ライフサイエンスコーパス: allergenic

1 st mite (HDM) allergen, Der p 1, is the most allergenic.

2 derstanding of why some foods are inherently allergenic.

3 ed from latex gloves, which were shown to be allergenic.

4 ns in cows' milk that has been identified as allergenic.

5 ey protein, is poorly digested and is highly allergenic.

6 low homology of Pin p 1 sequence with other allergenic 2S albumins from angiosperms, Pin p 1 contain

7 ds have been identified as being potentially allergenic, a minority of these foods cause the majority

8 ve carbohydrate determinants (CCDs) with low allergenic activity and 60% of the Swedish asymptomatic

9 nsitized Swedish patients and elucidated its allergenic activity and cross-reactivity with the dog li

10 llen allergens are major allergens with high allergenic activity and exhibit structural similarity wi

11 and BM326 showed almost completely abolished allergenic activity and induced significantly reduced T-

12 nsity to Phl p 1, which may explain the high allergenic activity and sensitizing capacity of this all

13 mbinant PreS fusion proteins were tested for allergenic activity and T-cell activation by means of Ig

14 d by >70% of HDM-allergic patients, has high allergenic activity and, therefore, must be considered a

15 Furthermore, rDer p 23 exhibited high allergenic activity as demonstrated by upregulation of C

16 rom peanut asymptomatic patients showed poor allergenic activity compared with IgE from peanut-allerg

17 eactivity and exhibited considerably reduced allergenic activity in basophil activation tests using b

18 We show that pollensomes exhibit allergenic activity in terms of patients' IgE-binding ca

19 The high allergenic activity of Der p 23 and its frequent recogni

20 low allergenic peanut components and by poor allergenic activity of peanut-specific IgE.

21 IgE reactivity and allergenic activity of the formulas were tested with ser

22 r allergens, we hypothesize that part of the allergenic activity previously ascribed to Amb a 1 is ra

23 o Ara h 2 peptide epitopes was analyzed, and allergenic activity was assessed by basophil activation

24 rmined by using circular dichroism analysis, allergenic activity was determined by testing IgE reacti

25 Allergenic activity was determined using basophil activa

26 owing 100-fold lower IgE binding and reduced allergenic activity was generated.

27 ogeneity showed a lack of IgE reactivity and allergenic activity when tested with sera and basophils

28 mmunoreactive CM components, IgE reactivity, allergenic activity, ability to induce T-cell proliferat

29 ed, which showed no relevant IgE reactivity, allergenic activity, and induced lower Der p 2-specific

30 in addition to the established reduction in allergenic activity, include the enhanced focusing of bl

31 ure and showed no IgE reactivity or relevant allergenic activity, indicating that Phl p 5 IgE epitope

32 ergenic extract is assessed according to its allergenic activity.

33 ed and analyzed regarding IgE reactivity and allergenic activity.

34 tificial allergens to evaluate their in vivo allergenic activity.

35 y of IgE epitopes on an allergen affects its allergenic activity.

36 orldwide problem because is a very important allergenic agent; it can be altered only by certain micr

37 olved in host defence against infectious and allergenic agents via enhancement of killing and clearan

38 cted to alter the spatiotemporal dynamics of allergenic airborne pollen and potentially increase occu

39 changes in the seasonal timing and levels of allergenic airborne pollen for multiple taxa in differen

40 impacts on aerobiology and allergy caused by allergenic airborne pollen.

41 In B. tropicalis, the most prevalent and allergenic allergens are in the order of Blo t 21, Blo t

42 Environmental proteinases are highly allergenic and are candidate inducers of airway Th2 resp

43 association with sensitization to the highly allergenic and cross-reactive tropomyosins Asc l 3, Blo

44 allergenic food; however, when food induced allergenic and immunologic reactions have been implicate

45 esults show that certain CM formulas without allergenic and low proinflammatory properties can be ide

46 DC-SIGN-binding glycoproteins in a panel of allergenic and non-allergenic foods.

47 so to be chemotherapeutic agents that may be allergenic and potentially carcinogenic, which represent

48 ross-reactivity between A. aegypti and other allergenic arthropods.

