ライフサイエンスコーパス: amine group

1 he 4-substituent of the pyrroline ring is an amine group.

2 ation of Asn 95 in recognizing the substrate amine group.

3 25, which is in close proximity to the alpha-amine group.

4 ar general base catalysis by the neighboring amine group.

5 how evidence of an equatorially coordinating amine group.

6 cytotoxin (TCT) without affecting a critical amine group.

7 int chirality in the vicinity of a secondary amine group.

8 umber of methyl substituents on the terminal amine group.

9 termediate is intramolecularly trapped by an amine group.

10 -trans-retinal by drugs containing a primary amine group.

11 een the carboxyl group of 5caC and a primary amine group.

12 ing reaction to install an electron donating amine group.

13 rable to nucleophilic addition of a tethered amine group.

14 fying other analytes containing free primary amine groups.

15 wer than that of the compounds with tertiary amine groups.

16 :1 relationship between bound Au complex and amine groups.

17 pH-dependent due to the protonation of their amine groups.

18 drolysis and amidization of surface-tethered amine groups.

19 ctionalized polystyrene beads having pendant amine groups.

20 ditionally acylated the C4' hydroxyl and C3' amine groups.

21 ability of the amine and with the number of amine groups.

22 in films having varying densities of surface amine groups.

23 ccharide, which may be due to the absence of amine groups.

24 act as a bioisostere of hydroxyl, thiol, or amine groups.

25 H-bonding interactions between phosphate and amine groups.

26 as well as replacing the carboxylic acid and amine groups.

27 pling reagents and then reacted with protein amine groups.

28 -PS composite surfaces via their superficial amine groups.

29 n a single nanodrop solvates both protonated amine groups.

30 formation of urea linkages at the expense of amine groups.

31 , through reactions with its pendant primary amine groups.

32 ponent bearing either a terminal amide or an amine group (40%) revealed analogous trends.

33 Additionally, the incorporation of amine groups allows covalent coupling of the QDs to the

34 methylene-4-nitrostyrene from amine group to amine group along oligoethyleneimine tracks up to eight

35 has a His-brace in which the His-1 terminal amine group also coordinates to a copper.

36 ugh ionic interaction if its N17' protonated amine group (an "address") with a nonconserved acidic re

37 ration transfer effect (GluCEST) between its amine group and bulk water, with potential for in vivo i

38 is governed by interactions between specific amine groups and protein residues, and that this is not

39 -carbon chain triamine with terminal primary amine groups and replacement of the eighth methylene by

40 wn that apart from the nature and density of amine groups and the spatial separation of the acidic an

41 t pH 5.0 or 7.2 resulted in the oxidation of amine groups and, for collagen type II, the specific dec

42 9, with d9 indicating a deuterated trimethyl amine group) and meeting folate-intake recommendations.

43 identified as a mixture of nitro, imine, and amine groups, and following reduction, there was suffici

44 was covalently bound to agarose via terminal amine groups, and the variables examined were GAG concen

45 er solubility of drugs containing a tertiary amine group are reported.

46 s suggest that the interactions at the alpha-amine group are stronger for full agonists such as gluta

47 so suggest that in biological mixtures where amine groups are abundant, the trapping of EPO-generated

48 n pH at the surface of the particles as free amine groups are generated.

49 raamide complexes with four appended primary amine groups are measured as a function of pH.

50 ded conformation in which the two protonated amine groups are solvated by a single water nanodrop.

51 zeolite frameworks doped with methylene and amine groups are studied using density functional theory

52 These amine groups are then converted to corresponding N-diaze

53 ity, large surface area and high fraction of amine groups as aptamer binding sites.

54 s containing either a carboxylic group or an amine group at the C-3 position were synthesized and cov

55 zeolites can accommodate both methylene and amine groups at high concentrations with minimal strain.

56 mong the best substrates, whereas those with amine groups at the 5-position were poor substrates.

57 Analogues with cyclic basic amine groups attached via ethoxy linkages at the C-8 pos

58 g the concentration of carboxylic groups and amine groups before and after membrane modification with

59 similar to that of thiophenol, aniline, and amine groups but not as that of hydroxyl.

