ライフサイエンスコーパス: amoeba

1 at is coassembled with Mimivirus in the host amoeba.

2 t in the differentiation program of a social amoeba.

3 travacuolar proliferation in macrophages and amoeba.

4 vives in mammals, arthropods, and freshwater amoeba.

5 is thought to promote transmission to a new amoeba.

6 nd late phases of erythrophagocytosis by the amoeba.

7 es such as nonseed plants, algae, fungi, and amoeba.

8 amoeba sori, and disseminates along with the amoeba.

9 en's long term intracellular survival in the amoeba.

10 nt in an attempt to reflect the situation in amoeba.

11 had not been tested before in more than one amoeba.

12 ases in viroids to 670 billion bases in some amoebas.

13 fungi (16 species), plants (6), diatoms (1), amoebas (2), protists (1) and animals (17).

14 AMOEBA, a second-generation force field, was chosen as i

15 tions of three dimorphic fungi with the soil amoeba Acanthameobae castellanii.

16 cessing of L. pneumophila by the free-living amoeba Acanthamoeba castellanii shows many similarities

17 as unable to multiply within the free-living amoeba Acanthamoeba castellanii yet was able to kill HL-

18 ffect on intracellular multiplication in the amoeba Acanthamoeba castellanii, indicating that certain

19 In the small, free-living amoeba Acanthamoeba castellanii, rRNA transcription requ

20 umophila genes necessary for survival in the amoeba Acanthamoeba castellanii.

21 a potential protozoan host, the water-borne amoeba Acanthamoeba castellanii.

22 ncystment phenotype (REP) in the free-living amoeba, Acanthamoeba castellanii.

23 uscle actin filaments (Kd = 0.5 microM) than amoeba actin filaments (Kd = 5 microM) even though the a

24 = 0.03 microM-1 s-1) to and dissociates from amoeba actin filaments in a simple bimolecular reaction,

25 ibits TH-2/3 binding to muscle actin but not amoeba actin filaments.

26 1 microM, for Acanthamoeba profilins binding amoeba actin monomers with bound Mg-ATP.

27 o-cultivated bacteria resemble arthropod- or amoeba-adapted Francisella is unknown.

28 that mannose-based saccharides which inhibit amoeba adhesion to corneal epithelial cells were also po

29 in vacuoles isolated from P2X(A)R knock-out amoeba and ablated in cells devoid of P2XRs.

30 ion that resulted in loss of infectivity for amoeba and HeLa cells and loss of Dot/Icm T4SS-mediated

31 the ankB null mutant in proliferation within amoeba and human cells is rescued by supplementation of

32 la pneumophila proliferates in environmental amoeba and human cells within the Legionella-containing

33 Following Ers treatment entry into amoeba and macrophage hosts does not require dotA, which

34 required for proper intracellular growth in amoeba and macrophage hosts.

35 hat function in the entry of Legionella into amoeba and macrophage hosts.

36 us that translocates bacterial proteins into amoeba and macrophage hosts.

37 Identification of these amoeba and mycobacteria strains indicated that the main

38 a is an intracellular pathogen of freshwater amoeba and of alveolar macrophages in human hosts.

39 ber of ADF/cofilin family, with filaments of amoeba and rabbit skeletal muscle actin.

40 Here we describe such a screen in a social amoeba and show that cheating is multifaceted by reveali

41 shed a model predator-prey system using this amoeba and Synechococcus elongatus PCC 7942.

42 uding chemical reactions, metal rust, yeast, amoeba and the heart and brain.

43 lution between bacterial husbandry in social amoebas and fungus farming in social insects makes sense

44 ve evolved mechanisms that are used to enter amoebas and human macrophages.

45 Upon entry of Legionella pneumophila into amoebas and macrophages, host-mediated farnesylation of

46 hing animals such as amphioxus, sea anemone, amoebas and Trichoplax, and in plants and algae.

47 nst four different taxa: insects, nematodes, amoeba, and mammalian macrophages.

48 Understanding why organisms as different as amoebas, ants, and birds cooperate remains an important

49 Free-living amoebas are thought to serve as a reservoir for Legionel

50 By using survival in amoeba as a selection, we have isolated mutant strains w

51 potential role of an L. pneumophila-infected amoeba as an infectious particle in replicative L. pneum

52 Recently, another type of free-living amoeba, Balamuthia mandrillaris, has been shown to cause

53 In some cases amoebas breach the mucosal barrier and travel through th

54 n myosin heavy chain kinases (MHCKs) in this amoeba but that has a completely novel domain organizati

55 g the underlying in situ metabolism for this amoeba but the potential exists to exploit differentiall

56 ows that B. bronchiseptica not only inhabits amoebas but can persist and multiply through the social

57 ence of surface antibodies specific for this amoeba by immunofluorescence.