49 taiwana (biting midge) is the most prevalent allergenic biting insect in Taiwan, and 60% of the expos

50 have cloned and expressed genes encoding the allergenic brazil nut 2S albumin (Ber e 1) and the sunfl

51 However, many fungi are directly allergenic by colonising the respiratory tract or indire

52 how that an allergen from a food known to be allergenic can be transferred into another food by genet

53 New allergenic candidates, phosphoglycerate mutase and phosp

54 might well contribute to explain the potent allergenic capacity of these two clinically relevant all

55 ic reactions are any sources of protein with allergenic capacity.

56 Preliminary reports have demonstrated its allergenic capacity.

57 While allergenic challenge with a low-dose ovalbumin (OVA) onl

58 that the epidemiologic importance of O3 and allergenic cofactors can be underestimated by failure to

59 the food industry, being a potential hidden allergenic commodity.

60 of circulating IgE against HDM and the major allergenic components Der p1 and Der p2 was significantl

61 allows the detection of traces of DNA of the allergenic components in spite of an excess of the other

62 The dominant allergenic components of grass pollen are known by immun

63 revealed qualitative differences between the allergenic components of JGP and temperate grass pollens

64 dentify and immunologically characterize the allergenic components of the Panicoideae Johnson grass p

65 ra species varies according to the different allergenic components of the venom.

66 nvestigate the evolution of IgE responses to allergenic components of timothy grass and dust mite dur

67 aracteristics of cashew nut, the prevalence, allergenic components, cross-reactivity, diagnosis and m

68 testinal immune system in an immunogenic and allergenic conformation, allowing sensitization and indu

69 Inhalation exposure to the microbial and allergenic content of indoor dust is associated with adv

70 1 is a German cockroach allergen that shows allergenic cross-reactivity with American cockroach alle

71 e conflicting data regarding their antigenic/allergenic cross-reactivity, with no plant Cyp allergen

72 This information will aid in predicting allergenic cross-responses and eventually in determining

73 from Cat r 1-allergic individuals to fungal allergenic Cyps Asp f 11 and Mala s 6.

74 ining 3-linked core fucose, which is a major allergenic determinant on insect and plant glycoproteins

75 form various computations related to protein allergenic determinants and prepare the output HTML page

76 s repertoire has never been investigated for allergenic drugs.

77 data support the hypothesis that peanuts are allergenic due to inherent adjuvant activity and suggest

78 1A, but DE did not significantly modify this allergenic effect.

79 ith asthma may be due to its augmentation of allergenic effects, but the role of microRNA (miRNA) and

80 llenged them intranasally with short ragweed allergenic extract (SRW).

81 states that when measured, the potency of an allergenic extract is assessed according to its allergen

82 immunotherapy using depigmented polymerized allergenic extract of mixed grass pollen was performed o

83 bjective measure of stability of each lot of allergenic extract over time.

84 lenged intranasally with short ragweed (SRW) allergenic extract.

85 As of 2016, 19 allergenic extracts are standardized for potency in the

86 Allergenic extracts that have multiple immunodominant al

87 s would contribute to the standardization of allergenic extracts used for diagnosis and immunotherapy

88 tly approved treatments are avoidance of the allergenic food and administration of emergency medicati

89 approved treatments except avoidance of the allergenic food and treatment of accidental reactions.

90 Fish is an allergenic food capable of provoking severe anaphylactic

91 obiologically stable food base incorporating allergenic food ingredients manufactured at three sites

92 iew and meta-analyze evidence that timing of allergenic food introduction during infancy influences r

93 servational studies that evaluated timing of allergenic food introduction during the first year of li

94 ated with celiac disease risk, and timing of allergenic food introduction was not associated with oth

95 Regarding long-term management, avoiding the allergenic food or substituting an alternative was commo

96 ion with chronic or repeated exposure to the allergenic food protein, although the risks and potentia

97 ize pepsin stability to assess the safety of allergenic food proteins.

