ライフサイエンスコーパス: aminomethyl

1 A series of bioisosteric 4-(aminomethyl)-1-hydroxypyrazole (4-AHP) analogues of musc

2 enylallyllithium 7, and 2-bis(2-methoxyethyl)aminomethyl-1,3-diphenylallyllithi um 8, are indeed full

3 itative N,N-dichlorination of (R)- and (S)-2-aminomethyl-1,4-benzodioxane and successive functional g

4 olscine (7.75), 2-(2,6-dimethoxyphenoxyethyl)aminomethyl-1,4-benzodioxane hydrochloride (WB-4101; 6.8

5 synthesis of the gamma-amino acid (1R,2R)-2-aminomethyl-1-cyclopentane carboxylic acid (AMCP) and an

6 NMR studies shows that 2-bis(2-methoxyethyl)aminomethyl-1-phenylallyllithium 7, and 2-bis(2-methoxye

7 After selective attachment of 2-aminomethyl-18-crown-6 (18c6), individual AP lesions are

8 -(Aminomethyl)-2,6-difluorophenol (6) and 4-(aminomethyl)-2, 6-difluorophenol (7) were synthesized in

9 nt anthracene dimer 3 paired with 1,3,5-tris(aminomethyl)-2,4,6-triethylbenzene 2.

10 3-(Aminomethyl)-2,6-difluorophenol (6) and 4-(aminomethyl)-

11 system ThiXYZ transports N-formyl-4-amino-5-(aminomethyl)-2-methylpyrimidine (FAMP), a thiamin salvag

12 detected by the fluorogenic traps 3-amino,4-aminomethyl-2',7'-difluorofluorescein diacetate and diam

13 In all genotypes, much 3-amino,4-aminomethyl-2',7'-difluorofluorescein diacetate fluoresc

14 Herein, we report the synthesis of 4'-C-aminomethyl-2'-deoxy-2'-fluorouridine, a therapeutically

15 dynamics simulations revealed that the 4'-C-aminomethyl-2'-O-methyl modified nucleotides adopt South

16 is work has implications for the use of 4'-C-aminomethyl-2'-O-methyl modified nucleotides to overcome

17 The linear syntheses of 4'-C-aminomethyl-2'-O-methyl uridine and cytidine nucleoside

18 modified, 2'-fluoro-, 2'-O-methyl-, and 4'-C-aminomethyl-2'-O-methyluridine showed the chemical natur

19 4,5-diaminofluorescein (DAF-2) and 3-amino,4-aminomethyl-2'7'-difluorescein (DAF-FM).

20 f CO(2) and lignocellulose-derived monomer 5-aminomethyl-2-furoic acid (AMF).

21 Herein, we report the development of poly(5-aminomethyl-2-furoic acid) (PAMF), a semicrystalline SAP

22 ctivity as a 5-HT(2C) agonist, a series of 1-aminomethyl-2-phenylcyclopropanes was investigated as 5-

23 Inhibitor 19b with a (R)-aminomethyl-2-pyrrolidinone and a Cp-THF was shown to be

24 se (PR) inhibitor containing a novel P1' (R)-aminomethyl-2-pyrrolidinone group.

25 that chemical vapor polymerization (CVP) of aminomethyl[2.2]paracyclophane into nematic liquid cryst

26 .g., hydroxymethyl[2.2]paracyclophane versus aminomethyl[2.2]paracyclophane versus [2.2]paracyclophan

27 phenyl)pyridin-1-ium (4-I-AMPP(+)) and 1-(4-(aminomethyl)-3-iodophenyl)pyridin-1-ium (3-I-AMPP(+)) de

28 edications for cocaine abuse, a series of 2-(aminomethyl)-3-phenylbicyclo[2.2.2]- and -[2.2.1]alkane

29 e gamma-CBAA is the (1R,2S,3R)-configured 2-(aminomethyl)-3-phenylcyclobutanecarboxyl moiety (1a) or

30 29)]; isochromans [(1R,3S)-3-(1'adamantyl)-1-aminomethyl-3,4-dihydo-5,6-dihydroxy-1H-2-benzo pyran (A