58 evels of resistance to, and survival within, amoeba by these bacteria and their known virulence mutan

59 This suggests that the amoeba catecholamine receptor functions downstream of th

60 s considerably delayed in both mammalian and amoeba cells.

61 ancelets, insects, nematodes, fungi, plants, amoebas, ciliates, and excavates spontaneously and rapid

62 linical microbiology laboratories (including amoeba co-culture and shell-vial culture) and through th

63 was isolated from an environmental sample by amoeba coculture.

64 On food depletion, Dictyostelium discoideum amoebas collect into aggregates, which first transform i

65 Dictyostelium discoideum amoebas coordinate aggregation and morphogenesis by secr

66 AMOEBA correctly predicted over 80% of the observed NOEs

67 saE, PsaK1, and PsaK2 are synthesized in the amoeba cytoplasm and traffic into CRs, where they assemb

68 croscopy shows that the endosymbiont ingests amoeba cytoplasm, a novel form of endosymbiont-host comm

69 nt virus particles, Sputnik 2 particles, and amoeba cytoplasm.

70 and phagocytosis of yeast cells resulted in amoeba death and fungal growth.

71 Cytokinesis in animals, fungi, and amoebas depends on the constriction of a contractile rin

72 canthamoeba (genotype T4) or stimulated with amoeba-derived cell-free conditioned medium.

73 From the timing of amoeba development to the maintenance of stem cell pluri

74 The social amoebas (Dictyostelia) display conditional multicellular

75 ent organisms, such as humans and the social amoeba Dictyostelium (Dd).

76 al. (2016) identified in cells of the social amoeba Dictyostelium a G protein-coupled receptor (GPCR)

77 on after fertilization of an egg, the social amoeba Dictyostelium achieves multicellularity by the ag

78 review addresses these issues for the social amoeba Dictyostelium and highlights some of the organism

79 In the social amoeba Dictyostelium and probably many other unicellular

80 hich L. pneumophila is grown within the soil amoeba Dictyostelium discoideum and how D. discoideum ge

81 predator-prey association between the social amoeba Dictyostelium discoideum and the free soil living

82 Farmer clones of the social amoeba Dictyostelium discoideum carry bacteria to seed o

83 The social amoeba Dictyostelium discoideum diverged from the line l

84 The amoeba Dictyostelium discoideum expresses a simple compl

85 The amoeba Dictyostelium discoideum feeds on, and is coloniz

86 Here we show that the social amoeba Dictyostelium discoideum has a primitive farming

87 The life cycle of the social amoeba Dictyostelium discoideum includes a multicellular

88 The social amoeba Dictyostelium discoideum integrates into a multic

89 starvation-induced aggregation of the social amoeba Dictyostelium discoideum into a multicellular slu

90 The microbial soil amoeba Dictyostelium discoideum is a model system for th

91 The social amoeba Dictyostelium discoideum is a professional phagoc

92 The social amoeba Dictyostelium discoideum is a widely used model o

93 The genome of the social amoeba Dictyostelium discoideum is known to have a very

94 f the multicellular slug stage of the social amoeba Dictyostelium discoideum produce ETs upon stimula

95 New research indicates that the social amoeba Dictyostelium discoideum recognizes distinctions

96 ow here that dedifferentiation in the social amoeba Dictyostelium discoideum relies on a sequence of

97 Experiments on the social amoeba Dictyostelium discoideum show that the origins of

98 ria's host is a "farmer" clone of the social amoeba Dictyostelium discoideum that carries and dispers

99 with chemical mutagenesis in the social soil amoeba Dictyostelium discoideum Through genome sequencin

100 The social amoeba Dictyostelium discoideum was selected for functio

101 Using the amoeba Dictyostelium discoideum, a model system for the

102 kly related gene in the genome of the social amoeba Dictyostelium discoideum, and show, with the use

103 In many systems, including the social amoeba Dictyostelium discoideum, development is often ma

104 tingly some eukaryotes, including the social amoeba Dictyostelium discoideum, encode both a class I a

105 In the social amoeba Dictyostelium discoideum, four signaling pathways

106 ular act of cooperation occurs in the social amoeba Dictyostelium discoideum, in which some cells die

107 In the social amoeba Dictyostelium discoideum, starvation-triggered mu

108 involved in cheating behaviors in the social amoeba Dictyostelium discoideum, testing whether these g

109 o regulate spore encapsulation in the social amoeba Dictyostelium discoideum, the metabolic profile a

110 Using the social amoeba Dictyostelium discoideum, we provide a possible e

111 composition can be manipulated in the social amoeba Dictyostelium discoideum, which allows us to test

112 thailandensis to predation by the phagocytic amoeba Dictyostelium discoideum.

