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1 from a nucleotide to a hydroxyl group of an aminoglycoside antibiotic.
2 stem-loop by neomycin, a naturally occurring aminoglycoside antibiotic.
3 on during the biosynthesis of gentamicin, an aminoglycoside antibiotic.
4 the active site, followed by binding of the aminoglycoside antibiotic.
5 high-level resistance to a broad spectrum of aminoglycoside antibiotics.
6 e important bacterial resistance enzymes for aminoglycoside antibiotics.
7 zyme, and it modifies more than 10 different aminoglycoside antibiotics.
8 lement) RNA was measured upon titration with aminoglycoside antibiotics.
9 ts induced on lipid membranes by amphiphilic aminoglycoside antibiotics.
10 oacoustic emissions, the salicylates and the aminoglycoside antibiotics.
11 hat are protected by tRNA, 50 S subunits, or aminoglycoside antibiotics.
12 inner ear can occur after damage induced by aminoglycoside antibiotics.
13 e structures are candidate receptors for the aminoglycoside antibiotics.
14 rRNA region comprises the natural target for aminoglycoside antibiotics.
15 isepamicin remains one of the more effective aminoglycoside antibiotics.
16 S rRNA constitutes the functional target for aminoglycoside antibiotics.
17 pect to their abilities to specifically bind aminoglycoside antibiotics.
18 endent O-phosphorylation of a broad range of aminoglycoside antibiotics.
19 hrotoxicity associated with the use of these aminoglycoside antibiotics.
20 ir predecessors during prolonged exposure to aminoglycoside antibiotics.
21 hlear hair cells in guinea pigs treated with aminoglycoside antibiotics.
22 tion, the oligonucleotide binds specifically aminoglycoside antibiotics.
23 ult, aging, and damage from intense sound or aminoglycoside antibiotics.
24 fusion system, with decreased resistance to aminoglycoside antibiotics.
25 ce, to develop a sensor for the detection of aminoglycoside antibiotics.
26 iosynthesis of 2-deoxystreptamine-containing aminoglycoside antibiotics.
27 miting factor in the clinical application of aminoglycoside antibiotics.
28 anism by which bacteria confer resistance to aminoglycoside antibiotics.
29 ment (SELEX) to isolate RNA aptamers against aminoglycoside antibiotics.
30 es the 2-deoxystreptamine ring common to all aminoglycoside antibiotics.
31 -deoxystreptamine ring (2-DOS) common to all aminoglycoside antibiotics.
32 pression causes hypersensitivity to multiple aminoglycoside antibiotics.
33 ly emerged with applications in the field of aminoglycoside antibiotics.
34 domonas aeruginosa, catalyzes acetylation of aminoglycoside antibiotics.
35 ) are common bacterial resistance enzymes to aminoglycoside antibiotics.
36 ens catalyzes adenylation and acetylation of aminoglycoside antibiotics.
37 ear are damaged by intense noise, aging, and aminoglycoside antibiotics.
38 ATN) produced by chemotherapeutic agents and aminoglycoside antibiotics.
39 action of aminoglycoside antibiotics with an aminoglycoside antibiotic 3'-phosphotransferase [APH(3')
40 phosphotransferases [APH(3')s] phosphorylate aminoglycoside antibiotics, a reaction that inactivates
41 sh lateral line hair cells after exposure to aminoglycoside antibiotics, a well characterized hair ce
42 boxamide, 1 (ORC-001), as protective against aminoglycoside antibiotic (AGA)-induced hair cell death.
43 gs can be extremely useful in developing new aminoglycoside antibiotics against resistant bacteria.
