic effects of the allenyl enolate reactive intermediate.

40 he regiochemistry of bisfunctionalization of allenyl ester homologues remained controlled by the este

41 on resulting from covalent activation of the allenyl ester substrate.

42 catalyzed isomerization to the corresponding allenyl ester.

43 kynyl esters to alpha-substituted conjugated allenyl esters (racemic) through the use of strong amide

44 mples of a Michael-Stork enamine addition to allenyl esters and ketones.

45 lyzed regioselective bisfunctionalization of allenyl esters with boronic acids (nucleophiles) and ald

46 l cycloalkanones are added to functionalized allenyl esters, leading to a lactone intermediate that i

47 alkylcuprates with alpha,beta-ynoates, alpha-allenyl esters, or alpha.beta-enoates or enimides underg

48 additions of alpha-aminoalkylcuprates to the allenyl esters, while poor stereoselectivity results in

49 s and with alpha,beta-beta,gamma-unsaturated allenyl esters.

50 d deconjugated alkynyl esters and conjugated allenyl esters.

51 ones, and 4-alkylidineindolizidin-2-ones via allenyl esters; pyrrolin-2-ones, tetrahydropyrrolizin-2-

52 arbanions to the terminal position of methyl allenyl ether is associated with unusually low activatio

53 e propargyl ether group to the corresponding allenyl ether, followed by oxidative cleavage with N-met

54 clopentannelation reaction that makes use of allenyl ether-derived nucleophiles has been probed.

55 acetophenone to methyl propargyl and methyl allenyl ethers is considered.

56 philic addition to alkyl propargyl and alkyl allenyl ethers yielding, along with (Z)-monoadducts, up

57 Unprecedented allenyl gold complexes have been achieved starting from

58 substitutions that result in addition of an allenyl group (<2% propargyl addition) and formation of

59 After the distannylation of the allenyl group with hexamethylditin catalyzed by the Pd c

60 The addition of an allenyl indium intermediate to chiral N-tert-butanesulfi

61 roarylation reaction of beta-lactam-tethered allenyl indoles gives azeto-oxepino[4,5-b]indol-2-ones,

62 -allenyl carbamates, allenyl alcohols, and 2-allenyl indoles that possessed an axially chiral allenyl

63 2-Allenyl indoles underwent Au-catalyzed intramolecular hy

64 ction proceeds through the initial propargyl-allenyl isomerization followed by the cyclization into t

65 induced 6-benzannulation involving propargyl-allenyl isomerization of the dieneyne moieties in the co

66 icle, the AuCl3-catalyzed hydrofurylation of allenyl ketone, vinyl ketone, ketone, and alcohol substr

67 ms are observed, one for the cyclizations of allenyl ketones (see eq 7), the other for the cyclizatio

68 heletropic extrusion of CO with formation of allenyl ketones 4.

69 ion-metal carbene complexes, including alpha-allenyl ketones and amino-substituted heterocycles.

70 ld base, NEt(3), leading to the formation of allenyl ketones and propargyl ketones.

71 Aromatic allenyl ketones undergo a phosphine-promoted dimerizatio

72 -bromophenylmethylidenefuranones also afford allenyl ketones upon flash vacuum thermolysis, but in ad

73 d 2-furylthiophenes 16 by cyclization of the allenyl ketones.

74 Reaction of allenyl methyl ketone 4 with exo-enones afforded spirocy

75 In the case of an allenyl methyl ketone, cyclopentyl enamine addition led

76 ation promoted by coordination of gold(I) to allenyl moiety lacks a discernible intermediate despite

77 nyl indoles that possessed an axially chiral allenyl moiety occurred with transfer of chirality from

78 occurred with transfer of chirality from the allenyl moiety to the newly formed stereogenic tetrahedr

79 alytic methods for the addition of allyl and allenyl organoboron reagents to fluorine-substituted ket

80 um with an R(3) group oriented syn and sigma-allenyl palladium complexes.

81 nit on the oxindole or indole reacts with an allenyl-palladium species, formed from oxidative additio

82 sigma-bond formation in 4, not the terminal allenyl pi-bond MO.

83 wo least stable modes of coordination at the allenyl pi-system display reactivity that is intermediat

84 ive salts such as LiCl lead primarily to the allenyl product while the use of HMPA as a cosolvent giv

85 oup yields H(2)C=C=CFP(O)(OEt)(2) through an allenyl-propargyl resonance stabilized anion.

86 The first characterization of an allenyl radical by single crystal X-ray crystallography

87 yl)(amino)carbenes (CAACs) affords propargyl/allenyl radicals.

88 ves causes allylic rearrangements, propargyl-allenyl rearrangement, conversion of benzyl cyanates to

89 ieved from the reaction of the corresponding allenyl (S)-N-tert-butylsulfinimies through the followin

90 iates followed by 1,2-group migration to the allenyl sp carbon during cycloisomerization.

91 eric encumbrance of the terminal alkynyl and allenyl subsituents.

92 , nipecotic acid derivatives containing an N-allenyl substituent were synthesized with good yields us

93 oles to generate oxindoles bearing allyl- or allenyl-substituted quaternary centers.

94 Allenyl sulfinimines can be stereoselectively cyclized w

95 fones functioned as synthetic equivalents of allenyl sulfones under these conditions.

96 g ketone carbanion addition to propargyl and allenyl systems occurs with activation energies typical

97 Different 1,3-dipoles of allenyl-type were employed, giving different regioselect

98 and promotes highly selective addition of an allenyl unit (vs a propargyl group).

99 catalyzed [3,3] sigmatropic rearrangement of allenyl vinyl ethers by density functional theory calcul

100 e Lewis acid mediated Nazarov reaction of an allenyl vinyl ketone was intercepted by acyclic, 2-silyl

101 m Nazarov/cycloaddition process involving an allenyl vinyl ketone with a diene has been carried out u

102 3-etherate of a series of carbon-substituted allenyl vinyl ketones provided intermediates in which su

103 e near complete transfer of chirality in the allenyl-Zn-Brook rearrangement and the highly organized

104 alkynylation of acylsilanes, followed by an allenyl-Zn-Brook rearrangement and Zn-ene-allene (or Zn-

105 DFT calculations show that the allenyl-Zn-Brook rearrangement occurs in preference to t