ライフサイエンスコーパス: alternatively activated macrophage

1 mponents of the HA system and no clusters of alternatively activated macrophages.

2 pe C-type lectin 1 (MGL1/CD301), a marker of alternatively activated macrophages.

3 3, and -4 to interferon-gamma ratio), and 4) alternatively activated macrophages.

4 hile intestinal inflammation is regulated by alternatively activated macrophages.

5 ages assume a distinct phenotype, designated alternatively activated macrophages.

6 h a mechanism that involves the induction of alternatively activated macrophages.

7 that PPARgamma is required for maturation of alternatively activated macrophages.

8 a of F4/80+ cells that have the phenotype of alternatively activated macrophages.

9 duced IL-4 receptor(hi) (IL-4R(hi)) CD206(+) alternatively activated macrophages.

10 macrophages and an increase in the number of alternatively activated macrophages.

11 lassical monocytes are biased progenitors of alternatively activated macrophages.

12 ctivity in infected lungs, characteristic of alternatively activated macrophages.

13 oxidase activity, which is characteristic of alternatively activated macrophages.

14 ibrosis and displayed a diminished number of alternatively activated macrophages.

15 ung neutropenia and enhanced accumulation of alternatively activated macrophages.

16 d with an altered cytokine profile and fewer alternatively activated macrophages.

17 type 2 cytokines interleukin (IL)-4/13, and alternatively activated macrophages.

18 (ArgI, Retnla, and Chi3l3) characteristic of alternatively activated macrophages.

19 se-type C-type lectin 1 (MGL-1), a marker of alternatively activated macrophages.

20 on with Ft LVS also resulted in induction of alternatively activated macrophages (AA-Mphi).

21 n endotoxin tolerance and differentiation of alternatively activated macrophages (AA-MPhis or M2), we

22 In the lung, alternatively activated macrophages (AAM) form the first

23 mice with worms resulted in the induction of alternatively activated macrophages (AAM) within the per

24 Differentiation and recruitment of alternatively activated macrophages (AAMacs) are hallmar

25 at favors the production of higher levels of alternatively activated macrophages (AAMacs) compared wi

26 In turn, these alternatively activated macrophages (AAMacs) functioned

27 Alternatively activated macrophages (AAMPhi) are found i

28 t generated in immunocompromised hosts whose alternatively activated macrophages (AAMphi) predominate

29 was not required for the differentiation of alternatively activated macrophages (AAMPhi) that expres

30 e SIRS mice exhibited typical properties for alternatively activated macrophages (AAMphi).

31 nonuclear cells results in the generation of alternatively activated macrophages (AAMphi).

32 These macrophages are referred to as alternatively activated macrophages (AAMPhis) as they ex

33 oduced the protein Ym1, which is a marker of alternatively activated macrophages (aaMphis), in an IL-

34 Unlike acute pancreatitis (AP), we find that alternatively activated macrophages (AAMs) are dominant

35 une regulation of helminth infections and as alternatively activated macrophages (AAMs) are thought t

36 Markers of alternatively activated macrophages (AAMs) are upregulat

37 Additionally, alternatively activated macrophages (AAMs) expressing AD

38 YM1, FIZZ1, and Arg1, indicating a role for alternatively activated macrophages (AAMs) in pulmonary

39 environment resulted in the accumulation of alternatively activated macrophages (AAMs) in the lung.

40 us survives and replicates preferentially in alternatively activated macrophages (AAMs), which are mo

41 ecessary for accumulation of eosinophils and alternatively activated macrophages (AAMs).

42 metabolic homeostasis and the maintenance of alternatively activated macrophages (AAMs).

43 unity and allergy, often in conjunction with alternatively activated macrophages (AAMs).

