ライフサイエンスコーパス: an evolutionarily conserved

1 An evolutionarily conserved 12-bp cis-regulatory motif t

2 inase, Lats1/2, on multiple sites, including an evolutionarily conserved 14-3-3-binding site whose ph

3 Eri1 is an evolutionarily conserved 3'-5' exoribonuclease that p

4 An evolutionarily conserved 3-hydroxy butyrate dehydroge

5 iruses, the NP of influenza B virus contains an evolutionarily conserved 50-amino-acid N-terminal ext

6 ene 3) is an imprinted gene localized within an evolutionarily conserved 500-kb domain in human chrom

7 article (cpSRP) is a heterodimer composed of an evolutionarily conserved 54-kDa GTPase (cpSRP54) and

8 Our findings highlight an evolutionarily conserved activation mechanism of GPHR

9 After biosynthesis, an evolutionarily conserved acyl chain remodeling proces

10 We discovered an evolutionarily conserved allosteric restraint mechani

11 a methyl group to adenosine N(6) (m(6)A) is an evolutionarily conserved and common RNA modification

12 alyze these modifications, which are part of an evolutionarily conserved and complex tubulin code tha

13 ese results reveal a crucial role of Tid1 as an evolutionarily conserved and essential mediator of ca

14 at cytoplasmic and organelle transport plays an evolutionarily conserved and functionally important r

15 Through RNAi screening, we identify an evolutionarily conserved and interferon-independent r

16 ORC1), defined by the presence of Raptor, is an evolutionarily conserved and nutrient-sensitive regul

17 poor follicular development and demonstrated an evolutionarily conserved and ovary-specific role of N

18 re we examine the in vivo function of SCYL2, an evolutionarily conserved and ubiquitously expressed p

19 Here, we show that CTRP4 is an evolutionarily conserved, approximately 34-kDa secret

20 Thus, our studies reveal an evolutionarily conserved archaic embryonic program in

21 These data reveal an evolutionarily conserved ascending system that gates

22 Together, these results identify an evolutionarily conserved association between the fish

23 vation of these host DNA sensing pathways is an evolutionarily conserved bacterial adaptation.

24 Sleep is an evolutionarily conserved behavioral state whose regul

25 activity of soluble adenylyl cyclase (sAC), an evolutionarily conserved bicarbonate sensor.

26 Together, our data point to an evolutionarily conserved, bifunctional role for SSS a

27 Lhx8_enh1 contained an evolutionarily conserved binding site for lymphoid en

28 on is observed for SNP rs17023457 located in an evolutionarily conserved binding site for the transcr

29 physically associating with CCT, suggesting an evolutionarily conserved biological function.

30 h processing in the human auditory cortex-as an evolutionarily conserved biological process.

31 The hypothalamus is an evolutionarily conserved brain structure that regulat

32 over and activity are tightly linked through an evolutionarily conserved C-terminal instability eleme

33 Here we describe an evolutionarily conserved C. elegans protein, VPS-50,

34 cological tools to demonstrate that TMEM16A, an evolutionarily conserved calcium-activated chloride c

35 Autophagy is an evolutionarily conserved catabolic mechanism that rel

36 Autophagy is an evolutionarily conserved catabolic process that recyc

37 Eya1 has an evolutionarily conserved CDC4 phosphodegron (CPD) sig

38 aenopsis cyclin-dependent kinase A (CDKA) is an evolutionarily conserved CDK.

39 Endoplasmic reticulum stress is an evolutionarily conserved cell stress response associa

40 Autophagy is an evolutionarily conserved cellular homeostatic pathway

41 Autophagy is an evolutionarily conserved cellular process controlled

42 ndoplasmic reticulum (ER) stress response is an evolutionarily conserved cellular signaling cascade t

43 g studies further support the model in which an evolutionarily conserved central cleft is the surface

44 Taken together, our results show an evolutionarily conserved cerebral distribution of 5hm

45 be an exception and suggests the presence of an evolutionarily conserved chemosensory cue within the

46 ing families across tetrapods to reconstruct an evolutionarily conserved co-expression network.

