ライフサイエンスコーパス: alpha-glucosidase

1 the glycogen-degrading lysosomal enzyme acid-alpha glucosidase.

2 lic mechanism-based covalent inhibitor of an alpha-glucosidase.

3 s an NAD(+)- and metal ion-dependent phospho-alpha-glucosidase.

4 colonies on this medium due to production of alpha-glucosidase.

5 by a deficiency of the lysosomal enzyme acid alpha-glucosidase.

6 at pH 4.3, classifying the enzyme as an acid alpha-glucosidase.

7 ed the genes encoding the neopullulanase and alpha-glucosidase.

8 g inhibitor of glucoamylase, isomaltase, and alpha-glucosidase.

9 when coincubated with the recombinant human alpha-glucosidase.

10 crog/ml) displayed strong inhibition towards alpha-glucosidase.

11 also potent inhibitors of alpha-amylase and alpha-glucosidase.

12 ong natural inhibitors for alpha-amylase and alpha-glucosidase.

13 nt to the extensive digestion by the mucosal alpha-glucosidases.

14 e roles of individual and collective mucosal alpha-glucosidases.

15 identical, functions with other cloned human alpha-glucosidases.

16 J-based iminosugar derivatives to inhibit ER alpha-glucosidases.

17 does not inhibit endoplasmic reticulum (ER) alpha-glucosidases.

18 mmalian and yeast origin than to other plant alpha-glucosidases.

19 inhibitor of the endoplasmic reticulum (ER) alpha-glucosidases.

20 f altered glycosylation after treatment with alpha-glucosidase-1 inhibitor, N-butyldeoxynojirimycin (

21 Anthocyanin-rich extracts inhibited alpha-glucosidase (37.8%), alpha-amylase (35.6%), dipept

22 scle disorder caused by a deficiency of acid alpha-glucosidase, a glycogen-degrading lysosomal enzyme

23 The alpha-glucosidase, a member of GH31 family, shows substr

24 gainst enzymes with biological significance (alpha-glucosidase, acetylcholinesterase and butyrylcholi

25 his study was to investigate how the mucosal alpha-glucosidases act with alpha-amylase to digest gran

26 g a combination of alpha-amylase and mucosal alpha-glucosidase activities, were applied to three gran

27 and inhibitory effects on alpha-amylase and alpha-glucosidase activities.

28 by evaluating the lipase, alpha-amylase and alpha-glucosidase activities.

29 d with fluctuations in lysosomal and neutral alpha-glucosidase activities.

30 6pc(-/-) mice, pharmacological inhibition of alpha-glucosidase activity almost completely abolished r

31 ome monoterpenes inhibited alpha-amylase and alpha-glucosidase activity and stimulated glucose uptake

32 se-related changes in glycogen, glucose, and alpha-glucosidase activity are also found in spinal cord

33 A genotype does not affect the regulation of alpha-glucosidase activity by repressing sugars.

34 Additionally, alpha-glucosidase activity could be measured in extracts

35 The acidic alpha-glucosidase activity from broccoli flower buds was

36 es per cell) more than doubled the amount of alpha-glucosidase activity in cell extracts.

37 d sugars, and it completely eliminated CR of alpha-glucosidase activity in liquid medium.

38 Extracts with IC50 for alpha-glucosidase activity in the 0.010-0.079mgmL(-1) ra

39 rich extracts from certain berries inhibited alpha-glucosidase activity in vitro.

40 a-D-glucopyranoside revealed that the acidic alpha-glucosidase activity is predominantly located in t

41 le blood-based assay to measure the level of alpha-glucosidase activity is the optimal initial test f

42 No residual alpha-glucosidase activity was detectable in extracts fr

43 n-regulated in the expression of MAL1, total alpha-glucosidase activity was not decreased in leaves a

44 However, alpha-glucosidase activity was only partially relieved f

45 steps and the potential ability to modulate alpha-glucosidase activity were tested.