60 from a tertiary to a secondary to a primary amine group, but that solvent insertion dominates in all

61 ilon-SUK containing both carboxylic acid and amine groups can be either protonated or deprotonated de

62 eakly acidic silanol/aluminol with secondary amine groups can mimic proline catalysts and are more ef

63 ependent from pH 8 to pH 4 (the pK(a) of the amine group conjugate acid).

64 These data showed that the four amine groups contribute significantly to proton-catalyze

65 the strength of the interaction at the alpha-amine group correlates with the extent of cleft closure

66 The N-terminus primary amine group does not make a significant contribution to

67 Materials functionalized with amine groups dominate this field, largely because of the

68 Protonation of amine groups doubles the strength of hydrophobic interac

69 Within the secondary amine group, elevated adjusted odds ratios were observed

70 ed polyethylene glycol (PEG) film containing amine groups, followed by the self-assembly of gold nano

71 The Pcs were functionalized with an amine group for covalent conjugation purposes and were d

72 ed by using electrochemical technique and an amine group for immobilizing biomolecules; thus, it is i

73 d the necessity of hydroxy quinoline and the amine group for La(3+) ion binding and the glyco-moiety

74 by alternate solvation of the two protonated amine groups for clusters with up to 10 water molecules.

75 ion, there was sufficient amounts of primary amine groups for covalent attachment of a polyethylene g

76 Furthermore, the reported affinity of amine groups for semiconducting SWNTs, as opposed to the

77 nal theory simulations confirmed the role of amine groups for stabilizing key intermediates through h

78 L3), Leu267(7.32), and Ile274(7.39), and the amine group forms a hydrogen bond with the side chain of

79 Since the alpha-amine group forms bridging interactions at the cusp of t

80 in the presence or in the absence of primary amine group from aminophospholipids and amino acids.

81 ase activity is detected upon transfer of an amine group from an amino donor substrate to glyoxylate,

82 ffect that the degree of substitution of the amine group has on B-N bonding versus solvent insertion.

83 with different substitutions on the pendant amine groups have been synthesized (R = H (1), Me (2), a

84 alogues such as compound 13 containing basic amine groups have significantly increased PI3K inhibitor

85 s proton could be transferred to the leaving amine group, helping overcome a significant energy barri

86 ock copolymer bearing halogen bond-accepting amine groups, higher-order structures were obtained in b

87 After linking DNA to the amine groups, hybridization reactions with fluorescently

88 ses competitive hydrogen bonding between the amine groups (hydrogen-donor) and the phosphate/carbonyl

89 el 6-(difluoromethoxy)-2,5-dimethylpyridin-3-amine group in 19e contributed to the potency and improv

90 en-bonds between the phosphate group and the amine group in eggPE and LPE was observed with infrared

91 for late functional group conversion of a p-amine group in the peptides to the desired affinity labe

92 ected as rapid selective acylation of the 2'-amine group in two sequence contexts.

93 They attack amine groups in amino acids, peptides and proteins to fo

94 ffinity to the donor groups (COO(-) and some amine groups in its deprotonated form, NH2) of cysteine

95 Covalent modification of primary amine groups in multiply protonated or deprotonated poly

96 y TL) is a metabolite of Hcy and reacts with amine groups in proteins to form stable amides, homocyst

97 tive ligands on surfaces by diluting surface amine groups in self-assembled and cross-linked monolaye

98 r interactions of zwitterionic phosphate and amine groups in sphingosine-1 phosphate (S1P) to conserv

99 In the presence of dCO2, the amine groups in the chitosan get protonated to convert n

100 e of both alkyl tails in the outer shell and amine groups in the core/inner shell.

101 The ability to covalently modify primary amine groups in the gas phase with N-hydroxysuccinimide

102 rought about by acylation of surface-exposed amine groups in the initial step of the bioconjugation p

103 dity than MOF-5, a likely consequence of the amine groups in the structure, although, in contrast to

104 reasing gradually as the density of terminal amine groups increases as a function of generation.

