ライフサイエンスコーパス: amino-terminal

1 chimeric gene coding for the soybean native amino-terminal 86 amino acids fused to an insensitive sh

2 The amino-terminal 91-amino-acid domain of human MX2 confers

3 eric MX1/2 proteins, we demonstrate that the amino-terminal 91-amino-acid domain of MX2 confers full

4 nanometer diameter ovoid structures with 2-3 amino-terminal Abeta antibody binding sites, distinct fr

5 tides starting at residue Arg(5) as the main amino-terminal Abeta variants produced in the presence o

6 we found that ASF1 physically interacts with amino-terminal acetylated histones H3 and H4 and with ac

7 NatE complex can be a major contributor for amino-terminal acetylation at the ribosome exit tunnel.

8 Amino-terminal acetylation is a critical co-translationa

9 Amino-terminal acetylation is a ubiquitous modification

10 Amino-terminal acetylation is among the most ubiquitous

11 There are six known eukaryotic amino-terminal acetyltransferases (NATs), which are diff

12 eins in a eukaryotic cell carried out by six amino-terminal acetyltransferases (NATs).

13 ce, that being the addition of a 100-residue amino-terminal affinity purification tag.

14 e large, 140-250-kilodalton enzymes, with an amino-terminal alpha-helical region and a carboxy-termin

15 branes, which is mediated exclusively by the amino-terminal ALPS motif.

16 acetyl group to the alpha-amino group of the amino-terminal amino acid of proteins, which causes the

17 r data support a stepwise model in which the amino-terminal amphipathic helix of GTP-bound Sar1 stabl

18 ociated with the cytoplasmic membrane by its amino-terminal amphipathic helix.

19 el assay for the separation and detection of amino-terminal amyloid-beta (Abeta) peptide variants by

20 that lies within the combined properties of amino terminal and transactivation domains.

21 e determined sites of phosphorylation in the amino-terminal and carboxy-terminal domains that are pos

22 tion is mediated by sequences located in the amino-terminal and central domains of Hipk2 and the amin

23 X-ray crystal structures for the soluble amino-terminal and ligand-binding domains of glutamate r

24 nstrating extensive interactions between the amino-terminal and ligand-binding domains.

25 s large conformational rearrangements of the amino-terminal and ligand-binding domains.

26 The 5'-exon is held between the Prp8 amino-terminal and linker domains, and base-pairs with U

27 res of actin complexes with the unstructured amino-terminal and the leucine-rich repeat carboxy-termi

28 t nonglycosylated XXT2 lacking its cytosolic amino-terminal and transmembrane domain displays high ca

29 actions among cytoplasmic domains, including amino-terminal ankyrin repeats.

30 e-like N() with a disordered solvent-exposed amino-terminal beta-strand.

31 ve small-molecule inhibitors that target the amino-terminal bromodomains of BRD4, have been shown to

32 t transgenic mice to explore the role of the amino-terminal (BubR1(N)) and internal (BubR1(I)) Cdc20-

33 he 'small' and 'large' SRs contain a compact amino-terminal catalytic domain, but differ conspicuousl

34 Bub3 promotes binding of BubR1's conserved, amino terminal Cdc20 binding domain to a site in Cdc20 t

35 of FGF2, whereas IGF1 displayed homogeneous amino-terminal cleavage with complete removal of the bom

36 ses, thereby affecting Wnt solubility by its amino-terminal cleavage.

37 otiomyceta, has an unusual structure with an amino-terminal coiled-coil and a carboxy-terminal zinc b

38 her analysis of conserved amino acids in the amino-terminal conserved domain revealed that the tyrosi

39 We demonstrated that the amino-terminal conserved domain was essential for Arabid

40 We have investigated the influence of the amino terminal copper and nickel binding (ATCUN) motif o

41 We report here the amino terminal crystal structures of wild-type FMRP, and

42 protein interactions can occur through their amino-terminal CTS region.

