ライフサイエンスコーパス: amino acid sequence

1 andemly repeating units of a conserved seven-amino acid sequence.

2 which is determined by the protein's primary amino acid sequence.

3 by its energy landscape, are encoded in the amino acid sequence.

4 imensional structure is contained within its amino acid sequence.

5 ase behaviour of a protein is encoded in its amino acid sequence.

6 edicted Puf repeat number, organization, and amino acid sequence.

7 ontained multiple mutations that altered the amino acid sequence.

8 versity of the proteome without changing the amino acid sequence.

9 lysine epsilon-amino group within a specific amino acid sequence.

10 ilarity to HIV-1 gp120 despite divergence in amino acid sequence.

11 proteins from donkey milk and elucidated its amino acid sequence.

12 ts intrinsic instability originated from the amino acid sequence.

13 rotein has a low complexity and highly polar amino acid sequence.

14 e substrate protein and contains a conserved amino acid sequence.

15 phase behavior of an IDP is sensitive to its amino acid sequence.

16 a-helical bundles of peptides with a similar amino acid sequence.

17 nate recognition sites, while preserving the amino acid sequence.

18 ecular weight incongruent with the predicted amino acid sequence.

19 ophilic characteristics without changing the amino acid sequence.

20 by replacing 61 amino acids with a novel 91-amino-acid sequence.

21 ely, which differ solely in their N-terminal amino acid sequences.

22 well conserved despite overall divergence of amino acid sequences.

23 similar secondary structures and rearranged amino acid sequences.

24 ulate conservation scores for nucleotide and amino acid sequences.

25 proteins as well as dissimilarities in their amino acid sequences.

26 nsive to predict most native structures from amino acid sequences.

27 ional ensembles of IDPs are encoded by their amino acid sequences.

28 f which are interspersed with highly charged amino acid sequences.

29 ifferent enzyme kinetic profiles and primary amino acid sequences.

30 p41 membrane-proximal external region (MPER) amino acid sequences across HIV-1 clades and the ability

31 NPQ in plants, to explore how differences in amino acid sequence affect NPQ capacity and kinetics.

32 y-restricted presentation of a modified AIP1 amino acid sequence (AIP1S).

33 Through amino acid-sequence alignment of NADP(+)- and NAD(+)-pre

34 Amino acid sequence alignments between bVP24 and eVP24 a

35 Thus, rather than the amino acid sequence alone, the antigenic sites of parvov

36 ffect predictor (VEP) plugin, COCOS captures amino acid sequence alterations stemming from variants t

37 The only essential input is amino acid sequence, although available structural infor

38 efined by differences in donor-recipient HLA amino-acid sequence (amino-acid mismatch score, AMS; and

39 tand this specificity, we performed detailed amino acid sequence analyses and investigated the cataly

40 Through amino acid sequence analysis of S proteins of representa

41 Amino acid sequence analysis revealed that VviCCC shares

42 matography-MS/MS analysis and error-tolerant amino acid sequence analysis.

43 using local (free-energy profiles along the amino acid sequence and (13)C(alpha) chemical shifts) an

44 bitor enzyme kinetics (Km and IC50), (2) its amino acid sequence and (3) its ability to activate calc

45 e mRNA: the genetic code which specifies the amino acid sequence and a conserved "codon optimality co

46 To examine the relationship between amino acid sequence and aggregation propensity, we made

47 timal side-chain conformations from just its amino acid sequence and backbone structure.

48 ntitative relationship between an antibody's amino acid sequence and its antigen binding affinity.

49 Its amino acid sequence and position of the hydrophobic clus

50 The precise amino acid sequence and prenyl group define a combinator

51 species with respect to their similarity in amino acid sequence and protein fold in comparison to ca

52 chnologies, the relation between a peptide's amino acid sequence and S/N remains largely nonquantitat

53 mycobacteria are evolutionarily unrelated in amino acid sequence and three-dimensional structure to t

54 se the MAST output from six-frame translated amino acid sequences and filters for predefined biologic

55 formation-based analysis of the concatenated amino acid sequences and identified an extensive covaria

56 complementarity-determining region (CDR-L3) amino acid sequences and/or Vkappa,lambda-Jkappa,lambda