98 mine the association of reaction history and allergenic food with odds of physician diagnosis and tes

99 Since the Brazil nut is a known allergenic food, we assessed the allergenicity of the 2S

100 Soybean (Glycine max) is considered a major allergenic food.

101 Maize (Zea mays) is not considered a major allergenic food; however, when food induced allergenic a

102 signed them to the early introduction of six allergenic foods (peanut, cooked egg, cow's milk, sesame

103 lding or encouraging exposure to potentially allergenic foods after 4 months once weaning has commenc

104 tunately, many children develop tolerance to allergenic foods after a period of dietary elimination.

105 ses are a powerful tool to compare different allergenic foods and for informing policy on precautiona

106 sts, to establish threshold values for major allergenic foods and to analyse the socio-economic impac

107 erive threshold dose distributions for major allergenic foods and to elaborate the protein doses at w

108 of age, of at least some amount of multiple allergenic foods appears achievable and did not affect b

109 for around 6 months with no introduction of allergenic foods before 6 months of age.

110 Avoidance of highly allergenic foods beyond 4-6 months may not be effective

111 Eliciting doses (EDs) of allergenic foods can be defined by the distribution of t

112 For 7 allergenic foods double-blind, placebo-controlled food c

113 olysed egg products may be beneficial as low-allergenic foods for egg-allergic patients to extent the

114 elines already allow for the introduction of allergenic foods from 4 to 6 months of age irrespective

115 the introduction of peanut as well as other allergenic foods have evolved with the emerging evidence

116 t show the efficacy of early introduction of allergenic foods in an intention-to-treat analysis.

117 evaluated whether the early introduction of allergenic foods in the diet of breast-fed infants would

118 By 6 months of age, nonintroduction of the allergenic foods in the EIG was less than 5% for each of

119 ine threshold dose distributions for 5 major allergenic foods in the European population.

120 the effect of specific early introduction of allergenic foods is being investigated.

121 dies suggest that early regular ingestion of allergenic foods might reduce the risk of food allergy.

122 The influence of early exposure to allergenic foods on the subsequent development of food a

123 The age at which allergenic foods should be introduced into the diet of b

124 Genetic modification of allergenic foods such as apple has the potential to redu

125 zation of DC-SIGN-binding proteins in common allergenic foods such as peanut, soy, tree nuts, egg, an

126 Fish is one of the most common allergenic foods that should be accurately labelled to p

127 bility of the early introduction of multiple allergenic foods to exclusively breast-fed infants from

128 to establish reference doses for 11 commonly allergenic foods to guide a rational approach by manufac

129 Importance: Timing of introduction of allergenic foods to the infant diet may influence the ri

130 y by means of early introduction of multiple allergenic foods was dose-dependent.

131 restricts the advice on levels of unintended allergenic foods which should trigger precautionary labe

132 jects with significant IgE levels can ingest allergenic foods without incident.

133 introduction of solid foods, even so-called allergenic foods, does not appear to be one of these fac

134 For most allergenic foods, insufficient threshold dose informatio

135 rtunately, many patients accidentally ingest allergenic foods, which can result in severe anaphylacti

136 Shrimp are highly allergenic foods.

137 ycoproteins in a panel of allergenic and non-allergenic foods.

138 Fish is one of the most allergenic foods.

139 astfeeding with sequential introduction of 6 allergenic foods: cow's milk, peanut, hard-boiled hen's

140 urthermore, high-CO(2) plants produce a more allergenic form of urushiol.

141 Ac residue and the presence of a potentially allergenic fucose alpha1,3-linked to the innermost GlcNA

142 Their allergenic functionality was then assessed using cell-ba

143 ed with an increased concentration of summed allergenic fungal species, high total fungal concentrati

144 concomitant increased exposure to spores of allergenic fungi such as Aspergillus and Penicillium.