44 rial activity as neomycin, a clinically used aminoglycoside antibiotic, against Escherichia coli, Sta
47 ted that bactericidal antibiotics, including aminoglycoside antibiotics (AGAs), and toxic small molec
48 the determined conformations of enzyme-bound aminoglycoside antibiotics also suggested that interacti
50 values of the pKa of the amino groups of the aminoglycoside antibiotic amikacin and of its acetylated
53 ization of RNA aptamers that bind cofactors, aminoglycoside antibiotics, amino acids and peptides wit
55 inhibition patterns indicate that binding of aminoglycoside antibiotic and ATP occurs in a random man
56 l model for specific ribosome recognition by aminoglycoside antibiotics and a possible mechanism for
57 ma membrane, and increased susceptibility to aminoglycoside antibiotics and cationic antimicrobials.
59 saccharide Pel, which protects bacteria from aminoglycoside antibiotics and contributes to biofilm ar
60 The suf13-1 suppressor alters sensitivity to aminoglycoside antibiotics and reduces the accumulation
61 ansferase IIIa [APH(3')-IIIa] phosphorylates aminoglycoside antibiotics and renders them ineffective
64 te RNA oligonucleotide specifically binds to aminoglycoside antibiotics and the structure of the RNA-
66 Recent emergence of microbial resistance to aminoglycoside antibiotics, and the documented cytotoxic
67 ranslational readthrough of stop codons, the aminoglycoside antibiotics are currently being tested fo
72 t, in the absence of metal ions, a number of aminoglycoside antibiotics at 10 mM concentration promot
76 sses of ototoxic drugs are cisplatin and the aminoglycoside antibiotics, both of which are toxic to m
77 the geometrical and electrostatic nature of aminoglycoside antibiotics bound to a modifying enzyme a
78 ymes that cause high levels of resistance to aminoglycoside antibiotics by the organisms that harbor
81 addition, commonly used antibiotics, such as aminoglycoside antibiotics, can lead to disruption of ot
82 f Pseudomonas aeruginosa that is a potential aminoglycoside antibiotic combination therapy target.
84 igate the interaction between tobramycin, an aminoglycoside antibiotic commonly administered to CF pa
86 almost half of a century, we have known that aminoglycoside antibiotics corrupt ribosomes, causing tr
87 and mechanism of TA toxin action drawn from aminoglycoside antibiotics: Doc toxicity is the result o
89 555A>G predisposes to hearing loss following aminoglycoside antibiotic exposure in an idiosyncratic d
94 from 1-day-old chicks and incubated with the aminoglycoside antibiotics gentamicin or neomycin (both
100 n mimicked the effects of treatment with the aminoglycoside antibiotic hygromycin B (HygB): Both Doc
101 ues, such as hyperosmolarity and presence of aminoglycoside antibiotics, (ii) narrowed their metaboli
102 The first enzyme-bound conformation of an aminoglycoside antibiotic in the active site of an amino
103 ransferases mediate high level resistance to aminoglycoside antibiotics in Gram-positive microorganis
104 The specificity of neomycin B and related aminoglycoside antibiotics in their interaction with the
105 on-derived kinase that confers resistance to aminoglycoside antibiotics, in Escherichia coli under se
108 we show that subinhibitory concentrations of aminoglycoside antibiotics induce biofilm formation in P
110 l subunit RNA of the bacterial ribosome, the aminoglycoside antibiotics inhibit protein synthesis, ca
115 hypothesis that the ototoxicity produced by aminoglycoside antibiotics involves the excitotoxic acti
116 initial loss of function due to exposure to aminoglycoside antibiotics is independent of the vascula
117 most serious side-effect of the widely used aminoglycoside antibiotics is irreversible intracellular
119 ays a significant role in resistance against aminoglycoside antibiotics, is controlled by a translati
120 ete proton and carbon NMR assignments of the aminoglycoside antibiotic isepamicin at pH 6.8 as well a
122 show that the binding of this RNA target to aminoglycoside antibiotics, its cognate ligands, can be
126 sreading, we asked if streptomycin (Str), an aminoglycoside antibiotic known to promote mistranslatio
