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3 dine, hypothesizing that this scaffold would allow access to a series of PAD2-selective inhibitors wi
5 by endowing RL systems with episodic memory, allowing them to (a) efficiently approximate value funct
7 technologies with a simple user interface to allow users to access large public datasets, such as tha
8 realistic molecular systems.Machine learning allows electronic structure calculations to access large
9 ommunities combined with in vivo experiments allows us to access an unprecedented diversity of genome
10 Such flexibility in dispersal patterns can allow individuals greater ability to acclimate to changi
12 ha-helical domains joined by a linker, which allows the trimer to adopt either a closed or an open co
13 alytic enantioselective transformations that allow convenient access to all stereoisomers of a given
14 equipped with an allorecognition system that allows them to respond directly to allogeneic grafts is
15 ncentration, conditions were identified that allowed the diffusion length to always exceed the film t
16 base is also equipped with basic tools which allow users to analyze the topology of arbitrary (bio)po
18 y schools (95% CI, 42.0%-57.0%) had teachers allow time for students to apply sunscreen at school, an
20 enomes like Sc2.0 are fully customizable and allow experimentalists to ask otherwise intractable ques
21 resource levels in a 2 x 2 factorial design, allowing us to assay colonization at both locality and p
22 cient spatiotemporal filtering method, which allows us to assess local thinning rates as low as 10 nm
24 d by EGFR-TKI resulted in the longest OS and allowed patients to avoid the potential neurocognitive s
25 onments require experimental techniques that allow a reaction to be initiated at a well-defined point
26 T (cHRT) is an alternative approach that may allow certain physiological outcomes to be achieved with
29 es and which are the downstream effects, may allow the syndrome of HFpEF to be distilled into distinc
30 fied the structures of key intermediates and allowed a complete mechanistic description to be present
32 The various approaches for diversification allowed one tetrasaccharide to be converted into 12 diff
34 ulation, especially for collision detection, allowing it to be simultaneously run and viewed on a lap
35 les thermometry with single-cell resolution, allowing neurons to be activated by exceptionally mild h
37 s, and solution matrixes were kept constant, allowing the proposed method to be reliably compared to
38 d on a log-log plot is very close to linear, allowing the unknown endogenous concentration to be esti
39 be overlapped with reference XANES spectra, allowing this method to be used for fingerprinting and l
40 but interact with charge and spin currents, allowing this moment to be manipulated purely by electri
45 the mechanism behind plate tectonics, which allows oceanic lithosphere to be subducted into the mant
48 together with PRNP gene sequencing the test allows the major prion subtypes to be differentiated in
49 use of fast-response, pressure-driving pumps allows the microfluidic flow to be quickly and accuratel
50 able covalent functional shell, Tube(wedge)2 allows the semiconducting conduction pathway to be modul
51 ough the use of fluorochrome labelled probes allows the target molecules to be detected by measuring
52 rforming 96-CBS extractions at the same time allows the total analysis time to be reduced to less tha
53 AAA PAS assumes an unusual conformation that allows this short motif to be bound directly by both CPS
56 s as well as relevant transcription factors, allowing us to better understand cell-type-specific regu
57 n of the GlcNAc-1-phosphotransferase enzyme, allowing them to bind receptors and traffic to endosomes
58 Additionally, the labile carboxylate group allows water to bind early in the catalytic cycle, allow
59 omoter recognition by sigma(N) The structure allowed us to build and refine an improved sigma(N)-holo
60 ppressed recombination is favored because it allows associations to build up between haploid-benefici
62 rified using small angle x-ray spectroscopy, allows us to calculate the heat released in this process
63 nd is a generalization of previous work that allows us to calibrate between a target distribution and
64 nent is an integrated relational design that allows the flexibility to capture any type of electronic
65 ived samples, and will therefore potentially allow the identification of cell-to-cell communication m
66 population of cells within a larger culture, allowing native cell-to-cell contact and communication e
74 ransgenerational epiallelic stability, which allowed us to classify chromosomal targets of epigenetic
75 have remarkable visual cognitive abilities, allowing them to classify visual patterns by common feat
76 e suggest that this sensitive sense of smell allowed the turkey vulture to colonize biomes that are s
79 the presence and absence of molecular oxygen allow us to conclude that the imidazolium salts is cruci
80 evidence in the context of experimental data allowed us to conclude that three chemosensory pathways
81 Differential gene-expression analysis has allowed us to confirm the relevance of these targets for
82 at continuous PM-to-ER cholesterol transport allows ER to constantly monitor PM cholesterol levels, a
83 s of the binding preferences of 400 peptides allowed us to construct a position-specific scoring matr
84 sin and TGF-beta receptor II (TbetaRII) that allows moesin to control the surface abundance and stabi
85 gineer the thermal conductivity of materials allows us to control the flow of heat and derive novel f
86 e sequential vapor deposition growth process allowed us to cool the existing 2D crystals to prevent u
89 d, while directly measuring the droplet size allows the user to define the more meaningful parameters
91 Here, the authors develop a witness which allow them to demonstrate entanglement between millions
93 odels for the larval, pupal and adult stage, allowed us to describe the morphogenetic changes shaping
94 able iterative genome engineering, Millstone allows users to design oligonucleotide libraries and cre
95 -ESI-MS of <0.02% of the single-cell content allowed us to detect approximately 230 different molecul
96 ellular protein content on the cell surface, allowing T cells to detect foreign or mutated peptides.