47 Mediator is an evolutionarily conserved coactivator complex essentia

48 Aggression is an evolutionarily conserved complex behavior essential f

49 The INO80 chromatin remodeling complex is an evolutionarily conserved complex involved in diverse

50 ticulum (ER)-membrane protein complex (EMC), an evolutionarily conserved complex that has been propos

51 Furthermore, an evolutionarily-conserved conformational link from the

52 The ECE1 endothelial enhancer also contains an evolutionarily-conserved, consensus SOX binding site,

53 d structural data indicating that they share an evolutionarily conserved core of ribosomal RNA and pr

54 Commencing at an evolutionarily conserved CpG (CpG -41), CCR5 cis-regi

55 infection with multiple PV types, suggesting an evolutionarily conserved critical step in infectious

56 C, which determined the base substitution of an evolutionarily conserved Cys residue for an Arg in th

57 intramolecular automethylation reactions at an evolutionarily conserved cysteine residue in the acti

58 The formation of WNK bodies requires an evolutionarily conserved cysteine-rich hydrophobic mo

59 cuitry underlying the execution of freezing, an evolutionarily conserved defensive behaviour, which i

60 Our study reveals an evolutionarily conserved deficiency of the Sec61/SecY

61 ent receptor potential A1 (TRPA1) channel is an evolutionarily conserved detector of temperature and

62 crystallographic and biochemical analyses of an evolutionarily conserved deubiquitinase, USP12, which

63 These results show that an evolutionarily conserved developmental pathway regula

64 nterdigitated growth of neighboring cells is an evolutionarily conserved developmental strategy.

65 al enhancer activator domain) proteins share an evolutionarily conserved DNA-binding TEA domain, whic

66 hus, our analyses identify the LLM domain as an evolutionarily conserved domain that determines B-cla

67 he T-box family of transcription factors and an evolutionarily conserved dosage-sensitive regulator o

68 Macroautophagy is an evolutionarily conserved dynamic pathway that functio

69 includes suppression of immune responses via an evolutionarily conserved effector target, but by reco

70 Epsin is an evolutionarily conserved endocytic clathrin adaptor w

71 VAP (VAPA and VAPB) is an evolutionarily conserved endoplasmic reticulum (ER)-a

72 onal AMPK-activated protein kinase (AMPK) is an evolutionarily conserved energy sensor that plays an

73 Using bioinformatics, we characterized an evolutionarily conserved enhancer element present in

74 We conclude that HERV-K ENV dictates an evolutionarily conserved entry pathway and that the r

75 Specific deletion or mutation of an evolutionarily conserved ERF-associated amphiphilic r

76 Novelty preference (NP) is an evolutionarily conserved, essential survival mechanis

77 We show that this interaction is mediated by an evolutionarily conserved ETGE motif on CDK20.

78 entous fungi, which are communicated through an evolutionarily conserved eukaryotic stress response p

79 (TIR) motif-containing protein 1 (SARM1) is an evolutionarily conserved executioner of this degenera

80 Consistent with an evolutionarily conserved extra-mitochondrial function

81 Here we identify an evolutionarily conserved factor, BRWD2/PHIP, which co

82 -2)-associated athanogene (BAG) proteins are an evolutionarily conserved family of co-chaperones that

83 d multivesicular body proteins (Chmp1-7) are an evolutionarily conserved family of cytosolic proteins

84 Serum amyloid A (SAA) represents an evolutionarily conserved family of inflammatory acute

85 produce small molecules called ascarosides, an evolutionarily conserved family of nematode pheromone

86 Here, we report that ascarosides, an evolutionarily conserved family of nematode pheromone

87 The aurora kinases (AURKs) comprise an evolutionarily conserved family of serine/threonine k

88 APP belongs to an evolutionarily conserved family of transmembrane prot

89 one H3 lysine 4 monomethylation (H3K4me1) is an evolutionarily conserved feature of enhancer chromati

90 ronal death, indicating these activities are an evolutionarily conserved feature of SARM1 function.

