ライフサイエンスコーパス: alpha(1) adrenergic receptor

1 other agents which are more specific for the alpha1 adrenergic receptor.

2 these modulatory effects are attributable to alpha1 adrenergic receptors.

3 mIPSCs frequency results from activation of alpha1 adrenergic receptors.

4 nformation describing this drug class at the alpha1-adrenergic receptors.

5 inity for dopamine D2, serotonin 5-HT1A, and alpha1-adrenergic receptors.

6 yl cyclase, and protein kinase A, as well as alpha1-adrenergic receptors.

7 E release and that this might be specific to alpha1-adrenergic receptors.

8 , thereby ruling out [3H]CUMI-101 binding to alpha1-adrenergic receptors.

9 PPG neurons, and this involved activation of alpha(1)-adrenergic receptors.

10 step in the agonist-dependent activation of alpha(1)-adrenergic receptors.

11 The binding affinities of 21 at alpha(1)-adrenergic receptors ([(3)H]prazosin, IC(50) =

12 These results demonstrate that alpha1 adrenergic receptors activate the transcription f

13 niform increase in cell dimension induced by alpha(1)-adrenergic receptor activation.

14 of cells with phenylephrine (PE), a specific alpha(1) adrenergic receptor agonist, increased protein

15 include insulin receptor substrate-1, as the alpha(1)-adrenergic receptor agonist also inhibited the

16 The selective alpha(1)-adrenergic receptor agonist methoxamine had no

17 The alpha(1)-adrenergic receptor agonist norepinephrine sele

18 with phorbol 12-myristate 13-acetate or the alpha(1)-adrenergic receptor agonist norepinephrine via

19 of the cells with phenylephrine, a specific alpha(1)-adrenergic receptor agonist, activated p70 S6 k

20 osolic free [Ca2+] oscillations evoked by an alpha1 adrenergic receptor agonist.

21 Consistent with this idea, the selective alpha1-adrenergic receptor agonist methoxamine was still

22 cked the induction of these responses by the alpha1-adrenergic receptor agonist phenylephrine, wherea

23 ith either insulin or phenylephrine (PE), an alpha1-adrenergic receptor agonist, induced Ser-9 phosph

24 itoneally) or saline, the response to the a) alpha1-adrenergic receptor agonist, phenylephrine; b) en

25 was perturbed by intravenous injection of an alpha1-adrenergic receptor agonist, unilateral pressure

26 was perturbed by intravenous injection of an alpha1-adrenergic receptor agonist, unilateral pressure

27 o phenylephrine (PE; 10(-10) to 10(-4)M), an alpha1-adrenergic receptor agonist, was examined.

28 sylated Rho and inhibited the characteristic alpha1-adrenergic receptor agonist-induced myofibrillar

29 alpha1-Adrenergic receptor agonist-induced myofibrilloge

30 rom the nucleus when cells were treated with alpha1-adrenergic receptor agonist.

31 are induced in cultured myocardial cells by alpha1- adrenergic receptor agonists, such as phenylephr

32 inately induced by growth promoters, such as alpha1-adrenergic receptor agonists (e.g. phenylephrine

33 In addition, Rlf potentiated alpha(1)-adrenergic receptor (alpha(1)-AR)-induced ANF e

34 Catecholamines and alpha(1)-adrenergic receptors (alpha(1)-ARs) cause cardi

35 use of TCA drugs increases the expression of alpha(1)-adrenergic receptors (alpha(1)-ARs).

36 The role of alpha(1)-adrenergic receptors (alpha(1)ARs) in cognition

37 alpha(1)-adrenergic receptors (alpha(1)ARs) regulate blo

38 alpha(1)-Adrenergic receptors (alpha(1A), alpha(1B), and

39 through vasopressin receptor (V1A-R) but not alpha1 adrenergic receptor (alpha1-AR), suggesting that

40 rat ventricular myocytes, stimulation of the alpha1-adrenergic receptor (alpha1-AdrR) activates a pro

41 oth muscle, or to phenylephrine, a selective alpha1-adrenergic receptor (alpha1-AR) agonist, was simi

42 An alpha1-adrenergic receptor (alpha1-AR) antagonist increa

43 alpha1ABKO) mice that lacked cardiac myocyte alpha1-adrenergic receptor (alpha1-AR) binding, aortic c

44 ing mediated by the angiotensin (Ang) II and alpha1-adrenergic receptor (alpha1-AR) pathways is impor

45 This study determined the effects of alpha1-adrenergic receptor (alpha1-AR) stimulation by ph

46 alpha1-Adrenergic receptor (alpha1-ARs) subtypes (alpha1

47 alpha1-Adrenergic receptors (alpha1-ARs) are members of

48 A growing body of evidence implicates alpha1-adrenergic receptors (alpha1ARs) as potent regula

49 The alpha1-adrenergic receptors (alpha1ARs) play an importan

50 loned cDNAs encoding three subtypes of human alpha1-adrenergic receptors (alpha1ARs), alpha1a, alpha1

51 litating dopamine (DA) neurotransmission via alpha1-adrenergic receptors (alpha1ARs).