44 The balance between alternatively activated macrophages (AAMs)/M2 cells and

45 rive the differentiation of macrophages into alternatively activated macrophages (aaMs, also referred

46 Alternatively, activated macrophages (AAMs) contribute t

47 Alternatively activated macrophages (AAMvarphi) are a ma

48 Alternatively activated macrophages (AAMvarphis) have be

49 e data demonstrate that both classically and alternatively activated macrophages accumulate in the li

50 y, Il5 (Tg) /Cd300f (-/-) mice had increased alternatively activated macrophage accumulation in the a

51 HIF1A up-regulates the ADORA2B receptor on alternatively activated macrophages and contributes to p

52 ages secrete more TNFalpha and IL-1beta than alternatively activated macrophages and dramatically acc

53 ress and Wnt signaling, the contributions of alternatively activated macrophages and efferocytosis, t

54 M-2 is expressed on newly differentiated and alternatively activated macrophages and functions to res

55 e induced by Th2 cytokines, is a hallmark of alternatively activated macrophages and is responsible f

56 mans, as measured by survival, but had fewer alternatively activated macrophages and less inflammatio

57 Fusion of alternatively activated macrophages and osteoclasts is a

58 oducing CD4(+) T cells and F4/80(+) CD206(+) alternatively activated macrophages and prevented the ap

59 described innate lymphoid cells, as well as alternatively activated macrophages and pulmonary stem c

60 t associated with increases in the levels of alternatively activated macrophages and T regulatory cel

61 Loss of CD73 prevents accumulation of alternatively activated macrophages and the formation of

62 he understanding of IL-4- and IL-13-mediated alternatively activated macrophages and type 2 immune re

63 5ac, Clca3, and RELMbeta, differentiation of alternatively activated macrophages, and airway hyperrea

64 mphocytes, myeloid-derived suppressor cells, alternatively activated macrophages, and dendritic cells

65 -12p40, TNF, and IFN-gamma, fail to generate alternatively activated macrophages, and develop endotox

66 ssociated with Th2-type cytokine production, alternatively activated macrophages, and inability of th

67 E production, basophilia, differentiation of alternatively activated macrophages, and protection agai

68 Alternatively, activated macrophages appear earlier than

69 Alternatively activated macrophages are a key effector c

70 en or IL-4 demonstrated that marker genes of alternatively activated macrophages are differentially r

71 Tumor stromal alternatively activated macrophages are important determ

72 ed expression of other genes associated with alternatively activated macrophages, as well as increase

73 Elimination of alternatively activated macrophages blocked smooth muscl

74 -13Ralpha1 contributes to the development of alternatively activated macrophages, but the type 1 IL-4

75 changes were associated with an increase in alternatively activated macrophages concomitant with enh

76 sion, TGF-beta production, and activation of alternatively activated macrophages, contributed by dere

77 tinase-like molecule that is associated with alternatively activated macrophages, could partially res

78 s from wild-type c57BL/6NcR mice accumulated alternatively-activated macrophages, displayed elevated

79 Thus, we conclude that alternatively activated macrophages do not synthesize re

80 etory protein that is transiently induced in alternatively activated macrophages during T-helper (Th)

81 Alternatively activated macrophages express the pattern

82 pe cytokine production, and the induction of alternatively activated macrophages expressing arginase-

83 t and demonstrated a transient population of alternatively activated macrophages expressing stabilin-

84 r, the requirement for either classically or alternatively activated macrophages for Pneumocystis cle

85 o, MR deficiency synergized with inducers of alternatively activated macrophages (for example, IL-4 a

86 Together, our findings suggest that resident alternatively activated macrophages have a beneficial ro

87 -deficient mice is marked by accumulation of alternatively activated macrophages, higher collagen dep

88 om GM(+/+) mice showed numerous hallmarks of alternatively activated macrophages: higher numbers of i

89 d non-classical monocytes as contributors to alternatively activated macrophages, highlighting them a

90 Absence of alternatively activated macrophages impaired metabolic a

91 otype of Ati-CB1-KO mice and the increase in alternatively activated macrophages in adipose tissue we

92 e findings reveal a role for type I IFNs and alternatively activated macrophages in aggressive prolif

93 s our understanding of the potential role of alternatively activated macrophages in atherogenesis and

94 Emerging evidence indicates that alternatively activated macrophages in central nervous s

95 set to gain deeper insights into the role of alternatively activated macrophages in immunobiology.

96 pacity to repair tissue, the precise role of alternatively activated macrophages in obesity-induced i

97 We speculate that accumulation of alternatively activated macrophages in organized cluster

98 ate lymphoid cells (ILC2s), eosinophils, and alternatively activated macrophages in the adipose tissu

99 , increased Th2 cytokine milieu, and induced alternatively activated macrophages in the gut.