145 undant natural carbohydrate polymers, is non-allergenic, GRAS, and cheap.

146 Hereby, residue 5 could be identified as an allergenic hot spot in Bet v 1.

147 e assessed both safety and efficacy of a low allergenic hydrolysed egg (HydE) preparation used in a d

148 s can be broadly classified as irritative or allergenic in nature.

149 to fungal taxa considered to be irritant or allergenic in sensitive subjects, yeasts in the home had

150 he detection/quantification of soybean as an allergenic ingredient in processed meat products.

151 MS/MS method for multiplex detection of five allergenic ingredients in a processed food matrix is pro

152 Allergenic ingredients in pre-packaged foods are regulat

153 le methods are required for the detection of allergenic ingredients.

154 ith implantable medical devices that contain allergenic materials like nickel; however, other cutaneo

155 ssumed to provoke wheeze through irritant or allergenic mechanisms, little is known about the differe

156 nchial inflammation through nonallergenic or allergenic mechanisms.

157 ughout the world, where it occurs with other allergenic members of the cashew family (Anacardiaceae).

158 s demonstrate miRNA-mediated depletion of an allergenic milk protein in cattle and validate targeted

159 emonstrated that fungi are potent sources of allergenic molecules covering a vast variety of molecula

160 ion affect IgG responses to a broad array of allergenic molecules in early childhood.

161 evalence and geometric mean levels of IgG to allergenic molecules in nonsensitized children were lowe

162 foodborne, vegetable foodborne, and airborne allergenic molecules is profoundly dependent on the rout

163 these profiles with a mixture of recombinant allergenic molecules of P pratense previously proposed f

164 tract, 39 profiles of sensitization to the 8 allergenic molecules tested (cutoff, 0.35 kU/L) were ide

165 on to 24 foods, 14 inhalant allergens and 55 allergenic molecules; and confirmation of clinical react

166 simultaneous detection of three potentially allergenic mustard species commonly used in food: white

167 ostic methods use whole extracts, containing allergenic, nonallergenic and cross-reactive molecules.

168 The structure and stability of the allergenic nonspecific lipid transfer protein (LTP) of p

169 ibition and were not observed with other non-allergenic nucleoside reverse transcriptase inhibitors,

170 patients showed IgE toward one of the highly allergenic peanut allergens (Ara h 1-3, 6, 9).

171 African patients can be caused by IgE to low allergenic peanut components and by poor allergenic acti

172 Potentially allergenic peanut in food served as one example.

173 This is the first structure of an allergenic plant Cyp revealing high conservation of the

174 rative pollen lipid profiling of 22 commonly allergenic plant species by the use of gas chromatograph

175 t evaluating endogenous allergens for rarely allergenic plants (e.g. maize and rice).

176 sive study quantifying exposure to the major allergenic pollen families Betulaceae, Oleaceae, Poaceae

177 The allergenic pollen seasons of representative trees, weeds

178 ant exposure to environmental pollutants and allergenic pollens and having a unique conjunctival asso

179 The task force determined the in vivo allergenic potency (100000 JAU/ml) and Der 1 content (38

180 Allergenic potency correlated well among the three fract

181 ing conditions to reduce or even abolish the allergenic potency of cashew and pistachio.

182 but variable levels of Jun a 3 may alter the allergenic potency of pollens produced under different e

183 In vivo allergenic potency was determined by intradermal testing

184 ase and protease-free Ag fragments showed no allergenic potency, demonstrating that only active prote

185 rence HDM extract and determined its in vivo allergenic potency.

186 teins, and the present study evaluates their allergenic potential and clinical relevance.