46 We show that alpha-glucosidase activity, i.e. glycogen debranching an

47 he function of a potato gene (MAL1) encoding alpha-glucosidase activity, transgenic plants in which M

48 sorghum and rye extracts inhibited (p<0.05) alpha-glucosidase activity, whereas barley and sorghum e

49 in an unidentified gene(s) that up-regulates alpha-glucosidase activity.

50 e activities of the three lysosomal enzymes (alpha-glucosidase (AG), beta-galactosidase (B-GAL) and b

51 an NAD(+) and metal ion-dependent 6-phospho-alpha-glucosidase (AglB).

52 a single primer (M13 core) and assessed for alpha-glucosidase (alpha-Glu) activity.

53 nd phytoprostanes (PhytoPs) on four enzymes: alpha-glucosidase, alpha-amylase, acetylcholinesterase,

54 ssociated with metabolic syndrome, including alpha-glucosidase, amylase and lipase and exhibited anti

55 hysiological relevance of acid maltase (acid alpha-glucosidase, an enzyme that degrades lysosomal gly

56 nds and the inhibitory effect of extracts on alpha-glucosidase and alpha-amylase activities were inve

57 olyphenols from guarana were able to inhibit alpha-glucosidase and alpha-amylase activities.

58 For this purpose, alpha-glucosidase and alpha-amylase assays were assessed

59 of Verdolino extracts exhibited the highest alpha-glucosidase and alpha-amylase inhibitory activity

60 strong antioxidant activities, inhibition of alpha-glucosidase and alpha-amylase, inhibition of angio

61 Western blot analysis using anti-alpha-glucosidase and anti-beta-glycosidase antibodies i

62 Phospho-alpha-glucosidase and EIIA are encoded by genes at the L

63 pe patients, restoring normal levels of acid alpha-glucosidase and glycogen.

64 lipase and comparable and lower activity on alpha-glucosidase and hyaluronidase, respectively.

65 wed the highest inhibition of alpha-amylase, alpha-glucosidase and lipase (IC50: 0.38mg/mL, 0.87mug/m

66 ced LDL-cholesterol peroxidation, as well as alpha-glucosidase and lipase activities were demonstrate

67 power as well as evaluation of inhibition of alpha-glucosidase and lipase activities.

68 syndrome-associated enzymes (alpha-amylase, alpha-glucosidase and lipase) was evaluated.

69 d region is 43% identical to human lysosomal alpha-glucosidase and other glycosyl hydrolases.

70 the deficiency of the lysosomal enzyme acid alpha-glucosidase and results in cellular lysosomal and

71 Phospho-alpha-glucosidase and sucrose-6-phosphate hydrolase exhi

72 samples inhibited the enzymes alpha-amylase, alpha-glucosidase and xanthine oxidase.

73 lustat (Zavesca)] based on the inhibition of alpha-glucosidases and glucosyltransferases.

74 sults for hSGLT3 are compared with those for alpha-glucosidases and human SGLT type 1 (hSGLT1), a wel

75 arch is unexpectedly associated with mucosal alpha-glucosidases and not just alpha-amylase.

76 ng-alkyl-chain DNJ derivatives to inhibit ER alpha-glucosidases and their antiviral effect, ruling ou

77 The neopullulanase and alpha-glucosidase appeared to be the main enzymes involv

78 with sequence similarity to human lysosomal alpha-glucosidase as a probe, a potato cDNA was isolated

79 . meliloti possesses at least one additional alpha-glucosidase as well as a lower-affinity transport

80 oscopy, i.e., HPLC-SPE-ttNMR/high-resolution alpha-glucosidase assay.

81 d sharply later in germination, as an 81 kDa alpha-glucosidase became prominent.