31 -benzo pyran (A77636) and (1R,3S)-3-phenyl-1-aminomethyl-3,4-dihydo-5,6-dihydroxy-1H-2-benzopyran (A6

32 c acid (7) and tert-butyl (+/-)-(2S,3R,4R)-2-aminomethyl-3-bis(tert-butyloxycarbonyl)amino-1-(N'-eth

33 uoronium ions react with alkenes 5 to give 4-aminomethyl-3-hydroxycyclobutene 11, derived by ring cle

34 n-propylamino)tetralin (8-OH-DPAT), 25 ng (5-aminomethyl-3-hydroxyisoxazole)hydrobromide (muscimol),

35 methyl-, 2-aminomethyl-, and N-substituted 2-aminomethyl-3-hydroxymorphinans.

36 By using 5-aminomethyl-3-hydroxysoxazole to temporarily inactivate

37 ree psoralens, 8-methoxypsoralen (8-MOP), 4'-aminomethyl 4,5', 8-trimethylpsoralen (AMT), and the nov

38 beta-(Aminomethyl)-4-chlorobenzenepropanoic acid (baclofen) wa

39 Potencies of the full agonists R-(+)-beta-(aminomethyl)-4-chlorobenzenepropanoic acid hydrochloride

40 e-guided design, we developed substituted 2-(aminomethyl)-4-ethynyl-6-iodophenols as p53-Y220C stabil

41 s spectra of fatty acids conjugated to 1-(3-(aminomethyl)-4-iodophenyl)pyridin-1-ium (4-I-AMPP(+)) an

42 For one psoralen derivative, 4'-aminomethyl-4,5',8-trimethylpsoralen (AMT), the photorea

43 quent lead molecule from this series, (+)-6-(aminomethyl)-5-(2,4-dichlorophenyl)-N-(1-ethyl-1H-pyrazo

44 Two series with 2-(aminomethyl)-5-chlorobenzylamide and 4-amidinobenzylamid

45 Pregabalin [S-[+]-3-isobutylGABA or (S)-3-(aminomethyl)-5-methylhexanoic acid, Lyrica] is an antico

46 lin (PGB) [(S)-(+)-3-isobutyl-GABA or (S)-3-(aminomethyl)-5-methylhexanoic acid] can produce concentr

47 synthetic routes to enantiomerically pure 3'-aminomethyl-5'-carboxy-3',5'-dideoxy nucleosides, monome

48 -9-hydroxyfluoren-9(R)-ylcarbonyl-l-prolyl-2-aminomethyl-5-chlorobenz ylamide (19b), with high potenc

49 re, 9-hydroxy-9-fluorenylcarbonyl-l-prolyl-2-aminomethyl-5-chlorobenzylamide (2), with improved poten

50 ), PKC (administration of Ro 31-82425; 2-[8-(aminomethyl)-6,7,8,9-tetrahydropyrido[1,2-a]indol-3-yl]-

51 g in identification of racemic-trans-(3-((4-(aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)

52 nolic group for the aminosulfonyl moiety [1-(aminomethyl)-6-hydroxynaphthalene (23) and 8-hydroxy-1,2

53 ylmethyl-7,8-dihydronormorphinone and 7alpha-aminomethyl-6,14-endoethanonororipavine have pronounced

54 uX(CNN)(dppb)] (1, X = Cl; 2, X = H; CNN = 2-aminomethyl-6-tolylpyridine, dppb = 1,4-bis(diphenylphos

55 racterization of DNA oligomers containing 7-(aminomethyl)-7-deazaguanine (1) residues using a variety

56 A set of nine 4-aminomethyl-7-alkoxycoumarin derivatives was synthesized

57 leasing hormone (GnRH) antagonists such as 6-aminomethyl-7-aryl-pyrrolo[1,2-a]pyrimid-4-ones (5) and

58 SAR from bicyclic GnRH antagonists such as 6-aminomethyl-7-arylpyrrolo[1,2-a]pyrimid-4-ones (1) and 2

59 no-7-deazaguanine (dPreQ(0)) and 2'-deoxy-7- aminomethyl-7-deazaguanine (dPreQ(1)).

