ライフサイエンスコーパス: alpha-linolenic acid

1 in essential fatty acids (alpha-linoleic and alpha-linolenic acids).

2 nfidence interval, 0.42 to 0.88) for dietary alpha-linolenic acid.

3 eic acid and by increasing the proportion of alpha-linolenic acid.

4 y-18:2Delta(9,15)) in cultures supplied with alpha-linolenic acid.

5 ts products, all of which are metabolites of alpha-linolenic acid.

6 Major fatty acids were linoleic acid and alpha-linolenic acid.

7 cid linoleic acid and the omega-3 fatty acid alpha-linolenic acid.

8 atty acids (EFA), arachidonic, linoleic, and alpha-linolenic acids.

9 tial fatty acids, arachidonic, linoleic, and alpha-linolenic acids.

10 dical-catalyzed nonenzymatic peroxidation of alpha-linolenic acid (1).

11 vealed high levels of linoleic acid (4.72%), alpha-linolenic acid (10.8%) and phytols (12.0%), as wel

12 Higher intake levels of alpha-linolenic acid (18:3 n-3) were correlated with low

13 nent exception being a relative reduction in alpha-linolenic acid (18:3(cisDelta9,12,15)) in both the

14 fatty acids (PUFAs) linoleic acid (18:2) and alpha-linolenic acid (18:3) in triacylglycerols (TAG) ar

15 entified the major chloroplast galactolipid: alpha-linolenic acid (18:3)-7Z,10Z,13Z-hexadecatrienoic

16 ry was noticed in the concentration level of alpha-linolenic acid (18:3, ALA), arachidonic acid (20:4

17 t the n-3 fatty acids, the concentrations of alpha-linolenic acid (18:3n-3) and docosahexaenoic acid

18 n laboratory animals and humans suggest that alpha-linolenic acid (18:3n-3) may reduce the risk of ar

19 h the levels for linoleic acid (18:2n-6) and alpha-linolenic acid (18:3n-3) remained unaltered, there

20 From these studies it appeared that alpha-linolenic acid (18:3n-3) was equivalent to n-6-ric

21 This process leads to selective losses of alpha-linolenic acid (18:3n-3).

22 [U-(13)C]-alpha-Linolenic acid (18:3n-3, ALA) was thermally oxidiz

23 Because alpha-linolenic acid (18:3n-3; ALA) is the direct precur

24 ns of plasma linoleic acid (18:2n-6; LA) and alpha-linolenic acid (18:3n-3; ALA).

25 erythrocytes, r(s)=0.24; plasma, r(s)=0.25), alpha-linolenic acid (18:3n-3; erythrocytes, r(s)=0.18;

26 CO is high in alpha-linolenic acid (18:3omega3, ALA) (30%), with an om

27 lect dietary intake (linoleic acid, 18:2n-6; alpha-linolenic acid, 18:3n-3; eicosapentaenoic acid, 20

28 c acid, 6 of 8 dogs were protected, and with alpha-linolenic acid, 6 of 8 dogs were also protected (P

29 soluble dietary fibres (74%), ash (51%), and alpha-linolenic acid (67.4%).

30 by the diet or endogenous biosynthesis from alpha-linolenic acid, accretes during the perinatal brai

31 s to determine whether vegetable oil-derived alpha-linolenic acid added to a diet enriched in n-6 fat

32 d by (13)C nuclear magnetic resonance (NMR), alpha-linolenic acid (ALA) and docosapentaenoic acid (DP

33 tituents such as gamma-linolenic acid (GLA), alpha-linolenic acid (ALA) and stearidonic acid (SA), as

34 d the association between the n-3 fatty acid alpha-linolenic acid (ALA) and the incidence of congesti

35 revious studies indicated that the intake of alpha-linolenic acid (ALA) can alter the concentration o

36 d diets containing 3.5% or 5.3% of energy as alpha-linolenic acid (ALA) for two consecutive 14-wk per

