ライフサイエンスコーパス: aminoadipate

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1 amate transport was not inhibited by L-alpha-aminoadipate.

2 L-alpha-Aminoadipate (1 mM) inhibited uptake by only 25 +/- 4%.

3 We now report that L-alpha-aminoadipate also blocks or reverses the persistent depo

4 cal to glutamine transaminase K (GTK), alpha-aminoadipate aminotransferase, and mitochondrial asparta

5 d converts two plant endogenous amino acids, aminoadipate and tryptophan, to their respective N-acety

6 esis of lysine, enzymatic reduction of alpha-aminoadipate at C6 to the semialdehyde, requires two gen

7 at exposure of hippocampal slices to L-alpha-aminoadipate blocks or reverses quisqualate sensitizatio

8 Moreover, the pipecolate catabolite alpha-aminoadipate decreased 30-fold in RNA interference plant

9 ADPH) to the free enzyme followed by L-alpha-aminoadipate-delta-semialdehyde ( L-AASA) which adds in

10 .1.10] catalyzes the condensation of l-alpha-aminoadipate-delta-semialdehyde (AASA) with l-glutamate

11 LKR, and subsequently to glutamate and alpha-aminoadipate-delta-semialdehyde by SDH.

12 mM-1 min-1) at 16% the efficiency of L-alpha-aminoadipate in [32P]PPi/ATP exchange assays.

13 ism of the selective gliotoxicity of L-alpha-aminoadipate (L-alpha AA) is thought to involve its entr

14 ein S6:glutamate ligase and a putative alpha-aminoadipate ligase, defining the first group of ATP-gra

15 nal neurons and photoreceptor cells by alpha-aminoadipate or glutamate signaling.

16 phylogenetic comparisons show that the alpha-aminoadipate pathway enzyme is an outgroup to all aconit

17 yzes one of the regulated steps of the alpha-aminoadipate pathway for lysine biosynthesis in fungi.

18 The alpha-aminoadipate pathway for lysine biosynthesis is present

19 s catalyze hydrolyase reactions in the alpha-aminoadipate pathway for lysine biosynthesis or the 2-ox

20 ) catalyzes the fourth reaction of the alpha-aminoadipate pathway for lysine biosynthesis, the conver

21 ming)] catalyzes the final step in the alpha-aminoadipate pathway for lysine biosynthesis.

22 The alpha-aminoadipate pathway of lysine biosynthesis is modulated

23 The first enzyme in the alpha-aminoadipate pathway, homocitrate synthase (HCS), is the

24 cerevisiae together encode the 180-kDa alpha-aminoadipate reductase (AAR) in the biosynthetic pathway

25 The alpha-aminoadipate reductase (AAR) of this pathway catalyzes t

26 Lys5 covalently primes Lys2, allowing alpha-aminoadipate reductase activity by holo-Lys2 with cataly

27 ministration of an astroglial toxin, l-alpha-aminoadipate, reversed mechanical allodynia.

28 ted in phosphopantetheinylation of the alpha-aminoadipate semialdehyde dehydrogenase involved in lysi

29 ed it to ammonia, inorganic phosphate, and 2-aminoadipate semialdehyde.

30 d the most likely MSI target genes to be the aminoadipate-semialdehyde dehydrogenase AASDH and the so

31 The effects of glutamate and alpha-aminoadipate were also determined in purified Muller cel

32 alpha-Aminoadipate, which selectively target glial cells, also

33 trations of glutamate and its analogue alpha-aminoadipate, which specifically binds Muller glia, were

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