131 f nuclear translocation of angiogenin by the aminoglycoside antibiotic neomycin inhibited PC-3 cell t
132 his report, we show that a derivative of the aminoglycoside antibiotic neomycin, in which all of the
133 r the acridine derivative CGP 40336A and the aminoglycoside antibiotic neomycin, which bind to differ
134 interactions that govern the binding of the aminoglycoside antibiotics neomycin and kanamycin B to A
135 aration of a series of four analogues of the aminoglycoside antibiotics neomycin and paromomycin is d
136 echniques to characterize the binding of the aminoglycoside antibiotics neomycin, paromomycin, and ri
138 ANG's nuclear translocation by neomycin, an aminoglycoside antibiotic (not G418-neomicin), resulted
140 a recent trend in evolution of resistance to aminoglycoside antibiotics, of which four examples have
142 ting cells that express the mRNA with either aminoglycoside antibiotics or several nonantibiotic comp
143 to characterize the interaction between the aminoglycoside antibiotic paromomycin and a small model
145 The mof4-1 strain is more sensitive to the aminoglycoside antibiotic paromomycin than a upf1 delta
149 f aminosugars, from which a novel library of aminoglycoside antibiotics (pyranmycins) was synthesized
150 ng the efficacy of PTC124 with the classical aminoglycoside antibiotic read-through agent geneticin (
151 of high RNA target selectivity displayed by aminoglycoside antibiotics results from both their elect
154 ronically blocking calcium channels with the aminoglycoside antibiotic streptomycin from onset of dis
155 hacrynic acid (EA) is known to interact with aminoglycoside antibiotics such as gentamicin (GM).
156 ow that calcineurin mutants are sensitive to aminoglycoside antibiotics such as hygromycin B while pm
162 Neomycin is a large, positively charged, aminoglycoside antibiotic that has previously been shown
163 in RGS4, similar to those contained in some aminoglycoside antibiotics that are known to bind coatom
165 an improved understanding of how amphiphilic aminoglycoside antibiotics that bind to negatively charg
167 ptamine) is the most conserved element among aminoglycoside antibiotics that bind to the A-site.
169 tion confers resistance to a subclass of the aminoglycoside antibiotics that contain a 6' amino group
170 S rRNA A-site model oligonucleotide and four aminoglycoside antibiotics that exhibit a broad range of
172 characterize the binding of three classes of aminoglycoside antibiotics to ribosomal RNA subdomains.
173 useful to rapidly evaluate the potential of aminoglycoside antibiotics, to inhibit the Rev-RRE inter
174 RNA aptamer (J6RNA) selected to bind to the aminoglycoside antibiotic tobramycin is shown to do so w
176 been selected which were able to bind to the aminoglycoside antibiotic tobramycin with high affinity.
177 echniques to characterize the binding of the aminoglycoside antibiotic, tobramycin, to the polymeric
178 r undergo apoptosis after acoustic trauma or aminoglycoside antibiotic treatment, causing permanent a
179 ility to fluoroquinolone, cephalosporin, and aminoglycoside antibiotics using disk diffusion assays.
181 he antibacterial activity of kanamycin class aminoglycoside antibiotics, we have accomplished the syn
182 he enzyme that modifies the essential N3B of aminoglycoside antibiotics, were determined by NMR spect
183 ues of the amino functions in a target-bound aminoglycoside antibiotic, which permitted dissection of
184 The decoding process is perturbed by the aminoglycoside antibiotics, which also interact with thi
188 doribostamycin resulting in the synthesis of aminoglycoside antibiotics with activity against drug-re
189 py has been used to study the interaction of aminoglycoside antibiotics with an aminoglycoside antibi
190 romising avenue for the development of novel aminoglycoside antibiotics with improved efficacy and re
191 B-DNA structures by conjugating neomycin, an aminoglycoside antibiotic, with the B-DNA minor groove b
192 B-DNA structures by conjugating neomycin, an aminoglycoside antibiotic, with the B-DNA minor groove b
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