37 ll and concentrations of total n-3 PUFAs and alpha-linolenic acid (ALA) in erythrocytes, which were o

38 (P < 0.000001), whereas the availability of alpha-linolenic acid (ALA) increased from 0.39% to 0.72%

39 ncrement: 0.99; 95% CI: 0.88, 1.10], whereas alpha-linolenic acid (ALA) intake was inversely associat

40 alpha-Linolenic acid (ALA) is an n-3 (omega-3) fatty aci

41 alpha-Linolenic acid (ALA) is associated with a low risk

42 A large proportion of dietary alpha-linolenic acid (ALA) is oxidized, and because of l

43 hway and consequently modifies the effect of alpha-linolenic acid (ALA) on myocardial infarction (MI)

44 he control group (n = 12) received either 8% alpha-linolenic acid (ALA) or 0.6% DHA, both of which su

45 Metabolites of the alpha-linolenic acid (ALA) pathway, known to exist in pl

46 ication of four minor geometrical isomers of alpha-linolenic acid (ALA) present in linseed oil sample

47 reviously we reported that dietary intake of alpha-linolenic acid (ALA) reduces atherogenesis and inh

48 We previously reported that a diet high in alpha-linolenic acid (ALA) reduces lipid and inflammator

49 tudy is to develop vegetable oil blends with alpha-linolenic acid (ALA) rich Garden cress oil (GCO) a

50 mportance of the conversion of plant-derived alpha-linolenic acid (ALA) to EPA and DHA is debated.

51 nversion of the plant-derived n-3 fatty acid alpha-linolenic acid (ALA) to EPA and DHA is very low, n

52 Desaturation of dietary alpha-linolenic acid (ALA) to omega-3 (n-3) long-chain f

53 In a multivariable model, plasma alpha-linolenic acid (ALA) was associated with a lower r

54 n EPIC-InterAct, among long-chain n-3 PUFAs, alpha-linolenic acid (ALA) was inversely associated with

55 ng relative risks (95% CIs) for phospholipid alpha-linolenic acid (ALA) were 1.0 (reference), 0.93 (0

56 nolenic acid (GLA), and Delta(9,12,15) 18:3, alpha-linolenic acid (ALA)).

57 ega-3 FA) source, containing 1.63 g/100mL of alpha-linolenic acid (ALA), 0.73 g/100 mL of stearidonic

58 The relation between alpha-linolenic acid (ALA), a plant-derived omega-3 (n-3

59 Prior studies of alpha-linolenic acid (ALA), a plant-derived omega-3 (n-3

60 ntagineum (EO), or rapeseed oil (RO) rich in alpha-linolenic acid (ALA), but a poor source of LC-PUFA

61 about the association between adipose tissue alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA),

62 ave been made for n-3 fatty acids, including alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA),

63 Linoleic acid (LA), alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA),

64 with regard to any differential influence of alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA),

65 r vitamin B-12, retinol, linoleic acid (LA), alpha-linolenic acid (ALA), or ratios of betaine to chol

66 arachidonic acid to the omega3 fatty acids, alpha-linolenic acid (ALA), stearidonic acid, eicosatetr

67 s of the metabolic syndrome, but the role of alpha-linolenic acid (ALA), the metabolic precursor of E

68 oth LCPUFA and their precursor omega-3 PUFA, alpha-linolenic acid (ALA), whereas terrestrial insects

69 essential omega-3 polyunsaturated fatty acid alpha-linolenic acid (ALA).