57 ve molecular mass of 50 kDa, as predicted by amino acid sequencing and mass analysis, confirming that

58 Differences in donor-recipient HLA amino-acid sequence and physicochemical properties enabl

59 ine learning to predict peptide S/N based on amino acid sequence, and identify specific physical prop

60 The primary nucleotide sequence, deduced amino acid sequence, and IgE-binding sites of Aed a 3 we

61 nary changes in pairs of positions along the amino acid sequence, and making inferences on structure

62 , often small in size, and highly diverse in amino acid sequence, and many require specific transitio

63 Biochemical characteristics, such as the PrP amino acid sequence, and posttranslational modifications

64 ing protein 1 (EB1) via a novel noncanonical amino acid sequence, and this GAR22beta-EB1 interaction

65 n all-atom 3D simulations of keratin primary amino acid sequences, and tyrosine phosphorylation predi

66 Repetitive nucleotide or amino acid sequences are often engineered into probes an

67 helix alpha6' in the interface make up of an amino acid sequence as E192'xxL195'xxR198'L199'xxL202'R2

68 diction of solubility that requires only the amino acid sequence as input.

69 alysis of larger biomolecules for confirming amino acid sequences, assessing sequence variants, and c

70 that comprises two repeats of a canonical 18 amino acid sequence associated with straight alpha-helic

71 n this region and it has been suggested that amino acid sequences associated with structural rigidity

72 pectrometry corroborated the deduced protein amino acid sequence at the protein level.

73 he CROP domain of TcdA centered on identical amino acid sequences at residues 2162-2189 and 2410-2437

74 ization signal (NLS) that was mapped to a 23-amino-acid sequence at the protein's C terminus.

75 udy was to improve the alignment between the amino acid sequences attached to the upper and lower aro

76 ied to cause polymorphism, but the intrinsic amino acid sequence basis for this polymorphism has been

77 Ten and 16 amino acid sequences, bearing a core of six and 12 rando

78 quenched fluorogenic peptide comprising the amino acid sequence between the thionin and the acidic d

79 At the level of entry, differences in the amino acid sequences between the human and mouse ortholo

80 mRNAs with changed codon bias have the same amino acid sequence but attain different conformations,

81 aring gene variants that encode an identical amino acid sequence but differ in their GC content and/o

82 that TPT recognition and binding depended on amino acid sequences but not on secondary, tertiary or q

83 actin are nearly indistinguishable in their amino acid sequence, but are encoded by different genes

84 The fold of a protein is encoded by its amino acid sequence, but how complex multimeric proteins

85 eins with little homology to any other known amino acid sequence, but which is composed of a primary

86 Cys-His-Asp-CONHL (where L = organic struts) amino acid sequences by covalently attaching them to the

87 y (MALDI-TOF) and the determination of their amino acid sequences by electrospray ionisation mass spe

88 'D3 domain through a relatively unstructured amino acid sequence, called here the N-terminal linker.

89 ied eukaryotes possess a tandemly repeated 7-amino-acid sequence, called the canonical CTD, which orc

90 accurate at determining whether an arbitrary amino acid sequence can be a protein.

91 riteria for determining whether an arbitrary amino acid sequence can be a protein.

92 Antibody amino-acid sequences can be numbered to identify equival

93 Amino acid sequence comparisons of the CPBs made by 8 ra

94 However, amino acid sequence comparisons show pervasive genomic m

95 sically disordered regions (IDRs) having low amino acid sequence complexity.

96 ces that are subject to GC usage and primary amino acid sequence constraints.

97 teraction surfaces, can accommodate numerous amino acid sequences containing basic and hydrophobic re

98 What kinds of amino acid sequences could possibly be protein sequences

99 assessment of HLA epitope antigenicity than amino acid sequence data alone, and it may allow predict

100 eins in the HSP-90 family that contained the amino acid sequence DDDDK identical to the carboxy-termi

101 ts evolved more rapidly than the rest of the amino acid sequence despite the selective pressure to ke

102 ges at the six positions in which the target amino acid sequence differed.

103 ctural similarities, despite sometimes large amino acid sequence differences.

