ライフサイエンスコーパス: altered gene expression

1 reflects changes in cellular composition and altered gene expression.

2 ained from cytogenetics, gene mutations, and altered gene expression.

3 phenotypes of ADAR mutants can be caused by altered gene expression.

4 further to aberrant chromatin remodeling and altered gene expression.

5 a model of aberrant DNA repair coupled with altered gene expression.

6 Breast cancer progression is driven by altered gene expression.

7 sults in cell proliferation and dramatically altered gene expression.

8 to drug-induced and idiopathic lupus through altered gene expression.

9 uld directly transmute synaptic signals into altered gene expression.

10 eir concentration in the nucleus, leading to altered gene expression.

11 s show increased sarcomeric organization and altered gene expression.

12 ic hyperglycemia is the primary cause of the altered gene expression.

13 of CD40 are believed to be achieved through altered gene expression.

14 proteasome-mediated degradation rather than altered gene expression.

15 es and cause epigenetic changes that lead to altered gene expression.

16 preventing pleiotropic effects caused by its altered gene expression.

17 geted disruption of such elements results in altered gene expression.

18 promotes erythroid development, and reverses altered gene expression.

19 In contrast, it altered gene expression.

20 oth LOE genes and ASE events associated with altered gene expression.

21 n by inhibiting DNMT1 activity, resulting in altered gene expression.

22 eased proliferation, aberrant apoptosis, and altered gene expression.

23 APEX1 binding at -1651 of CYP11B2 results in altered gene expression.

24 adversely affected by TNFalpha, resulting in altered gene expression.

25 localization of heterochromatin, leading to altered gene expression.

26 ed changes in nucleosome occupancy result in altered gene expression?

27 t the idea that Cdk5 activity is involved in altered gene expression after chronic exposure to cocain

28 s provides the first comparative analysis of altered gene expression after infection with viruses of

29 In general, pair feeding altered gene expression after the 7-day treatment, where

30 iminution in stem cell pools, or, because of altered gene expression, an increased chance for stem ce

31 the two-week time point and correlated with altered gene expression and 5hmC profiles that mapped to

32 single Drosophila homolog dBRWD3 results in altered gene expression and aberrant patterns of histone

33 strides have been made in characterizing the altered gene expression and acquired genetic mutations i

34 F-beta1 gene promoter may be associated with altered gene expression and asthma phenotype.

35 n, the signal transduction events leading to altered gene expression and cellular activity are essent

36 tially mediate signaling events that lead to altered gene expression and cellular function, and may r

37 isms that translate radiation responses into altered gene expression and cellular phenotype.

38 or cells that GDM exposure in utero leads to altered gene expression and DNA methylation, suggesting

39 tating OFT and associated vessels results in altered gene expression and function of CNCCs and decrea

40 stress-inducible gene, in the heart leads to altered gene expression and impaired cardiac function.

41 d during differentiation, and TET1 knockdown altered gene expression and inhibited barrier formation

42 oxylase, providing a functional link between altered gene expression and intrinsic abnormalities in P

43 loci have variants that could contribute to altered gene expression and liability.

44 Changes in diet result in altered gene expression and neuronal activity in the ARN

45 tic bases for differential susceptibility to altered gene expression and NTDs in diabetic mice may be

46 h SMC-specific knockdown of Mylk demonstrate altered gene expression and pathology consistent with me

47 pe III methyltransferases is associated with altered gene expression and phenotypic variation.

48 e molecular effects of TE movements, such as altered gene expression and piRNA production.

49 with chromatin by depleting WIZ resulted in altered gene expression and protein-protein interactions

50 in sickle cell disease (SCD) contributes to altered gene expression and pulmonary hypertension, a co

51 lly active Dnmt1, lens epithelial cells have altered gene expression and reduced proliferation in bot

52 Altered gene expression and slight interstitial fibrosis

53 Epigenetic mechanisms contribute further to altered gene expression and therefore to the development

54 ncluding changes in DNA methylation, lead to altered gene expression and thus may underlie epileptoge

55 y 2,3,7,8-tetrachlorodibenzo-p-dioxin causes altered gene expression and toxicity.

56 -p-dioxin (TCDD) and related compounds cause altered gene expression and toxicity.

57 7,8-tetrachlorodibenzo-p-dioxin (TCDD) cause altered gene expression and toxicity.

58 d associations of five of the GWAS loci with altered gene expression and two with CAD.

59 ime, begin to form duct-like structures with altered gene expression and ultrastructural properties.