60 oup of 7-cyano-7-deazaguanine (preQ(0)) to 7-aminomethyl-7-deazaguanine (preQ(1)), the only nitrile r

61 nverts 7-cyano-7-deazaguanine (preQ0) into 7-aminomethyl-7-deazaguanine (preQ1) for the biosynthesis

62 ction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1), a late step in the q

63 of the SD sequence of an mRNA hosting the 7-aminomethyl-7-deazaguanine (preQ1)-sensing riboswitch.

64 The preQ1 (7-aminomethyl-7-deazaguanine) riboswitch family comprises

65 trol bacterial genes in response to preQ1 (7-aminomethyl-7-deazaguanine), a precursor to the essentia

66 ndent reduction of 7-cyano-7-deazaguanineto7-aminomethyl-7-deazaguanine, a late step in the biosynthe

67 ynthesized and modified with the precursor 7-aminomethyl-7-deazaguanine, and this served as an effici

68 nts of ligand binding in the prequeuosine (7-aminomethyl-7-deazaguanine, preQ(1)) bacterial riboswitc

69 o aromatic rings and basic nitrogen atom, 9-(aminomethyl)-9,10-dihydroanthracene (AMDA; 1) is remarka

70 The effects of 3-position substitution of 9-aminomethyl-9,10-dihydroanthracene (AMDA) on 5-HT 2A rec

71 nce and presence of 9-[(N-3-phosphonopropyl)-aminomethyl-9-deazahypoxanthine, providing a basis for n

72 NMe2)(mu-O)3 (5) containing novel chelating (aminomethyl)amide-N(Me)CH2NMe2 ligands.

73 le of the amine, (b) a 1:1 complex with tris(aminomethyl)amine in which each calixarene unit contains

74 0 regioselectively, which was converted to 2-aminomethyl analogue 1 via sulfinamide 2.

75 Derivatives with various aminomethyl and aminoethyl substituents on the para posi

76 phore to control the relative disposition of aminomethyl and carboxyl substituents.

77 rong evidence to support the notion that the aminomethyl and hydroxyl groups in the capping group of

78 oxymorphinans, including 2-hydroxymethyl-, 2-aminomethyl-, and N-substituted 2-aminomethyl-3-hydroxym

79 The asymmetric hydroamination of (aminomethyl)anilines gave rise to 3-vinyl-1,4-BZDs with

80 l analogs and found that the substitution of aminomethyl at the meta-position greatly enhances inacti

81 difications examined included, at 3': amino, aminomethyl, azido, guanidino, ureido; and at 5': uronam

82 These 4-(aminomethyl)benzamide-based inhibitors are also effectiv

83 ophenyl)-4-[N-(pyridine-3-ylmethoxy-carbonyl)aminomethyl]benzamide (MS-275)] infusion also reverses t

84 nophenyl)-4-[N-(pyridin-3-yl-methoxycarbonyl)aminomethyl]benzamide derivative (MS-275), which is a po

85 ophenyl)-4-[N-(pyridine-3-ylmethoxy-carbonyl)aminomethyl]benzamide].

86 phenyl)-4-[N-(pyridine-3-yl-methoxycarbonyl)-aminomethyl]-benzamide (MS-275), and vorinostat led to d

87 These 4-(aminomethyl)benzamides are suitable for further optimiza

88 esis, and evaluation of a series of related (aminomethyl)benzamides in assays predictive of antipsych

89 chelator, N,N,N',N'-tetrapropionato-1,3-bis(aminomethyl)benzene (TPDBA), for complete extraction of

90 chelator, N,N,N',N'-tetrapropionate-1,3-bis(aminomethyl)benzene (TPDBA), has been used that permits

91 esent a solid molecular triamine, 1,3,5-tris(aminomethyl)benzene (TriH), that rapidly captures large

92 pling fluorinated carboxylic acids onto poly(aminomethyl)benzene scaffolds.