82 act showed promising results as inhibitor of alpha-glucosidase, being almost 9 times more effective t

83 ompounds toward five different glycosidases, alpha-glucosidase, beta-glucosidase, isomaltase, alpha-m

84 High-resolution alpha-glucosidase biochromatograms of these extracts all

85 ing characteristics are similar to those for alpha-glucosidases, but there are no interactions with h

86 gh the toggling of activities of the mucosal alpha-glucosidases by selective enzyme inhibition.

87 loned human alpha-glucosidase (human neutral alpha-glucosidase C or GANC) is a previously uncharacter

88 Thus, mucosal alpha-glucosidases can have a synergistic effect with al

89 Phospho-alpha-glucosidase catalyzed the hydrolysis of a wide var

90 eolysis of intact viral capsid proteins, the alpha-glucosidase-catalyzed hydrolysis of p-nitrophenyl-

91 Mutations in alpha-glucosidase cause accumulation of glycogen in lyso

92 An alpha-glucosidase cDNA clone derived from barley aleuron

93 plasmid containing a 5'-shortened human acid alpha-glucosidase cDNA driven by the cytomegalovirus pro

94 A putative alpha-glucosidase clone has been isolated from a cDNA li

95 ase (PD) is a metabolic myopathy due to acid alpha-glucosidase deficiency and characterized by extens

96 ical cloning of two alleles of human neutral alpha-glucosidase (designated GANC on the human gene map

97 PR-mediated uptake of recombinant human acid-alpha-glucosidase during ERT in mice with Pompe disease

98 dies detected 101 and 95 kDa forms of barley alpha-glucosidase early in seed germination.

99 6-Phospho-alpha-glucosidase (EC 3.2.1.122) from B. subtilis cross-

100 S. sanguis IUOM-11M alpha-glucosidase (EC 3.2.1.20) demonstrated a pH optimu

101 his was accompanied by a 14-fold increase in alpha-glucosidase enzyme activity.

102 uorogenic substrate is a useful tool for the alpha-glucosidase enzyme assay and will facilitate compo

103 eveloped a new fluorogenic substrate for the alpha-glucosidase enzyme assay, resorufin alpha-d-glucop

104 racts showed more than 80% inhibition of the alpha-glucosidase enzyme at a concentration of 40mg/mL (

105 e is the least studied of the membrane-bound alpha- glucosidase enzymes.

106 The 6-phospho-alpha-glucosidase expressed in E. coli (like the enzyme

107 The recombinant alpha-glucosidase expressed in E. coli was used to gener

108 UV-4B is an iminosugar that inhibits the alpha-glucosidase family of enzymes and subsequently the

109 he unique and shared roles of the individual alpha-glucosidases for alpha-glucans persisting after st

110 s the most potent (IC50: 0.25mug/mL) against alpha-glucosidase; Fraction IV from black turtle bean wa

111 nment with its homologs, the novel 6-phospho-alpha-glucosidase from B. subtilis can be assigned to th

112 sly, a neopullulanase, a pullulanase, and an alpha-glucosidase from B. thetaiotaomicron had been puri

113 found to be low micromolar inhibitors of the alpha-glucosidase from baker's yeast with Ki's near to 2

114 H and its homologs revealed that the phospho-alpha-glucosidase from F. mortiferum belongs to the seve

115 h polyclonal rabbit antibody against phospho-alpha-glucosidase from Fusobacterium mortiferum.

116 and the enzymatic activity of a recombinant alpha-glucosidase from human gut bacterium Ruminococcus

117 utation in the active site of the homologous alpha-glucosidase from Sulfolobus solfataricus resulted

118 ly, we also found that, unlike mammals, acid alpha-glucosidase from zebrafish and medaka does not app

119 the glycogen-degrading lysosomal enzyme acid alpha -glucosidase (GAA) (also called "acid maltase"), c

120 bolic disorder characterized by lack of acid-alpha glucosidase (GAA) resulting in ubiquitous lysosoma

121 f lysosomal glycogen-hydrolyzing enzyme acid alpha-glucosidase (GAA) activity, which results in lysos

