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1 P=.01 for alkaline phosphatase, P<.0001 for alpha-fetoprotein).
2 (KO) tumors that express increased levels of alpha-fetoprotein.
3 ted by MELD score, HCC size, HCC number, and alpha-fetoprotein.
4 lar invasion, metastasis, serum albumin, and alpha-fetoprotein.
5 ed expression of fetal liver genes including alpha-fetoprotein.
6 d concomitantly with increased expression of alpha-fetoprotein.
7 yonic antigen, cytokeratin (CK) 7, CK20, and alpha-fetoprotein.
8 hepatocytes expressing the oncofetal marker, alpha-fetoprotein.
9 arly hepatic neoplasia and increase in serum alpha-fetoprotein.
10 respective of tumor burden or serum level of alpha-fetoprotein.
11 per cm increase [1.04-1.11]; p<0.0001), log alpha-fetoprotein (1.10 per unit increase [1.02-1.20]; p
12 Of patients with an elevated pretreatment alpha-fetoprotein, 85% were found to have declining alph
13 to the homogeneous liquid-phase detection of alpha-fetoprotein, a common tumor marker, the system sho
14 calization of beta-catenin and expression of alpha-fetoprotein, a prognostic marker of hepatocellular
15 alpha-fetoprotein (MSAFP) or amniotic fluid alpha-fetoprotein (AFAFP) levels or abnormalities visual
16 an 3 years, 3-7 years, and 8 years or older; alpha fetoprotein (AFP) concentration of 100 ng/mL or lo
17 aximal tumor diameter of 3 to 5 cm and serum alpha fetoprotein (AFP) greater than 100 ng/mL at transp
19 A technique serum levels of IL-6, IL-10, and alpha fetoprotein (AFP) were evaluated in all groups.
20 s carcinoembryonic antigen (CEA), bilirubin, alpha fetoprotein (AFP), and c-reactive protein (CRP) we
21 immunodominant and subdominant epitopes from alpha fetoprotein (AFP), restricted by HLA-A*0201, which
24 varian GCTs were resected and monitored with alpha-fetoprotein (AFP) ("watch-and-wait" approach).
27 motherapy levels of serum tumor markers were alpha-fetoprotein (AFP) 2.0 ng/mL, human chorionic gonad
28 FLEC were identified: cells expressing both alpha-fetoprotein (AFP) and albumin, but not CK-19; cell
31 of this study was to compare the accuracy of alpha-fetoprotein (AFP) and des-gamma-carboxy prothrombi
32 ts who had twice yearly screening with serum alpha-fetoprotein (AFP) and hepatic ultrasound than in p
33 he rate of decline of the serum tumor marker alpha-fetoprotein (AFP) and human chorionic gonadotrophi
34 her levels of alkaline phosphatase (ALP) and alpha-fetoprotein (AFP) and lower level of alanine amino
41 ter Transplant (RETREAT), which incorporates alpha-fetoprotein (AFP) at liver transplantation (LT), m
42 accurate quantitation of biomarkers such as alpha-fetoprotein (AFP) can be a key aspect of early sta
43 her the HCC-associated self/tumor antigen of alpha-fetoprotein (AFP) could be engineered to create an
44 7 HBsAg-positive Alaska native carriers with alpha-fetoprotein (AFP) determinations every 6 months.
46 pression under the control of an albumin and alpha-fetoprotein (AFP) enhancer and promoter (AFP-Notch
48 xamine the oval cell response and associated alpha-fetoprotein (AFP) gene expression by combining 2-A
49 ve shown that p53 represses hepatic-specific alpha-fetoprotein (AFP) gene expression by direct intera
58 analyzed methylation of the rat albumin and alpha-fetoprotein (AFP) genes by hydridizing labeled cDN
60 ng the neutrophil-lymphocyte ratio (NLR) and alpha-fetoprotein (AFP) have been associated with recurr
61 CK19 co-expressed with HepPar1, c-kit, and alpha-fetoprotein (AFP) in parenchymal cells in massive
62 formance status, Child-Pugh score (CPS), and alpha-fetoprotein (AFP) in predicting individual surviva
63 orted to be more sensitive and specific than Alpha-fetoprotein (AFP) in the diagnosis of HCC among th
72 for sensitive detection of cancer biomarker alpha-fetoprotein (AFP) is described that uses a graphen
77 noma (HCC), because the sensitivity of serum alpha-fetoprotein (AFP) is too low for this purpose.