93 itatively this reversal is compatible with 4-aminomethyl benzoic acid competitively binding to the ex

94 mmetrically from a central scaffold (bis-3,5-aminomethyl benzoic acid, AMAB) to connect two ethacryni

95 -amino) propyl-beta-cyclodextrin, per-6-S-(3-aminomethyl) benzyl-alpha-cyclodextrin, per-6-S-(3-amino

96 ethyl) benzyl-alpha-cyclodextrin, per-6-S-(3-aminomethyl) benzyl-beta-cyclodextrin, per-6-S-(3-aminom

97 methyl) benzyl-beta-cyclodextrin, per-6-S-(3-aminomethyl) benzyl-gamma-cyclodextrin, methyltriphenylp

98 Recently, we described N-(3-(aminomethyl)benzyl)acetamidine (13) as a slow, tight-bin

99 N-(3-(Aminomethyl)benzyl)acetamidine (1400W) was a slow, tight

100 N-(3-(Aminomethyl)benzyl)acetamidine (1400W) was reported to b

101 We have investigated the effect of N-(3-(aminomethyl)benzyl)acetamidine (1400W), a novel and high

102 ucible nitric oxide synthase inhibitor N-(3-(aminomethyl)benzyl)acetamidine dihydrochloride (1400W) a

103 s, N(5)-(1-iminoethyl)-L-ornithine and N-(3-(aminomethyl)benzyl)acetamidine, provide clues on how thi

104 e were treated with the iNOS inhibitor N -(3-aminomethyl)benzyl-acetamindine (1400W).

105 tor chlormethiazole and iNOS inhibitor N-(3-(aminomethyl)-benzyl) acetamidine abrogated the toxicity

106 effects of selective NOS II antagonists N-(3-aminomethyl) benzylacetamidine dihydrochloride (1400W) a

107 ation was suppressed by aminoguanidine, N-(3-aminomethyl)benzylacetamidine (1400W), or allopurinol, s

108 hyl)ornithine (L-NIO) or iNOS inhibitor N-(3-aminomethyl)benzylacetamidine, 2HCl (1400W) had no effec

109 paring polycyclic N,O-acetals from simple 1-(aminomethyl)-beta-naphthols and 2-(aminomethyl)-phenols.

110 synthesis with iodo-bicyclopentanes to make aminomethyl bicyclobutanes.

111 ds, result in radical formation and initiate aminomethyl (CH(2)NH(2)) and amino ([Formula: see text](

112 The 7-hydroxy-2-(aminomethyl)chroman moiety was observed to be the primar

113 luation of a D(2/3)R agonist ligand from the aminomethyl chromane (AMC) class-(R)-2-[(4-(18)F-fluorob

114 nzoxepanes), including a synthesis of the 2-(aminomethyl)chromane part of sarizotan, and a total synt

115 A series of 2-(aminomethyl)chromans (2-AMCs) was synthesized and evalua

116 ia a carbene complex (1d) that isomerizes to aminomethyl complex 7d.

117 h an intramolecular S(N)2-type attack of the aminomethyl-containing aryl ring on the cyclopropane rin

118 ifferences in their rates of hydrolysis of 5-aminomethyl coumarin (AMC) from C-terminally labeled pep

119 s-Menten kinetic analyses of 21 oligopeptide aminomethyl-coumarin substrates.

120 Strained aminomethyl-cycloalkanes are a recurrent scaffold in med

121 igomers (di-, tri-, and tetramers) of cis-2-(aminomethyl)cyclobutane carboxylic acid, a gamma-amino a

122 trast, the ionophore with the cis-1,3,5-tris(aminomethyl)cyclohexane scaffold exhibits a more Hofmeis

123 Tris(2-aminoethylamine) and cis-1,3,5-tris(aminomethyl)cyclohexane were employed as the scaffolds.

124 psilon-aminocaproic acid (EACA) and trans-4-(aminomethyl)cyclohexane-1-carboxylic acid (AMCHA), which

125 that the alpha2delta ligands gabapentin [1-(aminomethyl)cyclohexaneacetic acid] and pregabalin (PGB)

