ライフサイエンスコーパス: alternate conformation

1 studied superhelical transitions to a single alternate conformation.

2 formers, but in the crystal both adopt a 1,2-alternate conformation.

3 ne-like conformation, and HC6.Cs has a 1,2,3-alternate conformation.

4 oxocalix[4]arene adopts in the crystal a 1,2-alternate conformation.

5 ying simulation where the simulation samples alternate conformations.

6 otein pocket, allowing for rapid sampling of alternate conformations.

7 state among a vast ensemble of unfolded and alternate conformations.

8 tain the phospho-accepting His45 do not have alternate conformations.

9 r in the identity of side-chains that occupy alternate conformations.

10 posal that OmpA can fold into one of the two alternate conformations.

11 molecules hydrating the oligonucleotide have alternate conformations.

12 cture, the hemiphthaloyl ring occupies three alternate conformations.

13 Four side-chains display alternate conformations.

14 he ES enzyme, a mutated Omega loop adopts an alternate conformation allowing the side chain to be muc

15 Calix[4]arenes constrained to the 1,3-alternate conformation and functionalized at the upper r

16 Cys side chains of (CSL9C)(3) show alternate conformations and are partially preorganized f

17 A) was studied as a function of resolution, alternate conformations, and temperature factor (B), lea

18 The alternate conformations are most likely the result of th

19 For the C-terminal domain of protein IX two alternate conformations are proposed, either binding on

20 hosphorylation of DNA-bound CREB promotes an alternate conformation characterized by an apparent incr

21 that the Asp318 side chain exhibits a minor alternate conformation, compared to that in the wild typ

22 n, as a disease-causing mutation leads to an alternate conformation completely incapable of hydrolyzi

23 The accessible alternate conformations depend on base sequence and comp

24 icated that Trp104 is capable of undertaking alternate conformations depending on the length of the B

25 The alternate conformation, described by Kuriyan and co-work

26 of dimers, the helicase domain exists in two alternate conformations, each of which can form symmetri

27 Thus, there must exist an alternate conformation for LeuT in which the substrate i

28 Mn(2+).UDP.phosphoglyceric acid revealed an alternate conformation for the nucleotide sugar beta-pho

29 lectron density maps has enabled modeling of alternate conformations for 83 residues in the enzyme, m

30 ed structure-activity relationships and used alternate conformations from a crystallographic structur

31 the cytoplasmic accessibility pathway of the alternate conformation in a mammalian serotonin transpor

32 ation in the ER membranes changes SCAP to an alternate conformation in which it binds ER retention pr

33 petitive behavior of transitions to multiple alternate conformations in a negatively supercoiled DNA

34 ecognized, the overall significance of these alternate conformations in biology has only recently bec

35 the inherent ability of the H3 tail to adopt alternate conformations in complex with chromatin regula

36 133 and AppA1-126 contain Trp104 in distinct alternate conformations in solution and that light absor

37 Resolving the alternate conformations in the active site residues prov

38 Two of the metal ligands adopt alternate conformations in the crystal structure, both c

39 hydroxylase, caused by the occurrence of two alternate conformations in the hinge region that leads t

40 ate sidechain rotamer jumps, as evidenced by alternate conformations in very high-resolution crystal

41 In the unbound state, DtpA adopts two main alternate conformations in which transmembrane alpha-hel

42 ts show that recombinant alpha-chain assumes alternating conformations in the absence of beta-chain a

43 calix[4]arene, neither the cone nor the 1,2-alternate conformation is computed to be a ground-state

44 considerable importance, but distinguishing alternate conformations is a challenge.

45 are discussed within the context of a C1/C2 alternating conformation model in which lactose transloc

46 This alternate conformation now causes a steric hindrance to

47 E256Q mutant with putrescine added shows an alternate conformation of His243, Glu11, Lys80, and Ser2

48 The C319Y protein exhibits an alternate conformation of the flap, explaining its lack

49 partner monomer is incompletely occupied, an alternate conformation of the loop involving residues 12

50 These structures reveal an alternate conformation of the microtubule binding region

51 rphyrin, prepared in 91% yield, shows an 1,3-alternate conformation of the molecule with partial over

52 tinguished by a projecting beta-shelf and an alternate conformation of the N-terminal polypeptide.

53 The pincer-like 1,3-alternate conformation of the oxacalix[4]arene scaffold,

54 domain, whereas arachidonic acid prompts an alternate conformation of the TPR domain, destabilising

55 Alternate conformations of Asn214 near the active site a

56 SCOR also presents the predominant and alternate conformations of hairpin loops, as shown in th

57 ee energy differences between at least a few alternate conformations of many proteins are not large.

58 acting NAD(H)-NADPH pairs are observed where alternate conformations of the NAD(H) phosphodiester and

59 nts displayed small local perturbations with alternate conformations of the Ser side chains.

60 n contrast to the wild-type protein, several alternate conformations of the substrate, confirming tha

61 and to obtain more accurate descriptions of alternate conformations of the two proteins, we first pe

62 t is suggested that these signals arise from alternate conformations of Trp191 having different degre

63 main of this group of enzymes, exists in two alternate conformations, only one of which makes the enz

64 es would not be analyzed for residues in 'b' alternate conformations or with B-factors of 40 or above

65 ermined and if no atom had a B factor >/=40, alternate conformation, or severe clash; that selection

66 Thus, both TCR V-domains can switch among alternate conformations, perhaps extending their ability

67 l group, 4.4 A from the heme Fe, whereas the alternate conformation positions the second, infrequent

68 , it is unique in that NADP+ is bound in two alternate conformations, probably because of the lack of

69 n the dengue virus family, with the reported alternate conformation resulting from a unique metal-bin

70 In addition, an alternate conformation similar to the omega-helix forms

71 th data from the reactivation kinetics, this alternate conformation suggests a key interaction betwee

72 he inactive state is a biologically relevant alternate conformation that regulates ribosome function

73 lements confer unique phenotypes by adopting alternate conformations that specify new traits.

74 e resistant, supporting a transition from an alternate conformation to a well packed triple helix.

75 molecules, resulting in the formation of an alternate conformation to standard B-DNA known as B'-DNA

76 is specific for cytochrome c550 and utilizes alternate conformations to recognize redox partners.

77 s 1 and 2, possessing either a cone or a 1,3-alternate conformation, to NO(2)/N(2)O(4), both in chlor

78 he possibility that this region may adopt an alternate conformation upon DNA binding.

79 The alternate conformation was correlated with protonation o

80 of DADH in complex with iminohistidine, two alternate conformations were observed for iminohistidine

81 binding is required for stabilization of the alternate conformation, which catalyzes the 4-CBA-CoA th

82 cture of reduced P94A amicyanin exhibits two alternate conformations with the positions of the copper

83 The reduced P94A amicyanin exhibits two alternate conformations with the positions of the copper

84 Each DNA helix is quite anisotropic, and alternate conformations, with motion in the direction of