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1 rying a 37-amino-acid deletion within the gK amino terminus.
2 ciently than sulfopeptides based on the CCR5 amino terminus.
3 ore extended and shifted toward the collagen amino terminus.
4 er face of the core shell, distinct from the amino terminus.
5 rbors a second transmembrane domain near its amino terminus.
6 atypical site for glycosylation (NXC) in its amino terminus.
7 ctive AT(12) is linked to protonation of the amino terminus.
8 catalyzed removal of 6 amino acids from the amino terminus.
9 moving approximately 30 amino acids from the amino terminus.
10 of an 11-residue tail that is located at the amino terminus.
11 S is a dimeric protein with a domain-swapped amino terminus.
12 dual topology after deletion of most of the amino terminus.
13 verlapping motifs for these functions in the amino terminus.
14 f its zinc finger domain with the histone H3 amino terminus.
15 and requires conserved serines in the HDAC7 amino terminus.
16 d receptor (rKOR) with a FLAG epitope at the amino terminus.
17 oth muscle isoform of MYOCD, which lacks the amino terminus.
18 o the endoplasmic reticulum (ER) through its amino terminus.
19 xyl terminus and docking within the receptor amino terminus.
20 generated sulfopeptide mimetics of the CCR5 amino terminus.
21 ining a plastid transit peptide (PTP) at its amino terminus.
22 proline-rich 15-amino-acid sequence near the amino-terminus.
23 primary cilium through dual acylation of the amino-terminus.
24 zinc atom, both hallmarks of the typical MCM amino-terminus.
26 mutation, we found that the cardiac-specific amino terminus acted in an autoinhibitory fashion to bin
28 required for the presentation of the mature amino terminus (alpha-domain) of IcsA on the bacterial s
29 te a specific interaction between the 20 kDa amino terminus and 65 kDa carboxy terminus, after proteo
31 helix and an irregular loop at the conserved amino terminus and a shorter alpha-helix at the carboxy
32 ic protein that contains a TRIM motif at the amino terminus and a SPRY motif at the carboxyl terminus
33 ndent phospholipid binding C2 domains at the amino terminus and a VWA domain at the carboxyl terminus
34 tative chloroplast-targeting sequence in its amino terminus and also domains common to P-loop ATPases
36 both isoforms possess a unique 56-amino acid amino terminus and exhibit similar yet distinct enzymati
37 ess to the binding pocket is occluded by the amino terminus and extracellular loops of the receptor.
39 of the protein: Cys2 and Cys6 thiolates, the amino terminus and imidazole side chain of His1, and a p
40 perturbations are primarily localized in the amino terminus and in a highly conserved loop between re
41 tinct regions within SVT, one located in the amino terminus and one in the carboxy terminus, can inde
42 onstrate that AtCPK5 is myristoylated at its amino terminus and that myristoylation is required for m
43 tease that processes IcsA between the mature amino terminus and the beta-barrel outer membrane anchor
44 t interacts with the ATP-binding site at its amino terminus and with the substrate/inhibitor-binding
45 on of the cluster, which is located near the amino terminus and within the beta-barrel, through its a
46 extensive region of Vif spanning most of its amino terminus and zinc finger region, and cullin 5 (Cul
47 ed by K382 acetylation, which depends on the amino terminus, and is required for recruitment of selec
51 ained in the presence of a His(6) tag at the amino terminus, as compared with a His(6) tag at the car
52 actions between this salt and the protonated amino terminus, as well as corresponding changes in the
54 ylate EBNA1 at multiple sites throughout its amino terminus but not in the carboxy-terminal DNA bindi
55 hen compared with those with the full-length amino terminus, but how this is achieved remains unknown
58 at the juxtamembrane region of the receptor amino terminus contained the site of labeling for the po
59 MW-E) isoforms that lack a portion of the EL amino-terminus containing a nuclear localization sequenc
60 mrZ forms oligomers in solution but that the amino terminus, containing an unordered region and a bet
65 l DNA indicated that the absence of the UL84 amino terminus does not notably affect viral DNA synthes
66 e for IrtAB in iron import and show that the amino terminus domain of IrtA is a flavin-adenine dinucl
67 f these, termed Slack-A channels, contain an amino-terminus domain closely resembling that of another
68 nt of specific residues within the Galpha i1 amino terminus during receptor-mediated G i activation h
69 city for lysines only within the tetraspanin amino terminus even in the presence of other cytosolic l
70 constructs including the calcitonin receptor amino terminus exhibited responses to any of these ligan
71 MEC-4 chimeras to identify specific domains (amino terminus, first transmembrane domain, and extracel
72 lnD nitrogen sensor protein truncated at its amino terminus, fixes nitrogen in symbiosis with alfalfa
73 anonical RNA recognition THUMP domain at the amino terminus, followed by a gamma-class Rossmann fold
74 clononane-1,4,7-triacetic acid (NOTA) at the amino terminus, followed by a Gly-Ser-Gly (GSG) spacer.