91 The formation of branched lariat RNA is an evolutionarily conserved feature of splicing reaction

92 ation of B cells around splenic vasculature, an evolutionarily conserved feature since the spleen's e

93 These comparisons reveal an evolutionarily conserved force balance between the ca

94 We further identified an evolutionarily conserved fragment near the insertion

95 AMP-activated kinase (AMPK) is an evolutionarily conserved fuel-sensing enzyme and a ke

96 EAG2 (Ether-a-go-go 2) potassium channel has an evolutionarily conserved function for promoting brain

97 Pol-II-associated factor 1 (PAF1) possesses an evolutionarily conserved function in metazoans in the

98 resents a positive FTi regulator that shares an evolutionarily conserved function with SOC1 and may n

99 RB control of cell polarity may be an evolutionarily conserved function, with important imp

100 s are conserved among great apes, suggesting an evolutionarily conserved function.

101 Our experiments reveal an evolutionarily conserved GABA synthesis pathway media

102 An evolutionarily conserved Galpha-GPR-1/2(Pins/LGN)-LIN

103 -loop-helix [bHLH], and WD40) genes comprise an evolutionarily conserved gene cassette that regulates

104 FoxA, an evolutionarily conserved gene involved in the develop

105 Makorin-2 (Mkrn2) is an evolutionarily conserved gene whose biological functi

106 Thus, we have identified an evolutionarily conserved gene, stum, which is require

107 a second PD-associated gene, RAB7L1, within an evolutionarily conserved genetic module in diverse ce

108 Bcl-2-associated athanogene (BAG) family is an evolutionarily conserved group of cochaperones that m

109 ires the precisely coordinated regulation of an evolutionarily conserved group of signaling pathways.

110 ns unveil an unprecedented regulatory use of an evolutionarily conserved heat shock protein and prese

111 FACT (facilitates chromatin transcription), an evolutionarily conserved histone chaperone involved i

112 Autophagy, an evolutionarily conserved homeostasis process regulati

113 n(IV) oxochloride-derived cluster that binds an evolutionarily conserved IDR within the metazoan TFII

114 Altogether, these data indicate CD39 as an evolutionarily conserved inducible protective pathway

115 poptosis-stimulating protein of p53 (iASPP), an evolutionarily conserved inhibitor of p53, caused by

116 Finally, we propose an evolutionarily conserved interaction between Foxh1 an

117 Our study underscores an evolutionarily conserved interaction between lentivir

118 We identify an evolutionarily conserved interaction surface formed b

119 cooperatively to the 40 S subunit, revealing an evolutionarily conserved interaction.

120 Autophagy, an evolutionarily conserved intracellular catabolic proc

121 Autophagy is an evolutionarily conserved intracellular degradation/re

122 A point mutation in an evolutionarily conserved lysine-rich domain encoded b

123 arrel proteins into membranes is mediated by an evolutionarily conserved machine.

124 tholog of Myoblast City, DOCK1, functions in an evolutionarily conserved manner to promote myoblast f

125 te that emotional contagion is prevented, in an evolutionarily conserved manner, by the stress of a s

126 PARs are present at the hair cell synapse in an evolutionarily conserved manner.

127 d associates with LINC complex components in an evolutionarily conserved manner.

