ライフサイエンスコーパス: alveolar cell

1 l cell polarity and functional maturation of alveolar cells.

2 he small distal airways and no expression in alveolar cells.

3 es molecular and cellular differentiation of alveolar cells.

4 eas and bronchi, with limited replication in alveolar cells.

5 critical survival factor for milk-producing alveolar cells.

6 erminal differentiation of type 1 and type 2 alveolar cells.

7 at 0.16% EtOH increased ENaC activity in rat alveolar cells.

8 nd is required for proper differentiation of alveolar cells.

9 xamined telomere length in leukocytes and in alveolar cells.

10 he retargeting of AAV-DJ vectors to distinct alveolar cells.

11 differentiated surfactant-secreting type II alveolar cells.

12 e to attach to human tracheal epithelial and alveolar cells.

13 al, secretory, ciliated, neuroendocrine, and alveolar cells.

14 sis of its phagosome and to replicate within alveolar cells.

15 RK activity was evident in airway lining and alveolar cells.

16 , cells which show characteristics of type 2 alveolar cells.

17 mainly near the basal surface of the mammary alveolar cells.

18 deficiency of adherence to the human type II alveolar cells.

19 ter after TNFalpha stimulation of A549 human alveolar cells.

20 uli of DNA synthesis in cultured rat type II alveolar cells; addition of neutralizing antibodies to H

21 nock-in allele to follow the fate of Type II alveolar cells (AEC2) in vivo.

22 AAV vector transduction occurred in alveolar cells, airway epithelial cells, and smooth musc

23 Alveolar cells and areas of atypical adenomatous hyperpl

24 tiation arrest results in the lack of type I alveolar cells and differentiated surfactant-secreting t

25 CD209L is expressed in human lung in type II alveolar cells and endothelial cells, both potential tar

26 s transgene expression to mammary ductal and alveolar cells and is nonresponsive to estrogen manipula

27 critical survival factor for milk-producing alveolar cells and, together with population models, rev

28 e was detected in pulmonary airway cells, in alveolar cells, and in small pulmonary arteries.

29 resses Elf5, a master regulatory TF gene for alveolar cells, and regulates mature luminal TF/co-facto

30 mice failed to show significant reduction in alveolar cell apoptosis and alveolar destruction after t

31 onic blockade of VEGF receptors could induce alveolar cell apoptosis and emphysema.

32 ndings suggest that inhibition of structural alveolar cell apoptosis by alpha1-antitrypsin represents

33 plasia with fibrosis, accompanied CS-induced alveolar cell apoptosis caused by enhanced TGF-beta sign

34 Alveolar cell apoptosis is involved in the pathogenesis

35 There is growing evidence that alveolar cell apoptosis plays an important role in emphy

36 significantly reduced lung oxidative stress, alveolar cell apoptosis, alveolar destruction, and pulmo

37 associated with increased RUNX3 expression, alveolar cell apoptosis, and the antiangiogenic factor G

38 ing antibodies to EMAPII resulted in reduced alveolar cell apoptosis, inflammation, and emphysema-ass

39 rolling de novo ceramide synthesis prevented alveolar cell apoptosis, oxidative stress and emphysema

40 P nick end labeling assay was used to assess alveolar cell apoptosis.

41 efenses and decreasing lung inflammation and alveolar cell apoptosis.

42 , preventing emphysema through inhibition of alveolar cells apoptosis.

43 rproliferation and lack of maturation of the alveolar cells are at least in part caused by attenuatio

44 Although bronchiolar cells and alveolar cells are proposed to be the precursor cells of

45 after T cell-target interaction, the type II alveolar cells are stimulated to produce the chemokine m

46 +) T cells, the transgene expressing type II alveolar cells, are not immediately destroyed by the eff

47 for the proliferation and differentiation of alveolar cells but also for their maintenance during lac

48 type vectors gave high transduction rates in alveolar cells but much lower rates in the airway epithe

49 large lipid droplets enclosed in the mammary alveolar cells, but milk analysis showed that these larg

50 genic IGF-I and IGFBP-3 were seen in lobular-alveolar cells by in situ hybridization.

51 fer of MDSC from naive sash mice into line 1 alveolar cell carcinoma tumor-bearing wild-type litterma

52 e, accelerated growth of transplanted line 1 alveolar cell carcinoma tumors is a mast cell-independen

53 se gaps in knowledge in a model of pulmonary alveolar cell-cell communication.

54 inflammatory response characterized by acute alveolar cell death and hyaline membrane formation, sust

55 ay play an important role in inhibiting lung alveolar cell death thereby preserving the lung architec

56 g antibody normalized TGF-beta signaling and alveolar cell death, conferring improved lung architectu

57 ands were, in part, the result of programmed alveolar cell death.