70 biosynthesized from n-3 FAs such as 18:3n-3 [alpha-linolenic acid (ALA)] or 20:5n-3 [eicosapentaenoic

71 f the plant-derived omega-3 (n-3) fatty acid alpha-linolenic acid (ALA, 18:3; n-3) may reduce coronar

72 (Linum usitatissimum L.) has high amounts of alpha-linolenic acid (ALA; 18:3(cis)(Delta9,12,15)) and

73 oximately 0.7% of energy), of which 1.4 g is alpha-linolenic acid (ALA; 18:3) and 0.1-0.2 g is eicosa

74 alpha-Linolenic acid (ALA; 18:3n-3) has been associated

75 ounsaturated fatty acid; MUFA), MUFA + 3.5 g alpha-linolenic acid (ALA; MUFA + ALA) from high-ALA can

76 8:2 conjugated linoleic (CLA-1.4 times), and alpha-linolenic acids (ALA-1.6 times), as compared to co

77 Plants provide alpha-linolenic acid [ALA; 18:3n-3 (18:3omega-3)], which

78 s identified as an independent confounder of alpha-linolenic acid (an omega-3PUFA; p = 0.0210).

79 Alpha-linolenic acid, an intermediate-chain n-3 fatty ac

80 etween the ratio of dietary linoleic acid to alpha-linolenic acid and BMD at the hip in 642 men, 564

81 also reported an inverse association between alpha-linolenic acid and cardiovascular disease morbidit

82 omega-3 polyunsaturated fatty acids such as alpha-linolenic acid and docosahexaenoic acid (DHA) are

83 The omega-3 PUFAs alpha-linolenic acid and docosahexaenoic acid (DHA) inje

84 lipins from arachidonic acid, linoleic acid, alpha-linolenic acid and docosahexaenoic acid PUFAs are

85 act of P. chrysogenum afforded the compounds alpha-linolenic acid and ergosterol endoperoxide, which

86 protoporphyrin IX-reconstituted muCOX-2 with alpha-linolenic acid and G533V muCOX-2 with AA indicate

87 deficient in the essential fatty acids (EFA) alpha-linolenic acid and linoleic acid are consumed.

88 being impacted and altered in EAE, including alpha-linolenic acid and linoleic acid metabolism (PUFA)

89 ry measures to increase and decrease intakes alpha-linolenic acid and linoleic acid, respectively, to

90 Diet-tissue correlation coefficients for alpha-linolenic acid and linoleic acid, respectively, we

91 The relationship between alpha-linolenic acid and myocardial infarction was nonli

92 n-3 alpha-linolenic acid and n-6 cis-linoleic acid were not

93 The inverse association observed between alpha-linolenic acid and nonfatal acute MI suggests that

94 mined the association between adipose tissue alpha-linolenic acid and nonfatal acute myocardial infar

95 ne the association between dietary intake of alpha-linolenic acid and risk of fatal ischemic heart di

96 The specificity of the association between alpha-linolenic acid and SCD supports the hypothesis tha

97 Low level of palmitic, stearic and alpha-linolenic acid and very high level of linoleic aci

98 ntaenoic acid, and docosahexaenoic acid] and alpha-linolenic acid) and n-6 PUFAs (linoleic acid and a

99 y, chia seed flour, which is rich in omega-3 alpha-linolenic acid, and common and tartary buckwheat f

100 bsolute amounts of dietary linoleic acid and alpha-linolenic acid are of relevance to the efficiency

101 ed the association between dietary intake of alpha-linolenic acid assessed via updated food-frequency

102 Greater alpha-linolenic acid (assessed either in adipose or by q

103 yed similar signaling properties to the LCFA alpha-linolenic acid at human FFA4 across various assay

104 ) (beta = -0.21, P = 0.060) and plant-based (alpha-linolenic acid) (beta = -0.33, P = 0.024) fatty ac

105 urthermore, docosahexaenoic acid (C22:6n-3), alpha-linolenic acid (C18:3n-3), conjugated linoleic aci

106 is specific for linoleic acid (C18:2n-6) and alpha-linolenic acid (C18:3n-3).