104 or Machine model, whose feature set includes amino acid sequence, disorder propensity, and the rank o

105 Significant amino acid sequence divergence among these AID orthologs

106 key factor for the emergence of the striking amino acid sequence divergence observed between the micr

107 alpha-helices positioned in membranes; (iv) amino acid sequences, domain architecture, functional an

108 links messenger RNA nucleotide sequence with amino acid sequence during protein synthesis.

109 accurate alignments for both nucleotide and amino acid sequences, even on ultra-large datasets or da

110 he NCoR/SMRT complex, by removing almost all amino-acid sequences except the methyl-CpG binding and N

111 e tail needle N-terminal tip is built in the amino acid sequence, explaining its extraordinary conser

112 We discovered that amino acid sequence features of melanopsin protein contr

113 all accessions and are the most conserved in amino acid sequence for most accessions.

114 ugh the identification of an archaic-derived amino acid sequence for the collagen type X, alpha-1 (CO

115 The only required input to the server is an amino acid sequence for the target protein.

116 This editing alters the amino acid sequences for scores of proteins, including m

117 There are 20(200) possible amino-acid sequences for a 200-residue protein, of which

118 s revealed numerous polymorphisms in the RCA amino acid sequence from O. australiensis.

119 Deleting the 18 amino acid sequence from S2 -SLF1 stabilized the protein

120 riants (e.g., H3.3), which differ in primary amino acid sequence from their canonical counterparts, s

121 ple biophysical metrics of "developability." Amino acid sequences from 137 antibodies in advanced cli

122 o synthesize, isolate, and characterize many amino acid sequences from only a few precursors provides

123 ed of homodimeric beta subunits that contain amino acid sequences from the alpha subunit that confer

124 Therapeutic peptides are short amino acid sequences (generally considered <50 amino aci

125 EigenTHREADER takes a query amino acid sequence, generates a map of intra-residue co

126 omparison to Cdc42, but the function of this amino acid sequence has not been elucidated.

127 hin bioinformatics, the textual alignment of amino acid sequences has long dominated the determinatio

128 teins and in their functions, although their amino acid sequences have diverged significantly during

129 Given the high amino acid sequence homology between fish enzymes, a 3-D

130 code small proteins (LipA and LipB) that had amino acid sequence homology to bacterial adhesins and s

131 pical activator of Cdk1 and Cdk2 that has no amino acid sequence homology to cyclins, are sterile and

132 As a proof-of-concept, we used a 7 amino acids sequence (HSSKLQL) specific for Prostate Spe

133 fied an Mtb protein (PPE15) that showed weak amino acid sequence identities with mammalian perilipin-

134 Functional complementation correlates with amino acid sequence identity between orthologs, but vari

135 proteins also display extreme divergence in amino acid sequence identity between STs (i.e., 59%-61%

136 S1 is a SLAMF6 homolog with an amino acid sequence identity of 97% to SLAMF6 in its lig

137 Nevertheless, the maximum pairwise amino acid sequence identity with currently recognized f

138 tromere protein A (CENP-A), shares about 50% amino acid sequence identity with H3.

139 s ten genes coding for proteins sharing high amino acid sequence identity with members of the Ros/Muc

140 GFLOMT2 displayed the highest amino acid sequence identity with norlaudanosoline 6-OMT

141 use P. berghei ENT1 (PbENT1) shares only 60% amino acid sequence identity with PfENT1, we sought to c

142 BbdA shows low amino acid sequence identity with reported amidases and

143 er of this toxin family, sharing only 30-40% amino acid sequence identity with the others.

144 Even though both proteins share about 90% amino acid sequence identity, they exhibit different ope

145 deficiency viruses (HIV), tend to share high amino acid sequence identity.

146 51 genes, CYP51A and CYP51B, which share 59% amino acid sequence identity.

147 last Mini-RNase III-like enzymes sharing 75% amino acid sequence identity.

148 ntain two closely-related paralogs with >75% amino acid sequence identity.

149 in domain organization they display just 31% amino acid sequence identity.

150 ntain the DCCL-conserved motif but share low amino acid sequence identity.