187 Their allergenic potential needs to be established.

188 IgE-binding activity and allergenic potential of Der p 13 were examined by ELISA,

189 he vinification process, indicating that the allergenic potential of grape LTP is not diminished by t

190 basis for understanding the immunogenic and allergenic potential of ligand binding to Bet v 1 allerg

191 re, the connection between pollution and the allergenic potential of pollen has yet to be clearly def

192 The nitration can enhance the allergenic potential of proteins, which may contribute t

193 dification by air pollutants can enhance the allergenic potential of proteins.

194 to bind IgE after digestion and hence their allergenic potential.

195 d to produce modified hen's egg with reduced allergenic potential.

196 and at maturity mice were challenged with an allergenic preparation, OVA with alum (OVA-A).

197 HydE can be regarded as a safe, low allergenic product to use in children allergic to egg.

198 The PH obtained is a low allergenic product with high antioxidant capacity.

199 birch pollen allergen) as well as with other allergenic profilins.

200 he dimerization mechanism in Bet v 1 and its allergenic properties are so far poorly understood.

201 s investigation was to determine whether the allergenic properties of Ber e 1 and SFA8 reflected diff

202 This study assesses the allergenic properties of cashew and pistachio after ther

203 tion and enzymatic hydrolysis may reduce the allergenic properties of food by changing the protein st

204 ars and the effect of food processing on the allergenic properties of foods.

205 Despite the irritant and allergenic properties of fungi, early-life elevated dust

206 LTPs from different sources and evaluate the allergenic properties of LTPs from peach (Pru p 3) and p

207 he purpose of this study was to evaluate the allergenic properties of ovomucoid.

208 otentially useful as a coating to reduce the allergenic properties of peanut and cashew allergens.

209 We conclude that OA reduces the allergenic properties of peanut extract and cashew aller

210 After an era of only considering the allergenic properties of the infant diet and allergy out

211 The allergenic properties of the recombinant protein were te

212 to investigate the structural basis for the allergenic properties of this unusual protein.

213 ot clear whether this is due to its specific allergenic properties or to its higher concentration.

214 or Siberian hamster allergen was cloned, and allergenic properties were characterized, providing a ne

215 extract or cashew allergen and changes their allergenic properties.

216 is activity is relevant for developing their allergenic properties.

217 lly very similar, vary with respect to their allergenic properties.

218 in purified from pine nut and to analyze its allergenic properties.

219 (PPIase) activity by a PPIase assay and the allergenic property by an IgE-specific immunoblotting an

220 dritic or other cells by toxic chemicals and allergenic proteases, and suggest that the triggering of

221 31 species fall within the 10 most abundant allergenic protein domain families (EF-hand, Tropomyosin

222 conduct a molecular analysis of this highly allergenic protein.

223 mplicates fungi as both a relevant source of allergenic proteinases and a potential cause of asthma,

224 treatment time on soluble protein and major allergenic proteins (Ara h 1 and Ara h 2) of roasted pea

225 The new web-based Structural Database of Allergenic Proteins (SDAP) permits the user to quickly c

226 es, maintains the systematic nomenclature of allergenic proteins and publishes a database of approved

227 c extracts that have multiple immunodominant allergenic proteins are standardized with little or no i

228 Indeed, HDM is a carrier not only for allergenic proteins but also microbial adjuvant compound

229 oteins, lipoxygenases, storage proteins, and allergenic proteins during seed filling is also discusse

230 Plant chitinases are an example of food allergenic proteins for which structural analysis of all

231 ection of peanut protein Ara h 1, one of the allergenic proteins found in peanuts, has been demonstra

232 buffers, and (2) identification of specific allergenic proteins from extracts of incurred chocolate

233 Native and recombinant allergenic proteins from hen's egg and cow's milk were s

234 onsidered when investigating the presence of allergenic proteins in oils.

235 provides an approach to significantly reduce allergenic proteins in peanut product.

236 ion of chickpea likely cross-reacts with the allergenic proteins of pea and lentil.

