ライフサイエンスコーパス: allylic

1 cyclization step is found to be governed by allylic 1,2-strain arising from the interaction of the N

2 The versatile synthetic utility of both the allylic acetate and enal products accessible through thi

3 is a three-component coupling that joins an allylic acetate, and indole and an organo-B(pin) species

4 anol-mediated reductive coupling of branched allylic acetates 1a-1o with formaldehyde to form primary

5 The boronate reacts with allylic acetates in the presence of (BINAP)Pd catalysts

6 tic asymmetric fluoroenolate alkylation with allylic acetates.

7 Stille cross-coupling leads to a nonracemic allylic alcohol as a prerequisite for the introduction o

8 reducing reagent gave a very functionalized allylic alcohol derivative in 86% yield.

9 hydes and allenes, providing silyl-protected allylic alcohol derivatives possessing a terminal methyl

10 Using this method, a number of allylic alcohol derivatives were efficiently obtained wi

11 The racemic allylic alcohol substrates can be converted to the enant

12 al beta-alkynyl carbonyl compounds employing allylic alcohol substrates in contrast to more tradition

13 productive CM coupling, the sphingosine head allylic alcohol was protected with a cyclic carbonate mo

14 are generated from the reaction of a second allylic alcohol with high selectivity in moderate to goo

15 (eta(2)-Allylic alcohol)iridium(I) and (eta(3)-allyl)iridium(III

16 t contain a carboxylic acid, an aldehyde, an allylic alcohol, an aryl olefin, an alpha substituent, o

17 -catalyzed strategy for the isomerization of allylic alcohols and allylic ethers has been developed.

18 s to deliver a range of synthetically useful allylic alcohols and amines in high enantiopurity.

19 hothiolate complex and afford trisubstituted allylic alcohols and ethers in up to 81% yield and >98%

20 of thiophiles, the sulfenate is trapped, and allylic alcohols are obtained under mild conditions.

21 erived from Katsuki-Sharpless epoxidation of allylic alcohols as initiating groups for cationic cycli

22 -propanol (HFIP), polyene cyclizations using allylic alcohols as initiators gave the desired cyclized

23 lization, owing to the utility of enones and allylic alcohols as versatile intermediates, and their p

24 ic enantioselective dichlorination of simple allylic alcohols is described.

25 Under these conditions, deoxyfluorination of allylic alcohols is effected with high chemoselectivity

26 ective Ir-catalyzed isomerization of primary allylic alcohols is reported.

27 stereochemical information contained in the allylic alcohols is transferred to the ketone products.

28 s enable the synthesis of either (Z)- or (E)-allylic alcohols regarding the order of introducing coup

29 noallylation step of amines with substituted allylic alcohols that proceeds to yield the monoallylate

30 enantioselective isomerization of secondary allylic alcohols to access ketones with a alpha-tertiary

31 ion between beta-iodoenamide derivatives and allylic alcohols to generate beta-allyloxyenamide deriva

32 A ferrocenium boronic acid salt activates allylic alcohols to generate transient carbocations that

33 olecular coupling of oxygen nucleophiles and allylic alcohols to give beta-aryloxycarbonyl compounds

34 al phosphoric acid catalyzed fluorination of allylic alcohols using aryl boronic acids as transient d

35 ctive arylative semipinacol rearrangement of allylic alcohols using diaryliodonium salts is reported.

36 Treatment of crude gamma,gamma-disubstituted allylic alcohols with NaOH, followed by acidification, a

37 n allylic substitutions of branched, racemic allylic alcohols with various nucleophiles.

38 A broad scope of phenols, various allylic alcohols, and an alkyl hydroperoxide are viable

39 antioselective bromochlorination reaction of allylic alcohols, employing readily available halogen so

40 r delta-chiral amines from readily available allylic alcohols, esters and ethers using a reductive re

41 strate classes, including 4-pentenoic acids, allylic alcohols, homoallyl amines, and bis-homoallylami

42 sformations that directly generate acyclic Z allylic alcohols, including products that contain a hind

43 on of variously substituted allenamides with allylic alcohols.