43 nteraction between ORF31 and ORF24, (ii) the amino-terminal cysteine-rich and carboxyl-terminal basic

44 MAR autoantibodies was localized within the amino-terminal cytoplasmic domain of TRPM1.

45 These membrane proteins consist of an amino-terminal cytosolic domain involved in protein inte

46 of Burkitt's lymphomas, aggregate within an amino-terminal degron important for proteasomal destruct

47 We identified two HSV-1 ICP27 amino-terminal deletion mutants with a similar release d

48 Amino-terminal deletions of PGD2 fusions with a free C t

49 ide bond formation A (DsbA) proteins and the amino-terminal dimerization domain of macrophage infecti

50 ICP55 is unusual, as it involves breaking an amino-terminal diserine that is not known as an ICP55 su

51 chemoreceptor channel TRPA1 via formation of amino-terminal disulphide bonds, which results in sustai

52 DNA-binding/dimerization domain of Z and the amino-terminal DNA-binding domain of Pax5.

53 cocrystallization of this molecule with the amino terminal domain (ATD) of the hmGlu2 receptor prote

54 g through the entire molecule composed of an amino terminal domain (ATD), a ligand-binding domain (LB

55 a negative charge substitution (N2E) in the amino terminal domain allow unequivocal separation of th

56 ing cross-over between the twofold symmetric amino terminal domain and a twofold symmetric ligand bin

57 From fits of the amino terminal domain and LBD domains into the density m

58 s of activity that reside between the GluN2C amino terminal domain and the GluN2C agonist binding dom

59 , binds at the interface of the GluN1/GluN2B amino terminal domain dimer by an induced-fit mechanism.

60 udies have added S1PR2 as a receptor for the amino terminal domain of Nogo-A, and have demonstrated s

61 how allosteric inhibitors, acting within the amino terminal domain, further stabilize the LBD layer.

62 However, the amino terminal domain, transmembrane, and cytoplasmic re

63 KSHV-infected cells, which binds through its amino terminal domain.

64 n constructs have revealed the importance of amino-terminal domain (46-290) for memory suppression wh

65 receptor (AR) is recruited by ELK1, via its amino-terminal domain (A/B), as a transcriptional co-act

66 uN2A-GluN2D chimeric subunits implicates the amino-terminal domain (ATD) as a strong determinant of a

67 The amino-terminal domain (ATD) of AMPA receptors (AMPARs) a

68 olutionarily distinct structural domains: an amino-terminal domain (ATD), a ligand-binding domain (LB

69 ain (LBD) and structural rearrangement of an amino-terminal domain (ATD).

70 t binds to an extracellular domain called an amino-terminal domain (ATD).

71 , PrP(Sc) We examined the role of the PrP(c) amino-terminal domain (N-terminal domain [NTD], amino ac

72 r with each protomer containing an L30e-like amino-terminal domain (NTD) and a SPOUT methyltransferas

73 re clearly define the roles of the HTLV-1 CA amino-terminal domain (NTD) and CA CTD in particle bioge

74 a methionine residue at the junction of the amino-terminal domain (NTD) and the carboxy-terminal dom

75 HIV-1 capsid protein contains an amino-terminal domain (NTD) comprising seven alpha-helic

76 Furthermore, the GluN1 amino-terminal domain adopts a more open conformation wh

77 , uncharged linker between the lethal factor amino-terminal domain and diphtheria toxin A chain exped

78 e processing of N-glycosylation sites in the amino-terminal domain and downstream linker region.

79 ermine, an allosteric potentiator, opens the amino-terminal domain cleft of both the GluN2B subunit a

80 The amino-terminal domain contains four CXXXC sequence repea

81 and binding of allosteric modulators to the amino-terminal domain determine the open probability of

82 We show how Cbln1 hexamers "anchor" GluD2 amino-terminal domain dimers to monomeric beta-NRX1.

83 -associated protein and demonstrate that its amino-terminal domain disengages p53 from Numb, triggeri

84 rmore, the Arabidopsis HDR contains an extra amino-terminal domain following the transit peptide that

85 spectroscopy that the Escherichia coli NusG amino-terminal domain forms a complex with the acidic re

86 d and twisted fashion through interdigitated amino-terminal domain interactions, form a kinked centra

87 anine-rich kinase (SPAK) binding site in the amino-terminal domain is conserved.