237 By being in close proximity to allergenic proteins on the pollen surface when they inte

238 10 protein (PR-10) molecules are a family of allergenic proteins shared by many pollens (eg, birch an

239 The CM3 allergenic proteins were found to greatly vary among dif

240 were observed between samples, no toxins or allergenic proteins were found.

241 n addition, several previously characterized allergenic proteins were identified in the seed sample,

242 SDAP (Structural Database of Allergenic Proteins) is a web server that provides rapid

243 Among these allergenic proteins, Ara h 2 is one of the most commonly

244 cused on the identification of intracellular allergenic proteins, but have largely overlooked much of

245 ked to expose all milk components, including allergenic proteins, to food processing conditions.

246 milarity through sequence and structure with allergenic proteins.

247 evealed structural and functional aspects of allergenic proteins.

248 c stability and resultant IgE-binding of the allergenic proteins.

249 as beta-conglutin, and 8 were identified as allergenic proteins.

250 he sequences, structures and IgE epitopes of allergenic proteins.

251 uickly compare the sequence and structure of allergenic proteins.

252 lacks the characteristics found in potential allergenic proteins.

253 e effect on BLG digestion and could diminish allergenic reactions.

254 in enhancing or hindering the elimination of allergenic residues from wine.

255 This study investigated the presence of allergenic residues in both red and white wines fined wi

256 The possible presence of allergenic residues in wines treated with one of the pot

257 No detectable allergenic residues were found in any of the samples by

258 in promoting or hindering the elimination of allergenic residues.

259 body, both tests having high sensitivity for allergenic residues.

260 gen, the latter appears to promote only weak allergenic responses.

261 to be discovered to allow estimation of the allergenic risk for patients with peanut allergy and to

262 This includes a detailed analysis of allergenic risks, as the safety of allergic consumers ha

263 The study not only confirmed the highly allergenic role of Fraxinus, Betula and Poaceae pollens

264 g the first semester, suggesting a potential allergenic role of Parietaria pollination in this non-Me

265 We sought to search for potentially allergenic S aureus proteins and characterize the immune

266 ized by a high prevalence of atopy (61% with allergenic sensitization) and atopic dermatitis (78%).

267 d to analyse its ability to degrade the main allergenic sequences of this protein.

268 Moreover, peptides from hydrolysis of the allergenic sequences V41-K60, Y102-R124, C121-L140 and L

269 guidelines removed recommendations to delay allergenic solids.

270 If the modified plant is a common allergenic source (e.g. soybean), regulatory guidelines

271 GB are a new allergenic source with high prevalence of sensitisation.

272 directed against specific components from an allergenic source.

273 to 1 or more of 8 or 9 extracts from common allergenic sources, respectively.

274 Pollen lipids vary greatly among allergenic species and contain many molecules that have

275 ) is not as widely distributed as some other allergenic species, its pollen can induce serious pollin

276 eonatal AECs respond to pro-inflammatory and allergenic stimuli in vitro demonstrating their potentia

277 Allergenic strength was determined by skin tests with a

278 d food allergies is caused by cross-reacting allergenic structures shared by inhalants and foods.

279 Despite the myriad of potentially allergenic substances that can penetrate the skin, sensi

280 oteins considered as potential immunogens of allergenic T-cell responses have traditionally been limi

281 hether certain Aspergillus antigens are more allergenic than others, as was postulated previously.

282 Peel LTP is more allergenic than pulp LTP, but it is not clear whether th

283 (Juglans regia) are among the most commonly allergenic tree nuts, but little information is availabl

284 Novel allergenic tree species as well as tree pollen allergens

285 tree pollen allergies are mainly elicited by allergenic trees belonging to the orders Fagales, Lamial

286 We analyze the geographic distribution of allergenic trees, discuss factors pivotal for allergic s

287 nship of the allergen is essential to design allergenic variants with reduced IgE binding capacity bu

288 ultaneous detection of traces of potentially allergenic white mustard (Sinapis alba) and celery roots

289 of the molecular features that make proteins allergenic will help define new therapeutic targets aime