128 l leucine zipper kinase (DLK)-Jnk pathway is an evolutionarily conserved MAPK signaling pathway that

129 The target of rapamycin (TOR) kinase is an evolutionarily conserved master regulator that integr

130 t complementary, functions and may represent an evolutionarily conserved means to ensure proper progr

131 stelium and in human neutrophils, suggesting an evolutionarily conserved mechanism for eukaryotic che

132 Alternative polyadenylation (APA) is an evolutionarily conserved mechanism for regulating gen

133 location of pYGSK into flagella and cilia is an evolutionarily conserved mechanism fundamental to the

134 lla suggest that TAG breakdown may represent an evolutionarily conserved mechanism in light-induced s

135 This implies an evolutionarily conserved mechanism leading to this tr

136 tophagy (herein referred to as autophagy) is an evolutionarily conserved mechanism of adaptation to a

137 Our results establish rosette-based CE as an evolutionarily conserved mechanism of nerve cord morp

138 Our results highlight an evolutionarily conserved mechanism of regulated prote

139 an target of rapamycin complex 1 (mTORC1) is an evolutionarily conserved mechanism that controls cell

140 This may represent an evolutionarily conserved mechanism that not only redu

141 Nucleotide excision repair (NER) is an evolutionarily conserved mechanism that processes hel

142 pic heterogeneity within cell populations is an evolutionarily conserved mechanism that underlies pop

143 nslated in response to localized signals, is an evolutionarily conserved mechanism to control protein

144 Nociception is an evolutionarily conserved mechanism to encode and proc

145 , the fetal mammalian brain is equipped with an evolutionarily conserved mechanism well-suited to sup

146 ulation of Yang cycle MTN proteins is likely an evolutionarily conserved mechanism whereby HopAF1 ort

147 We also reveal an evolutionarily conserved mechanism whereby the cell r

148 1 regulates hepcidin gene expression through an evolutionarily conserved mechanism.

149 Based on such an association, we identified an evolutionarily conserved metabolic regulator, Kruppel

150 tion of histone H3K79, which is catalyzed by an evolutionarily conserved methyltransferase, disruptor

151 MicroRNA390 (miR390) is an evolutionarily conserved microRNA that targets the Tr

152 The 5' m7G cap is an evolutionarily conserved modification of eukaryotic m

153 confer diurnal patterns of transcription via an evolutionarily conserved module present in GI and oth

154 tes basic helix-loop-helix (bHLH) factors as an evolutionarily conserved module, but the tissue-speci

155 Chitinase 3-like-1 (Chi3l1) is an evolutionarily conserved moiety that plays a critical

156 lates adipokine secretion and have uncovered an evolutionarily conserved molecular link between intra

157 icient conditions; these promoters contained an evolutionarily conserved motif that we named the low

158 eading to the active site that is blocked by an evolutionarily conserved motif which we term the "DK

159 in Caenorhabditis elegans that acts through an evolutionarily conserved motif, termed ESRE, for etha

160 Autophagy, referring to an evolutionarily conserved, multi-step lysosomal degrad

161 Condensin, an evolutionarily conserved multisubunit protein complex

162 MYC binds WDR5 via an evolutionarily conserved "MYC box IIIb" motif that en

163 er, NP of influenza B viruses (BNP) contains an evolutionarily conserved N-terminal 50-amino-acid ext

164 sophila, suggesting that TGF-beta represents an evolutionarily conserved negative regulator of the im

165 t mediate this allosteric mechanism comprise an evolutionarily conserved network discovered by statis

166 -bridging phenotype arises from mutations in an evolutionarily conserved network of coevolving amino

167 Importantly, miR-K10a taps into an evolutionarily conserved network of miR-142-3p target

168 ase that are connected to the active site by an evolutionarily conserved network of residues (protein

169 or Nkx6.1 interacts with a cis-element (CR2, an evolutionarily conserved non-coding fragment in the s

170 ones are basic nuclear proteins that possess an evolutionarily conserved nucleosome-binding globular

171 Our earlier studies showed that Mge1, an evolutionarily conserved nucleotide exchange factor o

172 regions between LDLR class A repeats contain an evolutionarily conserved O-glycosylation site at posi

173 We identified an evolutionarily conserved octameric sequence, CCCAGCAG

174 e components of the Hippo signaling pathway, an evolutionarily conserved organ growth regulator, modu

175 The cilium is an evolutionarily conserved organelle projecting from th

176 Collectively, this study reveals an evolutionarily conserved paradigm in which the sensor

177 itochondrial fatty acid synthesis (mtFAS) is an evolutionarily conserved pathway essential for the fu