105 Trp(9)) of the linear peptide: their charged amine groups interact with acidic residues from TM2 and

106 at it is carbamylated, since an unprotonated amine group is available to act as a Lewis base and form

107 Interestingly, although the amine group is buried in the hydrophobic core, the hydro

108 partial agonist kainate, in which the alpha-amine group is constrained in a pyrrolidine ring.

109 The amine group is found to substantially aid in the removal

110 rage parallel to the bilayer normal, and the amine group is oriented toward the headgroups of the lip

111 structure-selective chemical reaction at 2'-amine groups is a robust technology for interrogating lo

112 ogel) pH sensor based on covalently attached amine groups is described.

113 Finally, the availability of the surface amine groups is further demonstrated by their reaction w

114 This finding suggests that replacing an amine group (K side chain) with a primary amide group (Q

115 The Lys173 amine group lies just 6 A from the amine group of the co

116 functionalized with mixture of carboxyl and amine groups NDandante or amine NDamine, carboxyl NDvox

117 umidity, which facilitates formation of free amine groups needed for the initial reaction with dihydr

118 PS NP coated with primary amine groups (NH2) possessed positively charged surfaces

119 neither naphthalene-based modifiers without amine groups nor those with tertiary amine moieties are

120 hydrogenation catalysis, occurs through the amine group, not the aromatic ring as is widely believed

121 uggesting that 5MPCA modification by protein amine groups occurs in vivo.

122 formed between a free, unprotonated, primary amine group of a lysine side chain in the peptide and th

123 The protonated amine group of AdoMet could provide a proton via a water

124 an acetyltransferase that blocks the primary amine group of amino acids on charged tRNA molecules, th

125 surface via cation exchange and the cationic amine group of an adjacent molecule.

126 oup of bestatin, which mimics the N-terminal amine group of an incoming peptide, binds to Zn2 with a

127 Locating the central amine group of desmethoxyverapamil near the selectivity

128 n abstraction of a proton from the substrate amine group of dimethylglycine prior to C-H bond breakag

129 The simulations suggest that the amine group of GABA forms cation-pi interactions with Ty

130 red by conjugation to the free thiol and the amine group of gamma GSK, respectively, resulting in for

131 n H-bond between the N-3 of the 5'-C and the amine group of Gln-148.

132 ts was developed that react with the primary amine group of glycerophosphoethanolamine (PE) lipids to

133 carboxylate group of D23 and the side chain amine group of K28 that indicate salt bridge interaction

134 m, suggesting weak interactions at the alpha-amine group of kainate.

135 neral base to deprotonate either the epsilon-amine group of Lys-142 or to activate a water molecule a

136 e developed conditions to modify the epsilon-amine group of lysine in tryptic peptides with O-methyli

137 onventional antibody conjugation through the amine group of lysine or the thiol group of cysteine res

138 lic-acid group on SWNT-COOH and the terminal amine group of PA6.

139 he strength of the interactions at the alpha-amine group of the agonist with the protein in all but o

140 Additionally, the interactions at the alpha-amine group of the agonists have also been probed by stu

141 cal shifts, a pKa of 7.7 is measured for the amine group of the catalytic residue T1, confirming that

142 he Lys173 amine group lies just 6 A from the amine group of the conserved essential Lys92 side chain

143 Recent work suggests that the amine group of the GABA molecule may form a cation-pi bo

144 Our structures suggest that the amine group of the glmS ribozyme-bound coenzyme performs

145 nteraction of the protein with the aliphatic amine group of the ligand is very similar for the all of

146 or three (me3) methyl groups attached to the amine group of the lysine side chain.

147 ers an acyl chain from a phospholipid to the amine group of the N-terminal cysteine residue of the ap

148 s of the interactions between the N-terminus amine group of the peptide and several lipid atoms shows

149 substrate by hydrogen bonding to either the amine group of the peptide linkage or a backbone carbony

150 ity of a salt bridge between the sulfate and amine groups of 3-O-sulfoglucosamine is explored through

151 The interaction of both of the two amine groups of a diamine molecule with the sensor is es

152 ral different anionic species at the pyrrole amine groups of an oxoporphyrinogen unit within the supr

153 bonding between phospholipid head groups and amine groups of chitosan.