44 ma-disubstituted or beta,gamma-disubstituted allylic alcohols.

45 ible with all classes of alcohols (benzylic, allylic, aliphatic), mediate efficient lactonization of

46 rst examples of Cu-catalyzed gamma-selective allylic alkenylation using organozinc reagents are repor

47 ications in both copper-catalyzed asymmetric allylic alkylation and copper-catalyzed asymmetric boryl

48 Preliminary studies on the asymmetric allylic alkylation are promising.

49 the indole C3 position greatly improved the allylic alkylation chemistry and enabled a highly effici

50 (DHPI) substrates in Pd-catalyzed asymmetric allylic alkylation chemistry facilitates rapid access to

51 nd highly enantioselective rhodium-catalyzed allylic alkylation of allyl benzoate with alpha-substitu

52 ymmetric palladium-catalyzed decarboxylative allylic alkylation of differentially N-protected piperaz

53 The highly enantioselective asymmetric allylic alkylation of Morita-Baylis-Hillman carbonates w

54 A highly enantioselective rhodium-catalyzed allylic alkylation of prochiral alpha,alpha-disubstitute

55 regio- and stereospecific rhodium-catalyzed allylic alkylation of tertiary allylic carbonates with a

56 tereo-, and regioselective iridium-catalyzed allylic alkylation reaction of prochiral enolates to for

57 elective palladium-catalyzed decarboxylative allylic alkylation reaction using a novel bisphosphine l

58 constant) in palladium-catalysed asymmetric allylic alkylation reactions has proved to be extremely

59 owed by (2) decarboxylative enantioselective allylic alkylation serves as a novel strategy to in effe

60 st highly enantioselective iridium-catalyzed allylic alkylation that provides access to products bear

61 ied approach featuring a key decarboxylative allylic alkylation to access a crucial and highly conges

62 Our strategy incorporates an asymmetric allylic alkylation to construct the tert-alkyl aryl ethe

63 ique palladium(0)-catalyzed branch-selective allylic alkylation.

64 /alpha-alkylation and palladium(0)-catalyzed allylic alkylation.

65 tioselective acrylate addition or asymmetric allylic alkylation.

66 Enantioselective Pd-catalyzed allylic alkylations of dihydropyrido[1,2-a]indolone (DHP

67 highly enantioselective palladium-catalyzed allylic alkylations with benzylic nucleophiles, activate

68 that provides access to products bearing an allylic all-carbon quaternary stereogenic center has bee

69 these have been used for the preparation of allylic amide derived 2H-chromenes using an Overman rear

70 The allylic amide derived 2H-chromenes were converted to the

71 lyze the addition of diaryliodonium salts to allylic amides in excellent ee.

72 N-arylamines based on a palladium-catalyzed allylic amination has been developed.

73 s undergo alternative oxidative amination or allylic amination pathways, and these reactions will als

74 n competitive formation of aziridination and allylic amination products.

75 h2)2Pd(eta(3)-methallyl) catalyst 1 used for allylic aminations.

76 diates and enable the divergent synthesis of allylic amine and enamine derivatives, which are of sign

77 cal strategy for the synthesis of high-value allylic amine building blocks that does not require the

78 The desired enantiomer of the final allylic amine can be synthesized by choosing the sulfiny

79 ed to rationalize the stereocontrol in these allylic amine formation reactions, and evidence is provi

80 leads toward the formation of (Z)-configured allylic amine products.

81 - and ruthenium-free approaches to protected allylic amines and alkyl nitriles under photoredox condi

82 By this reaction, a range of cyclic allylic amines and vicinal amino alcohols have been prep

83 ctive synthesis of tri- and tetrasubstituted allylic amines based on Pd-catalyzed conversion of allyl

84 ith vinyl bromide electrophiles and delivers allylic amines in excellent yields (up to 99%).