178 An evolutionarily conserved pathway readout is not estab

179 Notch signaling is an evolutionarily conserved pathway that regulates cellu

180 Autophagy is an evolutionarily conserved pathway that transports cyto

181 children with anxiety disorders to identify an evolutionarily conserved pattern of functional connec

182 Thus, PTPRS represents an evolutionarily conserved pDC-specific inhibitory rece

183 ed in colorectal cancer (mcc), which encodes an evolutionarily conserved PDZ domain-containing putati

184 his beneficial effect of H2O2 is mediated by an evolutionarily conserved peroxiredoxin-p38/MAPK signa

185 ation following mitochondrial dysfunction is an evolutionarily conserved phenomenon, and represents a

186 Because PCP is an evolutionarily conserved phenomenon, our study is lik

187 Replication fork reversal is emerging as an evolutionarily conserved physiological response for r

188 Prohibitin-1 (PHB1) is an evolutionarily conserved pleiotropic protein that par

189 associates with DNA polymerase epsilon, via an evolutionarily conserved 'Pol binding module' in Ctf1

190 derstanding of this regulation by describing an evolutionarily conserved post-translational mechanism

191 These RBPs suppress an evolutionarily conserved posttranscriptional regulon

192 equired for viability" (ARV1) gene, encoding an evolutionarily conserved, potential lipid transporter

193 redoxin (Prx) proteins by Oct1 appears to be an evolutionarily conserved process because yeast Oct1 c

194 Autophagy is an evolutionarily conserved process by which long-lived

195 totic cell (AC) clearance (efferocytosis) is an evolutionarily conserved process essential for immune

196 sis in E. histolytica may also shed light on an evolutionarily conserved process for intercellular ex

197 Macroautophagy (hereafter autophagy) is an evolutionarily conserved process in which portions of

198 variation of translation elongation rate is an evolutionarily conserved process leading to the polys

199 Asymmetric division is an evolutionarily conserved process that generates daugh

200 rnover of the 26S proteasome by autophagy is an evolutionarily conserved process that governs cellula

201 Cell-cell fusion is an evolutionarily conserved process that leads to the fo

202 Epithelial wound healing is an evolutionarily conserved process that requires coordi

203 ponse to physiologically relevant stimuli is an evolutionarily conserved process.

204 aises the possibility that danger sensing is an evolutionarily conserved process.

205 Segmentation of the vertebrate hindbrain is an evolutionarily conserved process.

206 er" molecular chaperones may hold the key to an evolutionarily conserved program for management of to

207 oop and disrupts steroid binding, suggesting an evolutionarily conserved property of CBGs.

208 -transcribed genes with nucleoli seems to be an evolutionarily conserved property of the spatial orga

209 Retromer is an evolutionarily conserved protein complex composed of

210 Cohesin is an evolutionarily conserved protein complex that plays a

211 We conclude that Hok1 is part of an evolutionarily conserved protein complex that regulat

212 Our results demonstrate how an evolutionarily conserved protein involved in the regu

213 ase (TSN or Tudor-SN; also known as SND1) is an evolutionarily conserved protein involved in the tran

214 S domain containing protein kinase (Pask) is an evolutionarily conserved protein kinase implicated in

215 Psoralen 4 (Pso4) is an evolutionarily conserved protein that has been implic

216 Ipk2), also known as IP multikinase IPMK, is an evolutionarily conserved protein that initiates produ

217 Ecdysoneless (ECD) is an evolutionarily conserved protein whose germ line dele

218 The synaptonemal complex (SC) is an evolutionarily-conserved protein assembly that holds

219 P1) and that this interaction is mediated by an evolutionarily conserved PXVXL motif in the C-termina

220 The general stress response (GSR) is an evolutionarily conserved rapid and transient transcri

221 via a signalling pathway that has recruited an evolutionarily conserved receptor (Gpr1) and transcri