122 Acid alpha-glucosidase (GAA) cleaves the alpha1-4 and alpha1-

123 Enzyme or gene replacement therapy with acid alpha-glucosidase (GAA) has achieved only partial effica

124 sported to and degraded in lysosomes by acid alpha-glucosidase (GAA) in mammals, but it is unclear wh

125 Acid alpha-glucosidase (GAA) is a lysosomal enzyme that degra

126 Acid alpha-glucosidase (GAA) is a lysosomal enzyme that hydro

127 of a modified Ad vector encoding human acid alpha-glucosidase (GAA) resulted in efficient hepatic tr

128 erated by treating the lysosomal enzyme acid alpha-glucosidase (GAA) with recombinant GlcNAc-phosphot

129 e II (GSDII), caused by a deficiency in acid alpha-glucosidase (GAA), leads to lysosomal accumulation

130 cardiomyopathy caused by deficiency of acid alpha-glucosidase (GAA), skeletal muscle seems an obviou

131 system to improve lysosomal delivery of acid alpha-glucosidase (GAA), the enzyme deficient in patient

132 s directly related to the deficiency of acid alpha-glucosidase (GAA), which degrades glycogen in the

133 esisted enzyme replacement therapy with acid alpha-glucosidase (GAA), which has been attributed to in

134 rior muscles of young-, mid-, and late-stage alpha-glucosidase (GAA)-deficient mice.

135 d by deficiency of the lysosomal enzyme acid alpha-glucosidase (GAA).

136 by a deficiency of the lysosomal enzyme acid alpha-glucosidase (GAA).

137 , mice homozygous for disruption of the acid alpha-glucosidase gene (6(neo)/6(neo)) lack enzyme activ

138 The phospho-alpha-glucosidase gene (aglB) lies adjacent to a second

139 The genome contains a single form of this alpha-glucosidase gene and two additional sequences that

140 expression and regulation of the human acid alpha-glucosidase gene as well as other lysosomal enzyme

141 previously demonstrated that the human acid alpha-glucosidase gene expression is regulated by a sile

142 This is the first report of an alpha-glucosidase gene from the archaeal domain.

143 steady-state expression level of the potato alpha-glucosidase gene was low in most tissues examined,

144 Disruption of the alpha-glucosidase gene, susB, reduced the rate of growth

145 Arabidopsis contains at least three alpha-glucosidase genes; Aglu-1 and Aglu-3 are sequenced

146 -center structure with that of the 6-phospho-alpha-glucosidase GlvA from Bacillus subtilis reveals a

147 es indicate that the closest S. solfataricus alpha-glucosidase homologs are of mammalian origin.

148 e hypothesized that an as-yet uncloned human alpha-glucosidase (human neutral alpha-glucosidase C or

149 Processing alpha-glucosidase I (GluI) is a key member of the eukary

150 pha-glucosidase I may have a small amount of alpha-glucosidase I activity in vivo based on the low le

151 Chinese hamster ovary cells are defective in alpha-glucosidase I activity, which removes the distal a

152 tro assays of each enzyme gave no detectable alpha-glucosidase I activity.

153 ereas the S440F mutation largely inactivates alpha-glucosidase I both in vitro and in vivo.

154 charide glucosidase (OsMOGS), an ortholog of alpha-glucosidase I in Arabidopsis, which trims the term

155 When expressed in the presence of the alpha-glucosidase I inhibitor N-butyldeoxynojirimycin an

156 However, the S440F alpha-glucosidase I may have a small amount of alpha-glu

157 of knf embryos demonstrated that KNF encodes alpha-glucosidase I, the enzyme that catalyzes the first

158 bsorbance capacity and effectively inhibited alpha-glucosidase (IC(50): 0.83 mg/ml) and pancreatic li

159 chickpea showed inhibitory activity against alpha-glucosidase (IC50 6967 +/- 343 and 2885 +/- 85.4 m

160 mug/ml (bran) and 148.23 mug/ml (hulls)] and alpha-glucosidase [IC50, 62.1 mug/ml (bran) and 68.14 mu

161 ystal structures of the main ERQC enzyme, ER alpha-glucosidase II (alpha-GluII; from mouse), alone an

162 more similar to the glycoprotein-processing alpha-glucosidase II of mammalian and yeast origin than

163 dicate a unique role for the S. solfataricus alpha-glucosidase in carbohydrate metabolism.