85 d catalyst bearing a PHOX ligand, generating allylic amines in up to 97:3 er.

86 , which undergoes hydroamination to generate allylic amines instead of the enamine or imine products

87 tereoselective synthesis of multisubstituted allylic amines remains an inspiring target.

88 ess to both enantiomers of the corresponding allylic amines using the same catalyst enantiomer.

89 Primary allylic amines with enantiomeric excesses from 97 to >99

90 phos ligand, hydroamination generates chiral allylic amines with high regio- and enantioselectivity.

91 observed in recent years in the synthesis of allylic amines, which are important building blocks in s

92 sses are effective toward the preparation of allylic amines, with limited potential to introduce thre

93 oviding access to enantioenriched, protected allylic amines.

94 ed to convert alkyls into amino alcohols and allylic amines.

95 reveal that the cyclization, followed by 1,3-allylic amino dehydroxylation, is preceded by urea forma

96 precatalyst (FurCat) to promote Pd-catalyzed allylic ammonium salt generation from the allylic phosph

97 yzed enantioselective [2,3]-rearrangement of allylic ammonium ylides is described.

98 e report the in situ preparation of reactive allylic and benzylic boronic acids, obtained by reacting

99 iron phthalocyanine-catalyzed alkylation of allylic and benzylic C(sp(3))-H bonds.

100 intermediate, and differential activation of allylic and homoallylic alcohols in the analogues, follo

101 Allylic and homoallylic amines were formed in moderate y

102 Bisubstrate analogues containing the allylic and homoallylic substrates were synthesized by j

103 The preparation of enol and allylic and propargylic alcohol motifs is discussed, hig

104 saghi protocol, stereoselective reduction of allylic and propargylic ketones using Noyori's catalyst,

105 enes and radical substitution reactions with allylic and vinylic bromides and chlorides were examined

106 bon cross-coupling of Grignard reagents with allylic and vinylic bromides.

107 titution reactions of tertiary radicals with allylic and vinylic halides is described.

108 hydroxyl radicals that selectively abstract allylic and/or bis-allylic H atoms.

109 ld, amide-directed fluorination of benzylic, allylic, and unactivated C-H bonds mediated by iron.

110 sine to L-beta-lysine by LAM, via the stable allylic anhydroadenosyl radical (anAdo*).

111 Formation of an intimate ion pair between an allylic anion and the conjugate acid of the base results

112 contemplated as allyl electrophile donor for allylic arylation via pi-allyl palladium intermediate us

113 pylsilyl enol ether and functionalized as an allylic azide.

114 n pathway in a dynamic kinetic resolution of allylic azides.

115 pha C-H bonds in alcohols in the presence of allylic, benzylic, alpha-C=O, and alpha-ether C-H bonds.

116 Disubstituted allylic bis-imidates undergo Lewis acid catalyzed or spo

117 copper catalyst, these reagents reacted with allylic bromides derived from Morita-Baylis-Hillman alco

118 selective reductive transposition of primary allylic bromides is catalyzed by a biphilic organophosph

119 ymmetric alkylation of anthrones with cyclic allylic bromides using quinidine- or quinine-derived cat

120 iously unachievable Co-catalyzed coupling of allylic bromides with Grignards to linearly coupled alph

121 d N-sulfonamides undergo a Rh(III)-catalyzed allylic C(sp(3))-H activation followed by insertion with

122 a sodium amide has been exploited for formal allylic C(sp(3))-H bond activation of alkenes under mild

123 al Pd-catalyzed aerobic oxidation reactions: allylic C-H acetoxylation of terminal alkenes and intram

124 site-selective second arylation by directed allylic C-H activation giving stereoselectively anti-gam

125 A method for catalytic intermolecular allylic C-H amination of trans-disubstituted olefins is

126 An efficient aerobic linear allylic C-H amination reaction is reported under palladi

127 accomplish a mild, broadly effective direct allylic C-H arylation.