88 One protein that binds Rb1 through the amino-terminal domain is encoded by Thoc1, a required co

89 The FliG amino-terminal domain is organized in a regular array wi

90 Indeed, when this amino-terminal domain is removed, the protein is retaine

91 binds to m(6)A-containing mRNA, whereas the amino-terminal domain is responsible for the localizatio

92 The unusually long amino-terminal domain of 550 residues that precedes the

93 edicted to code for a protein containing the amino-terminal domain of DNAJB1, a homolog of the molecu

94 ne-distal immunoglobulin-variable (IgV)-like amino-terminal domain of each is crucial to these intera

95 The amino-terminal domain of ExsA (NTD) is thought to mediat

96 different ORF34 domains interacted with the amino-terminal domain of HIF-1alpha.

97 Additionally, we demonstrate that the amino-terminal domain of human and bank vole PrP(c)s req

98 o may recognize the helical structure of the amino-terminal domain of Izumo1.

99 We find that an amino-terminal domain of PCM1 can restore ciliogenesis a

100 Snu114 and the amino-terminal domain of Prp8 position U5 snRNA to inser

101 ate by hydrogen bonding to a tyrosine in the amino-terminal domain of Prp8.

102 wn assays and showed that hsp70 binds to the amino-terminal domain of SOD2.

103 e use budding yeast to show that a conserved amino-terminal domain of the Dpb2 subunit of Pol epsilon

104 in CHO cells, we show that the cleft of the amino-terminal domain of the GluN2B subunit, which has a

105 The HIV-1 matrix (MA) protein is the amino-terminal domain of the HIV-1 precursor Gag (Pr55Ga

106 The very amino-terminal domain of the huntingtin protein is direc

107 We show that CIQ does not bind to the amino-terminal domain of the NMDA receptor and does not

108 We demonstrate that the amino-terminal domain of the normal prion protein, PrP(c

109 tive activity mediated by the ligand-mimetic amino-terminal domain of the receptor.

110 its located two regions in the extracellular amino-terminal domain of the subunit: the E loop (a loop

111 The amino-terminal domain of the VEEV capsid protein contain

112 The entire amino-terminal domain of VEEV capsid protein was found t

113 a more extensive set of interactions in the amino-terminal domain plays some role in the actions of

114 nteraction and cell-to-cell movement and the amino-terminal domain required for importin-alpha intera

115 tization is accompanied by disruption of the amino-terminal domain tetramer in AMPA, but not kainate,

116 ydrogenase domain, but rather depends on the amino-terminal domain that recruits PXDLS containing tar

117 DNA binding protein that binds via its small amino-terminal domain to high affinity arm-type DNA site

118 In a proposed model for AMPAR assembly, the amino-terminal domain underlies the formation of a dimer

119 In this study, the HTLV-1 capsid amino-terminal domain was found to provide distinct cont

120 The amino-terminal domain with a fold distinct among known T

121 These data suggest that interactions of the amino-terminal domain with the rest of the PrP(c) molecu

122 These domains, together with the amino-terminal domain, constitute a network of superheli

123 chinery depends on the integrity of both the amino-terminal domain, containing a number of putative R

124 y bioinformatics and mutagenesis in the TGB1 amino-terminal domain.

125 be an essential triple-arginine motif in the amino-terminal domain.

126 mainly contributed by the residues from the amino-terminal domain.

127 nded domain and papain-like proteases by its amino-terminal domain.