100 f type 2 pulmonary innate lymphoid cells and alternatively activated macrophages in the lungs as well

101 Thus, we have discovered a role for alternatively activated macrophages in the orchestration

102 cryptococci and YM1 crystals, indicative of alternatively activated macrophages in these mice.

103 ced rapid recruitment and differentiation of alternatively activated macrophages in vivo, through IL-

104 sed arginase1 and Ym1 expression, typical of alternatively activated macrophages, in the draining (ce

105 ntrahepatic expression of genes expressed by alternatively activated macrophages, including CD206, Re

106 xpressed many genes characteristic of M2 or "alternatively activated" macrophages, including Ym1, arg

107 es or M1, induced by IFN-gamma plus LPS, and alternatively activated macrophages, induced by IL-4.

108 pe I and type II NKT cells, eosinophils, and alternatively activated macrophages into the VAT.

109 of regenerative wound-healing macrophages as alternatively activated macrophages is currently questio

110 ty and classically activated macrophage (M1)-alternatively activated macrophage (M2) polarization.

111 e activates macrophage Gpr132 to promote the alternatively activated macrophage (M2)-like phenotype,

112 M1 macrophages) are proinflammatory, whereas alternatively activated macrophages (M2 macrophages) are

113 Alternatively activated macrophages (M2) have an importa

114 in response to chitosan than intermediate or alternatively activated macrophages (M2).

115 activated macrophages [M1] and expansion in alternatively activated macrophages [M2]), which could i

116 trite levels, and reduced apoptosis, whereas alternatively activated macrophage markers are unchanged

117 nfiltration of macrophages and up-regulation alternatively activated macrophage markers by a mechanis

118 els in the organs, reduced the expression of alternatively activated macrophage markers, and increase

119 Inhibition or depletion of Arg did not alter alternatively activated macrophage numbers but instead w

120 In thioglycollate-elicited and alternatively activated macrophages, PGE2 selectively im

121 inflammatory, profibrotic, and dysfunctional alternatively activated macrophage phenotype possibly vi

122 ), an established marker of the IL-4-induced alternatively activated macrophage phenotype.

123 nfiltrating blood monocytes toward an M2 or "alternatively" activated macrophage phenotype could prom

124 ned by the local immune environment and that alternatively activated macrophages play a major role in

125 monstrate that pink-staining eosinophils and alternatively activated macrophages play key roles in an

126 , classically activated macrophages; PMN-II, alternatively activated macrophages; PMN-N, no effect on

127 Alternatively activated macrophages prevent lethal intes

128 , a major product of IL-4- and IL-13-induced alternatively activated macrophages, prevents cachexia,

129 ifically lacking in Retnla, a characteristic alternatively activated macrophage product associated wi

130 ral cytokines, chemokines, and markers of an alternatively activated macrophage response.

131 egulate adaptive immunity and eosinophil and alternatively activated macrophage responses, and were r

132 Therefore, alternatively activated macrophages restrain NK cell act

133 Here, we show that an alternatively activated macrophage secreted enzyme, inte

134 h PKD1 and PKD2, abnormally large numbers of alternatively activated macrophages surrounded the cysts

135 Alternatively activated macrophages, TAMs, are an abunda

136 iased immune response and the development of alternatively activated macrophages that mediate a profi

137 t the increased levels of glucose present in alternatively activated macrophages to sustain chronic i

138 n T-cell and macrophage polarization from T2/alternatively activated macrophages toward T1/classicall

139 GL2), a lectin commonly used as a marker for alternatively activated macrophages, was selectively exp

140 h2-type cytokine production and induction of alternatively activated macrophages were also observed i

141 These alternatively activated macrophages were also shown to h

142 addition, alpha-MSH promotes survival of the alternatively activated macrophages where without alpha-

143 duced intestinal pathology or development of alternatively activated macrophages, which are required

144 neoformans, including enhanced generation of alternatively activated macrophages, which is accompanie

145 P2Y agonists in thioglycollate-elicited and alternatively activated macrophages, which provide new c

146 d CD163 consistent with differentiation into alternatively activated macrophages with potential regul

147 Alveolar macrophages are prototypical alternatively activated macrophages, with up-regulated i