128 tocols for direct oxidation and amination of allylic C-H bonds (that is, C-H bonds where an adjacent

129 The oxidative cleavage of benzylic and allylic C-H bonds using DDQ can be coupled with an intra

130 ger amide N-H bond in the presence of weaker allylic C-H bonds, a selectivity that is uncommon in con

131 ailable materials, and represents a scalable allylic C-H oxidation (demonstrated on 100 grams), enabl

132 ve enyne cyclization and a late-stage double allylic C-H oxidation as well as adapted Luche reduction

133 been accomplished by palladium(II)-catalyzed allylic C-H oxidation from terminal olefin precursors.

134 ployed to effect a chemo- and regioselective allylic C-H oxidation in the presence of four oxidizable

135 The allylic C-H oxidation reaction proceeds with the broades

136 ore recently, the catalytic enantioselective allylic carbon-hydrogen oxidation of alkenes has streaml

137 ave been discovered for the enantioselective allylic carbon-hydrogen oxidation of simple alkenes with

138 generated from the oxidative addition of the allylic carbonate, likely activates the enol silanes to

139 A variety of cyclic and acyclic allylic carbonates are competent electrophilic partners

140 les in the iridium-catalyzed substitution of allylic carbonates is described for two processes.

141 ion of substituted spiroketals from racemic, allylic carbonates is reported, which enables the instal

142 ium-catalyzed allylic alkylation of tertiary allylic carbonates with alkenyl cyanohydrin pronucleophi

143 he reaction between propargylic alcohols and allylic carbonates, engaging vanadium and palladium cata

144 that increasing the number of deuterated bis-allylic carbons to include both C10 and C13 leads to a m

145 y abstracting hydrogen from one of three bis-allylic carbons within 1,4-cis,cis-diene units.

146 reactions of nonsilylated allenes involve an allylic cation intermediate by forming a C-O bond, at th

147 ently catalyzes its alkylation via either an allylic cation or a cationic transition state.

148 the reaction involves an argento-substituted allylic cation.

149 onors and each proceed via cationic species: allylic cations and oxocarbenium ions, respectively.

150 palladium(II) catalyst enables the efficient allylic CH oxidation of sterically hindered alpha-quater

151 r of the cyclobutene anion with considerable allylic character.

152 Allylic chlorides prepared from commercially available t

153 We show this allylic covalent inhibitor has different catalytic profi

154 An iron-catalyzed cyclization of hydroxy allylic derivatives into tetrahydropyrans possessing an

155 o-ene reaction of an allyl diazene, i.e., an allylic diazene rearrangement.

156 ctive transposition of the in situ generated allylic diazene.

157 talyze consecutive condensation reactions of allylic diphosphate acceptor with isopentenyl diphosphat

158 hesized by joining fragments for IPP and the allylic diphosphates with a C-C bond between the methyl

159 eogenic center with an aliphatic-substituted allylic electrophile is disclosed.

160 nantioselective allylation of trisubstituted allylic electrophiles has been developed.

161 anes from cycloalkanones, malononitrile, and allylic electrophiles, abundantly available reagent clas

162 Through modification of the leaving group of allylic electrophiles, we found that trisubstituted ally

163 onic pi-allyl Pd intermediates, derived from allylic ester carbonates and palladium(0) catalyst, were

164 nient asymmetric access to valuable branched allylic esters.

165 A borocyclopropanation of (E)- and (Z)-allylic ethers and styrene derivatives via the Simmons-S

166 or the isomerization of allylic alcohols and allylic ethers has been developed.

167 ion is also applicable for the first time to allylic ethers, yielding synthetically valuable enantioe

168 variety of substituted cinnamic and styrenyl allylic ethyl phosphates.

169 ly increased material throughput of valuable allylic fluoride products.