128 resolve the crystal structure of ACF7's NT (amino-terminal) domain, which mediates F-actin interacti

129 the interface of the ligand binding and the amino terminal domains in a homology model of GluN1/GluN

130 Cocrystallization of 14a with the amino terminal domains of hmGlu2 and hmGlu3 combined wit

131 e demonstrate that peptides corresponding to amino terminal domains VI and V of netrin-1 repel migrat

132 employing recombinant human mGlu2/3 receptor amino terminal domains, molecular modeling, and site-dir

133 In the absence of Ro, the GluN2A and GluN2B amino-terminal domains (ATDs) adopt "closed" and "open"

134 itive homo- and hetero-dimerization of their amino-terminal domains (ATDs) is a key step controlling

135 and 349-402 for synaptic suppression, while amino-terminal domains including NLS1 are dispensable.

136 r the suppression of axonal branching, while amino-terminal domains including NLS1 are dispensable.

137 elical bundle, directly interacting with the amino-terminal domains of adjacent subunits.

138 udied high-affinity interactions between the amino-terminal domains of GluA2 and GluA3 AMPA receptors

139 rovided a platform for further dissection of amino-terminal domains of nsp3.

140 C1ql2 and C1ql3 specifically bound the amino-terminal domains of postsynaptic GluK2 and GluK4 K

141 -RAG2 heterotetramer is 'Y-shaped', with the amino-terminal domains of the two RAG1 chains forming an

142 dence that the inherent conformations of the amino-terminal domains vary based on the subunit and mat

143 of isolated water-soluble ligand-binding and amino-terminal domains, as well as solving the first cry

144 COP9 signalosome, eIF3) or MPN (Mpr1, Pad1, amino-terminal) domains constitute the structural core o

145 Interestingly, deleting the amino-terminal EF-hands activates proteolysis prematurel

146 ned in frame with a CPD (YARKARRQARR) at the amino-terminal end and hexahistidine at the carboxy-term

147 in the carboxyl-terminal end of ECL2 and the amino-terminal end of ECL3, and Cys(10)-sec not efficien

148 d by abnormal polyglutamine expansion in the amino-terminal end of the huntingtin protein (Htt) and c

149 h ligands, the crystal structure of the Flfl amino-terminal EVH1 domain bound to a CENP-C peptide rev

150 Activation of PKR required the amino-terminal EVH1 domain of Dcp1a.

151 was found for 8 mutations distributed among amino terminal, exonuclease and catalytic domains.

152 One paralog of each protein contains an amino-terminal extension that targets proteins to mitoch

153 phorylation sites to the otherwise divergent amino-terminal extensions on these pollen sPPases.

154 ructural studies have been restricted to the amino-terminal extracellular domain, providing little un

155 peptide hormones, has been restricted to the amino-terminal extracellular domain, thus providing litt

156 depends on interactions taking place at the amino-terminal (FERM) and carboxyl-terminal (FAT) domain

157 receptor protomers, extracellular domain and amino terminal fragment (NTF), and the 7TM or C-terminal

158 Further, when an amino-terminal fragment (Met(1)-Arg(33)) of the N170K/K2

159 tify a prostate apoptosis response-4 (Par-4) amino-terminal fragment (PAF) that is released by divers

160 se-11 cleaves gasdermin D, and the resulting amino-terminal fragment promotes both pyroptosis and NLR

161 Ligation of uPAR with the amino-terminal fragment recruited alpha5beta1 integrin a

162 with the urokinase receptor binding domain (amino-terminal fragment) leads to enhanced migration of

163 Within the amino-terminal fragment, a functional J domain is necess

164 g simulations, evidenced that both chain and amino terminal function characterized by higher hydrophi

165 previously characterized viruses expressing amino-terminal fusions, this virus expresses more VP26 f

166 e coexpression of fluorescent protein-tagged amino-terminal Golgi-targeting sequences (cytoplasmic-tr

167 lasmic reticulum when they were expressed as amino-terminal green fluorescent protein fusions in toba

168 feoB encodes an 83-kDa protein with an amino-terminal GTPase domain and a carboxy-terminal doma

169 40-60 amino acid residues each, spanning the amino-terminal half of Erb1.