60 sults in re-initiation of the DNA synthesis, altered gene expression, and apoptosis, but the signalin

61 -variant positive tumours have significantly altered gene expression, and are enriched for the lumina

62 RNase protection assay was used to measure altered gene expression, and enzyme-linked immunosorbent

63 r, these data link RS-mediated mtDNA damage, altered gene expression, and mitochondrial dysfunction i

64 ith those of the present study, suggest that altered gene expression, and not actin reorganization, i

65 lic changes resulting from genetic mutation, altered gene expression, and protein dysfunction in a gi

66 en MGEs can compromise bacterial fitness via altered gene expression, and we argue that conflicts bet

67 that IL6 promoter genotypes associated with altered gene expression are risk factors for development

68 DNMT3B7-expressing 293 cells have altered gene expression as identified by microarray anal

69 rough tyrosine kinase activation may lead to altered gene expression, as J393/CD43 ligation prompted

70 To detect altered gene expression associated with mouse lung tumor

71 We identified altered gene expression at all ages, including changes i

72 ethylated promoters that are associated with altered gene expression between neural stem cell (NSC) a

73 We found specific patterns of altered gene expression between TAC and SIH with GRK5 ov

74 ats perfused 5-7 d after TT injection showed altered gene expression, but the changes varied in their

75 The mechanisms of cell signaling and altered gene expression by asbestos, a potent inflammato

76 Both processes are also modulated by altered gene expression by resident cells and by the rel

77 in genetic programming is unclear; however, altered gene expression by temperature-dependent changes

78 of genome-wide DNA methylation levels and of altered gene expression caused by epialleles.

79 ity, and examination for genetic mutation or altered gene expression characteristics of the correspon

80 RNA miR-22 motif) and promoter polymorphisms altered gene expression consistent with the decline in S

81 d by surface changes, uptake, signaling, and altered gene expression, contributing to homeostasis, ho

82 haracterized by transient cell cycle arrest, altered gene expression, degradation of nutrient permeas

83 with renal cells has been shown to result in altered gene expression, DNA synthesis, and cell death.

84 develops dysfunction, reduction in mass, and altered gene expression, due to atrophic remodeling.

85 has been strengthened through description of altered gene expression during biotin deficiency and thr

86 cause familial forms of the disease, and 2) altered gene expression during the disease state.

87 In addition, the phenotypes resulting from altered gene expression (e.g. in genetically altered ani

88 d by HER2 overexpression activated Stat3 and altered gene expression, enforcing an autocrine loop of

89 ion, five polymorphisms were associated with altered gene expression following doxorubicin treatment.

90 Altered gene expression for a number of molecules has be

91 s respond to traumatic brain injury (TBI) by altered gene expression, hypertrophy and proliferation t

92 this new gene expression screen to identify altered gene expression in a complex in vivo environment

93 Cellular exposure to hypoxia results in altered gene expression in a range of physiologic and pa

94 The mechanism by which altered gene expression in adipose tissue affects liver

95 Together our results show: (a) an altered gene expression in carriers of the susceptible C

96 ant promoter methylation was associated with altered gene expression in CRC, this was not the case in

97 Finally, we successfully altered gene expression in cultured human PAX7+ satellit

98 equencing unveiled morphological changes and altered gene expression in deletion mutants of two N-myr

99 mals and allows evaluation of the effects of altered gene expression in differentiated cell types in

100 e characteristic drug 'signature' pattern of altered gene expression in drug-treated cells with a mut

101 Altered gene expression in hematopoietic progenitors may

102 of these were significantly associated with altered gene expression in human adipose, more than woul

103 o examine how wild-type (wt) HPIV1 infection altered gene expression in human respiratory epithelial

104 This comprehensive description of altered gene expression in isolated IPF fibroblasts unde

105 letion in the gene for PML (KO mice) exhibit altered gene expression in liver, adipose tissue, and sk

106 upregulation of genes involved in apoptosis, altered gene expression in metabolic pathways, and the d

107 establish DNA methylation as a mechanism of altered gene expression in MS hippocampus.

108 Probiotic ingestion altered gene expression in multiple canonical pathways i

109 Our data provide a basis for studying altered gene expression in myeloid disorders using mouse

110 l association between RB-E2F dysfunction and altered gene expression in osteosarcoma.