170 Allylic fluorides bearing a variety of functional groups

171 e enantioselective construction of secondary allylic fluorides bearing alpha-linear substituents.

172 aldehyde-selective Wacker-type oxidation of allylic fluorides proceeds with a nitrite catalyst.

173 o found that gamma-, beta-, homoallylic, and allylic fluorination are all possible and predictable th

174 yl group as well as a range of 2-substituted allylic fragments.

175 heteroatom stabilization of the intermediate allylic free radical two sites for oxidative product for

176 Allylic functionalization provides a direct path to chir

177 nal alkenes to be selectively converted into allylic functionalized products with high stereoselectiv

178 l that the azomethine ylide stabilized by an allylic group cycloadds to [60]fullerene in an efficient

179 inolenate substrates, abstraction of the bis-allylic H atoms competed with addition.

180 that selectively abstract allylic and/or bis-allylic H atoms.

181 of alkylzirconocene nucleophiles to racemic allylic halide electrophiles were conducted using a comb

182 ot observed, while introduction of a second, allylic heteroatom to the substrate results in diminishm

183 turation of aliphatic alcohols into valuable allylic, homoallylic, and bis-homoallylic alcohols has b

184 1,3-Enynes containing allylic hydrogens cis to the alkyne function as three-ca

185 The presence of allylic hydrogens cis to the less substituted alkene of

186 onates add to glycolaldehyde imine to afford allylic hydroxyl allenes, and allyl boronates add to alk

187 surface pocket and interactions between the allylic hydroxyl group and the BTN3A1 backbone.

188 Readily accessed allylic hydroxylamine esters undergo copper hydride-cata

189 complex, which undergoes imine addition with allylic inversion through a closed transition structure.

190 nce of a chiral copper catalyst, substituted allylic iodides couple with alpha-diazoesters to generat

191 of a 2,2'-dipyridyl ligand, diazoesters and allylic iodides react via a [2,3]-rearrangement pathway.

192 ze the addition of the hydrocarbon moiety of allylic isoprenoid diphosphates to the carbon-carbon dou

193 The electron-withdrawing nature of the allylic leaving group facilitates the addition by negati

194 ophilic attack on a Michael acceptor with an allylic leaving group.

195 imidazole, and pyrazole nucleophiles via an allylic linker under neutral conditions is disclosed.

196 ienic systems and of the stereocenter at C2 (allylic methine, alpha to the carboxy group) and the pro

197 ions that are able to directly functionalize allylic methyl, methylene and methine carbons in a catal

198 etric synthesis of alpha,alpha-disubstituted allylic N-arylamines based on a palladium-catalyzed ally

199 ows for the construction of optically active allylic nitriles and dithiolanes as well as branched alp

200 This allylic nucleophilic substitution works well with primar

201 Alkenes bearing quaternary carbons at the allylic or homoallylic position are readily oxidized to

202 tly, no scalable and sustainable solution to allylic oxidation exists.

203 Allylic oxidation of heteroatom substituted cyclic alken

204 oselective, regioselective and E/Z-selective allylic oxidation of unactivated internal alkenes via a

205 However, a general and selective allylic oxidation using the more common internal alkenes

206 ium dichromate (PDC)-mediated chemoselective allylic oxidation.

207 The successful strategy relied on late-stage allylic oxidations at two separate positions of the mole

208 Allylic oxidations have featured in hundreds of synthese

209 Unlike standard allylic oxidations, this oxidation is catalytic in chrom

210 divergent addition of substituted phenols to allylic oxides has been demonstrated using C2-symmetric

211 - and 1,4-addition of substituted phenols to allylic oxides is achieved by intercepting palladium pi-

212 ed allylic ammonium salt generation from the allylic phosphate and the glycine aryl ester.

213 lar hydroallylation of vinylarenes employing allylic phosphate electrophiles has been achieved throug

214 ve cyclizations of substrates containing a Z-allylic phosphate tethered to an alkyne are described.