107 tty acid in some vegetable oils, cis-9,12,15-alpha-linolenic acid (C18:3omega-3), administered intrav

108 yoghurt and low-fat milk always possessed an alpha-linolenic acid (C18:3omega3) content above the min

109 from 29.94 +/- 1.14% to 36.85 +/- 1.13% and alpha-linolenic acid concentrations increased from 0.78

110 s that consumption of vegetable oils rich in alpha-linolenic acid confers important protection agains

111 roscopy data, stable-isotope data (IRMS) and alpha-linolenic acid content (gas chromatography) was us

112 of milk protein and milk fat as well as the alpha-linolenic acid content of these samples were deter

113 alpha-Linolenic acid could be a viable cardioprotective

114 Consumption of vegetable oils rich in alpha-linolenic acid could confer important cardiovascul

115 acid (EPA) and docosahexaenoic acid, but not alpha-linolenic acid, decrease on a double-logarithmic s

116 The precursor n-3 PUFA alpha-linolenic acid does not appear to exert antiinflam

117 The diets were enriched in alpha-linolenic acid, eicosapentaenoic (EPA) and docosah

118 nity for the polyunsaturated n-3 fatty acids alpha-linolenic acid, eicosapentaenoic acid, docosahexae

119 lementation of Chlorella gave rise to mainly alpha-linolenic acid enrichment.

120 fused in situ with arterial blood containing alpha-linolenic acid, EPA, or docosahexaenoic acids.

121 Oleic, linoleic and alpha-linolenic acid excretion were also significantly h

122 FGL1 was sufficient to release linoleic and alpha-linolenic acids from wheat spike tissue.

123 jects in the top quintiles of adipose tissue alpha-linolenic acid had a lower risk of MI than those i

124 s was disrupted in the tocopherol-deficient, alpha-linolenic acid-hypersensitive Synechocystis mutant

125 (95% confidence interval, 0.25 to 0.67) for alpha-linolenic acid in adipose tissue and 0.61 (95% con

126 alpha-Linolenic acid in adipose tissue ranged from 0.36%

127 The proportion of alpha-linolenic acid in CEs (P < 0.001 for group x time

128 ulted in a 90% increase in the proportion of alpha-linolenic acid in root lipids.

129 resulted in seed-specific enhanced level of alpha-linolenic acid in sesame.

130 supplements and also formed by conversion of alpha-linolenic acid in soy and rapeseed (canola) oils,

131 ions of some FAs but lower concentrations of alpha-linolenic acid in their subcutaneous adipose tissu

132 was accompanied by a continuous increase of alpha-linolenic acid in total lipids, whereas no such ac

133 ies to be more effective than its precursor, alpha-linolenic acid, in enriching membranes with eicosa

134 tricular arrhythmia, it is not known whether alpha-linolenic acid influences ventricular repolarizati

135 ompared with women in the lowest quintile of alpha-linolenic acid intake, those in the highest 2 quin

136 mega-3 fatty acids and plant omega-3 such as alpha-linolenic acid is associated with lower risk of my

137 The intake of alpha-linolenic acid is estimated to be approximately 1-

138 The apparent protective effect of alpha-linolenic acid is most evident among subjects with

139 ports the hypothesis that a higher intake of alpha-linolenic acid is protective against fatal IHD.

140 alpha-linolenic acid is the most abundant fatty acid com

141 nction with a high ratio of linoleic acid to alpha-linolenic acid, it would be prudent to recommend d

142 AP knockout A. thaliana plants show elevated alpha-linolenic acid levels and marked reproductive defe

143 Highest conjugated fatty acids, alpha-linolenic acid, linoleic acid, saturated fatty aci

144 (EPA) may be biosynthesized from a precursor alpha-linolenic acid (LNA) or obtained preformed in the

145 Alpha-linolenic acid may protect against cardiovascular

146 ta suggest that increasing dietary intake of alpha-linolenic acid may reduce the risk of SCD but not

147 that provide polyunsaturated fats, including alpha-linolenic acid, may reduce the risk of fatal IHD.

