ライフサイエンスコーパス: alveolar type II cell

1 induced growth occurs at the expense of the alveolar type II cell.

2 and are co-expressed in lung bronchiolar and alveolar type II cells.

3 induced pVHL in lung fibroblasts, but not in alveolar type II cells.

4 part with annexin A2 and lamellar bodies in alveolar type II cells.

5 anes and for lung surfactant production from alveolar type II cells.

6 y expressed in the lung, specifically within alveolar type II cells.

7 that syntaxin 2 and SNAP-23 are expressed in alveolar type II cells.

8 standing of the regulation of lipogenesis in alveolar type II cells.

9 sensitive T cell immunomodulator produced by alveolar type II cells.

10 heal epithelium while RBD-2 was expressed in alveolar type II cells.

11 surfactant secretion and uptake by isolated alveolar type II cells.

12 cient to induce expression of these genes in alveolar type II cells.

13 tagogues on the binding of iodinated SP-A to alveolar type II cells.

14 Here, we found that alveolar type II cells (AECIIs) in the lungs of IPF pati

15 per transcription factor and is expressed in alveolar type II cells, alveolar macrophages and Clara c

16 ucts were highest in Clara cells compared to alveolar Type II cells, alveolar macrophages, and small

17 Pulmonary inflammation, abnormalities in alveolar type II cell and macrophage morphology, and pul

18 on was perturbed, with a marked reduction of alveolar type II cells and a virtual absence of type I c

19 lungs from mice lacking CARM1 have immature alveolar type II cells and an absence of alveolar type I

20 aberrant expansion and signaling profile of alveolar type II cells and bronchioalveolar stem cells.

21 ted with dramatically increased apoptosis of alveolar type II cells and Clara cells, disrupted alveol

22 river leads to adenocarcinoma in a subset of alveolar type II cells and hyperplasia in the bronchioal

23 evelopment while maintaining a population of alveolar type II cells and may thus facilitate an improv

24 ants in the interaction of the molecule with alveolar type II cells and phospholipids.

25 e lung, aT is perceived to be accumulated in alveolar type II cells and secreted together with surfac

26 among retroviruses because it transforms the alveolar type II cells and the nonciliated bronchiolar c

27 tive SP-A for receptor occupancy on isolated alveolar type II cells and was a potent but nonspecific

28 ion of phosphatidylcholine (PC) secretion by alveolar type II cells), and the impact of ozone-induced

29 luding fetal hepatocytes, endothelial cells, alveolar type II cells, and aortic smooth muscle cells.

30 ted to type I cells, but is also detected in alveolar type II cells, and in tracheal and bronchial ep

31 sette transporter A3 (ABCA3) is expressed in alveolar type II cells, and the protein is localized to

32 eliorated emphysema by suppressing augmented alveolar type II cell apoptosis.

33 urfactant protein C (SP-C) is synthesized by alveolar type II cells as a 21-kDa propeptide (proSP-C21

34 lectron microscopy of affected lung revealed alveolar type II cell atypia, with numerous abnormal lam

35 dogenous genes (lamin A/C and annexin A2) in alveolar type II cells, but not other lung cells, using

36 stigators agree that solid tumors arise from alveolar type II cells, but the cellular origin of papil

37 nced endogenous annexin A2 expression in rat alveolar type II cells by RNA interference and assessed

38 idylcholine (SatPC), which is synthesized in alveolar type II cells de novo or by the deacylation-rea

39 torial fluid transport was reduced for human alveolar type II cells exposed to ALI pulmonary edema fl

40 Alveolar Type II cells express the enzyme aromatic-L-ami

41 IL-1 increased the intensity of staining of alveolar type II cells for SP-B, and the concentrations

42 l culture system in which primary human lung alveolar type II cells formed hollow epithelial cysts by

43 surrounding large airways and blood vessels, alveolar type II cells, free alveolar macrophages, and p

44 sis-mediated acute lung injury by decreasing alveolar type II cell glutathione homeostasis and functi

45 nclude that ethanol ingestion in rats alters alveolar type II cell glutathione levels and function, t

46 Idiopathic pulmonary fibrosis lung alveolar type II cells have increased MnSOD(K68) acetyla

47 SLPI mRNA was similar in whole lung and alveolar type II cells; however, it was significantly re

48 ed reduced septation, airway over-branching, alveolar type II cell hyperplasia, and disturbed vascula

49 vels of FGF-3 expression resulted in diffuse alveolar type II cell hyperplasia.