126 usly, it was determined that OA and trans-4-(aminomethyl)cyclohexanecarboxylic acid (AMCHA) (K(a) app

127 , zwitterions of similar size such as trans-(aminomethyl)cyclohexanecarboxylic acid (AMCHA) and p-ben

128 , 7-aminoheptanoic acid (7-AHpA), and trans-(aminomethyl)cyclohexanecarboxylic acid (AMCHA) to each o

129 of r(K57D)K3 for the lysine analogue trans-(aminomethyl)cyclohexanecarboxylic acid (AMCHA) was inves

130 These were trans-4-(aminomethyl)cyclohexanecarboxylic acid (t-AMCHA), prolin

131 agonist L-054,264 (N-[(1R)-2-[[[(1S*,3R*)-3-(aminomethyl)cyclohexyl]methyl]amino]-1-(1H-indol-3-ylm e

132 tive organocatalytic route to the (1S,2R)-2-(aminomethyl)cyclopentane-1-carboxylic acid monomer precu

133 ponent coupling reaction to form substituted aminomethyl-cyclopentanes from secondary amines, cyclopr

134 zed enantioselective C(sp(3))-H arylation of aminomethyl-cyclopropanes and -cyclobutanes with aryl bo

135 The 4-tert-butyl and 4-aminomethyl derivatives of phenylalanine (tBuPhe and AMP

136 omomethyl porphyrins were converted to their aminomethyl derivatives, H2(alpha,alpha-AP) and H2(alpha

137 was subjected to reductive amination to give aminomethyl derivatives.

138 se bis-silyl ketene acetals with a silylated aminomethyl ether, followed by hydrolytic workup, to giv

139 ormation and instead suggest that protonated aminomethyl functions as an electron-withdrawing group t

140 gamma-Aminomethyl-gamma-lactones are versatile chiral building

141 chiral-at-ruthenium catalysts, chiral gamma-aminomethyl-gamma-lactones containing a quaternary carbo

142 The presence of the o-aminomethyl group enhances the affinity towards diols at

143 Further, the aminomethyl group is believed to be involved in the turn

144 The introduction of an aminomethyl group on the phenyl group led to monomer X,

145 Addition of the aminomethyl group to Phe substantially improved the sele

146 elded tetra-substituted sulfamidates with an aminomethyl group.

147 ta as of 2019 whilst also highlighting why o-aminomethyl groups are so widely used, and the role they

148 ic intermediates bearing carbamoylmethyl and aminomethyl groups at C-8.

149 ed and connected with secondary and tertiary aminomethyl groups, amide bonds, and hydroxymethylene gr

150 ety in DXP was replaced by hydroxymethyl and aminomethyl groups.

151 yrrolo[1,2-a]pyrimid-4-ones (5) and 2-aryl-3-aminomethyl-imidazolo[1,2-a]pyrimid-5-ones (6a,b), a ser

152 ndensed with indoles affording an array of 3-aminomethyl indoles.

153 A novel palladium-catalyzed approach to 2-(aminomethyl)indoles from 3-(o-trifluoroacetamidoaryl)-1-

154 Potent and much more selective N-aminomethyl-isatin-beta-thiosemicarbazones were discover

155 the inducible nitric oxide synthase (iNOS) N-aminomethyl-L-lysine.

156 We report herein an alternative aminomethyl linker that delivers similar potency and imp

157 nzymes, HydG, HydE, and HydF, as well as the aminomethyl-lipoyl-H-protein (H(met)) of the glycine cle

158 and, a process recently shown to involve the aminomethyl-lipoyl-H-protein from the glycine cleavage s

159 for the first time an essential role for the aminomethyl-lipoyl-H-protein of the GCS in hydrogenase m

160 To introduce the aminomethyl moiety of 2 via a palladium-catalyzed cyanat

161 inhibitors identified acyl derivatives of 4-(aminomethyl)-N-hydroxybenzamide as potent leads with une

162 xyphenyl)-2-chloro-5-[2-(bis(2-pyridylmethyl)aminomethyl)-N-meth ylaniline]-6-hydroxy-3-xanthanone) i