113 for extracting DNA from cells of the social amoeba Dictyostelium discoideum.

114 model organism database (MOD) for the social amoeba Dictyostelium discoideum.

115 gus Ustilago maydis and spores of the social amoeba Dictyostelium discoideum.

116 metal efflux or uptake systems in the social amoeba Dictyostelium discoideum.

117 isseminate via the complex life cycle of the amoeba Dictyostelium discoideum.

118 he illusion of social cheating in the social amoeba Dictyostelium discoideum.

119 icellularity is mainly studied in the social amoeba Dictyostelium discoideum.

120 One such system is represented by the social amoeba Dictyostelium discoideum.

121 ffraction experiments on single cells of the amoeba Dictyostelium discoideum.

122 s the model organism database for the social amoeba Dictyostelium discoideum.

123 e, we confirm this prediction for the social amoeba Dictyostelium discoideum; relatedness in natural

124 conventional myosin 7 (DdMyo7) in the social amoeba Dictyostelium However, the exact roles of these M

125 Here we show that the social amoeba Dictyostelium purpureum prefers to form groups wi

126 In live cells of the soil amoeba Dictyostelium that were expressing GFP-ABD, the t

127 IFalpha-type PHDs is expressed in the social amoeba Dictyostelium where it also exhibits characterist

128 In the social amoeba Dictyostelium, a terminal step in development is

129 ates multicellular development of the social amoeba Dictyostelium, suggesting it may serve as an impo

130 similar modification is found in the social amoeba Dictyostelium, where it regulates SCF assembly an

131 A primary example is the social amoeba Dictyostelium, which migrates to the source of tr

132 mes, and the contractile vacuole (CV) of the amoeba Dictyostelium.

133 trigger the rapid sporulation of the social amoeba Dictyostelium.

134 The social amoeba, Dictyostelium discoideum, is known to use peptid

135 The social amoeba, Dictyostelium discoideum, is widely used as a si

136 n forces measured in chemotaxing unicellular amoeba, Dictyostelium discoideum.

137 ices formed during development of the social amoeba, Dictyostelium discoideum.

138 cm mutants following incubation in water and amoeba encystment and was required for delay of phagosom

139 mined the effects of incubation in water and amoeba encystment on L. pneumophila strain JR32 and null

140 Amoeba encystment was inhibited by addition of beta(1)-a

141 The cysteine proteinase-deficient amoeba failed to induce intestinal epithelial cell produ

142 Unlike bacteria that serve as an amoeba food source, B. bronchiseptica evades amoeba pred

143 evades amoeba predation, survives within the amoeba for extended periods of time, incorporates itself

144 septica continues to be transferred with the amoeba for months, through multiple life cycles of amoeb

145 multipole refinement method assisted by the AMOEBA force field for macromolecular crystallography.

146 pole electrostatics model implemented in the AMOEBA force field is applicable and informative for cry

147 ), dead-end elimination with the polarizable AMOEBA force field lowered Rfree by 2.8-26.7% and improv

148 ASA.S1 was obtained from single amoeba, from cultures of all known 18S rDNA genotypes, a

149 cytokinesis in cells with contractile rings (amoebas, fungi, and animals) depends on shared molecular

150 exons and 5 introns that span 3.6 kb of the amoeba genome and that MBP cDNA codes for a precursor pr

151 ly and annotation of three highly repetitive amoeba genomes, Entamoeba histolytica, Entamoeba dispar,

152 ing status previously has been attributed to amoeba genotype, but the role of bacterial partners in i

153 30 % of actophorin is phosphorylated in live amoebas grown in suspension culture.

154 To explore whether amoeba-grown L. pneumophila differs from BCYE-grown L. p

155 Although amoeba-grown L. pneumophila displays enhanced entry into

156 In addition, amoeba-grown L. pneumophila displays increased replicati

157 Entry of amoeba-grown L. pneumophila into monocytes occurred more

158 Furthermore, amoeba-grown M. avium was also more virulent in the beig

159 es of the coprophilic, fruiting body-forming amoeba Guttulinopsis vulgaris and its non-fruiting relat

160 This amoeba had previously been found only in environmental s

161 ing during the first 24h of infection of the amoeba Hartmanella vermiformis.

