ライフサイエンスコーパス: amidino

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1 d with the specific protease inhibitor bis(5-amidino-2-benzimidazo-lyl)methane (BABIM) markedly atten

2 protease (dMCP)-3, i.e., aprotinin or bis(5-amidino-2-benzimidazolyl) methane (BABIM), did not.

3 dazolyl)methane ketone, and hemi-BABIM is (5-amidino-2-benzimidazolyl)(2-benzimidazolyl)methane), and

4 One such inhibitor is bis(5-amidino-2-benzimidazolyl)methane (BABIM), standing out a

5 n a manner similar to that reported by bis(5-amidino-2-benzimidazolyl)methane (BABIM).(1) Alternative

6 -benzimidazolyl)methane, keto-BABIM is bis(5-amidino-2-benzimidazolyl)methane ketone, and hemi-BABIM

7 a potential metalloprotease inhibitor, bis(5-amidino-2-benzimidazolyl)methane, and provide snapshots

8 , and -hemi-BABIM-Zn2+ (where BABIM is bis(5-amidino-2-benzimidazolyl)methane, keto-BABIM is bis(5-am

9 roadly acting pancreatic enzyme inhibitor (6-amidino-2-naphthyl p-guanidinobenzoate dimethanesulfate,

10 emic mixture of inhibitor FX-2212, (2RS)-(3'-amidino-3-biphenylyl)-5-(4-pyridylamino)pentanoic acid,

11 el series of fXa inhibitors incorporating an amidino 6,5-fused bicyclic moiety at the P1 position has

12 rence for linear aliphatic polyamines as the amidino acceptor substrate, especially for spermidine an

13 ng HAuCl4 with a CO2-responsive monomer N-(3-amidino)-aniline (NAAN).

14 sent a new CO2-responsive polymer, poly(N-(3-amidino)-aniline) (PNAAN), coated gold NPs (AuNPs) synth

15 r, unlike previously described guanidino- or amidino-based inhibitors which have pK(a) values greater

16 Several 5-guanidino- and 5-amidino-based oseltamivir derivatives were synthesized a

17 inobenzylidene)cycloheptanone, and 2,8-bis(4-amidino- benzylidene)cyclooctanone.

18 alent bond formation between the inhibitor's amidino carbon and the active-site Cys274, and solution

19 The amidino compounds L-N6-(1-iminoethyl)lysine, L-N5-(1-imi

20 Additionally, amidino derivative 3a (Cbz-l-Leu-l-Phe-CONH-d-CH[C(NH)NH

21 dom copolymer poly(dimethyl acrylamide-co-(N-amidino)ethyl acrylamide), or P(DMA-co-NAEAA), containin

22 inked to the positively charged guanidino or amidino functionalities.

23 s enhanced van der Waals interactions in the amidino furan-DNA complex.

24 creening dose of 10 micromol/kg, 4 of the 12 amidino furans described here are more active than the p

25 of creatine biosynthesis: the transfer of an amidino group from arginine to glycine to form ornithine

26 chemical moiety other than a guanidino or an amidino group.

27 lifetime is attributed to distortion of the amidino groups in this complex, resulting in less effici

28 rays contain 6-12 carboxylic acid groups, 12 amidino groups, 6 thiol groups, or 6 thiol groups and 6

29 The most promising compounds were (4-amidino)-L-phenylalanine-containing inhibitors, which re

30 Substitution of an alkyl group of the amidino nitrogen, except for in 9, 13, and 15, resulted

31 stem in the absence of a substitution of the amidino nitrogens resulted in higher affinity for DNA th

32 The amidino P1 residue D,L-(4-AmPhGly)P(OPh)2 was utilized i

33 to gp120 residues 421-431 with a C-terminal amidino phosphonate diester mimetic of the Lys(432)-Ala(

34 by formation of covalent adducts of a hapten amidino phosphonate diester was attributed to micro and

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