ライフサイエンスコーパス: alopecia areata

1 r are candidate genes in the pathogenesis of alopecia areata.

2 lium, are similar to those observed in human alopecia areata.

3 n our understanding of the genetic basis for alopecia areata.

4 rthritis, juvenile idiopathic arthritis, and alopecia areata.

5 irst-line agent for limited patchy childhood alopecia areata.

6 a novel high-incidence model for spontaneous alopecia areata.

7 ivilege as a key step in the pathogenesis of alopecia areata.

8 a contributing factor in the development of alopecia areata.

9 elogen effluvium, androgenetic alopecia, and alopecia areata.

10 gous genes potentially associated with human alopecia areata.

11 gs regarding the use of these treatments for alopecia areata.

12 C57BL/6J mice do not develop alopecia areata.

13 supporting this locus as being important in alopecia areata.

14 eles of the IL-1RN and various phenotypes of alopecia areata.

15 er of skin grafts from mice with spontaneous alopecia areata.

16 ral chronic inflammatory diseases, including alopecia areata.

17 ma, 0.03% for decubitus ulcer, and 0.01% for alopecia areata.

18 areata, whereas 39 of 44 controls developed alopecia areata.

19 ndrogenetic alopecia (37.3 128.4, 46.1]) and alopecia areata (24.9 [17.2, 32.6]) were statistically s

20 We aimed to determine the risk of alopecia areata (AA) and vitiligo associated with atopic

21 Treatments for alopecia areata (AA) have evolved over the decades from

22 However, vitiligo and alopecia areata (AA) have not been well characterized in

23 t has long been appreciated that episodes of alopecia areata (AA) have occurred after severely stress

24 Alopecia universalis is an uncommon form of alopecia areata (AA) involving hair loss over the entire

25 Alopecia areata (AA) is a common autoimmune disease resu

26 Alopecia areata (AA) is a common T cell-mediated disorde

27 Alopecia areata (AA) is a genetically determined, immune

28 Alopecia areata (AA) is a non-scarring inflammatory hair

29 Alopecia areata (AA) is among the most highly prevalent

30 Alopecia areata (AA) is an autoimmune disease of the hai

31 Alopecia areata (AA) is an autoimmune disease that attac

32 Alopecia areata (AA) is an autoimmune disease that targe

33 Alopecia areata (AA) is an autoimmune disorder of the ha

34 Alopecia areata (AA) is characterized by hair loss in pa

35 Characterizing blood profile of alopecia areata (AA) is important not only for treatment

36 Alopecia areata (AA) is one of the most common forms of

37 Alopecia areata (AA), a non-scarring inflammatory hair l

38 Alopecia areata (AA)-like hair loss in C3H/HeJ mice prov

39 ) is increased in patients with vitiligo and alopecia areata (AA).

40 eg) cells was reported to play a key role in alopecia areata (AA).

41 Alopecia areata affected and resistant mice were charact

42 Grafting alopecia areata affected C3H/HeJ mouse skin to littermat

43 In alopecia areata affected humans, 95 genes were significa

44 nic stimulus, but only lymph node cells from alopecia areata affected mice displayed an increased res

45 is results, lymph node and spleen cells from alopecia areata affected mice injected into normal haire

46 ion of CD4+ CD8+ expressing cells in chronic alopecia areata affected mice using monoclonal antibodie

47 Alopecia areata affected skin contained increased number

48 a is a cell-mediated autoimmune disease, but alopecia areata affected skin graft hosts may resist alo

49 Of 44 mice that received alopecia areata affected skin grafts but failed to devel

50 cia areata, only two of 22 receiving further alopecia areata affected skin grafts developed alopecia

51 utpatients clinic, 2 to 16 years of age with alopecia areata affecting at least 10% of scalp surface

52 Alopecia areata affects 1%-2% of the population and is h

53 For comparison, skin biopsies from alopecia areata and androgenetic alopecia affected human

54 ese therapeutic techniques for patients with alopecia areata and further refine which subtypes of the

55 heumatic disease, thyroid disease, vitiligo, alopecia areata and inflammatory bowel disease) were sel

56 be associated with Crohn disease, psoriasis, alopecia areata, and leprosy.

57 into catagen, such as androgenetic alopecia, alopecia areata, and telogen effluvium.

58 acne," "vitiligo," "seborrheic dermatitis," "alopecia areata," and "lichen planus." Diverse study pop

59 e relatives of 110 patients and 45 controls: alopecia areata, ankylosing spondylitis, dermatomyositis

60 mice expressing this TCR develop spontaneous alopecia areata at nearly 100% incidence.

