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1 that anti-SG1 IgG prevents ligand binding by alpha4beta1 integrin.
2 X9, but not GST, and binding was mediated by alpha4beta1 integrin.
3 ntial activities to inhibit human and murine alpha4beta1 integrin.
4 spreading and stress fiber formation through alpha4beta1 integrin.
5 with lamin B1 during T-cell adhesion through alpha4beta1 integrin.
6 (LFA-1) is known to induce cross-talk to the alpha4beta1 integrin.
7 role in modulating the adhesive function of alpha4beta1 integrin.
8 g trafficking receptors and instead required alpha4beta1-integrin.
9 hesiveness, due in part to the activation of alpha4beta1 integrins.
10 xpress alpha(v)beta5, beta2, alpha2beta1, or alpha4beta1 integrins.
11 g pathway also suppressed sVCAM-1 binding to alpha4beta1 integrins.
13 ce triggers actin polymerization at upstream alpha4beta1 integrin adhesion sites and the adjacent cor
14 ent on B-Raf activity or expression, whereas alpha4beta1 integrin affinity for soluble VCAM-1 was not
15 that the gene encoding the alpha4 subunit of alpha4beta1 integrin (alpha4beta1) is essential for this
16 es directed against the alpha-subunit of the alpha4beta1 integrin and against intracellular cell adhe
17 d by the presence of extradomain A activates alpha4beta1 integrin and augments osteoblast differentia
18 ly selective and functional link between the alpha4beta1 integrin and IL-3/IL-3-receptor that could a
19 These effects were shown to be specific for alpha4beta1 integrin and not other integrins, such as al
20 equence in blade B4 (P3 sequence) that bound alpha4beta1 integrin and partially impaired cell adhesio
21 expression was coordinately regulated by the alpha4beta1 integrin and the innate immune receptor toll
22 cell-stromal cell interactions mediated via alpha4beta1 integrin and vascular cell adhesion molecule
23 co-signaling pathway between alpha5beta1 and alpha4beta1 integrins and are independent of heparan sul
24 mily, supports leukocyte adhesion by binding alpha4beta1 integrins and is critical for the recruitmen
25 n antagonistic, role between alpha5beta1 and alpha4beta1 integrins and suggests that interactions bet
26 ndent manner via very late antigen-4 (VLA-4; alpha4beta1 integrins) and VLA-5 (alpha5beta1 integrins)
27 by alphavbeta3, alphavbeta5, alpha5beta1, or alpha4beta1 integrin, and antagonists for the integrins
28 hocyte function-associated antigen (LFA)-1], alpha4beta1 integrin, and cadherin-11 in the development
29 T cells depended on the activation state of alpha4beta1 integrin, and TSP1 inhibited interaction of
31 adhesion molecule-1 (VCAM-1) and its ligand, alpha4beta1 integrin, are key mediators of leukocyte rec
32 is not related to surface expression of the alpha4beta1 integrin, as demonstrated by flow cytometry.
33 and stress fiber formation were mediated by alpha4beta1 integrin because soluble anti-alpha4 integri
35 ragment of fibronectin, which contains three alpha4beta1-integrin binding sites, or the H0 fragment,
42 eukotriene B4 signaling and induction of the alpha4beta1 integrin cell adhesion complex in hematopoie
43 t interactions between the Hep II domain and alpha4beta1 integrin could modulate the strength of cyto
45 marked defect in alphavbeta3/alphavbeta5 and alpha4beta1 integrin-directed migration measured on vitr
46 emonstrate that T-cell adhesion to VCAM1 via alpha4beta1 integrin drives histone H3 methylation (H3K9
47 at two such molecules, E-selectin ligand and alpha4beta1 integrin, enable activated and memory T cell
50 Activated T cells use very late antigen-4/alpha4beta1 integrin for capture, rolling on, and firm a
51 tion of 50% = 2 pM) that binds the activated alpha4beta1 integrin found on a variety of malignant lym
55 s migration of fibroblast-like cells lacking alpha4beta1 integrin, in which Rac1 and myosin II modula
56 c lung fibroblasts, we show that ligation of alpha4beta1 integrin induces a significant increase in p
58 B3B4, we have identified B3B4 as the primary alpha4beta1 integrin-interacting region within PEX9.
62 novel aspect of the function of fibronectin-alpha4beta1 integrin interactions that holds significanc
65 nt-1 (CS-1) peptide therapy, which blocks FN-alpha4beta1 integrin leukocyte interactions, in a well-e
66 nan but had no effect on adhesion to VCAM-1 (alpha4beta1 integrin ligand), confirming its specific in
67 1) as a model LDV-containing ligand to study alpha4beta1 integrin-ligand interactions on Jurkat cells
68 reduces T cell resistance to shear stress to alpha4beta1 integrin ligands vascular cell adhesion mole
69 that aberrantly coexpressed alpha4beta7 and alpha4beta1 integrins, markedly decreasing local product
71 er by studying the role of growth factors on alpha4beta1 integrin-mediated adhesion of human CD34+ he
72 receptors supported robust agonist-dependent alpha4beta1 integrin-mediated adhesion of lymphocytes to
76 ect genetic evidence for essential roles for alpha4beta1 integrin-mediated cell adhesion in the migra
78 type I PKA is important for localization of alpha4beta1 integrin-mediated PKA activation at the lead
80 We have examined the relationship between alpha4beta1-integrin-mediated adhesion and growth of CD3
81 ing segment-1 (CS1)-binding domain of FN and alpha4beta1 integrin on circulating cells may interfere
82 ing segment-1 (CS1)-binding domain of FN and alpha4beta1 integrin on circulating cells may prevent th
83 ic db/db ECs was mediated by interactions of alpha4beta1 integrin on monocytes with endothelial vascu
85 esent evidence that interactions between the alpha4beta1 integrin on sympathetic neurons and vascular
86 and TSP1 inhibited interaction of activated alpha4beta1 integrin on T cells with its counter recepto
90 del in which in vivo interaction between the alpha4beta1 integrin receptor and the cell-associated CS
92 the spatiotemporal organization of activated alpha4beta1 integrins regulates T lymphocyte adhesion.
94 entify a novel mechanism in T-cells by which alpha4beta1 integrin signaling drives specific chromatin
95 study suggests that cooperative alpha5beta1/alpha4beta1 integrin signaling may be regulated by ILK t
96 iated HTM cells could be rescued by inducing alpha4beta1 integrin signaling with a recombinant Hep II
97 nectin were used to activate alpha5beta1 and alpha4beta1 integrin signaling, respectively, in differe
100 dition to its recognition by alpha3beta1 and alpha4beta1 integrins, the N-terminal pentraxin module o
101 failure of PC/pvSMCs, which normally express alpha4beta1 integrin, to spread uniformly along the vess
103 ion cascade, which includes L-selectin/PNAd, alpha4beta1 integrin/VCAM-1, and LFA-1, targets specific
109 endothelial cells through the interaction of alpha4beta1 integrin with endothelial Lutheran/basal cel
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