77 FMRP, and a mutant (R138Q) that disrupts the amino terminus function, containing an integral tandem A
82 wever, a virus expressing E3L deleted of the amino terminus has reduced pathogenicity in an animal mo
83 s been documented for over a decade that the amino terminus has the ability to bind RNA despite havin
84 TNT2, to determine whether misfolding in the amino terminus (ie, PAD exposure) occurs in non-AD tauop
85 sults are consistent with a role for the HCS amino terminus in biotin acceptor substrate recognition.
86 igomerization, and suggest a role of the Wnt amino terminus in evasion of oxidizing inactivation.
87 To further characterize the role of the GRK2 amino terminus in receptor interaction and phosphorylati
88 scovered that other ABC transporters with an amino terminus in the ER had similarly configured conser
89 cts, the position of NSCaTE on the channel's amino terminus indicates that CaM can bridge the amino t
95 s, an HSV mutant devoid of gamma134.5 or its amino terminus is crippled for viral growth and release.
98 keletal and smooth muscle MLCK; however, the amino terminus is quite unique, without significant homo
100 the AAA region of MCM-helicases; the typical amino-terminus is missing and is replaced by a segment w
102 context, indicating the possibility that the amino terminus may directly contact Arg805 or that the d
103 jirovecii major surface glycoprotein: MsgA (amino terminus), MsgB (middle portion) and MsgC1 (carbox
104 firmly establish that only the extracellular amino terminus (Nout) copy of MRAP, oriented with critic
105 oclonal antibodies directed against the CCR5 amino terminus (NT) and extracellular loops, and CCR5 po
107 have shown that charge substitutions in the amino terminus of a chimeric connexin, Cx32*43E1, which
109 ss of reverting mutations were mapped to the amino terminus of a replicase subunit, nonstructural pro
110 ions suggest that changing 4 residues in the amino terminus of A3B not only retargets the protein fro
112 ivity of this mutant, demonstrating that the amino terminus of AAG is not strictly required for this
114 We find that location of cysteine at the amino terminus of an alpha-helix, associated with activi
116 nce spectroscopy show that the extracellular amino terminus of C99 includes a surface-embedded "N-hel
119 by a novel Ca2+/CaM-binding site within the amino terminus of channels (NSCaTE, for N-terminal spati
121 proteins, of Ca(2+)-dependent binding of the amino terminus of CNGA3 specifically to the carboxyl ter
123 cells have shown that phosphorylation of the amino terminus of DAT is required for AMPH-induced DA ef
127 th in mice and in MEFs and that in MEFs, the amino terminus of E3L functions to inhibit the PKR pathw
130 Cys(2) predominantly labeled residues in the amino terminus of ECL2 and ECL3 (relative labeling inten
131 ed that while all regions except the extreme amino terminus of ExbD were indispensable for function,
132 erogeneity of signal peptide cleavage at the amino terminus of FGF2, whereas IGF1 displayed homogeneo
133 sor interacts with the amphipathic helix and amino terminus of functional Tha4 under conditions leadi
134 equired for FV capsid egress from cells; the amino terminus of FV Gag contains a cytoplasmic targetin
137 his work demonstrates that the myristoylated amino terminus of Galpha il proteins undergoes receptor-
138 cterized activation-dependent changes in the amino terminus of Galpha proteins in solution, but chang
139 CD11(+) DCs, the mutant virus that lacks the amino terminus of gamma134.5 undergoes temporal replicat
141 inus of HSV-1 glycoprotein B (gB) and in the amino terminus of gK cause extensive virus-induced cell
142 d extracellular cysteine residues within the amino terminus of gK contributed to the regulation of HS
144 gK carrying in-frame deletions spanning the amino terminus of gK immediately after the gK signal seq
146 ollectively, these results indicate that the amino terminus of gK is functionally and physically asso
147 rus-induced cell fusion, indicating that the amino terminus of gK is required for gB-mediated virus-i
150 well-defined beta-sheet structure within the amino terminus of gK, which is conserved among alphaherp
151 teines for the structure and function of the amino terminus of gK.IMPORTANCE We have previously ident