170 of CI (cylindrical inclusion) and P3N-PIPO (amino-terminal half of P3 fused to Pretty Interesting Po

171 ving two helicase modules, of which only the amino-terminal helicase domain appears to be catalytical

172 hat a mutant form of human Dicer lacking the amino-terminal helicase domain can process double-strand

173 An amino-terminal helix from each of two subunits of the ca

174 An amino-terminal helix location underpins the covalent lin

175 , cytoplasmic amino and carboxyl termini, an amino-terminal helix, and conserved extracellular cystei

176 due to changes in the amphipathicity of the amino-terminal helix, suggesting that membrane associati

177 In contrast, removal of the amino-terminal hydrophilic SPX domain does not affect th

178 a conserved PtdSer binding pocket within the amino-terminal IgV domain.

179 HopQ binds the amino-terminal IgV-like domain of human CEACAM1, CEACAM3

180 PECAM-1 homophilic interactions, mediated by amino-terminal immunoglobulin homology domain 1, contrib

181 ophilic-binding domain, which is composed of amino-terminal immunoglobulin homology domains 1 and 2 (

182 interactions, known to be mediated by its 2 amino-terminal immunoglobulin homology domains, are esse

183 actor), which is in complex with JIP1 (C-Jun-amino-terminal-interacting protein 1) and JNK.

184 BA-KEN-ABBA motifs, and association with the amino-terminal KEN box required to form the MCC.

185 al Akt/NO synthase activation, reduced c-Jun amino terminal kinase phosphorylation, and decreased oxi

186 We further show that c-Jun amino-terminal kinase (JNK) plays a pivotal role in medi

187 The c-Jun amino-terminal kinase (JNK) plays a role in inflammation

188 Here we demonstrate that c-Jun amino-terminal kinase (JNK) signaling is crucial for ger

189 A construct lacking the amino-terminal leader and transmembrane domain caused cy

190 The amino-terminal ligand binding domain of SIRPalpha is hig

191 An amino-terminal linker within FAK is essential for its bi

192 n human LAMB2 cluster in or near the laminin amino-terminal (LN) domain, a domain required for extrac

193 By contrast, interaction with the amino-terminal longin domain conferred specificity on VA

194 plicating distal effects of the carboxyl- on amino-terminal membrane binding.

195 ophobic amino acids, which projects from the amino-terminal membrane-binding domain.

196 es such as serine; NatE requires a substrate amino-terminal methionine residue for activity.

197 of both FGF2 and IGF1, suggesting that FGF2 amino-terminal microheterogeneity does not alter mitogen

198 n the unstructured linker region joining the amino-terminal microtubule interacting and trafficking d

199 proteins as truncated forms showed that the amino-terminal modular low-density lipoprotein receptor

200 This binding also triggers exposure of an amino-terminal myristate moiety, which anchors Gag to th

201 In the circulation, alpha2AP undergoes both amino terminal (N-terminal) and carboxyl terminal (C-ter

202 uding the highly conserved membrane-proximal amino-terminal (N-terminal) region, is distinct from oth

203 ecies, directly interacts with the cytosolic amino terminal (NT) domain of the yeast Golgi V-ATPase a

204 e Factor transcription factors (ERFVIIs) via amino-terminal (Nt-) cysteine [1, 2].

205 The amino-terminal nucleotide binding domain rotates to clos

206 ntaining point mutations or deletions in the amino-terminal or the carboxy-terminal regions of the E

207 We show here that amino-terminal p53 (ATp53) mutations often result in the

208 as well as a chimeric protein containing the amino-terminal part of AtCGL160 and Synechocystis sp. PC

209 erminal and central domains of Hipk2 and the amino-terminal part of C/EBPbeta.

210 CTX)) and bone formation (procollagen type I amino-terminal peptide (PINP)) were estimated using Cox

211 Monitoring of amino-terminal peptides showed that Arabidopsis ICP55 wa

212 tains a carboxyl-terminal beta-barrel and an amino-terminal periplasmic module composed of five polyp

213 ase domain from the inhibitory action of the amino-terminal photosensory portion of the photoreceptor

214 tiana tabacum) pollen tubes, SEC3a displayed amino-terminal Pleckstrin homology-like domain (SEC3a-N)

215 ical of leucine-rich repeat proteins with an amino-terminal pocket that presumably binds acylated lig

216 t huntingtin protein (mHTT) with an expanded amino-terminal polyglutamine (poly(Q)) stretch.