164 n markedly enhanced expression of human acid-alpha-glucosidase in nonhuman primates.

165 to phosphorylate a lysosomal hydrolase, acid alpha-glucosidase in vitro.

166 alpha-Amylase combined with the mucosal alpha-glucosidases in the intestinal extract showed high

167 d pancreatic alpha-amylases and four mucosal alpha-glucosidases, including N- and C-terminal subunits

168 vefold range of dietary NSP intake, although alpha-glucosidase increased on a resistant starch-enrich

169 N-terminal sequence from the 96-kD broccoli alpha-glucosidase indicated that it corresponds to the A

170 iated uptake because alpha-l-iduronidase and alpha-glucosidase induced tolerance with the drug regime

171 However, no alpha-glucosidase inhibition activity was observed under

172 alpha-Glucosidase inhibition activity, cell viability an

173 m of this study was to evaluate the in vitro alpha-glucosidase inhibition and antioxidant activity of

174 m of this study was to evaluate the in vitro alpha-glucosidase inhibition and antioxidant activity of

175 In in vitro alpha-glucosidase inhibition and antioxidant activity, t

176 es and their antiviral effect, ruling out ER alpha-glucosidase inhibition as the sole mechanism respo

177 alytical platform based on a high-resolution alpha-glucosidase inhibition assay in combination with h

178 multivariate data analysis, high-resolution alpha-glucosidase inhibition assays and HPLC-HRMS-SPE-NM

179 anol extract of H. biflora (HBMe) showed 50% alpha-glucosidase inhibition at the concentration of 480

180 rthermore investigated using high-resolution alpha-glucosidase inhibition profiling combined with hig

181 30-50% alpha-glucosidase inhibition was observed in ultrasound,

182 Therefore, the combination of alpha-glucosidase inhibition with its antiradical capaci

183 fits (anticancer activity, alpha-amylase and alpha-glucosidase inhibition, angiotensin-converting-enz

184 a significant potential to use as a natural alpha-glucosidase inhibition, antioxidant agent.

185 e used for pinpointing HPLC peaks displaying alpha-glucosidase inhibition.

186 Water fraction (WF) of ME was a stronger alpha-glucosidase inhibitor (EC50 2.9 mug/mL) than querc

187 itor (SMD, 0.33 [95% CI, 0.13 to 0.52]), and alpha-glucosidase inhibitor (SMD, 0.35 [95% CI, 0.12 to

188 The effect of the alpha-glucosidase inhibitor acarbose on cardiovascular o

189 of glycan processing in CHO cells using the alpha-glucosidase inhibitor N-butyl-deoxynojirimycin, we

190 Using castanospermine (an alpha-glucosidase inhibitor) and yeast strains defective

191 oselective synthesis of nectrisine, a potent alpha-glucosidase inhibitor, was carried out starting fr

192 WF was a competitive alpha-glucosidase inhibitor.

193 s the increased amount of quercetin, a known alpha-glucosidase inhibitor.