162 infection was investigated in vivo with the amoeba Hartmannella vermiformis, a natural reservoir of

163 mophila which have reduced virulence for the amoeba Hartmannella vermiformis.

164 The finding that this amoeba has caused infection in some healthy children has

165 ven discovery of giant DNA viruses infecting amoebas has triggered an intense debate about the origin

166 s problem, we have isolated a heterolobosean amoeba, HGG1, that grazes upon unicellular and filamento

167 However, in the amoeba host a mutant lacking both sidJ and sdjA does not

168 rium finds itself in a hot mammalian or cool amoeba host environment.

169 it because it can confer an advantage to the amoeba host when grown in food-limiting conditions.

170 relationship between Perkinsela sp. and its amoeba host, and provide a foundation for understanding

171 and multiply through the social stage of an amoeba host, Dictyostelium discoideum.

172 enera (Legionella and mycobacteria), and two amoeba hosts (Acanthamoeba spp. and Hartmanella vermifor

173 ificant growth defect in both macrophage and amoeba hosts, but an sdjA mutant is detectably defective

174 Acanthamoeba amoeba in 16 solutions (80 %) collected from 12 patients

175 l cell apoptosis occurred in the vicinity of amoeba in histological specimens.

176 erates within a diverse range of free-living amoeba in the environment, but upon transmission to huma

177 poptosis occurred rapidly on co-culture with amoeba in vitro as measured by annexin positivity, DNA d

178 during Legionnaires' disease and invasion of amoebas in the environment.

179 revealed independent origins of filopodiated amoebas in two lineages, one related to fungi and the ot

180 Diverse soil amoebas including Dictyostelium and Acanthamoeba can hos

181 eukocytes (PMNs) or Dictyostelium discoideum amoeba induced formation of filamentous actin.

182 hesion of the parasites to host cells or the amoeba-induced CPE.

183 amoeba to host cells is also an inhibitor of amoeba-induced CPE.

184 thelial cells were also potent inhibitors of amoeba-induced CPE.

185 oeba to host cells is a prerequisite for the amoeba-induced cytolysis of target cells and have implic

186 bohydrate binding properties and the role in amoeba-induced cytopathic effect (CPE).

187 Amoebas infected with mimivirus were disrupted at sequen

188 of a new giant virus that is related to the amoeba-infecting pathogen Marseillevirus was recovered f

189 The revival of such an ancestral amoeba-infecting virus used as a safe indicator of the p

190 isinfected biofilms was 1-2 times higher and amoeba infectivity was 2-29 times lower than that from u

191 gnificant advantages for the study of fungus-amoeba interactions.

192 The transition from spore to amoeba is accompanied by developmentally regulated chang

193 ough the internal environment of free-living amoebas is similar in many ways to that of mammalian mac

194 lular pathogenic strategy in macrophages and amoebas is similar, leading to the proposal that it orig

195 yostelium discoideum, a soil-dwelling social amoeba, is a model for the study of numerous biological

196 TS region was performed in order to identify amoeba isolates, and the presence of Legionella pneumoph

197 such as Dictyostelium discoideum This social amoeba kills bacteria via phagocytosis for nutrient acqu

198 ogical systems such as dictyostelids, social amoeba known to form multicellular aggregates observed a

199 a "remembering" prior nutritional status and amoeba "learning" to anticipate future environmental con

200 Sugar inhibition assays revealed that the amoeba lectin has the highest affinity for alpha-Man and

201 s a major virulence protein suggest that the amoeba lectin has the potential to serve as a marker of

202 We characterized the amoeba lectin with respect to its carbohydrate binding p

203 produce flagellated cells, but many produce amoeba-like cells.

204 At low densities, NPCs moved randomly in an amoeba-like fashion.

205 ctor alpha, LCs showed amplified dSEARCH and amoeba-like lateral migration between keratinocytes.

206 constantly crawled around hair follicles via amoeba-like movements with a mean velocity of 1.0+/-0.4

207 ad and decaying tail and moving and dividing amoeba-like structures with sharp edges.

