ライフサイエンスコーパス: aminohippurate

1 t not of estradiol 17beta-d-glucuronide or p-aminohippurate.

2 RPF was measured by clearance of para-aminohippurate.

3 ohippurate (18F-PFH) is similar to that of p-aminohippurate, a gold standard for the measurement of e

4 hylammonium), decynium-22, carnitine, PHA (p-aminohippurate), alanine, or inosine.

5 OAT1 inhibitor) and partially reversed by p-aminohippurate (an OAT1 substrate).

6 nd 69 age-matched healthy subjects with para-aminohippurate and inulin clearances and their response

7 h pharmacokinetic properties comparable to p-aminohippurate and superior to those of both (99m)Tc-mer

8 In addition, p-aminohippurate and the dicarboxylates adipate and glutar

9 Sodium, potassium, lithium, para-aminohippurate, and creatinine clearances were measured

10 retion of the prototypic organic anion, para-aminohippurate, as well as of a large number of commonly

11 sport of the shared OAT1/OAT3 substrate, rho-aminohippurate, behaved similarly, except that stimulati

12 d loss of organic anion transport (e.g. para-aminohippurate) both ex vivo (in isolated renal slices)

13 (inulin), effective renal plasma flow (para-aminohippurate), BP, and hemodynamic responses to an inf

14 Renal plasma flow was measured by para-aminohippurate clearance and was converted to blood flow

15 red pre- and post-CPAP using inulin and para-aminohippurate clearance techniques at baseline and in r

16 Renal plasma flow (para-aminohippurate clearance) and glomerular filtration rate

17 d part of the study, renal plasma flow (para-aminohippurate clearance) and glomerular filtration rate

18 nd renal vascular responses (inulin and para-aminohippurate clearance) to graded doses of an angioten

19 , and renal plasma flow was measured by para-aminohippurate clearance.

20 Para-aminohippurate extraction was likewise reduced to simila

21 teral GFR, renal plasma flow (RPF), and para-aminohippurate extraction was measured 1 h before and 1

22 for taurocholate, estrone sulfate, and para-aminohippurate in renal slices from wild-type mice, wher

23 restoration of the inhibitory effect of para-aminohippurate (% inhibition 34 +/- 4%).

24 orted probenecid-sensitive uptake of [(3)H]p-aminohippurate (K(m) = 4 microM), which was trans-stimul

25 necid-sensitive and pH-dependent uptake of p-aminohippurate (Km = 15.4 FtM, V,,, ..ax = 20.6 pmol/106

26 , digoxin, and prostaglandin E(2), but not p-aminohippurate or S-dinitrophenyl glutathione.

27 xtracellular alphaKG on the kinetics of para-aminohippurate (PAH) and cidofovir transport was examine

28 Effects of these residues on p-aminohippurate (PAH) and cidofovir transport were assess

29 es the transport of organic anions such as p-aminohippurate (PAH) and estrone sulfate as well as the

30 Para-aminohippurate (PAH) and estrone-3-sulfate transport acr

31 First, 5 mM p-aminohippurate (PAH) cis-inhibited the uptake of 1 micro

32 teral GFR, renal plasma flow (RPF), and para-aminohippurate (PAH) extraction were measured 1 h before

33 he prototypical organic anion substrate para-aminohippurate (PAH) reduced ochratoxin A secretion by a

34 The maximal rate of p-aminohippurate (PAH) secretion, in micromol/min per 100

35 The transporter-mediated p-aminohippurate (PAH) uptake was saturable, probenecid-se

36 rototypical substrates for Oat1, including p-aminohippurate (PAH), and was trans-stimulated when oocy

37 The uptakes of p-aminohippurate (PAH), estrone sulfate, and ochratoxin A

38 tes was inhibited by sulfate, oxalate, and p-aminohippurate (PAH), indicating affinity for these anio

39 ds and by renal clearance of inulin and para-aminohippurate (PAH), simultaneous cardiorenal hemodynam

40 ened for probenecid-sensitive transport of p-aminohippurate (PAH).

41 well as the prototypical OAT substrate para-aminohippurate (PAH).

42 flow were measured with iothalamate and para-aminohippurate, respectively.

43 Para-aminohippurate significantly inhibited uric acid uptake

44 (tissue/medium (T/M) approximately 8) and p-aminohippurate (T/M = 2) transport.

45 OAT1, and the uptake of model substrate para-aminohippurate was studied in COS-7 cells expressing the

46 The renal clearances of inulin and para-aminohippurate were used to measure GFR and renal plasma