ライフサイエンスコーパス: amplified region

1 ks from progressing beyond the normal 100-kb amplified region.

2 ing to false-positive results in copy number-amplified regions.

3 hybridization (array CGH) to map the minimal amplified regions.

4 sequence tag were located in the two common amplified regions.

5 ngth polymorphism (RFLP) patterns within the amplified regions.

6 We have identified eight amplified regions (1q31-32, 2p23-24, 7q21, 7q31, 9q22, 9

7 ts were transitions occurring throughout the amplified region, although frameshifts and transversions

8 ization (array CGH) to define minimum common amplified regions and then used expression analysis to i

9 for driver genes within large deletions and amplified regions, and identifies therapeutic targets.

10 906 and D11S937, at the telomeric end of the amplified region at 11q13, and found that it was amplifi

11 Positional cloning efforts directed at the amplified region at 3q26-q27 identified three highly ove

12 of CKS1B, a gene mapping within a minimally amplified region between 153 to 154 Mb of chromosome 1q2

13 All the DMs consisted of the core amplified region combined with additional DNA fragments.

14 More importantly, by honing in on minimally amplified regions containing three or fewer genes, we id

15 (ddPCR) of mouse p-TGCs, we identified five amplified regions, each containing a gene family known t

16 o the general isolation of gene families and amplified region from genomic DNAs.

17 sess the performance of HATS using simulated amplified regions generated from varying copy number and

18 n cancers compared to other genes within the amplified region, implicating RAB25 as a driving event i

19 hybridization analysis to identify possible amplified regions (implying amplified/overexpressed gene

20 d CpG islands and the characterization of an amplified region in a breast tumor that spanned <230 kb

21 c single-nucleotide polymorphisms within the amplified regions in a subsequent LDR.

22 The most frequently amplified regions in AMs occurred at 11q13 (47%), 22q11-

23 Commonly amplified regions in breast cancer, chromosomes 8q and 1

24 -24, which is one of the three most commonly amplified regions in head and neck squamous cell carcino

25 eakpoints that coincide with the four highly amplified regions in MCF-7 detected by array CGH located

26 Although amplified regions in tumor DNA may exceed several megaba

27 The amplified region includes genes for cyclin D1, hst-1, in

28 al env sequences, followed by cloning of the amplified regions into expression vectors.

29 e samples and found that the most frequently amplified region is at chromosome 7p11.2.

30 We identified 49 minimal commonly amplified regions (MCRs) that included known (1q, 8q24,

31 The identification of amplified regions might have both prognostic and therape

32 l gains and losses were not observed, a 1-Mb amplified region of 7q34 was detected in multiple patien

33 elanoma model to test genes in a recurrently amplified region of chromosome 1 for the ability to coop

34 Cloning experiments using an amplified region of the 16S rRNA that contains the varia

35 number and expression of all genes within an amplified region of the genome have not been performed.

36 npoint driver genes within large recurrently amplified regions of DNA.

37 Cloning of amplified regions of the 16S rRNA genes and subsequent s

38 nd erd pedigrees were sought by digestion of amplified regions of the CFRDSP gene with different rest

39 were deduced from polymerase chain reaction-amplified regions of the corresponding genes and subsequ

40 ly, ERDS accommodates both unique and highly amplified regions of the genome and does so without requ

41 Characterization of amplified regions of the genome in breast cancer has led

42 ven protein genes or are introduced from PCR-amplified regions of the JEV SA14-14-2 genome.

43 Mapping of the commonly amplified region revealed there are three genes in the c

44 Furthermore, Sequence Characterized Amplified Region (SCAR) markers were designed envisionin

45 A method based on Sequence-Characterized Amplified Regions (SCARs) was developed to detect the pr

46 om all 44 isolates, while eight primer pairs amplified regions that were polymorphic between isolates

47 mined, which allowed us to finalize the core-amplified region to <300 kb.

48 Detailed mapping of the amplified region using molecular cytogenetics, positiona

49 tative measurement of DNA copy number across amplified regions using array comparative genomic hybrid

50 normal metaphase spreads, confirmed that the amplified region was derived from sequences from 9q34.

51 The maximum amplified region was narrowed to 3-6 Mb by multicolor FI

52 Expression of genes in the amplified regions was significantly elevated.

53 itate the identification of genes mapping to amplified regions, we have used a technique based on the

54 Amplified regions without known oncogenes were enriched