61 ation was observed between IL-1RN and patchy alopecia areata but it was not statistically significant

62 ed C3H/HeJ mouse skin to littermates induces alopecia areata, but high dietary soy oil reduces alopec

63 In a rodent model, alopecia areata can be induced in normal haired C3H/HeJ

64 lated or downregulated during onset of mouse alopecia areata consistent with an inflammatory cell-med

65 eczema, psoriasis, acne vulgaris, pruritus, alopecia areata, decubitus ulcer, urticaria, scabies, fu

66 onse towards the graft, it is suggested that alopecia areata develops as a consequence of an inapprop

67 phenotype and functional status in extensive alopecia areata (EAA) scalp skin.

68 One patient with extensive alopecia areata experienced skin atrophy that resolved s

69 C3H/HeJ mice spontaneously develop alopecia areata from 5 mo of age and older in females an

70 Few treatments for alopecia areata have been well evaluated in randomized t

71 characterize a new high-incidence model for alopecia areata in C57BL/6J mice, the first to our knowl

72 , a gene that is known to be associated with alopecia areata in humans.

73 a(+)NKG2D(+) T effector memory cells mediate alopecia areata in part through Janus kinase (JAK) signa

74 These results suggest alopecia areata is a cell-mediated autoimmune disease, b

75 Alopecia areata is a suspected autoimmune hair loss dise

76 Alopecia areata is accompanied by Th2/Tc2 activation in

77 Alopecia areata is among the most prevalent autoimmune d

78 Alopecia areata is an autoimmune disease that targets ac

79 Alopecia areata is an idiopathic cause of hair loss with

80 Alopecia areata is an immune-mediated, nonscarring form

81 Alopecia areata is an inflammatory hair loss disease wit

82 or efficacy of currently used treatments for alopecia areata is lacking.

83 Alopecia areata is less common, but may be distressing,

84 Alopecia areata is one of the most frequent organ-restri

85 y loci have been implicated, the genetics of alopecia areata is still unclear.

86 ating question regarding the pathogenesis of alopecia areata is the potential linkage with the brain.

87 hrough Janus kinase (JAK) signaling and that alopecia areata might be treated with JAK inhibitors.

88 um (n = 30), androgenetic alopecia (n = 52), alopecia areata (n = 17), and alopecia areata totalis/un

89 Alopecia areata (n=138) and clinically normal (n=214) mi

90 In considering all patients with any form of alopecia areata, no association was found with IL-1RN.

91 In addition, although alopecia areata often results in significant psychologic

92 a affected skin grafts but failed to develop alopecia areata, only two of 22 receiving further alopec

93 Alopecia areata onset could be inhibited in skin-grafted

94 areata affected skin graft hosts may resist alopecia areata onset through active counter-regulatory

95 ainly to the contribution from mild cases of alopecia areata [OR 1.48 (0.96, 2.29)], suggesting that

96 sociation between IL1-RN*1 allele and patchy alopecia areata (p =0.045).

97 an immune cell-mediated disease mechanism in alopecia areata pathogenesis and suggested targeting ant

98 to normal haired littermates transferred the alopecia areata phenotype.

99 In this paper, we analyzed alopecia areata probands in a family-based sample (n = 1

100 to evaluate possible mechanisms involved in alopecia areata resistance.

101 Because alopecia areata resistant mice showed unimpaired respons

102 In contrast, alopecia areata resistant mouse skin did not display inc

103 CTLA4, CD44v variants, and FasL occurred in alopecia areata resistant mouse spleens.

104 1RN*2 allele was found to be associated with alopecia areata severity in a British case-control study

105 purported resistance locus) did not develop alopecia areata, supporting this locus as being importan

106 cia areata, but high dietary soy oil reduces alopecia areata susceptibility.

107 h telogen effluvium (50.1 [33.9, 66.33]) and alopecia areata totalis/universalis (52.3 [23.1, 81.5])

108 ecia (n = 52), alopecia areata (n = 17), and alopecia areata totalis/universalis (n = 7).

109 and reactive lymphocytes may be effective in alopecia areata treatment.

110 the case of dermatological diseases such as alopecia areata, vitiligo, psoriasis and atopic dermatit

111 o investigate the role of the IL-1 system in alopecia areata we examined three biallelic polymorphism

112 rticaria, pruritus, scabies, cellulitis, and alopecia areata were underrepresented in CDSR when match

113 mice, and mice with and without spontaneous alopecia areata, were similarly processed.

114 opecia areata affected skin grafts developed alopecia areata, whereas 39 of 44 controls developed alo

115 is characterized by loss of hair in patches (alopecia areata) with progression in some individuals to