151 The encoded proteins share ~85% amino acid sequence identity.

152 w are to show that, despite their simplified amino acid sequences, IDPs/IDPRs are complex entities of

153 We show that amino acid sequences immediately downstream of a substra

154 ctin initiates retrograde transport and that amino acid sequences implicated in macrolide toxin bindi

155 n-26S proteasome pathway, and identify an 18 amino acid sequence in the C-terminal region of S2 -SLF1

156 n at multiple sites along the spectrin-betaV amino acid sequence in the lineage leading to mammals, t

157 s of decoy peptides derived from the primary amino acid sequence in the SOD2-binding site in hsp70.

158 rphisms resulting in alternative or aberrant amino acid sequences in 1,084 genes in the 129-strain ge

159 WPV1 amino acid sequences in neutralizing epitopes varied fro

160 This peptidic natural product exhibited an amino acid sequence including several beta-alanines that

161 ibody sequencing protocols, 100% of antibody amino acid sequences, including identity of Leu and Ile

162 critical residues in APs, show that certain amino acid sequences induce very strong translational ar

163 ients express the entire Factor VIII (FVIII)-amino-acid sequence intracellularly as 2 non-secreted po

164 peptides and proteins, in which a peptide's amino acid sequence is inferred directly from the precur

165 These results show that a limited amino acid sequence is responsible for SCH-C specificity

166 rate of synthesis are linked to a protein's amino acid sequence is still not well defined.

167 e show that when the collection of arbitrary amino acid sequences is viewed in an appropriate geometr

168 the intricate relationship among a protein's amino acid sequence, its cotranslational nascent-chain e

169 Binding of UBA5 to UFM1 is mediated via an amino acid sequence, known as the UFM1-interacting seque

170 pendence of the polypeptide retention on the amino acid sequence length with R(2) > 0.99 and allows i

171 data provide new evidence demonstrating that amino acid sequence Leu(480)-Gln(481): 1) is crucial for

172 ha2M* requires ligation of the GRP78 primary amino acid sequence (Leu(98)-Leu(115)).

173 thologous proteins that have diverged at the amino acid sequence level in a way that is likely to imp

174 ehalogenases that are distinguishable at the amino acid sequence level, implying different modes of e

175 a, have rapidly diverged in evolution at the amino acid sequence level.

176 son of CCR5 and CCR2b identified a divergent amino acid sequence located at the junction of transmemb

177 eft within Rb accommodates peptides with the amino acid sequence LXCXE.

178 of interest to short, highly representative amino acid sequences ("markers") and (ii) a search step

179 odern methods employ the alignment of DNA or amino acid sequences, mostly not genome-wide but only on

180 lix of HLA class I alleles, corresponding to amino acid sequence motif 77 to 83, produced clustering

181 biochemical functions, defined by conserved amino acid sequence motifs, be embedded into a structura

182 these functions is mediated primarily by two amino acid sequence motifs, ITAMs (immunoreceptor tyrosi

183 f serological reactivity better than Bw4/Bw6 amino acid sequence motifs.

184 not occur at random, neither in terms of the amino acid sequences nor through random splicing of pept

185 The amino acid sequence of a protein affects both its struct

186 The amino acid sequence of a protein is the blueprint from w

187 The genetic code, which defines the amino acid sequence of a protein, also contains informat

188 ne, a method that predicts, from the primary amino acid sequence of a protein, which amino acids are

189 are nucleotide substitutions that alter the amino acid sequence of a protein.

190 The amino acid sequence of AtxA1 is identical to that of Atx

191 The amino acid sequence of DAIP contains 5 potential glutami

192 The C-terminal 15-amino acid sequence of K2 is remarkably conserved across

193 The amino acid sequence of medin is strikingly similar to th

194 The amino acid sequence of PrP varies among species, and thi

195 We show that the entire amino acid sequence of R5 interacts with silica during s

196 The amino acid sequence of SpvD is highly conserved across d

197 ined its nucleotide sequence, as well as the amino acid sequence of the AMA1 protein.

198 action demonstrate that rearrangement of an amino acid sequence of the AMP resulted in identical ove

199 Thus, the amino acid sequence of the arginine patch can predict th

200 yringe delivery, it is also dependent on the amino acid sequence of the multidomain peptide.

201 nificantly in Podoviridae, unexpectedly, the amino acid sequence of the N-terminal tip is exceptional

202 a particular gate represented by a specific amino acid sequence of the oestrogen receptor (ER).