194 therapeutic target for type II diabetes, and alpha-glucosidase inhibitors have been used in the clini

195 Nateglinide and alpha-glucosidase inhibitors may have slightly weaker ef

196 Alpha-glucosidase inhibitors play a potential role in th

197 antioselective total synthesis of the potent alpha-glucosidase inhibitors schulzeine A, B, and C and

198 Previous studies have suggested that alpha-glucosidase inhibitors such as castanospermine and

199 these phenolic sub-classes were more potent alpha-glucosidase inhibitors than the clinical drug, aca

200 7-2.08 kg), glucagon-like peptide-1 analogs, alpha-glucosidase inhibitors, and dipeptidyl peptidase-4

201 , more expensive agents (thiazolidinediones, alpha-glucosidase inhibitors, and meglitinides), older a

202 by structural identification targeted these alpha-glucosidase inhibitors, as demonstrated by a proof

203 sulins, sulfonylureas, glinides, biguanides, alpha-glucosidase inhibitors, thiazolidinediones, glucag

204 n efficient method for the identification of alpha-glucosidase inhibitors.

205 izidines revealed to be potent and selective alpha-glucosidase inhibitors.

206 a natural source of potent antioxidants and alpha-glucosidase inhibitors.

207 The alpha-glucosidase inhibitory activities of the VJ and FV

208 C50 values following fermentation, while the alpha-glucosidase inhibitory activities ranged from 95.2

209 isolates were evaluated for antioxidant and alpha-glucosidase inhibitory activities.

210 E. maxima were evaluated for antiradical and alpha-glucosidase inhibitory activities.

211 ion of X2C gave a subfraction, with enhanced alpha-glucosidase inhibitory activity (IC50=6.15mug/mL),

212 HR-bioassay/HPLC-HRMS-SPE-NMR showed the alpha-glucosidase inhibitory activity of A. nodosum, F.

213 The antioxidant capacity and the alpha-glucosidase inhibitory activity of the duodenal ex

214 ebaudioside-A showed concentration-dependent alpha-glucosidase inhibitory activity with IC50=35.01 mu

215 d fast identification of three analytes with alpha-glucosidase inhibitory activity, and subsequent HP

216 Samples showing more than 60% alpha-glucosidase inhibitory activity, at a concentratio

217 y (DPPH), polyphenol content (GAE) and yeast alpha-glucosidase inhibitory activity.

218 cies were screened for their antioxidant and alpha-glucosidase inhibitory activity.

219 atform enables fast screening for individual alpha-glucosidase inhibitory analytes in complex matrice

220 e extracts of seaweeds for alpha-amylase and alpha-glucosidase inhibitory effects.

221 strated stronger antioxidant activity and an alpha-glucosidase inhibitory property than positive cont

222 le and lemon myrtle fractions had pronounced alpha-glucosidase-inhibitory activities (IC(50): 0.30 an

223 In addition, alpha-glucosidase is a therapeutic target for type II di

224 ently demonstrated that the metabolic enzyme alpha-glucosidase is under CR in L. monocytogenes.

225 Inhibition of alpha-amylase and/or alpha-glucosidases is a strategy for treatment of type 2

226 tivity of a second glucose-repressed enzyme, alpha-glucosidase, is 10-fold higher in NCTC 7973 than i

227 a6/Delta6), like the recently published acid alpha-glucosidase knockout with disruption of exon 13, h

228 influences glucose generation at the mucosal alpha-glucosidase level.

229 l-NBDNJ is able to enhance lysosomal alpha-glucosidase levels in Pompe disease fibroblasts, e

230 metabolic syndrome, including alpha-amylase, alpha-glucosidase, lipase and hydroxyl methyl glutaryl C

231 The specific activities of three enzymes, an alpha-glucosidase (malA), a beta-glycosidase (lacS), and

232 s of three glycosyl hydrolases, including an alpha-glucosidase (malA), a beta-glycosidase (lacS), and

233 nolic compounds did not affect inhibition of alpha-glucosidase (maltase) activity, which remained rel

234 tural gene (malA) encoding the major soluble alpha-glucosidase (maltase) and flanking sequences from

235 in turn hydrolyzed to glucose by the mucosal alpha-glucosidases, maltase-glucoamylase (MGAM) and sucr

236 ium mortiferum malH gene, encoding 6-phospho-alpha-glucosidase (maltose 6-phosphate hydrolase; EC 3.2

237 not efficiently secreted from cells in which alpha-glucosidase mediated N-glycan trimming is inhibite

238 ith flaviviruses (for example, V-ATPases and alpha-glucosidases), most of the DVHFs were newly implic

239 nated malR, which regulates expression of an alpha-glucosidase not controlled by SusR.