153 , we propose a mechanism whereby the extreme amino terminus of GRK2 forms an intramolecular interacti
154 (CaM) binding to a specific site within the amino terminus of GRK5 and this interaction occurs after
155 ine present in a conserved sequence near the amino terminus of GSK-3 generates an auto-inhibitory pep
157 osome induces a conformational change in the amino terminus of histone H4 that promotes interactions
158 substitution of threonine 30, located at the amino terminus of hNET with alanine (T30A-hNET), abolish
161 These results suggest a model in which the amino terminus of IrtA functions to couple iron transpor
162 hromatin-binding motif (CBM) situated at the amino terminus of LANA that is capable of binding direct
163 release of the membrane lytic region at the amino terminus of mature VI, allowing it to lyse the end
166 anti-HIV-1 function when transferred to the amino terminus of MX1, and that this fusion protein reta
167 s indicated an 11-amino acid deletion in the amino terminus of N. munroi CA1a relative to the C3 and
171 -repeats within the intrinsically disordered amino terminus of NP1 are required for splicing of the c
172 shown that the ubiquitin-like domain at the amino terminus of nsp3 is essential and participates in
173 lly encode a fusion protein that retains the amino terminus of NUP98; in this context, it is importan
174 have shown that a triple serine motif in the amino terminus of Olig2 is phosphorylated in cycling neu
175 acter capsulatus identified a residue in the amino terminus of one subunit (Ala(47)) that compensated
176 R mutant virus containing stop codons at the amino terminus of ORF2 does not reactivate from latency
177 a mutant virus containing stop codons at the amino terminus of ORF2 does not reactivate from latency
178 An LR mutant virus with stop codons at the amino terminus of ORF2 does not reactivate from latency
179 m (ER) retention/retrieval signal within the amino terminus of p12(I) is necessary for trafficking to
181 g the carboxy terminus of perilipin 1 to the amino terminus of perilipins 2 or 3 stabilize ABHD5 and
182 taining the switch I domain of RhoA, and the amino terminus of PKGIalpha (residues 1-59), which inclu
186 PKD1L2) remarkable for a large extracellular amino terminus of putative cell adhesion domains and a G
187 DNA binding by the evolutionarily conserved amino terminus of Rad52 is needed for the capture of the
188 with chimeric gL proteins that contained the amino terminus of Rh gL, although they retained their ab
189 strated via a direct interaction between the amino terminus of RhoA (residues 1-44), containing the s
195 initiation depends on 14 amino acids at the amino terminus of seipin, deletion of which results in f
196 es demonstrated that the SH(2) domain at the amino terminus of sequestosome 1/p62 interacts with IRS-
197 , PAS domains are commonly positioned at the amino terminus of signaling proteins such as sensor hist
199 presence of the polyglycine stretch near the amino terminus of TbpB contributes significantly to tran
200 neutralization experiments suggest that the amino terminus of TcdB interacts with the B2' region and
202 ortance of the juxtamembranous region of the amino terminus of the Family B calcitonin receptor for a
203 An LR mutant virus with stop codons at the amino terminus of the first open reading frame (ORF) in
204 An LR mutant virus with stop codons at the amino terminus of the first open reading frame (ORF) in
205 An LR mutant virus with stop codons at the amino terminus of the first open reading frame (ORF) in
206 l structure-based analyses indicate that the amino terminus of the GHV NS5A protein may serve a zinc-
207 pite recent solution of the structure of the amino terminus of the GLP1 receptor and several close fa
210 to its receptor, now bringing ECL3 above the amino terminus of the ligand and revealing possible char
213 ed that both serine 20 and serine 227 at the amino terminus of the protein are putative sites for pho
214 located the collagen binding activity to the amino terminus of the protein corresponding to amino aci
215 a 3(10) helix in the tail that projects the amino terminus of the protein deep into the minor groove
217 with CIITA, targeting serine residues in the amino terminus of the protein, including serine 288.