148 n of wild-type sensitivity against exogenous alpha-linolenic acid of the otherwise resistant Deltafat

149 e available for evaluation of the effects of alpha-linolenic acid on serum lipid concentrations.

150 ntaenoic acid and docosahexaenoic acid or as alpha-linolenic acid) on cardiovascular disease outcomes

151 id and docosahexaenoic acid) and plant oils (alpha-linolenic acid) on human serum lipids and lipoprot

152 Here we show that the addition of alpha-linolenic acid or EPA to arterial blood inhibits t

153 Flaxseed oil is a rich source of 18:3n-3 (alpha-linolenic acid, or ALA), which is ultimately conve

154 0(palmitic acid),22:6n-3(DHA) PC > di18:3n-3(alpha-linolenic acid) PC > di22:6n-3PC with a range in p

155 rived from the enthalpy curves reflected the alpha-linolenic acid proportion in the oils.

156 rom fish or fish-oil supplements, but not of alpha-linolenic acid, reduces the rates of all-cause mor

157 d omega-3 (omega3) fatty acids (linoleic and alpha-linolenic acid, respectively) in the cytochrome P4

158 Consumption of both alpha-linolenic acid (RR, 0.73; 95% CI, 0.59-0.89; P = .

159 igh-oleic acid soybean oil (HiOleic-SO), low-alpha-linolenic acid soybean oil (LoALA-SO), or partiall

160 The fad3-2 mutant with impaired alpha-linolenic acid synthesis developed significantly s

161 presented a significantly higher content of alpha-linolenic acid than P. volubilis (51.3 and 45.6 g/

162 the essential fatty acids linoleic acid and alpha-linolenic acid to arachidonic acid and DHA, respec

163 relevance to the efficiency of conversion of alpha-linolenic acid to eicosapentaenoic acid and docosa

164 The previously recognized capability of alpha-linolenic acid to stimulate the generation of adip

165 ignificantly increased the concentrations of alpha-linolenic acid, total polyunsaturated fatty acids

166 PUFA dihomo-gamma-linolenic acid; gamma- and alpha-linolenic acids, two popular dietary PUFAs, were l

167 LA uptake and [3H]thymidine incorporation by alpha-linolenic acid was 0.18 and 0.25 mM, respectively.

168 acid and other nutrients, a higher intake of alpha-linolenic acid was associated with a lower relativ

169 Dietary intake of alpha-linolenic acid was associated with an increased ri

170 alpha-Linolenic acid was associated with moderately incr

171 The intake of alpha-linolenic acid was derived from a 116-item food-fr

172 In comparison, plant-derived alpha-linolenic acid was inversely associated with morta

173 ng long-chain n-3 fatty acids, the intake of alpha-linolenic acid was inversely associated with the r

174 cosahexaenoic acid + docosapentaenoic acid + alpha-linolenic acid) was associated with lower ventricu

175 Use of mustard oil, which is rich in alpha-linolenic acid, was associated with a lower risk t

176 negar salad dressing, an important source of alpha-linolenic acid, was associated with reduced risk o

177 Dietary omega-3 fatty acids (eg, alpha-linolenic acid) were inhibitory at concentrations

178 ted fatty acids (rich in oleic, linoleic and alpha-linolenic acids) were supplemented to dairy ewes a

179 om polyunsaturated fatty acids (linoleic and alpha-linolenic acid), whereas for "Vatikiotiko" saturat

180 were highly resistant to externally provided alpha-linolenic acid, whereas wild-type cells bleached u

181 site and is highly active with linoleic and alpha-linolenic acids (which occur naturally in Anabaena

182 turated free fatty acids (FFAs) linoleic and alpha-linolenic acid, which we detected in F. graminearu

183 also observed when adding the JA precursor, alpha-linolenic acid with SA.

184 acid, docohexaenoic acid, linoleic acid, and alpha-linolenic acid, with incident CVD and all-cause mo