215 the resulting alkenylnickel species onto the allylic phosphate.

216 ryl-substituted disubstituted alkenes within allylic phosphates and those with an alkyl or a silyl gr

217 electrophiles, we found that trisubstituted allylic phosphates are suitable electrophiles for asymme

218 developed reaction conditions where racemic allylic phosphates are suitable substrates using new pho

219 commercially available di-B(pin)-methane to allylic phosphates is introduced (pin=pinacolato).

220 ) (pin=pinacolato) and (E)-1,2-disubstituted allylic phosphates is introduced.

221 l-, alkenyl-, alkynyl- and alkyl-substituted allylic phosphates may thus be converted to the correspo

222 spectroscopy experiments on reactions using allylic phosphates showed the importance of allyl chlori

223 The reaction of allylic phosphates with enol silanes derived from dioxin

224 le N,N-disubstituted glycine aryl esters and allylic phosphates.

225 selective rhodium-catalyzed hydroboration of allylic phosphonates by pinacolborane affords chiral ter

226 from a single enantiomer of readily prepared allylic pivalate substrate.

227 rmediate formed by oxidative addition of the allylic pivalate to the Pd(0) complex.

228 m-catalyzed direct allylation of arenes with allylic pivalates in the presence of AgOPiv to afford th

229 ific, nickel-catalyzed Miyaura borylation of allylic pivalates, which delivers highly enantioenriched

230 er multiple bonds with a functional group in allylic position and some examples of successful transfo

231 n liquid ammonia, MCPs bearing a C-O bond at allylic position undergo both a reductive cleavage of th

232 lyunsaturated fatty acids (PUFAs) at the bis-allylic position; indeed, pretreating cells with PUFAs c

233 enium-catalyzed allylation of aldehydes with allylic pro-nucleophiles has been demonstrated to be an

234 The use of unsymmetrical allylic pro-nucleophiles was shown to give preferential

235 resonances associated with the olefinic and allylic protons as a result of them residing inside the

236 report, we describe the generation of remote allylic quaternary stereocenters beta, gamma, and delta

237 ol showed a lack of scrambling of a putative allylic radical at C-3 and C-4.

238 ither delta (Z or E depending on whether the allylic radical is cis or trans) or beta to the OH group

239 Due to the enhanced stability of the allylic radical, however, these peroxy radicals lose O2

240 rapid intramolecular H(*) transfer, yielding allylic radicals (LZZ + S(*) right arrow over left arrow

241 Oxygen (O2) adds to these allylic radicals either delta (Z or E depending on wheth

242 .03 (1sigma) to produce two sets of distinct allylic radicals.

243 erve as glycoside mimics that are capable of allylic rather than oxocarbenium cation stabilization.

244 rd reagent, and associated position-specific allylic rearrangement in diastereoselective Pictet-Speng

245 ueezing out the ligand from the conventional allylic S1 binding site, with proton abstraction being a

246 es and the reaction is also feasible with an allylic selenide.

247 r dienes containing both alkene pi-bonds and allylic sigma-bonds, and the ene yields are higher with

248 ergo reverse hydroboration reactions to form allylic silanes or can be oxidized to afford highly subs

249 The chiral allylic silanes prepared here undergo a variety of stere

250 able functionalized allylic systems, such as allylic silanes, boronates, germanes, stannanes, pivalat

251 as been developed to prepare enantioenriched allylic silanes.

252 GPP binds to an allylic site (S1) and aligns well with known S1 inhibito

253 diphosphate synthase (UPPS), and contains an allylic site (S1) in which DMAPP ionizes and a second si

254 unsaturated fatty acids (PUFAs) at their bis-allylic sites has been identified as a unique approach i

255 1,4-stereocontrol between the two respective allylic stereocenters.

256 cemic allylboronate reagent that contains an allylic stereogenic center, additions were exceptionally

257 d reduction of the hydrazone with an in situ allylic strain controlled retro-ene reaction of an allyl

258 lective allene formation that is governed by allylic strain.