111 The most significantly altered gene expression in patients with PTSD relative t

112 Furthermore, this variant is associated with altered gene expression in peripheral blood and altered

113 ngle-cell antisense RNA approach to identify altered gene expression in postmortem AD brain, followed

114 leading to increased protein acetylation and altered gene expression in prostate and ovarian cancer c

115 used to profile transcriptomes and discover altered gene expression in saliva supernatant.

116 Wound repair in the liver induces altered gene expression in stellate cells (resident mese

117 The aim was to identify the extent of altered gene expression in term placentas from pregnant

118 at the absence of SigB or SigD predominately altered gene expression in the dark or in the light, res

119 rapid appearance of periodic arrangements of altered gene expression in the epidermis and prominent c

120 maternal nutrient restriction significantly altered gene expression in the fetal cardiac left ventri

121 nd MEF2C each programmed similar profiles of altered gene expression in the heart that included extra

122 terning allows a better understanding of how altered gene expression in the hippocampus contributes t

123 est an important role for decreased ARNT and altered gene expression in the impaired islet function o

124 ese changes in cell fate are associated with altered gene expression in the intestine and remodeling

125 y of >5000 mouse expressed sequence tags for altered gene expression in the livers of two lines of mi

126 ing and interfered with DNA looping, causing altered gene expression in the neighboring loop.

127 e response is usually manifested in terms of altered gene expression in the nucleus.

128 pread epigenetic instability associated with altered gene expression in the placentas of wild-type gr

129 frequently accompanied by hypometabolism and altered gene expression in the prefrontal cortex.

130 Altered gene expression in this tissue does not appear t

131 We showed altered gene expression in TILs in FL and demonstrated t

132 by microarray analysis to be involved in the altered gene expression in vectorless gravity, the data

133 ohol dehydrogenase (ADHIB) and evaluated for altered gene expression in vitro and metabolic activity

134 Adhesion to OPN altered gene expression, in particular genes involved wi

135 Biological pathways showing early altered gene expression included: lipid metabolism, cyto

136 cted as changes in synaptic transmission and altered gene expression, indicating that restoring synap

137 The altered gene expression is associated with dysregulated

138 re weeks to develop in rats, suggesting that altered gene expression is involved.

139 Altered gene expression is presumed to be due to interac

140 sought to determine whether this pattern of altered gene expression is restricted to the dorsolatera

141 from both injury models, at least 50% of the altered gene expression is specific to a given injury ty

142 rogenitors and erythropoiesis, indicating an altered gene-expression landscape.

143 This deficiency results in altered gene expression leading to physiological and mor

144 ve sarcoplasmic reticulum Ca(2+) release and altered gene expression, leads to cardiac hypertrophy an

145 The lack of LMO2 resulted in altered gene expression levels already at the haemangiob

146 These phenotypes are associated with the altered gene expression levels of FCA, WUS, and CUC1.

147 In non-stroke animals gemfibrozil also altered gene expression levels of PPARs in both the aort

148 bitor-mediated changes were not reflected in altered gene expression levels of the genes involved in

149 to identify associations between smoking and altered gene expression levels.

150 iptional effect level index) that integrates altered gene expression magnitude over the exposure time

151 studies have shown that integration-induced altered gene expression may be associated with tumor rec

152 Altered gene expression may be the earliest mediator of

153 These findings suggest that altered gene expression may result from the interactions

154 To determine whether altered gene expression might account for long term chan

155 This altered gene expression might suggest a role for ADIPOR1

156 atin in an imbalanced manner, it can lead to altered gene expression, mitotic errors, and death [4-6]

157 rmal monocyte gene-expression levels with an altered gene-expression network due to gene-environment

158 n murine lung tumors and its relationship to altered gene expression observed during embryogenesis an

159 ted with systemic lupus erythematosus (SLE), altered gene expression of C1QB and five type I interfer

160 trix (Santa Clara, CA) gene chip technology, altered gene expression of different end effector molecu

161 lection of aggressively expanding cells with altered gene expression of integrated HPV genomes and po

162 ys became prominent in TGo, concomitant with altered gene expression of K(+)-channel subunits and ion

163 Morphological diversity is often caused by altered gene expression of key developmental regulators.

164 Furthermore, B4 knockdown altered gene expression of key genes of lens differentia

165 metabolic disorders in the F1 offspring and altered gene expression of metabolic pathways in early e

166 e to reduced mitochondrial Ca(2+) uptake and altered gene expression of proapoptotic and antiapoptoti

167 We found altered gene expression of various cell cycle regulators

168 ticularly useful for studying the effects of altered gene expression on cardiac development and in th

169 s development, physiology or defence through altered gene expression or by direct influences on other

170 eoplasms is often associated with mutations, altered gene expression or chromosomal translocations.