97 2-diphenyl-1-picryl-hydrazyl-hydrate), which allowed us to determine the ability to scavenge free rad
98 s combined with first-principles calculation allows us to determine that zone I displays an orthorhom
99 periments with intact human embryos must not allow them to develop beyond 14 days or the appearance o
100 generation of a drug gradient concentration, allowing exposure of cancer cells to different doses, an
101 the posttranslational modification of GRP78, allows cells to differentially regulate specific protein
104 ons found in constitutive Drd2(-/-) mice and allowed us to directly evaluate the participation of D2R
105 itioning, context pre-exposure facilitation, allows us to directly test the relationship between nove
106 udes a convolutional neural net pipeline and allows us to discriminate between normal and human breas
108 emble (GDBT) was applied to the samples that allowed us to distinguish between different genders, eth
109 nder on- and off-resonant pumping conditions allows us to distinguish between the loss of electronic
111 ersion and reversion of Pfr back to Pr, thus allowing Phys to dynamically measure light, temperature,
112 ve also shared a 'plug and play' pipeline to allow other researchers to easily use these algorithms o
113 -based platform that fosters team science by allowing collaborating research groups to easily store,
114 his need motivated us to develop a tool that allows investigators to easily identify regions with epi
115 adjust the configuration of the respirome to allow the organism to efficiently respire nitrate withou
116 he Fragment Network is a graph database that allows a user to efficiently search chemical space aroun
117 tory cortical functional separation that may allow multiple, specialized processing circuits to emerg
119 ance of gamma-band network oscillations, and allowed treated eFSE rats to encode and retrieve spatial
121 ntral side breaks the Dorsal/Cactus complex, allowing Dorsal to enter the nucleus to regulate target
122 ell, this binding also brings B-Raf to Rap1, allowing Rap1 to couple to ERKs through B-Raf binding to
123 e small changes in the capsid structure that allow the endocytosed virus to escape from the endosome,
124 of-function phenotype, suggesting that Myt1l allows newborn neurons to escape Notch activation during
127 odel of immune dysregulation that ostensibly allows the organism to evade clearance mechanisms and es
129 and after a 7 d monocular deprivation, which allowed us to examine both the depression component (Dc-
130 s occurred during a 3-year field experiment, allowing us to examine their effects on the response of
131 s and intraspecific phenotypic variation may allow pikas to exist in areas outside those predicted by
135 ect of the ecology of highly mobile animals, allowing populations to exploit spatially or temporally
136 wledge on long noncoding RNAs in C3 cereals, allowing the Brachypodium community to exploit these res
138 s to be followed across multiple studies and allow us to explore patterns of diversity at an unpreced
141 lls are differentiated, and that this effect allows a more precise response to external signals.
142 rk, we develop a simple variational approach allowing one to find the best possible counterdiabatic p
144 w-compression room-temperature synthesis may allow diverse molecular monomers to form single-crystall
145 ieving the most applicable analytic tools by allowing them to formulate their questions as free text.