52 alpha(1)-Adrenergic receptors also activate a PKCdelta-P

53 ffects of NE are mediated through Gq-coupled alpha(1)-adrenergic receptors and are mimicked by the ac

54 ility was assessed by measuring affinity for alpha(1)-adrenergic receptors and inhibition of neuronal

55 is proposed as a coupling mechanism between alpha(1)-adrenergic receptors and phospholipase C (PLC),

56 botropic neurotransmitter receptors (mGluRs, alpha1 adrenergic receptors, and muscarinic acetylcholin

57 ease of dopamine, activation of postsynaptic alpha1 adrenergic receptors, and suppression of InsP3-in

58 constrictions in MA but not in MV while the alpha(1)-adrenergic receptor antagonist, prazosin (0.1 m

59 Pretreatment with the alpha(1)-adrenergic receptor antagonist, prazosin, and t

60 The specific alpha(1)-adrenergic receptor antagonist, prazosin, inhib

61 us losartan (10 mg/kg b.wt) nor prazosin, an alpha1 adrenergic receptor antagonist, at doses of 5 mic

62 The alpha1-adrenergic receptor antagonist prazosin (0.1 micr

63 e Cl- current to 5.9 nM, and addition of the alpha1-adrenergic receptor antagonist prazosin did not c

64 up of innervated pigs during pharmacological alpha(1)-adrenergic receptor (AR) blockade, infarct size

65 ling pathways linking activation of specific alpha(1)-adrenergic receptor (AR) subtypes to these phys

66 ular, we show that although both mGluR5- and alpha(1)-adrenergic receptor (AR)-dependent LTDs involve

67 Activation of the endogenous alpha1-adrenergic receptor (AR) associated with human ao

68 61W retinal cells in high glucose and of the alpha1-adrenergic receptor (AR) on vascular lesions of t

69 alpha1-Adrenergic receptor (AR) subtypes in the heart ar

70 The three cloned alpha1-adrenergic receptor (AR) subtypes, alpha1B, alpha

71 hat the type 1 muscarinic receptor (m1R) and alpha1-adrenergic receptor (AR)-mediated SRF activation

72 alpha1 adrenergic receptors are known to activate protei

73 The alpha1-adrenergic receptors are targets for a number of

74 alpha(1)-Adrenergic receptors (ARs) are not well defined

75 alpha(1)-Adrenergic receptors (ARs) belong to the large

76 The role of alpha(1)-adrenergic receptors (ARs) in the regulation of

77 studies have demonstrated that activation of alpha(1)-adrenergic receptors (ARs) increased interleuki

78 its role in the cardioprotective actions of alpha(1)-adrenergic receptors (ARs) remains uncertain, b

79 alpha1-Adrenergic receptors (ARs) are well-known mediato

80 of blood pressure through interactions with alpha1-adrenergic receptors (ARs) in vascular smooth mus

81 direct evidence suggests that stimulation of alpha1-adrenergic receptors (ARs) increases smooth muscl

82 inhibited by OAG exposure or stimulation of alpha1-adrenergic receptors by phenylephrine.

83 Our results indicate that alpha(1)-adrenergic receptors can regulate both neurogen

84 We wondered if alpha1 adrenergic receptors could activate transcription

85 we show that in vivo respiratory LTF is also alpha1-adrenergic receptor dependent.

86 ral-midbrain dopaminergic neurons through an alpha1 adrenergic receptor-dependent mechanism within th

87 tes interfered with the basal expression and alpha1-adrenergic receptor-dependent activation of a TEF

88 ric nuclear-retained Vgl-4 protein inhibited alpha1-adrenergic receptor-dependent activation.

89 angiotensin II (Ang II) type 1 receptor and alpha1-adrenergic receptors has been described.