80 ent cohort of 721 patients (542 men), median alpha-fetoprotein (AFP) level at the time of LT was 8.3
81 (BCLC) staging system, tumor size, and serum alpha-fetoprotein (AFP) level were investigated using Co
85 (ADI) in terms of toxicity, tumor response, alpha-fetoprotein (AFP) levels, and serum arginine level
87 yuridine (BrdU) labeling, liver DNA content, alpha-fetoprotein (AFP) mRNA production, and apoptosis a
88 s to identify a biomarker that could improve alpha-fetoprotein (AFP) performance in hepatocellular ca
90 Our group has shown that a rising natural alpha-fetoprotein (AFP) slope (NAS) correlates with tumo
96 To use the device under optimal conditions, alpha-fetoprotein (AFP) was detected at a limit of detec
99 the hepatitis B surface antigen (HBsAg) and alpha-fetoprotein (AFP) with the lowest concentration of
100 adhesion molecule (EpCAM)(+) HCC cells from alpha-fetoprotein (AFP)(+) tumors with cancer stem/proge
101 ls with activated Wnt signaling occupying an alpha-fetoprotein (AFP)+/cytokeratin-19 (CK-19)-positive
104 reased hepatic associated gene expression of alpha-fetoprotein (AFP), Albumin (Alb), Glucose-6-phosph
105 ltigene cluster that includes albumin (ALB), alpha-fetoprotein (AFP), and alpha-albumin/afamin (AFM).
107 , with some potential advantages compared to alpha-fetoprotein (AFP), but its role in the context of
108 biomarkers: carcinoembryonic antigen (CEA), alpha-fetoprotein (AFP), cancer antigen 125 (CA125), and
110 sed overlapping peptides spanning the entire alpha-fetoprotein (AFP), glypican-3 (GPC-3), melanoma-as
113 , a factor required for HSC homing, and also alpha-fetoprotein (AFP), indicating that they are fetal
114 ed hepatocellular carcinoma (HCC) biomarkers alpha-fetoprotein (Afp), insulin-like growth factor 2 (I
116 trongly associated with elevated circulating alpha-fetoprotein (AFP), low rate of necrosis/fibrosis a
118 10 mRNA expression was associated with serum alpha-fetoprotein (AFP), tumor-node-metastasis (TNM) sta
119 With this approach, an aptamer specific to alpha-fetoprotein (AFP), which is a biomarker for liver
120 ted polymer (MIP) for trace level sensing of alpha-fetoprotein (AFP), which is a well know cancer bio
121 sodium (MELD-Na), tumour burden score (TBS), alpha-fetoprotein (AFP), year of transplantation, underl
131 occurrence as well as patients with negative alpha-fetoprotein (AFP; n = 1), resulting in 24 patients
132 2 recently identified HCC subtypes (EpCAM(+) alpha-fetoprotein [AFP(+)] HCC and EpCAM(-) AFP(-) HCC).
134 of antibodies specific for epithelial cells (alpha-fetoprotein [AFP], albumin [ALB], pancytokeratin [
135 e Panel recommended measuring three markers (alpha-fetoprotein [AFP], human chorionic gonadotropin [h
137 f five (80%) patients with elevated markers (alpha-fetoprotein alone in three, alpha-fetoprotein and
138 erum alpha-fetoprotein and ferritin or serum alpha-fetoprotein alone, including four with coagulopath
139 albumin gene family is comprised of albumin, alpha-fetoprotein, alpha-albumin (afamin), and the more
140 encode the serum transport proteins albumin, alpha-fetoprotein, alpha-albumin, and vitamin D-binding
141 fibrinogen, fibronectin, transthyretin, and alpha-fetoprotein, an essential feature for functional H
142 l examination, measurement of tumor markers (alpha fetoprotein and human chorionic gonadotropin), and
143 te that this enhancer region is required for alpha-fetoprotein and albumin activation early in liver
144 lls were analyzed by immunocitochemistry for alpha-fetoprotein and albumin expression, qPCR for hepat
145 strate that RNA polymerase II loading on the alpha-fetoprotein and albumin promoters is reduced in th
148 f these genes, particularly that of albumin, alpha-fetoprotein and alpha-albumin, and their liver-spe
149 d markers (alpha-fetoprotein alone in three, alpha-fetoprotein and beta human chorionic gonadotropin
150 d higher than normal concentrations of serum alpha-fetoprotein and ferritin or serum alpha-fetoprotei
153 , 134-142 mEq/L [134-142 mmol/L]), and serum alpha-fetoprotein and human chorionic gonadotropin level
157 lutamyl transferase activity, elevated serum alpha-fetoprotein and undetectable liver bile salt expor
158 tients with slow serum tumor marker decline (alpha-fetoprotein and/or human chorionic gonadotrophin)
159 nti-carcinoembryonic antigen, CK7, CK20, and alpha-fetoprotein) and in the distinction from cholangio
160 nd-stage liver disease scores, pretransplant alpha fetoprotein, and cumulative tumor diameters; were
161 , secreted hepatic proteins such as Albumin, Alpha Fetoprotein, and Fibrinogen, metabolized ammonia,
165 tion expressed both donor marker (DPPIV) and alpha-fetoprotein, and some differentiated into hepatocy
166 total bilirubin, albumin, prothrombin time, alpha-fetoprotein, and tumor number, which were incorpor
167 tribution; levels of bilirubin, albumin, and alpha-fetoprotein; and WHO/EASL response rate predicted
168 tients with HBV had larger tumors and higher alpha-fetoprotein but less satellites and macrovascular
169 ibiting cytoplasmic/nuclear beta-catenin and alpha-fetoprotein but not CK19, HNF1beta, or Trop-2.