208 tion defects in Hartmannella vermiformis, an amoeba linked to hospital outbreaks of Legionella pneumo

209 In highly polarized Dictyostelium discoideum amoebas, membrane-associated betagamma subunits of heter

210 roM) even though the affinity for muscle and amoeba Mg-ADP-actin monomers (Kd = 0.1 microM) is the sa

211 s isolated with enhanced virulence in a soil amoeba model that nevertheless exhibits dramatically red

212 e (MIHCK) phosphorylates the heavy chains of amoeba myosins I, increasing their actin-activated ATPas

213 ith a Delta24 sterol reductase from the soil amoeba Naegleria gruberi.

214 at T2S is also critical for infection of the amoeba Naegleria lovaniensis.

215 nella, mycobacteria, P. aeruginosa, and both amoebas naturally colonized the six SDSs, but L. pneumop

216 ogy and immunohistochemistry for free-living amoebas on the brain biopsy tissue were positive.

217 The amoeba originally identified as Sappinia diploidea was i

218 The amoeba Paulinella chromatophora contains nascent photosy

219 The photosynthetic amoeba Paulinella chromatophora represents a unique mode

220 perspective on this issue is provided by the amoeba Paulinella chromatophora, which contains photosyn

221 ithemia turgida and the endosymbionts of the amoeba Paulinella chromatophora.

222 sing molecular dynamics simulations with the AMOEBA polarizable force field and perturbation techniqu

223 (LDE), using atomistic simulations with the AMOEBA polarizable force field.

224 amoeba food source, B. bronchiseptica evades amoeba predation, survives within the amoeba for extende

225 food-rich conditions, Burkholderia-colonized amoebas produce fewer spores than uncolonized counterpar

226 is about 10 microM proline decamer units for amoeba profilin and 20-30 microM for human profilin.

227 led X-bacteria), present in the xD strain of Amoeba proteus as required cell components, synthesize a

228 ere we show that a locus ('Tgr') of a social amoeba represents a polychromatic greenbeard.

229 Among these amoeba resistant bacteria are numerous members of the ge

230 the role that mannose stimulation has in the amoeba's growth, secreted products, and ability to desqu

231 and 0.003%) with hydrogen peroxide (3%) and amoeba saline controls.

232 cipients remained susceptible as measured by amoeba score and culture, whereas CBA BM --> B6 recipien

233 L-10(-/-)Rag2(-/-) mice exhibited diminished amoeba scores and culture rates vs IL-10(-/-) mice, indi

234 --> IL-10(-/-) recipients, exhibited higher amoeba scores than their wild-type controls.

235 eriods of time, incorporates itself into the amoeba sori, and disseminates along with the amoeba.

236 However, studies in amoeba suggest that P2X receptors are also present intra

237 the ability of Burkholderia to colonize new amoebas, suggests a mixed mode of symbiont transmission.

238 The amoeba surface lectin that binds mucin is presumed to co

239 Amoeba survival was calculated using the most probable n

240 Both fusaria and amoeba tended to be observed in discrete regions of the

241 telium discoideum farming symbiosis, certain amoebas (termed "farmers") stably associate with bacteri

242 Dictyostelium is a social amoeba that undergoes a basic developmental program, and

243 Dictyostelium discoideum are social amoebas that propagate as unicellular organisms but aggr

244 Within macrophages and amoeba, the Legionella-containing vacuole (LCV) membrane

245 n relationships, but the general response of amoeba to bacteria is not well understood.

246 (GlcNAc) which does not inhibit adhesion of amoeba to host cells is also an inhibitor of amoeba-indu

247 ryotic hosts that extends from single-celled amoeba to mammals.

248 ic flagellated bacterivores and filopodiated amoebas to cell-walled osmotrophic parasites and saprotr

249 In Dictyostelium (a social amoeba), Toxoplasma gondii (the agent for human toxoplas

250 atecholamine binding sites on the surface of amoeba trophozoites was confirmed using radiolabeled cat

251 amoeba castellanii and reversion of cysts to amoeba trophozoites, dotA and dotB mutants exhibited int

252 sity where the buoyant force should push the amoeba upward.

253 mal RNA (ssrRNA) gene from the naked, marine amoeba, Vannella anglica (subclass Gymnamoebia), was det

254 The affinity-purified protein of the amoeba was shown to bind specifically to mannose-BSA.

255 a previously unknown cell type in the social amoeba, which appears to provide detoxification and immu

256 sin (DdMVII) in the Dictyostelium discoideum amoeba, which is a model for phagocytosis, is reported h

257 fore bacteria infected humans, they infected amoebas, which remain a potentially important reservoir

258 oeba castellanii is a ubiquitous free-living amoeba with a worldwide distribution that can occasional

259 itis was reported that was caused by another amoeba with morphological features suggestive of Sappini