259 er BF3.OEt2 catalysis or using alcohols with allylic substituents provides exclusively the correspond

260 l pincer carbodicarbene ligand that delivers allylic substituted arenes in up to 95% yield and up to

261 different NHC-Cu-catalyzed enantioselective allylic substitution (EAS) reactions further highlights

262 of the latter resulted in mono-arylation by allylic substitution and subsequent site-selective secon

263 ned Meyer-Schuster rearrangement/Tsuji-Trost allylic substitution clearly illustrates the enormous ad

264 udies of iridium-catalyzed, enantioselective allylic substitution enabled by (phosphoramidite,olefin)

265 The palladium-catalysed allylic substitution reaction is one of the most importa

266 Palladium-catalyzed allylic substitution reactions are among the most effici

267 The first instances of catalytic allylic substitution reactions involving a propargylic n

268 s because of the different mechanisms of the allylic substitution reactions.

269 cleophiles in Ir-catalyzed, enantioselective allylic substitution reactions.

270 rticular, a one-pot tandem alkyne silylation/allylic substitution sequence, in which both steps are c

271 Enantioselective allylic substitution with enolates derived from aliphati

272 ynthetic sequence involving enantioselective allylic substitution, cross-metathesis, dihydroxylation,

273 kinetically competent to be intermediates in allylic substitutions of branched, racemic allylic alcoh

274 are diastereoselective and enantioselective allylic substitutions with acyclic alpha-alkoxy ketones

275 We report stereodivergent allylic substitutions with aryl acetic acid esters catal

276 become widely established, the engagement of allylic substrates in C-C bond forming reactions has thu

277 Related bis-allylic substrates lead to amido 2-sulfinyl butadiene de

278 on, but prior cross couplings are limited to allylic substrates or deliver little to no enantiomeric

279 ough intramolecular radical aziridination of allylic sulfamoyl azides.

280 ropic rearrangement of allylic sulfoxides to allylic sulfenates is a reversible process, generally sh

281 ollowed by stereoselective preparation of an allylic sulfide by reaction of vinylzinc bromide with an

282 ery facilitates an ene-cycloisomerization of allylic-sulfide-containing alkenylidenecyclopropanes (AC

283 sigmatropic rearrangement reaction involving allylic sulfides and diazo reagents (Doyle-Kirmse reacti

284 r selectivity is obtained with both E- and Z-allylic sulfides and the reaction is also feasible with

285 (e.g., aryl-, benzyl-, and alkyl-substituted allylic sulfides) and alpha-diazo esters.

286 the highly enantioselective imidation of non-allylic sulfides.

287 venient Suzuki-Miyaura coupling of borylated allylic sulfones with various electrophiles in both inte

288 The [2,3]-sigmatropic rearrangement of allylic sulfoxides to allylic sulfenates is a reversible

289 bond formation of an amide-tethered benzylic/allylic system using DDQ under neutral conditions which

290 The oxidation of allylic systems has played a prominent role in this cont

291 , the direct arylation of non-functionalized allylic systems would enable access to a series of known

292 enables synthesis of valuable functionalized allylic systems, such as allylic silanes, boronates, ger

293 selective incorporation of fluoride ion into allylic systems.

294 hyde by a substitution reaction on a derived allylic tosylate.

295 Rapid access to allylic trichloroacetimidates bearing a 2-allylaminoaryl

296 A four-step synthesis of allylic trichloroacetimidates bearing a 2-proparyloxyary

297 The rearrangement of allylic trichloroacetimidates is a well-known transforma

298 oselective fluorination of racemic, branched allylic trichloroacetimidates with Et3N.3HF is a mild an

299 first kind (ultimately controlled by the 1,3-allylic-type strain) is central to this endeavor.

300 Despite the importance of allylic ylide rearrangements for the synthesis of comple