ライフサイエンスコーパス: aminergic

1 ntification of some of these likely sites of aminergic action will allow for directed studies of thei

2 observed potencies of the effector lines in aminergic and cholinergic neurons assessed here may help

3 , pinpointing locations in the network where aminergic and neuropeptide signalling modulate synaptic

4 a new topological plan for understanding how aminergic and peptidergic modulation of behaviour is ach

5 ) of adult lobsters and crabs receives dense aminergic and peptidergic projections.

6 ronal networks are endogenously modulated by aminergic and peptidergic substances.

7 In comparison with the other aminergic and the cholinergic projection systems, which

8 he aminergic systems is similar, and several aminergic cells have locations and morphologies that str

9 at strongly suggest homology with identified aminergic cells in other crustaceans.

10 es that increase the presynaptic function of aminergic cells may provide neuroprotection in Parkinson

11 m LDCVs is critical for the function of some aminergic circuits.

12 gent potentiates the presynaptic function of aminergic circuits.

13 To identify new aminergic drugs in vivo, we used a mutation in the Droso

14 Descending aminergic fibers, revealed by antibodies to tyrosine hyd

15 ectivity for allosteric binding sites across aminergic G protein-coupled receptor.

16 Aminergic G protein-coupled receptors (GPCRs) have been

17 xtracellular domain was described at several aminergic G protein-coupled receptors, including muscari

18 e privileged structural motifs recognized by aminergic G protein-coupled receptors.

19 Applying this model to aminergic GPCR sequences, we first validate the general

20 inding site in the D2R and probably in other aminergic GPCRs as well.

21 sponding G-protein-coupled receptors (termed aminergic GPCRs) belong to the class of cell membrane re

22 e pharmacologically highly relevant class of aminergic GPCRs, we here present the development of cova

23 nanomolar affinity fluorescent probes for 14 aminergic GPCRs.

24 es, an observation with few precedents among aminergic GPCRs.

25 ns of these helices in different families of aminergic GPCRs.

26 of information regarding patterns of spinal aminergic innervation at early stages, when the fish are

27 Despite depletion of the aminergic innervation on the ipsilateral side, shock-ind

28 uence of the alterations in, and decline of, aminergic inputs to both autonomic and somatic spinal nu

29 Specificity of aminergic involvement was tested by using intra-PVH admi

30 2-null mice have lower-than-normal levels of aminergic metabolites and content.

31 Aminergic modulation of glycinergic transmission may thu

32 at C. elegans is a useful model to study the aminergic modulation of sensory-mediated locomotory beha

33 ining alpha6 subunits are typically found at aminergic nerve endings where they play important roles

34 and showed an endocytic deficit specific to aminergic nerve terminals.

35 known synergistic actions of NA with another aminergic neuromodulator, serotonin, and raise the possi

36 The proximity of Ebony-containing glia to aminergic neurons and genetic interaction results sugges

37 ter understanding of the functional roles of aminergic neurons and how they influence behavior.

38 We report the development of aminergic neurons from 0-10 days postfertilization (dpf)

39 of Lewy bodies, neurofibrillary tangles, and aminergic neurons in the locus ceruleus, dorsal raphe nu

40 i) footshock-induced activation of medullary aminergic neurons is a secondary consequence of stress,

41 (ii) stress-induced activation of medullary aminergic neurons is not necessarily predictive of an in

42 Alternatively, individual aminergic neurons might selectively modulate the animals

43 ial reduction of Fos expression in medullary aminergic neurons on the ipsilateral side.

44 Aminergic neurons that modulate the synapse may have ver

45 y expression of DVMAT in a single subtype of aminergic neurons, but required at least two systems, su

46 om SV to LDCV fractions was also enhanced in aminergic neurons.

47 mushroom body by differential contacts with aminergic neurons.

48 erve the relative trajectories of individual aminergic neurons.

49 ulation of rate-limiting enzymes involved in aminergic neurotransmitter production.

50 P2-dependent mechanism for the regulation of aminergic neurotransmitter synthesis contributing to uni

51 isease states associated with alterations in aminergic neurotransmitters, we investigated the contrib

52 Orexin neurons heavily innervate many aminergic nuclei that promote wakefulness and inhibit RE

53 n systems in goldfish barely innervate these aminergic populations related to the regulation of sleep

54 Our findings suggest that aminergic populations with descending processes are amon

55 ols this decision via top-down extrasynaptic aminergic potentiation of the primary osmosensory neuron

56 In summary, we postulate that aminergic presynaptic taste cells synthesize only 5-HT,

57 ism, rats bearing unilateral transections of aminergic projections were challenged with intravenous I

58 rograde labeling, that the sources of spinal aminergic reactivity include the posterior tuberculum (d

59 We find that each of the aminergic receptor genes is expressed in restricted regi

60 We also use aminergic receptor gfp reporter fusions as tools to visu

61 e the expression pattern of several of these aminergic receptors, including two serotonin receptors (

62 adaptive responses to reduced or eliminated aminergic signaling and will be useful to identify the u

63 Despite the importance of aminergic signaling for regulating locomotion and other

64 of animals carrying a null mutation for all aminergic signaling is sufficient to restore odor-tracki

65 ected the relative contribution of different aminergic signalling pathways to biological processes es

66 We found increased apoptosis in the three aminergic systems analyzed when compared with animals ma

67 Our results suggest that the major aminergic systems described in adults are in place short

68 Our previous study tracked the ontogeny of aminergic systems in zebrafish (Danio rerio).

69 evertheless, the general organization of the aminergic systems is similar, and several aminergic cell

70 this model will help determine how multiple aminergic systems may contribute to the regulation of ot

71 Our data indicate that aminergic systems may interact at all levels of the sens

72 AT activity in either individual or multiple aminergic systems, using transgenic rescue techniques.

73 nation of the potential synaptic contacts of aminergic systems.

74 fferences between, and evolution of biogenic aminergic systems.

75 hich are heavily biased toward "traditional" aminergic targets and commonly described as small lipoph

76 higher median property values than those for aminergic targets, such as monoamine transporters and GP

77 results begin to sort out how purinergic and aminergic transmitters function within the taste bud to