163 exes, where BPAMP is [2-(bis(2-pyridylmethyl)aminomethyl)-N-methylaniline]-phenol and M = Mn(2+), Zn(

164 plasma amine oxidase (BPAO), namely, (2-(6-(aminomethyl)naphthalen-2-yloxy)ethyl)trimethylammonium (

165 ts such as fluoro, bromo, nitro, acetyl, and aminomethyl on the isoquinoline ring resulted in a signi

166 e report the design of chiral mono-protected aminomethyl oxazoline ligands that enable desymmetrizati

167 the first time using chiral acetyl-protected aminomethyl oxazoline ligands.

168 trated to deliver direct access to 3-allyl-3-aminomethyl oxindoles and 5-silyl methyl spiro[pyrrolidi

169 catalyst-free conditions afforded 3-allyl-3-aminomethyl oxindoles with good stereoselectivity (ee up

170 n two complementary polymer coatings, poly(4-aminomethyl-p-xylylene-co-p-xylylene) and poly(4-formyl-

171 RT variants containing meta-Tyr, nor-Tyr, aminomethyl-Phe, and 1- and 2-naphthyl-Tyr were produced

172 l permeability, yielding azido-Phe-Leu-Leu-4-aminomethyl-Phe-methyl vinyl sulfone (4a, LU-102), and a

173 Aminomethyl-Phe115 RT incorporated dCTP more efficiently

174 ontaining these side chains suggest that the aminomethyl-Phe115 substitution provides new hydrogen bo

175 all inhibited by ethacrynic acid and certain aminomethyl phenols.

176 simple 1-(aminomethyl)-beta-naphthols and 2-(aminomethyl)-phenols.

177 yl-polyoxazole moiety is linked by a 1,3-bis(aminomethyl)phenyl group with a 5-(2-aminoethyl)- (18) o

178 S inhibition potency was achieved with N-(3-(aminomethyl)phenyl)-2-furanylamidine (77) (Ki-nNOS = 0.0

179 idine nitrogen and phenyl ring to give N-(3-(aminomethyl)phenyl)acetamidine (14) dramatically altered

180 Finally, alpha-fluoro-N-(3-(aminomethyl)phenyl)acetamidine (74) (Ki-nNOS = 0.011 mic

181 ity to N-terminal phenylalanine (Phe) and 4-(aminomethyl)phenylalanine (AMPhe) and prevents their rem

182 the preclinical development of DPC602, a 2-(aminomethyl)phenylpyrazole analogue, as a highly potent,

183 terized a new tagging reagent, (3R,4S)-1-(4-(aminomethyl)phenylsulfonyl)pyrrolidine-3,4-diol (APPD),

184 This includes aminomethyl phosphonate [AMP](2-), 1-aminoethyl phosphon

185 itively inhibited by alternative substrates (aminomethyl phosphonate [AMPA] and N-methyl glyphosate [

186 ng the concentration of glyphosate and AMPA (aminomethyl phosphonic acid, one of its major degradatio

187 A 4-(aminomethyl)phthalazin-1(2H)-one hit was identified thro

188 3'-dicarboxylate) with the cyclic diamine 2-(aminomethyl)piperidine (2-ampd) produces an adsorbent th

189 tion by synthesis of an N-methyl-3-fluoro-4-(aminomethyl)piperidine urea led to compound 30 that has

190 t and cyclic diammonium cations of 3- and 4-(aminomethyl)piperidinium (3AMP and 4AMP respectively): (

191 general formula (A')(A)Pb(2)Br(7) ((A' = 3-(aminomethyl)piperidinium (3AMP) and 4-(aminomethyl)piper

192 report on 2D DJ phase perovskites using a 3-(aminomethyl)piperidinium (3AMP) organic spacer for the f

193 = 3-(aminomethyl)piperidinium (3AMP) and 4-(aminomethyl)piperidinium) (4AMP); A = methylammonium (MA

194 he aliphatic cation of the same size (AMP = (aminomethyl)piperidinium), the aromatic spacers increase