58 nts, followed by seeding these matrices with alveolar cells derived from human iPSCs.

59 nt with the phenotype, genes associated with alveolar cell differentiation and survival were differen

60 Normal fetal lung development and alveolar cell differentiation is regulated by a network

61 ure at birth due to an arrest in the type II alveolar cell differentiation program.

62 Programmed cell death (PCD) of mammary alveolar cells during involution commences within hours

63 PNECs can be colabeled with alveolar cells during lung development, and following lu

64 From E15.5 to PN20, type II alveolar cells expressed both prosurfactant protein C an

65 te pregnancy-induced mammary cell expansion, alveolar cell fate commitment, and lactogenesis.

66 m, and subsequent Notch blockade promotes an alveolar cell fate.

67 ble for the production of NO) was induced in alveolar cells from L. pneumophila-infected immunocompet

68 Apoptosis was increased in alveolar cells from transgenic mammary glands at midpreg

69 Recently, excessive apoptosis of structural alveolar cells has emerged as a major mechanism in the d

70 n 1 pathway is critical for maintaining lung alveolar cell homeostasis and that loss of its expressio

71 ogenitors are intrinsically programmed or if alveolar cell identity is determined by environmental fa

72 d the presence of APMV-1 antigen in sloughed alveolar cells in lung tissue from autopsy.

73 pecific localization of the receptor mRNA to alveolar cells in the lung and to cardiac myocytes in th

74 AAV6 vector transduced airway epithelial and alveolar cells in the lung at rates that were at least a

75 CD8(+) T cell recognition of alveolar cells in vitro triggered monocyte chemoattracta

76 d-product (sRAGE) levels, a marker of type I alveolar cell injury and BOS.

77 respiratory epithelial cells, reprogramming alveolar cells into epithelial cells with characteristic

78 The human lung alveolar cell line A549 was found to produce PGE(2) but

79 The A549 human type II alveolar cell line was cultured to confluence in RPMI 16

80 n factor ELF5 establishes the milk-secreting alveolar cell lineage by driving a cell fate decision of

81 ore, at the time that the bacteria encounter alveolar cells (macrophages and epithelial cells) in the

82 limp1 regulates proliferation, apoptosis and alveolar cell maturation during puberty and pregnancy.

83 C10(+) epithelial cells and Sftpc(+) type II alveolar cells of the adult mouse lung.

84 at maintains the bronchiolar Clara cells and alveolar cells of the distal lung and that their transfo

85 Alveolar cells of the lung are injured and killed when e

86 gest that PABCs arise preferentially from an alveolar cell population that expands during pregnancy a

87 Importantly, though, alveolar cells possess cellular repair and remodeling me

88 ht index (LWI), lung volume index (LVI), and alveolar cell proliferation index (CPI) were measured in

89 ted decreased adherence to the human type II alveolar cells, reduced nasopharyngeal colonization in i

90 ot inhibit Psa-mediated bacterial binding to alveolar cells, suggesting that both surfactant and cell

91 ed in a negative selection of differentiated alveolar cells, suggesting that Jak2 is required not onl

92 pendent, LPHA-positive vesicles in mink lung alveolar cells, suggesting that the coarse vesicles in t

93 r RLIM to exert its biological functions, as alveolar cell survival activity is inhibited in cells ex

94 dinates cellular compartments during mammary alveolar cell survival.

95 ion and milk production upon pregnancy, with alveolar cells that lack RLIM undergoing apoptosis as th

96 d C, and electron microscopic examination of alveolar cells, there was no evidence of abnormal pulmon

97 This mimicked the increased alveolar cell thickening in calves experimentally infect

98 contrast to the majority of fully committed alveolar cells, this epithelial population does not unde

99 mes in type II cell hyperplasia and atypical alveolar cells, together with the high frequency of thes

100 genitors along distinct lineages into mature alveolar cell types are still incompletely known, in par

101 vo counterparts and generate both airway and alveolar cell types in vitro.

102 sexpression prevented the differentiation of alveolar cell types.

103 MYC overexpression targeted to pulmonary alveolar cells was sufficient to induce lung adenomas an

104 ssion of ErbB2 selectively in WAP(+) mammary alveolar cells, we found that tumors had similar morphol

105 intenance of PRL-responsive, differentiating alveolar cells, we utilized a transgenic strain that exp

106 No type I alveolar cells were evident.

107 he barrier with greater efficiency when A549 alveolar cells were infected with M. tuberculosis than w

108 Alveolar cells were obtained by BAL, and BE were obtaine

109 M. tuberculosis invaded A549 type II alveolar cells with an efficiency of 2 to 3% of the init