203 The amino acid sequence of the peptide from bovine adrenal g

204 dentify the aggregation-prone regions of the amino acid sequence of the PID and engineer a highly sol

205 ensemble, which in turn, depend on the exact amino acid sequence of the protein.

206 of protein biogenesis beyond specifying the amino acid sequence of the protein.

207 The amino acid sequence of the RBS naturally varies across a

208 y determined primarily by differences in the amino acid sequence of the various IgG subclasses and by

209 in, stemming from differences in the primary amino acid sequence of the various subclasses, as well a

210 Although the amino acid sequences of CLEC18A, CLEC18B, and CLEC18C ar

211 hyl labeled peptides to identify and confirm amino acid sequences of di/tripeptides that are separate

212 ms are associated with the similarity of the amino acid sequences of domains II and III of the toxins

213 The amino acid sequences of farnesyl diphosphate synthase (F

214 thetases with high similarities to consensus amino acid sequences of human protein-serine/threonine k

215 of intrinsic disorder propensity within the amino acid sequences of insulin analogues that may provi

216 Unlike the case with ubiquitin, the amino acid sequences of ISG15s from various species are

217 In this study, the amino acid sequences of Japanese quail and northern bobw

218 The amino acid sequences of S. aureus PSMs are well conserve

219 to the FPs of influenza and HIV, the primary amino acid sequences of the FPs of beta-CoVs in 3 differ

220 n this study, we determined the location and amino acid sequences of the FPs of S glycoproteins of 3

221 Four differences in the corresponding amino acid sequences of the M-Tha and M-SAD are shown to

222 Although the amino acid sequences of these two pFPs differed signific

223 Amino acid sequences of those peptides were determined u

224 Analysis of amino acid sequences of three bZIPs does not identify in

225 Due to early evolutionary divergence, the amino acid sequences of trypanosome splicing factors exh

226 Amino acid sequencing of isolated amyloid protein identi

227 stricted CD8(+) T-cell epitopes from the 693-amino-acid sequence of the VP13/14 protein.

228 We identified the amino acid sequence on VP4 and its cholangiocyte binding

229 hat conformational restraints imposed by the amino-acid sequence on the transition states determine t

230 to form a single extended sheet, followed by amino acid sequence optimization at the newly formed str

231 Naturally selected amino-acid sequences or experimentally derived ones are

232 Changes of amino acid sequences outside the Lys(87)-Leu(122) centra

233 Here, we show a four-amino-acid sequence (Phe-Cys-Pro-Phe), which we call the

234 cJHEH) was characterized in terms of deduced amino acid sequence, phylogeny, homology modeling and do

235 However, amino acid sequence plasticity relative to subunit expre

236 eins; however, asymmetric dimers with shared amino acid sequence present a unique challenge for HDX b

237 utations at up to 53 residues (18%) of their amino acid sequence, primarily distributed across the DN

238 dimensional structure of proteins from their amino acid sequences remains a challenging problem in mo

239 Accurate prediction of amyloid-forming amino acid sequences remains an important challenge.

240 rther analyses revealed that Csk1 lacks a 20-amino-acid sequence required for its budding yeast count

241 Combined with our finding that the protein amino acid sequence resembles previously described mollu

242 truncation and fragmentation of the primary amino-acid sequence result in shorter or cleaved polypep

243 Bioinformatic analysis of the IQGAP1 amino acid sequence revealed potential cleavage sites fo

244 is to nonidentical, but highly similar, CDR3 amino acid sequences revealed a number of other TT-relat

245 Substance P (SP) [SP + 3H](3+) ion (SP(3+); amino acid sequence RPKPQQFFGLM-NH2).

246 -known levels of protein structure: primary (amino acid sequence), secondary (helices, sheets and tur

247 exosite for fXa in prothrombinase within the amino acid sequence Ser(478)-Val(479)-Leu(480)-Gln(481)-

248 t not other IL-1R family members, exhibit an amino acid sequence similar to binding site A of human a

249 ssembled de novo, and contigs with predicted amino acid sequence similarities to viruses in the nonre

250 rolases are clustered into families based on amino acid sequence similarities, and belonging to a par

251 , bioinformatics analysis of MIP showed some amino acid sequence similarity to human FK506-binding pr

252 Although FLNb shows high amino acid sequence similarity with FLNa, we reveal that

253 rM and eukaryotic subfamilies based on their amino-acid sequence similarity.