146 ers are not necessarily required to pay any, allowing them to free-ride on the proposal investment co
147 udes communication between organelles, which allows them to function and adapt to changing cellular e
148 quality assessment needs to be maintained to allow the nephrology community to further bridge the qua
151 the brain operates locally in a CAS regime, allowing it to have an unlimited number of dynamical pat
152 ese highly electron-withdrawing substituents allow for polymerization of ethylene to higher molecular
153 ession is driven by IL-6/STAT3 signaling and allows MM cells to hijack R-spondins produced by (pre)os
157 ed a cell free antigen processing system and allowed the system to identify the hierarchies among pot
159 (ANOVA) and multivariate analyses (OPLS-DA) allowed us to identify new potential volatile markers re
161 son with control, uninfected livers and HCC, allowing us to identify pre-neoplastic epigenetic and tr
162 ulations at the level of individual hexamers allows us to identify a new, to our knowledge, mechanism
167 on in stomatal and mesophyll conductance may allow a plant to improve water-use efficiency without ne
169 developed a novel computational method that allows us to impute drug response in very large clinical
170 ly compliant criteria for sequence selection allows them to be modified to incorporate protease susce
171 perceived attractiveness and trustworthiness allowed the authors to incorrectly attribute many findin
173 ional definition at the network level, which allows us to infer the economic well-being of individual
174 RAS and SOS, which leads to bistability and allows for switch-like responses to inputs, is nested wi
175 pid cargoes cooperate to activate myosin VI, allowing myosin VI to integrate Ca(2+), lipid, and prote
176 the unique structural features of formoterol allow it to interact with the beta2AR to activate the Gb
177 that generates mRNAs with different 3'-ends, allowing them to interact with different sets of RNA reg
178 nduced dissociation of the Axin/GSK3 complex allows SIAH to interact with Axin not associated with GS
179 5-HT hydroxyl group and lipid headgroups and allows 5-HT to intercept reactive oxygen species, preven
180 ys with nanometer-scale spatial density that allow the quantum dots to interfere with each other and
183 esolution and dating accuracy of this record allow us to investigate how rainfall in the region respo
185 ve fields of these neurons have been mapped, allowing us to investigate how well they can support suc
186 d regime (Phi << 0.15 for all measurements), allowing us to isolate the effect of immobilization on e
187 x form, a conformation for domain switching, allows FIN219 to switch to its high-affinity mode and th
188 model of translocation in which ATP binding allows a Vps4 subunit to join the growing end of the hel
193 Raman spectroscopy (CARS) microspectroscopy allowed us to locally identify acylglycerols as the main
198 transient energy stress, and AMPK activation allows cells to manage this energy stress for proliferat
200 genome, we achieve 55-fold genome coverage, allowing us to map autonomous promoter activity genome-w
201 ded mutant green fluorescent proteins, which allowed us to measure the rates of selectively neutral m
204 crobiomes at appropriate phylogenetic scales allows us to model their evolution along the mammalian t
207 r, extant plant trait distributions will not allow extrapolations to novel community assemblages in f
209 al Cancer Institute's 60-cell line panel and allowed us to obtain an X-ray co-crystal structure of th
210 breathing has evolved in many fish lineages, allowing animals to obtain oxygen in hypoxic aquatic env
211 technique for the MWCNTs is developed, which allows us to obtain more accurate and reliable measured
212 ents, quinone and hydroquinone groups, which allow the enantiomerization to occur via redox-interconv
213 We carried out an evolution experiment, allowing for coevolution to occur, with the entomopathog
214 proved protection against amalgam saturation allows Hg disc-wells to operate safely in highly concent
215 and N2 fixation increased in the N2 fixers, allowing them to outcompete the non-N2 fixers regardless
218 behavior, where cognitive control processes allow us to override well-learned stimulus-response (S-R
220 rochaites LA0407 and in SC S. arcanum LA2157 allows S. lycopersicum pollen tubes to penetrate to the
221 he software system is robust, free, and will allow researchers to perform comparative evaluation of A
222 p. displays a quantifiable pulsing behavior, allowing us to perform long-term behavioral tracking.