154 d C6 hydroxyl groups of alpha-mangostin with amine groups of different pKa values.

155 film by covalent bond formation between the amine groups of enzyme or NAD(+) and the carboxylic acid

156 the first direct NMR characterization of the amine groups of glucosamine and 3-O-sulfoglucosamine in

157 of the dendron derivatives to the peripheral amine groups of PAMAM followed by reduction.

158 imidate, which can form a covalent bond with amine groups of proteins.

159 icles together with the high affinity of the amine groups of the analyte for the nanoparticle surface

160 ylic groups of the 4-carboxyphenyl layer and amine groups of the antibody.

161 ps on the polymer and the positively charged amine groups of the drugs.

162 etween the carboxylic acid and an accessible amine groups of the functional molecule.

163 In the formed complex, the charged amine groups of the polycation mainly interact with DNA

164 The amine groups of the stationary phase determine the charg

165 l substrate, L,L-SDAP, by the absence of the amine group on the amino acid side chain.

166 of the band at 1529 nm, which is due to the amine group on the beads, or the increase of the amide b

167 We found that an amine group on the side chain of this residue is necessa

168 ted with the remaining primary and secondary amine groups on PEI to afford anionic functionalities.

169 ly 682+/-5 ns) dye was covalently coupled to amine groups on the 800 nm diameter silica spheres in or

170 n the carboxyl groups on the CNT surface and amine groups on the detection DNA probes.

171 Next, the amine groups on the graphene surface were activated usin

172 tion of carboxylic groups and an increase in amine groups on the membrane active layer, consistent wi

173 lable reagent, acetaldehyde-d4, to label the amine groups on the monoamines via reductive amination.

174 determined that the added steric bulk of the amine groups on the P2N2 ligands hinders catalysis and t

175 acetylene than ethylene while the functional amine groups on the pore/cage surfaces further enforce t

176 Hyaluronic acid is covalently linked to amine groups on the surface of these plates by 1-ethyl-3

177 formed by nucleophilic attack of either the amine group or the sulfhydryl group of the substrate on

178 ecule contact, including possible effects of amine group oxidation and molecular conformation.

179 (trans) of 2.6 and 3.1, and of the enalapril amine group, pK(cis) and pK(trans) of 5.9 and 5.6.

180 AMACE1 was coupled via its primary amine group (pKa 8.2) under aqueous conditions to four m

181 ffective antagonists had a partially charged amine group predicted to penetrate the channel pore, ant

182 In contrast, blocking free amine groups preexisting in the stroma with acetic anhyd

183 / N-hydroxysuccinimide (EDC/NHS) between the amine group present in the probe and carboxylic groups p

184 esidues present on the enzyme periphery with amine groups present on a novel redox polymer, poly[viny

185 ng hydrogen bonding between the carbonyl and amine groups present within the monolayer structure.

186 t His-225, in deprotonation of the substrate amine group prior to FAD reduction.

187 eared to prevent adhesion, whereas secondary amine groups promoted adhesion, in agreement with previo

188 n was exothermic, presumably because of DOPE amine group protonation.

189 At low pH, which protonates the LY97241 amine group, recovery from block at hyperpolarized poten

190 e-wide transcriptome analysis shows that the amine groups reduce the perturbations caused by GO on ce

191 ral to proton-coupled transport and that the amine group serves the same functional role as the Na2 i

192 In addition, computations indicate that the amine groups shift their pKa values due to the confined

193 nsubstituted willardiines with primary alpha-amine groups similar to that of the full agonist glutama

194 istribution in DPPE molecules shows that the amine groups strongly interact with the phosphate and ca

195 ased on polymers containing simple aliphatic amine groups substantially reduce the work function of c

196 containing a thiol, a thioether, or an extra amine group such as arginine, cysteine, lysine, methioni