218 hanges are alterations involving the extreme amino terminus of the protein, known as the phosphatase-
219 e detected in the protease domain and in the amino terminus of the protein, which was previously prop
223 25 probes labeled residues within the distal amino terminus of the receptor, whereas the position 24
224 -directed mutagenesis studies identified the amino terminus of the RevA protein as being required for
225 ally those with a side chain that mimics the amino terminus of the stem peptide precursor to the bact
232 nnected through seven lysine residues or the amino terminus of ubiquitin, thereby allowing the assemb
234 us containing a FLAG epitope inserted at the amino terminus of UL29 expressed a tagged approximately
235 sum, deletion of the sequences encoding the amino terminus of UL84 affects interaction with UL44 and
239 1, was utilized to track the location of the amino terminus of VP1 in the 135S and 80S states of poli
240 provides a conserved molecular platform, the amino terminus of which interacts with the cryptic Polo
241 es bind the peptide only when present at the amino-terminus of a carrier protein and even conservativ
242 tified a novel highly conserved motif at the amino-terminus of Act1, which is critical for binding to
243 onserved Ras association (RA1) domain at the amino-terminus of AF6 as the minimal region sufficient f
245 y is to elucidate the mechanism by which the amino-terminus of APC contributes to the enhancement of
247 strate that protein-specific residues in the amino-terminus of FlaA and FlaB dictate export efficienc
249 nd 14-3-3 protein binding of the cytoplasmic amino-terminus of iRhom2 alter its interaction with matu
250 dentify a ubiquitin interaction motif at the amino-terminus of Jarid2, and demonstrate that this doma
253 ing this approach, a chimera composed of the amino-terminus of Rem and the core/carboxyl-terminus of
254 terminus of the light chain is linked to the amino-terminus of the heavy chain, was described to pote
255 site (log K = 11.0 +/- 0.3 at pH 7.4) at the amino-terminus of the peptide as well as a high affinity
256 ically inactive dSpCas9 protein fused to the amino-terminus of the transposase enzyme designed to tar
257 Consistent with differential effects of the amino terminus on the K259R mutation, we found that the
260 uding the presence of a structurally ordered amino terminus positioned within the active site and in
261 he US28 extracellular vestibule, whereas its amino terminus projects into the central core of US28.
263 nase in vitro and that myristoylation at its amino terminus promotes association with the plasma memb
267 lso no empirical data to orient the receptor amino terminus relative to the core helical bundle domai
269 ues in the LIN-35 Rb spacer domain and FZR-1 amino terminus, resembling inactivating phosphorylations
273 atoms from two histidine side chains and the amino terminus, similar to the endogenous copper coordin
275 several serine phosphorylation sites in the amino terminus that contribute to the regulation of cell
276 peats, but Dia2 also has a TPR domain at its amino terminus that interacts with the Ctf4 and Mrc1 sub
279 protein and a 243-amino acid sequence at the amino terminus that was unique to the N. crassa DGAT2 pr
280 r-binding domain) and a region closer to the amino-terminus that collectively could completely determ
281 cretion system contain a sequence within the amino-terminus that directs their export from the bacter
282 f an additional protein domain to either the amino terminus, the carboxy terminus, or to both termini
283 idual Wnt3a secretion/activity, those in the amino terminus, the thumb, and at the tip of the index f
284 oop and the tyrosine sulfate-containing CCR5 amino terminus, thereby reducing assembly of complexes t
286 ining unnatural N-methylated residues in the amino terminus to investigate whether the polypeptide ma
289 d Saccharomyces cerevisiae COX2 fused at the amino terminus to various alternative mitochondrial targ
290 ore, the virus expressing E3L deleted of the amino terminus was also IFN resistant in PKR(-/-) MEFs.
291 ity of a virus expressing E3L deleted of the amino terminus was fully rescued in type I IFN receptor
293 is constitutively phosphorylated within its amino terminus, whereas phosphorylation within the hinge
294 ) transforming element module on the channel amino terminus, whereas the C-lobe binds an EF-hand regi
295 ll capsid proteins bind to capsids via their amino terminus, whereas the carboxy terminus is unstruct
296 e predicted to harbor a FLYWCH domain in the amino terminus, which displays a WRKY-GCM1 fold characte
297 era mutagenesis, we demonstrate that the VP2 amino terminus, which forms a decameric, internal hub un
298 xonal ER of Luman's transcriptionally active amino terminus, which is transported to the cell body in
300 anges detected at several residues along the amino terminus (with no significant effect on the rate o
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