171 ntrolling plant development, which result in altered gene expression or loss of gene function.

172 based diagnosis tools for diseases caused by altered gene expression, or used for further network ana

173 igand rosiglitazone partially normalizes the altered gene expression pattern associated with Cftr def

174 ors carrying the GFI136N variant allele have altered gene expression patterns and differ in their abi

175 In various human diseases, altered gene expression patterns are often the result of

176 Recently, using cDNA microarrays, altered gene expression patterns between subjects with s

177 rst exons is known to play a key role in the altered gene expression patterns in all human cancers.

178 acterial and viral infections, respectively, altered gene expression patterns in taste bud cells.

179 in the forebrain neuroectoderm, we observed altered gene expression patterns in the facial ectoderm.

180 her they shared functional abnormalities and altered gene expression patterns that differed from thos

181 analyses provide a high-quality resource of altered gene expression patterns under severe OXPHOS def

182 rmore, we show that the Osr2 mutants exhibit altered gene expression patterns, including those of Osr

183 1 leads to epithelial cell proliferation and altered gene expression patterns.

184 gan pathology, biochemical abnormalities and altered gene expression patterns.

185 process resulting in contaminated cells with altered gene expression patterns.

186 s prevented adaptation, suggesting that Mdm2 altered gene expression, possibly through its well known

187 The findings of altered gene expression prior to the development of any

188 lecular synergy manifested as a dramatically altered gene expression profile in Npm1(cA);Flt3(ITD) ,

189 RNA from null and wild-type mice revealed an altered gene expression profile with the up-regulation o

190 and pro-inflammatory features matched by an altered gene expression profile.

191 R expression in human RKO colon cancer cells altered gene expression profiles and identified beta-cat

192 e placental disruptions were associated with altered gene expression profiles in the male fetal brain

193 r in Western societies, dietary-induced risk altered gene expression profiles predominantly in villus

194 ) cells had reduced suppressor activity with altered gene expression profiles, including reduced expr

195 ylase chromatin remodeling complex, leads to altered gene expression profiles.

196 icromol/L, respectively, and correlated with altered gene expression profiles.

197 An analysis of the temporal sequence of altered gene expression provides further information tha

198 CRF and GR gene methylation correlated with altered gene expression, providing important evidence of

199 Another one employs an integrated altered gene expression quantifier-TELI (transcriptional

200 Like contextual memory formation, this altered gene expression required NMDA receptor activatio

201 e at relatively hypomethylated loci, and the altered gene expression resulted from de novo centromere

202 impairs insulin-mediated NO production, and altered gene expression resulted from eNOS instability,

203 Altered gene expression resulting from YAP/TAZ inhibitio

204 cterized by chromosomal abnormalities and an altered gene expression signature; however, the mechanis

205 hen expressed, it promotes tumorigenesis via altered gene expression, stimulating epithelial-mesenchy

206 The mechanism of HAH toxicity involves altered gene expression subsequent to activation of the

207 T1pSer143 that regulates DNA methylation and altered gene expression that contributes to cell invasio

208 rm development based on the dynamics of SHB1-altered gene expression, the magnitude of SHB1 chromatin

209 in Jmjd3-deficient cells are correlated with altered gene expression through interactions with specif

210 One possible consequence of aneuploidy is altered gene expression through loss of heterozygosity (

211 thus enabling transfection experiments that altered gene expression to explore the molecular mechani

212 n primary afferent neurons to result from an altered gene expression triggered by cytokines/growth fa

213 hances tumor growth in cholangiocarcinoma by altered gene expression via autocrine mechanisms.

214 Altered gene expression was confirmed by quantitative PC

215 Functional classification of altered gene expression was consistent with a role for S

216 Altered gene expression was consistent with CDK8/19 inhi

217 es were identified, the temporal sequence of altered gene expression was determined by monitoring the

218 Significantly altered gene expression was determined by multiclass ana

219 This altered gene expression was discovered by microarray ana

220 The altered gene expression was partly due to glucose restri

221 The altered gene expression was partly rescued by knockdown

222 In light of this altered gene expression, we probed the effects of these

223 Significant and bidirectional predictions of altered gene expression were identified in amygdala betw

224 ivation of nuclear transcription factors and altered gene expression within the liver, leading to the

225 rization from surrounding vessels and causes altered gene expression within vascular cells.