197 hocking of the methane-rich mixture produced amine groups, suggesting the possible synthesis of amino

198 Binding of AuCl(4)(-) to amine groups tethered to the interior of a 2 nm siloxane

199 c compounds of environmental concern contain amine groups that are positively charged at environmenta

200 and direct methods to convert C-H bonds into amine groups that are prevalent in many commodity chemic

201 ic homo- and copolymers containing secondary amine groups that can be converted into nitric oxide (NO

202 a pocket of the appropriate size bordered by amine groups that could aid in the binding of DDT throug

203 ganic framework functionalized with tertiary amine groups that exhibits high capacities for radioacti

204 ael-retro-Michael reactions between adjacent amine groups that move it up and down the track.

205 substrates, producing a homogeneous layer of amine groups that serve as sites for DNA attachment.

206 ompounds with hydrocarbon ester and tertiary amine groups, the bulk polymer itself is elastomeric and

207 ate HAAs by N-hydroxylation of the exocyclic amine group; the resultant N-hydroxy-HAA metabolites for

208 o an intermediate bearing a fluorochrome and amine groups, then reacted with either HIV-Tat peptide o

209 n sponge effect" associated with multivalent amine groups, this class of ligand-exchanged QDs is able

210 Covalent binding via reaction of one amine group to a boron-doped, smooth Si-Cl substrate is

211 ation of alpha-methylene-4-nitrostyrene from amine group to amine group along oligoethyleneimine trac

212 The succinimide ester group reacts with the amine group to initiate antibody surface immobilization,

213 Intramolecular H transfer from the amine group to one of the two O atoms in the nitro group

214 c activation by N-oxidation of the exocyclic amine group to produce N-hydroxylated metabolites, which

215 provides a surface that readily reacts with amine groups to allow covalent immobilization of antibod

216 Inhibitors require at least two amine groups to be effective.

217 c alkylation of a polymeric scaffold bearing amine groups to give synzymes that catalyze the Kemp eli

218 ing agent, to convert polymer-bound tertiary amine groups to less chloramine-reactive quaternary ammo

219 inding and to a lowered pK(a) of a substrate amine group upon binding P450 2D6.

220 against S. pyogenes were conjugated to Ptyr amine group via biotin-NeutrAvidin coupling.

221 factors is transformation of a nitro into an amine group via reduction with a low-valent titanium in

222 g of the crowded substitution at the central amine group was found to be the reason for the presence

223 late via cleavage of a carbamate linkage, an amine group was left that provided an attachment site fo

224 er functionalization with multiple azide and amine groups was achieved without degradation of the ket

225 The hydroxyalkylammonium-(amine) group was introduced at the 5' position of the 2'

226 ted with vitamin B(6), which lacks a primary amine group, was variable at this pH.

227 inating in a reactive carboxylate, ester, or amine group were full, potent human A(3)AR agonists.

228 that two primary and at least one secondary amine group were required.

229 Different primary amine groups were found to be (potential) labeling sites

230 thalic acid) with 2-amino terephthalic acid, amine groups were incorporated into the framework to pro

231 OSCs with primary amine groups were reacted with isotopic formaldehydes to

232 When primary amine groups were reintroduced by azide-alkyne coupling,

233 onfirmed the surface modification of CNTs by amine groups, whereas dynamic light scattering establish

234 zed via click chemistry, and the other is an amine group which can also be functionalized by classic

235 e disulfide bridge and provided the terminal amine group, which facilitates addition of a cross-linke

236 The degree of site-isolation of the amine groups, which affect the material's catalytic prop

237 he stable and complete modification of these amine groups, which can be reversible upon the addition

238 o functionalize the treated surfaces to form amine groups, which were further activated with glutaral

239 relative position of the internal secondary amine group with respect to the terminal groups.

240 First, interaction of an inhibitor's amine group with the conserved active-site Asp is essent

241 Reaction of amine groups with activated esters would be catalyzed by

242 rom specific interactions of the amidine and amine groups with the active-site residues of trypsin an