170 4, cytokeratin 19 (CK19), transthyretin, and alpha-fetoprotein by day 7, and expressed CK18, HNF-4, a
173 ed according to randomising centre and serum alpha-fetoprotein concentration (<400 ng/mL and >/=400 n
174 ction was assessed by expression of albumin, alpha-fetoprotein, cytochrome P4502E1, cytokeratin-18, t
176 re alpha-fetoprotein(+)/cytokeratin-19(+) or alpha-fetoprotein(+)/cytokeratin-19(-) and contain all o
178 d CaM kinase-like-1 (DCAMKL-1), Lgr5, CD133, alpha-fetoprotein, cytokeratin-19 (CK19), Lin28, and c-M
179 heral zones were simultaneously positive for alpha-fetoprotein, cytokeratin-19, and c-kit, indicating
180 lls express the classical oval cell markers (alpha-fetoprotein, cytokeratin-19, OV-1 antigen, a6 inte
182 ever, when the values of known serum markers alpha fetoprotein, des-gamma carboxyprothrombin, and GP7
187 nder the control of the albumin promoter and alpha-fetoprotein enhancer to ablate Jag1 in hepatoblast
188 he expression of vimentin, beta-III tubulin, alpha-fetoprotein, eomesodermin, HEB, ARNT, and FoxD3 as
190 oval cell proliferation and a lower level of alpha-fetoprotein expression as compared with control an
191 ogs induced albumin expression and decreased alpha-fetoprotein expression in HepG2 cells, which sugge
192 e basis of the similarities between Gpc3 and alpha-fetoprotein expression in the liver, we reasoned t
193 F-1 expression caused a dramatic decrease in alpha-fetoprotein expression, implying impaired oval cel
195 ok 2, spalt-like transcription factor 4, and alpha-fetoprotein expression; and high coordinated expre
199 the downstaging group included pretreatment alpha-fetoprotein >/=1,000 ng/mL (multivariate hazard ra
201 U/L) was present in all hepatitis patients, alpha-fetoprotein >10 ng/ml in 2/8 (25%), and cryoglobul
202 alyses identified age <65 years (P = 0.038), alpha-fetoprotein >200 ng/mL (P = 0.04), and vascular in
204 f embryonic stem (ES) cells expressing human alpha-fetoprotein (hAFP) under control of the endogenous
205 ize of tumors, presence of metastases, serum alpha-Fetoprotein, hepatitis serologies, severity of hep
207 ted clinical diagnostic application, such as alpha-fetoprotein in liver carcinoma, and kallikreins 6
208 evaluate the prognostic usefulness of serum alpha-fetoprotein in patients with well-compensated cirr
209 cificity of des-gamma-carboxyprothrombin and alpha-fetoprotein in the diagnosis of hepatocellular car
210 ted on a clinically relevant assay to detect alpha-fetoprotein, in which a 42-fold enhancement to sen
211 The proposed Time-Radiological-response-Alpha-fetoprotein-INflammation (TRAIN) score was the bes
212 (AST)/alanine aminotransferase (ALT) ratio, alpha-fetoprotein, insulin, and homeostatic model assess
215 zard ratio, 1.61; 95% CI: 1.3-2.1) and serum alpha-fetoprotein level >/=455 ng/mL (hazard ratio, 2.15
216 Patients with larger (3-5 cm) tumors, serum alpha-fetoprotein level >/=455 ng/mL, or a MELD score >/
218 a cirrhotic liver in the presence of a serum alpha-fetoprotein level >400 ng/mL also is diagnostic.
220 s showed significant effects of pretreatment alpha-fetoprotein level (P = .03) and ADC ratio (P < .00
221 rnational normalized ratio greater than 1.1, alpha-fetoprotein level greater than 20 ng/mL, multiple
223 priate candidates for liver transplantation; alpha-fetoprotein level limitations should be incorporat
224 mal range, 13-60 U/L [0.21-1.0 mukat/L]), an alpha-fetoprotein level of 3.81 ng/ mL (normal range, 0-
225 ory studies were significant for an elevated alpha-fetoprotein level of 7051 ng/ml and mild anemia.