240 Apoplastic alpha-glucosidases occur widely in plants but their func

241 se-6'-phosphate hydrolase (MalH) and phospho-alpha-glucosidase (PagL), respectively.

242 capacities and inhibitory activities against alpha-glucosidase, pancreatic lipase and angiotensin I-c

243 extract and its inhibiting activity against alpha-glucosidase, pancreatic lipase and hyaluronidase w

244 Only the mucosal alpha-glucosidases provide the final hydrolytic activiti

245 CCR of maltose-inducible alpha-glucosidase, raffinose-inducible alpha-galactosida

246 ose 6-phosphate hydrolase) and pagl (phospho-alpha-glucosidase), respectively, reside in separate ope

247 atively high doses of recombinant human acid alpha-glucosidase (rhGAA) may be required to reduce the

248 idase, and the 1-nonylazetidine 25 inhibited alpha-glucosidase (Saccharomyces cerevisiae) with an IC(

249 All four alpha-glucosidases share digestion of linear regions of

250 via their ability to inhibit alpha-amylase, alpha-glucosidase, sodium-glucose transporters, and panc

251 The IC(50) values show that the four alpha-glucosidase subunits could be differentially inhib

252 as located upstream of the gene encoding the alpha-glucosidase (susB).

253 system now exists for recombinant human acid alpha-glucosidase targeted to heart and capable of corre

254 wed superior inhibition of alpha-amylase and alpha-glucosidase than foxtail millet cultivars.

255 se (SI) is an intestinal membrane-associated alpha-glucosidase that breaks down di- and oligosacchari

256 lB is an unusual NAD+/Mn2+-dependent phospho-alpha-glucosidase that promotes growth of MG-1655 (pAP1)

257 , Mn2+, and dithiothreitol-dependent phospho-alpha-glucosidases that can be assigned to family 4 of t

258 copyranosyl:phosphoglucohydrolase (6-phospho-alpha-glucosidase) that requires both NAD(H) and divalen

259 Acid alpha-glucosidase, the product of a housekeeping gene, i

260 beginning with alpha-amylase and followed by alpha-glucosidase to produce glucose.

261 te, a cell line producing high levels of the alpha-glucosidase was established.

262 o GID of the samples, only the inhibition of alpha-glucosidase was preserved.

263 Enzymatically active, recombinant alpha-glucosidase was synthesized and secreted from the

264 ular starch by mammalian recombinant mucosal alpha-glucosidases was observed which shows that these e

265 ibitory properties against alpha-amylase and alpha-glucosidase were investigated.

266 nd lysosomal acid maltase, two major hepatic alpha-glucosidases, were unaltered in L-G6pc(-/-) mice,

267 ese residues were not acquired on human acid alpha-glucosidase when expressed in zebrafish embryos, s

268 y measuring its activation by an ER resident alpha-glucosidase, which is dependent on entry into the

269 system, and one (aglA) appears to encode an alpha-glucosidase with homology to family 13 of glycosyl

270 from black currant and rowanberry, inhibited alpha-glucosidase with IC(50) values respectively of 20

271 nnaeus were found to be potent inhibitors of alpha-glucosidase with IC50 values of 0.32 and 0.49 mug/

272 s were found to be potent inhibitors of rice alpha-glucosidase with K(i) and IC(50) values in the nan

273 ysosomal enzymes alpha-l-iduronidase or acid alpha-glucosidase with the receptor-associated protein w

274 two commercial samples were able to inhibit alpha-glucosidase, with EC(50) values lower than that fo

275 Fractions X1C and X2C notably inhibited alpha-glucosidase, with IC50=9.89 and 8.05mug/mL, respec