217 in, we present the solution structure of the amino-terminal portion of mouse HOP2, which contains a t

218 We propose that the amino-terminal portion of p33 is unstructured when VacA

219 ustered missense mutations were found at the amino-terminal portion of the delta subunit of guanine n

220 Using 5 synthetic peptides that spanned the amino-terminal portion of the hMPV N protein, we identif

221 ing FrmR(E64H) reveals that an FrmR-specific amino-terminal Pro(2) is proximal to Cys(35), and these

222 To determine whether an amino-terminal pro-B-type natriuretic peptide (NT-proBNP

223 Combined measurement of soluble ST2 and amino-terminal pro-B-type natriuretic peptide at 12 hour

224 e combination of results for soluble ST2 and amino-terminal pro-B-type natriuretic peptide provides e

225 The combination of soluble ST2 and amino-terminal pro-B-type natriuretic peptide showed exc

226 lue of serial measurement of soluble ST2 and amino-terminal pro-B-type natriuretic peptide to clinica

227 ers elevated (soluble ST2, >/= 500 ng/mL and amino-terminal pro-B-type natriuretic peptide, >/= 4,500

228 pe NP (BNP) level of 250 pg/mL or less or an amino-terminal pro-brain-type NP (NT-proBNP) decrease of

229 Advanced cardiac stage III patients (amino-terminal pro-natriuretic peptide type B >8500 ng/L

230 hemoconcentration, weight loss, reduction in amino terminal, pro B-type natriuretic peptide, increase

231 t of high-sensitivity C-reactive protein and amino-terminal probrain natriuretic peptide is debated.

232 , apolipoprotein B/apolipoprotein A-1 ratio, amino-terminal probrain natriuretic peptide, high-sensit

233 ssense point mutation in the procollagen III amino terminal propeptide segment (PIIINP) of collagen,

234 the first exercise bout for determination of amino-terminal propeptide of collagen I content.

235 elatin 1 h before exercise showed double the amino-terminal propeptide of collagen I in their blood,

236 in the noncollagenous carboxyl-terminal and amino-terminal propeptides.

237 mains, but genetic evidence suggests that an amino-terminal protein interaction domain is also import

238 JAK2 induced the phosphoactivation of c-Jun amino-terminal protein kinase (JNK) and the downstream t

239 Upon dsDNA engagement, the AIM2 amino-terminal pyrin domain (PYD) is responsible for dow

240 sitide 3-kinases (PI3Ks), interacting via an amino-terminal RAS-binding domain (RBD).

241 as proSAAS (named after four residues in the amino terminal region) has many attractive properties.

242 le metabolites (most likely depending on the amino-terminal region around the highly conserved cystei

243 The amino-terminal region contains an eag domain, which is c

244 The amino-terminal region forms a tight dimerization domain

245 These results indicate that the amino-terminal region of HDAg is in close contact with t

246 ere pS denotes phosphoserine) located in the amino-terminal region of HopQ1.

247 etiological missense variants cluster in the amino-terminal region of human BCL11A, and we demonstrat

248 We show that the amino-terminal region of JAZ10.4 contains a cryptic MYC2

249 An amino-terminal region of LifA shares homology with the c

250 We determined that the amino-terminal region of SidE was essential for SidJ-med

251 tion that links the activity of SidJ and the amino-terminal region of SidE, which is required to modu

252 otal of six SN-HPCs for mutations within the amino-terminal region of the gene CTNNB1 (cadherin-assoc

253 er caused by polyglutamine expansions in the amino-terminal region of the huntingtin (Htt) protein.

254 hat MLO homooligomerization, mediated by the amino-terminal region of the protein, and carboxyl-termi

255 mutation affecting structural aspects of the amino-terminal region of the protein, and support the co

256 Wnt inhibitors that act by cleaving the Wnt amino-terminal region to inactivate specific Wnt ligands

257 roach showed that replacement of the pre-TM1 amino-terminal region with the corresponding P2X2 recept

258 the carboxyl-terminal region) and Dact1 (the amino-terminal region).