195 AMP = 3-(aminomethyl)piperidinium; 4AMP = 4-(aminomethyl)piperidinium), using a combination of ultraf

196 ly, (3AMP)PbI(4) and (4AMP)PbI(4) (3AMP = 3-(aminomethyl)piperidinium; 4AMP = 4-(aminomethyl)piperidi

197 -OIHP (AMP)(MA)Pb(2)I(7) (DJP(n=2), AMP = 4-(aminomethyl)piperidinium; MA = methylammonium), which sh

198 Aminomethyl polystyrene resin was reacted with 4-(5'-for

199 Two classes of aminomethyl polystyrene resin-bound linkers of p-acetoxy

200 ating reagent was subjected to reaction with aminomethyl polystyrene resin-bound p-acetoxybenzyl alco

201 litated using a solid phase, N-(2-aminoethyl)aminomethyl polystyrene.

202 (EDA), piperazine (PPZ), and methyl 2,2-bis(aminomethyl)propionate (COOMe) cores.

203 the positively charged 4-amino-TEMPO and 3-(aminomethyl)-proxyl radical and polar 4-hydroxy-TEMPO ra

204 ariety of substitution patterns as well as 3-aminomethyl-pyrazolo[3,4-b]pyridines.

205 ased on a simple post-growth treatment of 3-(aminomethyl)pyridine (3-APy) on top of a perovskite thin

206 se novel RTILs were readily prepared from 2-(aminomethyl)pyridine and amino acid ester derived isocya

207 More than 25 new cobalt-(aminomethyl)pyridine complexes were developed as catalys

208 for alkenyl acid derivatives containing a 2-(aminomethyl)pyridine derivative as a directing group.

209 4-AP, 4-(aminomethyl)pyridine, 4-(methylamino)pyridine, and 4-di(

210 -morpholinylmethyl)-5-aminopyridine-, and 5-(aminomethyl)pyridine-2-carboxaldehyde thiosemicarbazones

211 ral formula of A'A(n-1)Pb(n)I(3n+1) (A' = 4-(aminomethyl)pyridinium (4AMPY), A = methylammonium (MA),

212 (3)(+) group from 4AMPY to 3AMPY (3AMPY = 3-(aminomethyl)pyridinium), the stacking of the inorganic l

213 Of these diamines, (R)-2-(aminomethyl)pyrrolidine is a particularly potent and sel

214 discovery and optimization of a series of 4-(aminomethyl)quinolin-2(1H)-ones, exemplified by 34, that

215 ubstituted alkenyl sulfones through an alpha-aminomethyl radical addition-elimination pathway.

216 withC bond attacks by its Calpha atom on the aminomethyl radical functionality N(Me)-CH2.

217 withC bond attacks by its Calpha atom on the aminomethyl radical functionality N(Me)-CH2. presumably

218 This was attached to aminomethyl resin and elongated using standard Fmoc prot

219 This study highlights the potential of aminomethyl salicylaldehydes to generate conformationall

220 Standard manipulations produced the aminomethyl side chain.

221 its, each bearing an ethyl side chain and an aminomethyl side chain.

222 he benzylic position was used to install the aminomethyl side-chain in the C(1)-aromatic substituent.

223 nct structural subclass of N-ethylene linked aminomethyl SPCs (eAmSPCs) that are up to 64-fold more p

224 implifies the construction of functionalized aminomethyl-strained cycloalkanes, which we believe will

225 When installed at the beta-position, aminomethyl substituents with amine pK(a)'s > 7 accelera

226 ferase inhibitors, we have synthesized three aminomethyl-substituted O(6)-benzylguanines and the thre

227 ituted analogs structurally derived from the aminomethyl-substituted pyrazolo[1,5- a]pyridine lead co

228 Here, we describe a series of aminomethyl-substituted salicylaldehydes that target a f

229 h interfering with binding, whereas the meta-aminomethyl substitution allows an interaction of the am

230 feature of this new class of ligands is a 2-aminomethyl-trans-cyclopropyl side chain attached to a s

231 The heterocyclic beta-aminomethyl vinyl sulfone RA-0002034 (1a) is a potent ir