226 vascular invasion, extrahepatic disease, and alpha-fetoprotein level to best supportive care plus ora
228 was achieved in 10 patients (83.3%), and the alpha-fetoprotein level was also decreased to normal in
230 erum markers for ovarian cancer were normal (alpha-fetoprotein level, 1.6 microg/L; Ca-125 level, 15
231 clinical factors (age, gender, preoperative alpha-fetoprotein level, hepatitis serology, number of t
232 oenvironment also correlated with high serum alpha-fetoprotein levels (P < 0.001), macrovascular inva
233 -Pugh scores (P = .003), higher pretreatment alpha-fetoprotein levels (P = .04), and a greater number
235 tion between second-trimester maternal serum alpha-fetoprotein levels and the risk of SIDS, which may
236 Patients were followed with CT scan and alpha-fetoprotein levels every 3 months for 2 years post
237 etoprotein, 85% were found to have declining alpha-fetoprotein levels from a pretreatment mean of 140
238 ence, 2.7 per 10,000 births among women with alpha-fetoprotein levels in the lowest quintile and 7.5
239 and increased aspartate aminotransferase and alpha-fetoprotein levels were associated with HCC (p < 0
240 otransferase/alanine aminotransferase ratio, alpha-fetoprotein levels, and IL28B single-nucleotide po
241 talian Program components, Child-Pugh class, alpha-fetoprotein levels, and percentage of tumor replac
242 markers of tumor aggressiveness (high serum alpha-fetoprotein levels, P = 0.038; satellite nodules,
253 ariables (Model for End-Stage Liver Disease, alpha-fetoprotein, Milan-Criteria status, and radiologic
254 logical response to loco-regional therapies, alpha-fetoprotein modification, inflammatory markers, an
255 eal patients, and follow-up, including serum alpha-fetoprotein monitoring for early detection of mali
256 d time from primary resection to recurrence, alpha-fetoprotein more than 100 ng/mL at recurrence, rec
257 ellite nodules, albumin less than 3.5 gm/dL, alpha-fetoprotein more than 100 ng/mL, and any vascular
259 FGF19 transgenic mice had elevated hepatic alpha-fetoprotein mRNA as early as 2 months of age, and
260 er RNA (mRNA) levels and reduced Albumin and Alpha-fetoprotein mRNA levels, indicating that they are
261 eatures were greatly elevated maternal serum alpha-fetoprotein (MSAFP) or amniotic fluid alpha-fetopr
263 ype (albumin-positive, transferrin-positive, alpha-fetoprotein-negative) and are able to proliferate
264 n of neuronal cellular adhesion molecule and alpha-fetoprotein, neuroectodermal, and endodermal marke
266 inal nonseminoma (group A) and elevations of alpha-fetoprotein of 100 ng/mL or greater or of human ch
268 essable patients with elevated CSF levels of alpha-fetoprotein or betahuman chorionic gonadotropin ha
269 ction of either one liver cancer marker, the alpha-fetoprotein, or the detection of Hepatitis C Virus
271 almitic acid, suggesting that the high serum alpha-fetoprotein phenotype of G1, associated with the k
273 striking increase in the number of c-kit and alpha-fetoprotein-positive progenitors, without altering
276 under age 40; p < 0.001), with greater serum alpha-Fetoprotein production (median level: HBV-1000 ng/
277 s simultaneously stimulated both albumin and alpha-fetoprotein promoters with minimal competition, bu
278 in activation early in liver development and alpha-fetoprotein reactivation during liver regeneration
282 f the albumin gene family that we have named Alpha-fetoprotein Related Gene (ARG) since it exhibits g
284 accessing the brain, therefore, to overcome alpha-fetoprotein sequestration of E2, estrogen replacem
289 m known genes present in fetal liver include alpha-fetoprotein, stem cell factor, erythroid alpha-spe
290 apid loss of expression of the tumour marker alpha-fetoprotein, the increase in expression of liver c
292 rimester quadruple screening (measurement of alpha-fetoprotein, total human chorionic gonadotropin, u
293 erm has recently been shown to interact with alpha-fetoprotein transcription factor and repress chole
294 cPR included a favorable post-LRT radiologic/alpha fetoprotein tumor response, longer time interval f
296 ity of California at San Francisco criteria, alpha-fetoprotein, up-to-7 criteria, TTV, and platelet c
298 An 8-mer peptide (EMTOVNOG) derived from alpha-fetoprotein was compared with tamoxifen for activi
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