259 old, consistent with the hypothesis that the amino-terminal region, disordered in the crystal structu

260 irectly with the plasma membrane through its amino-terminal region.

261 ent modification of cysteine residues in the amino-terminal region.

262 ized in plant cells is located in the MAN2B1 amino-terminal region.

263 s observed for HLA peptides derived from the amino terminal regions of the proteins, suggesting that

264 Amino-terminal regions of secretin-family peptides conta

265 pha-amino group of a number of nonmethionine amino-terminal residue substrates such as serine; NatE r

266 on whereas carboxyl domain (598-854) and the amino-terminal residues (1-45) including the nuclear loc

267 ncated form, termed tAlv-a1-pHCl, lacking 37 amino-terminal residues that precede the N-terminal heli

268 in-ligases, characterized by the presence of amino-terminal RING (really interesting new gene) and PH

269 The protein contains one amino-terminal RNA recognition motif (RRM) known to bind

270 Measles virus (MeV) N features an amino-terminal RNA-binding core and a 125-residue tail d

271 membrane localization of PBS1 is mediated by amino-terminal S-acylation.

272 H1 gene encodes a two-domain protein with an amino-terminal Sec14-like phosphatidylinositol transfer

273 exchange, with the exception of the unfolded amino-terminal segments of the Aalpha and Bbeta chains e

274 This required the amino-terminal sequence of CAII, a region that binds oth

275 BPalpha, a related C/EBP family member whose amino-terminal sequences differ significantly from that

276 iates translation from codon 1, possesses an amino-terminal signal sequence, and is a type one integr

277 mitochondrial proteins are synthesized with amino-terminal signal sequences.

278 und that Ptenl(-/-) mice, which lack the NH2-amino terminal splice variant of PTEN, were unable to er

279 findings demonstrate that the occurrence of amino-terminal structural homogeneity may be associated

280 capsid-specific protease domain and the very amino-terminal subdomain are also involved in interactio

281 Our new data demonstrate that the very amino-terminal subdomain of Venezuelan equine encephalit

282 of different capsid-specific domains and its amino-terminal subdomains in viral particle formation.

283 The sensitivity to amino-terminal substitution was specific for DAT, becaus

284 l sequence, outer membrane localization, and amino-terminal surface exposure.

285 ate that CENP-B directly binds both CENP-A's amino-terminal tail and CENP-C, a key nucleator of kinet

286 distributed over several residues within the amino-terminal tail of the proximal histone.

287 anslational addition of methyl groups to the amino terminal tails of histone proteins regulates cellu

288 Histone amino-terminal tails (N-tails) are required for cellular

289 We show that the amino-terminal tails of the catalytic subunit of Pol alp

290 s characterized into 3 distinct domains: the amino terminal, the tandem repeat, and the carboxyl term

291 while DNA intimately contacts the downstream amino-terminal tier of the MCM motor ring.

292 ctional inactivation, their relevance in the amino-terminal transactivation domain is unclear.

293 RDs (UT-69, UT-155, and (R)-UT-155) bind the amino-terminal transcriptional activation domain AF-1, w

294 trations of the full-length EIIA(Glc) and an amino-terminal truncation mutant differ by 60-fold, cons

295 duced response, GIRK phosphorylation at this amino terminal tyrosine residue (Y12) enhances channel d

296 ound that the N-nsp3 interaction maps to the amino-terminal ubiquitin-like domain of nsp3, which is e

297 like lectins that recognize sialoglycans via amino-terminal V-set domains.

298 of this new study demonstrate that the very amino-terminal VEEV capsid-specific subdomain SD1 is a c

299 l-terminal yellow fluorescent protein-SlGGB1/amino-terminal yellow fluorescent protein-Gbeta heterodi

300 The amino-terminal zinc (N) finger of GATA1 critically contr