50 ological changes observed in flattening lung alveolar type II cells in culture are associated with do

51 n airway epithelial cells and was induced in alveolar type II cells in cystic fibrosis.

52 eage tracing studies showed that the ectopic alveolar type II cells in Foxm1-deficient airways were d

53 r, from day 10 there was twice the number of alveolar type II cells in mutant alveoli compared to con

54 during development and is also restricted to alveolar type II cells in the adult.

55 Cela1 was expressed predominantly in alveolar type II cells in the embryonic lung and predomi

56 a and TTF-1 were detected in bronchiolar and alveolar type II cells in the human lung.

57 nd alveolar ducts as well as macrophages and alveolar type II cells in the more distal lung.

58 D-1 was also found to be highly expressed in alveolar type II cells in vivo.

59 The secretion of lung surfactant in alveolar type II cells is a complex process involving th

60 ffected by incubation with ISO for 60 min in alveolar type II cells isolated from control and HVT ven

61 Alveolar Type II cells isolated from the lungs of rats a

62 res of rat alveolar type II cells or the rat alveolar type II cell line RLE-6TN to tumor necrosis fac

63 e antiinflammatory activity of D-4F, a human alveolar type II cell line, A549, was used.

64 posed to conditioned medium from KGF-treated alveolar type II cell (MLE-15) monolayers exhibited enha

65 n net vectorial fluid transport across human alveolar type II cell monolayers.

66 by RNA in situ hybridization in hypertrophic alveolar type II cells of carcinogen-treated A/J mice, i

67 domain (DeltaG8-P80) in the Clara cells and alveolar type II cells of SP-A(-/-) mice.

68 -MTase activity was found only in the target alveolar type II cells of the susceptible A/J mouse and

69 In vitro exposure of primary cultures of rat alveolar type II cells or the rat alveolar type II cell

70 Pulmonary alveolar type II cells produce surfactant and function a

71 was inversely proportional to the number of alveolar type II cells remaining in the lung epithelium.

72 s hABCA3 in differentiating human fetal lung alveolar type II cells resulted in abnormal, lamellar bo

73 SP-C) proprotein in multivesicular bodies of alveolar type II cells results in a 35-residue mature pe

74 In the absence of CARM1, alveolar type II cells show increased proliferation.

75 Surfactant is produced by alveolar type II cells, stored intracellularly in organe

76 onary surfactant, a material secreted by the alveolar type II cell that reduces surface tension at th

77 lipids and proteins produced and secreted by alveolar type II cells that provides the low surface ten

78 d by ADV consists of permissive infection of alveolar type II cells that results in interstitial pneu

79 tein synthesized and secreted exclusively by alveolar type II cells through proteolysis of a 21-kDa p

80 macrophages, dendritic cells, monocytes, and alveolar type II cells throughout infection.

81 (2) inhibit ATP-stimulated PC secretion from alveolar type II cells to a greater extent than SP-A1 (6

82 Lung alveolar type II cells uniquely synthesize surfactant, a

83 fer in gene expression from their progenitor alveolar type II cells, we analyzed transcriptional regu

84 interactions of SP-A with phospholipids and alveolar type II cells were investigated using mutant fo

85 Epithelial alveolar type II cells were SP-A-positive, and Clara cel

86 s, in close proximity to fibroblast foci and alveolar type II cells, were observed in IPF lungs.

87 -binding protein, is abundantly expressed in alveolar type II cells where it plays a role in lung sur

88 d of a polarized monolayer of differentiated alveolar type II cells, which secreted surfactant into t

89 Treatment of primary cultures of adult alveolar type II cells with siRNA targeting Erm diminish