225 rimarily by local environmental factors that allow relict populations to persist despite regionally u
227 thin, nutrient-enriched Phytagel matrix that allows pixel to pixel measurement of the distribution of
228 rasting patterns of modulatory effects could allow PMd and PMv to play distinct functions for the con
230 ow how a toxic equivalence (TEQ) calculation allows use of the qAOP to predict effects of another, un
231 ynthetic methods available in the literature allow one to prepare mono- and diheteroporphyrins and th
233 ctional approaches such as BH3 profiling may allow us to prioritize novel-agent combinations for furt
234 lar force sensors, acting as a genome proxy, allow us to probe the pathways through which a viromimet
235 lving secondary phosphines with hydrosilanes allowed the heterodehydrocoupling reaction to proceed ef
237 om being eliminated by the immune system and allows disease to progress from a very early stage to a
238 The newly reported equilibrium data also allow us to propose rate constant values for some hydrol
239 lating both anabolic and catabolic pathways, allow us to propose the hypothesis that SIRT1 may actual
240 tron cryo-microscopy of acidified hantavirus allows us to propose a model for endosome-induced reorga
241 r some of the characters, our reconstruction allows us to propose a new plausible scenario for the ea
242 ace nitrate concentration in this region and allow us to quantify the degree and temporal variability
244 experimental maize plots in western Kenya to allow us to quantify the response function relating NO f
245 plication of distortion/interaction analysis allows us to quantify the increased affinity of Au-catal
246 Here, we propose a modelling framework that allows us to quantitatively describe the timing of calci
247 steric contacts in the ligand binding sites, allowing us to rank the energetic contributions of these
249 paCOS using quantitative mass spectrometry, allowing one to rapidly analyze the substrate specificit
250 rk reports on a semiempirical treatment that allows one to rationalize and predict experimental condi
251 s so that surface Zn transforms into ZnO and allows ZnCu to reach the activity of ZnO/Cu with the sam
253 g fragments could prevent species losses and allow locally extinct species to recolonize former habit
254 the depletion of Ag NPs in the growth medium allowed the fungus to regain completely its ability of a
255 e CPK28 for Ca(2+) activation and might also allow CPK28 to remain active when Ca(2+) levels are low.
258 are micrometres and with up to 8,704 pixels, allowing us to render images such as the Mona Lisa and a
263 ms of turnover rate and activity, altogether allowing the cell to robustly tune its ZDHHC6 activity.
264 suite of services and web applications that allow users to select regions of interest in whole slide
266 ver, this media values individual expertise, allowing scientists to serve as a "Nerd of Trust" for th
268 Gene-specific expansion of the genetic code allows for UGA codons to specify the amino acid selenocy
272 of "differential-conductance mapping", which allows us to suppress quantum corrections to reveal the
273 ave selected for the precise traits that now allow pathogenic enterococci to survive desiccation, sta
275 post-translational modifications/mechanisms, allowing them to synthesize primarily G3P or glycerol de
276 nd optimization in structured architectures, allowing us to systematically dissect how brains learn.
278 in constrained laboratory settings, but also allows researchers to tackle real-world problems, such a
279 or nurse's aide to perform non-nursing tasks allows registered nurses to take on more complex patient
280 mproved methods to the hydrogel process will allow researchers to target smaller biological features
281 elated cost concerns prior to donation might allow transplant centers to target financial support int
283 ethod, the BLAST source code was modified to allow the researcher to pass to the program the number o
284 usage of l-Cysteine as a food additive isn't allowed in wheat flour according to the Turkish Food Cod
285 tion, a regioselective fluorination reaction allows access to the desired 3'-fluoro-3'-deoxytetrose m
288 30, 2012, the study protocol was amended to allow crossover from control to trastuzumab emtansine af
289 ons respond predictably to surface mutation, allowing us to tune and intermix the protein's behavior
290 ps, complemented with genetic perturbations, allowed us to uncover TRUB1 and PUS7 as the two key PUSs
294 stations documented using multimodal imaging allow us to use the eye as a window to the systemic infe
295 ependent malonate decarboxylase (MDC), which allows them to use malonate as the sole carbon source.
296 enotype contributes to metabolic plasticity, allowing cancer cells to adapt to various microenvironme
298 dence for this and need neural measures that allow us to watch this retrieval into working memory unf
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