254 Fixed changes in amino acid sequence, such as A82V in the EBOV glycoprote

255 Based on their amino acid sequence, tapirins are specific to these extr

256 sion of synaptotagmin-2, which lacks a seven amino acid sequence that contains the phosphorylation si

257 esulting IL12Rbeta1 proteins have an altered amino acid sequence that could not be predicted on the b

258 ries of short peptides were used to identify amino acid sequences that affect the efficiency of this

259 1 to mitotic chromosomes requires C-terminal amino acid sequences that are similar to mitotic chromos

260 r immune responses, the persistence of viral amino acid sequences that are the major targets of cellu

261 ctions require high affinity for nonspecific amino acid sequences that are ubiquitous in proteins.

262 of this relationship is the total number of amino acid sequences that can fold to a target protein s

263 Analysis of identical CDR3 amino acid sequences that were shared by individuals in

264 fference is given relative to the unmodified amino acid sequence), that easily can be mistaken for th

265 which allows the facile modification of the amino acid sequence, the introduction of unnatural amino

266 timizing the cyclization linker, length, and amino acid sequence, the tightest cyclic peptide achieve

267 Amino acid sequencing then showed that this effect invol

268 mini of these orthologs are not conserved in amino acid sequence, they inhibit activity and become au

269 Based on 866 different amino acid sequences this protein is divided into three

270 f dimers are generated by threading a target amino acid sequence through several structural templates

271 ion at the level of both gene expression and amino acid sequence, thus resulting in differences in le

272 ladder sequence of the y-ions, allowing the amino acid sequence to be deduced from a single-stage ma

273 d by codon optimization and by modifying the amino acid sequence to be identical to that of an early

274 odon optimization and by modifying the RSV F amino acid sequence to conform to that of an early passa

275 We slightly modified amino acid sequences to evaluate peptide sequence proper

276 al amino acids and engineered site-selective amino acid sequences to preserve both activity and struc

277 ttempted site-specific reversion of hSH3BGRL amino-acid sequence to mSH3BGRL and found V108A substitu

278 A protocol for mapping amino-acid sequences to coarse-grained beads enables the

279 nd near-perfect libraries where the ratio of amino-acid sequences to nucleic-acid sequences approache

280 Comparison of rodent and human FLAP amino acid sequences together with an analysis of a publ

281 measured by the same group and with the same amino-acid sequence used for structure determination, pr

282 fined by their nucleotide, rather than their amino acid sequence, using targeted editing of the mouse

283 We hypothesized that regions of amino acid sequence variability may contain signal motif

284 ps structural aspects of prions (such as PrP amino acid sequence variants and PrP conformational stat

285 Amino acid sequence variants of the prion protein (PrP)

286 he retroviral Gag protein exhibits extensive amino acid sequence variation overall; however, one regi

287 stiffness of the PA scaffolds, dependent on amino acid sequence, was found to determine the macrosco

288 ibrils containing point substitutions in the amino acid sequence, we also show that charged residues

289 were isolated and their molecular masses and amino acid sequences were determined using ESI-MS and ES

290 ypusine, with minimal dependence on flanking amino acid sequences, were identified.

291 predict secondary-structure populations from amino acid sequences, which simultaneously characterizes

292 are predicted to encode proteins with unique amino acid sequences, which would allow them to be speci

293 ependent degradation signal resides in an 11-amino-acid sequence, which is not only sufficient but al

294 report that sAnk1 shares homology in its TM amino acid sequence with sarcolipin, a small protein inh

295 These proteins share no amino acid sequences with known cellular or viral protei

296 ll help toward the ultimate goal of designed amino-acid sequences with made-to-measure folding mechan

297 nce from peppermint with a plastid targeting amino acid sequence, with or without a gene for biosynth

298 trains, and this phenomenon was dependent on amino acid sequences within the viral ligand UL18.

299 lculate the energy of the structure given an amino acid sequence, without knowledge of the final, des

300 As with modern biology, amino acid sequence would have been a primary determinan