90 The understanding of the function of alpha(1)-adrenergic receptors in the brain has been limi

91 he mechanism underlying the critical role of alpha1 adrenergic receptors in the regulation of dopamin

92 ed if insulin or IGF-I induced expression of alpha1 adrenergic receptors in vascular smooth muscle ce

93 hat significantly altered mRNA levels of the alpha1- adrenergic receptor in the basal forebrain as we

94 our recently demonstrated mechanism whereby alpha1-adrenergic receptors in the same cell type regula

95 Activation of alpha1 adrenergic receptors increased cAMP accumulation

96 oss bovine RPE by activating apical membrane alpha(1)-adrenergic receptors, increasing [Ca2+](in), an

97 In addition, alpha1 adrenergic receptor-induced CREB phosphorylation

98 Activation of alpha(1)-adrenergic receptors influences both the contra

99 Control patients not taking any alpha1 adrenergic receptor inhibtors were also dilated w

100 Potency at alpha(1) adrenergic receptors is low for the four cinnam

101 Agonist-dependent activation of the alpha(1)-adrenergic receptor is postulated to be initiat

102 70 gene expression induced by stimulation of alpha1 adrenergic receptors is markedly attenuated, whic

103 concurrent episodic activation of 5-HT2 and alpha1-adrenergic receptors is necessary to produce long

104 emonstrated lead evolution from heterocyclic alpha(1)-adrenergic receptor ligands to highly dissimila

105 In applying this method to alpha(1)-adrenergic receptor ligands, we have demonstrat

106 alpha(1) Adrenergic receptors mediate both vascular and

107 examine the possible requirement for Rho in alpha1-adrenergic receptor-mediated hypertrophy.

108 Activation of alpha1 adrenergic receptors not only stimulates smooth m

109 ases neural stimulation of BAT and increases alpha1-adrenergic receptor number; however, the alpha1 r

110 PKC activity is implicated in the alpha(1)-adrenergic receptor pathway that activates PKD1

111 that in MDCK-D1 cells, epinephrine acting on alpha1-adrenergic receptors, promotes a rapid increase i

112 In addition, we show that stimulation of alpha(1)-adrenergic receptor-protein kinase D1-Rem1 sign

113 ikewise, ANP and 8-bromo-cGMP attenuated the alpha1-adrenergic receptor- stimulated increase in prepr

114 imulated increase in prepro-ANP mRNA and the alpha1-adrenergic receptor-stimulated decrease in sarcop

115 re, in myocytes, 8-bromo-cGMP attenuated the alpha1-adrenergic receptor-stimulated increases in c-fos

116 Activation of alpha1 adrenergic receptors stimulates mitogenesis in hu

117 Cardiac myocytes respond to alpha(1)-adrenergic receptor stimulation by a progressiv

118 alpha(1)-Adrenergic receptor stimulation increased the a

119 However, in adult normal neurospheres, alpha(1)-adrenergic receptor stimulation increased the e

120 ction caused by ischemic preconditioning and alpha(1)-adrenergic receptor stimulation.

121 the TGII mice at base line or in response to alpha(1)-adrenergic receptor stimulation; nor was protei

122 d signal transduction mechanisms involved in alpha1, adrenergic receptor stimulation of hsp7O gene ex

123 alpha1-Adrenergic receptor stimulation can inhibit the C

124 Alpha1-adrenergic receptor stimulation induces cardiac m

125 or (ANF) reporter gene expression induced by alpha1-adrenergic receptor stimulation with phenylephrin

126 neuronal progenitors colocalized with either alpha(1)-adrenergic receptor subtype in the olfactory bu

127 ing assays were used to examine the basis of alpha1-adrenergic receptor subtype selectivity for a ser

128 Epinephrine, acting through the alpha1-adrenergic receptor subtype, promoted transient t

129 cent protein or constitutively active mutant alpha(1)-adrenergic receptor subtypes in tissues in whic

130 ated from normal mice expressed a mixture of alpha(1)-adrenergic receptor subtypes, and stimulation o

131 n significantly reduced gene expression of 3 alpha(1)-adrenergic receptor subtypes, consistent with b

132 with that previously described for the other alpha1 adrenergic receptor subtypes, may shed light on t

133 nsfected with each of the three cloned human alpha1 adrenergic receptor subtypes, norepinephrine stro

134 y episodic but not continuous stimulation of alpha1-adrenergic receptors that requires protein kinase

135 slated and active in costimulating, with the alpha1-adrenergic receptor, the firing of DR 5-HT neuron

136 Noradrenaline activated alpha1-adrenergic receptors to increase GABA(A)-IPSC fre

137 was to determine the effect of endotoxin on alpha1-adrenergic receptor vasoconstriction and both end

138 tors, is also shown to be a modulator of the alpha1-adrenergic receptors, which suggests a general la

139 ncreases intracellular Ca(2+) similar to the alpha1 adrenergic receptor, while OAMB-K3 additionally s