222 ein-coupled A2a adenosine receptor (A2aR) is an evolutionarily conserved receptor that limits and red

223 Deletion or insertional duplication of an evolutionarily conserved region (ECR) downstream of H

224 o the inter-SH2 (iSH2) domain of p85 through an evolutionarily conserved region located at the C term

225 n, confirmed by 3 orthogonal methods, alters an evolutionarily conserved region of the HMGB3 protein

226 Fzy is an evolutionarily conserved regulator of anaphase promot

227 te-inducible RNA-associated protein-like) is an evolutionarily conserved regulator of cellular proteo

228 The COP9 signalosome (CSN) is an evolutionarily conserved regulator of cullin ring lig

229 Thus, semaphorin 3C/3D signaling is an evolutionarily conserved regulator of ENS development

230 The Salvador-Warts-Hippo (Hippo) pathway is an evolutionarily conserved regulator of organ growth an

231 The Hippo pathway is an evolutionarily conserved regulator of organ size and

232 Dachsous (Dchs), an atypical cadherin, is an evolutionarily conserved regulator of planar cell pol

233 demonstrates how chromatin remodeling within an evolutionarily conserved regulatory element in intron

234 e also present in human heart, indicative of an evolutionarily conserved regulatory mechanism.

235 erved putative enhancer of Dmrt5, suggesting an evolutionarily conserved regulatory relationship betw

236 also showed high ST2 expression, suggesting an evolutionarily conserved requirement for IL-33 in VAT

237 required for anti-RVFV autophagy, revealing an evolutionarily conserved requirement for pattern-reco

238 Finally, we show that an evolutionarily conserved residue in the PLL domain is

239 onclusion, down-regulation of translation is an evolutionarily conserved response to reduced IIS, but

240 Proteasome inhibition elicits an evolutionarily conserved response wherein proteasome

241 We have previously described the presence of an evolutionarily conserved RNA stem-loop structure on t

242 Lin28 is an evolutionarily conserved RNA-binding protein that inh

243 LIN28 is an evolutionarily conserved RNA-binding protein with cri

244 Here, we show that Nanos2, an evolutionarily conserved RNA-binding protein, works w

245 Our results elucidate an evolutionarily conserved role for Lhx9 in Hcrt neuron

246 down experiments in Xenopus laevis confirmed an evolutionarily conserved role for NRIP1 in renal deve

247 Our studies reveal an evolutionarily conserved role for substrate sequences

248 tion zone formation and function, suggesting an evolutionarily conserved role for Tmem231.

249 Nups play an evolutionarily conserved role in gene expression regu

250 These results demonstrate that ADCY1 has an evolutionarily conserved role in hearing and that cAM

251 Our data show that Marf and Mitofusins share an evolutionarily conserved role in mitochondrial transp

252 Finally, we demonstrate that FoxP1 has an evolutionarily conserved role in regulating pathways

253 analyses demonstrate that this protein plays an evolutionarily conserved role in the organization of

254 ase bridges and show that TopBP1/Dpb11 plays an evolutionarily conserved role in their metabolism.

255 We conclude that otoferlin plays an evolutionarily conserved role in vertebrate hearing a

256 The superior colliculus plays an evolutionarily conserved role in visual behaviours, b

257 Taken together, our results establish an evolutionarily conserved role of Coa6 in complex IV a

258 ckdown decreases differentiation, suggesting an evolutionarily conserved role of MUNC lncRNA in myoge

259 Our results reveal an evolutionarily conserved role of NF-kappaB in T cells

260 These findings highlight an evolutionarily conserved role of TOR signaling in SC

261 , SMARCD2 and SMARCD3 paralog family) reveal an evolutionarily conserved role specifically for the SM

262 This activity of Zhp3 suggests an evolutionarily conserved SC-independent strategy for

263 We report here that DLG5 functions as an evolutionarily conserved scaffold and negative regula

264 Many functional RNAs have an evolutionarily conserved secondary structure.

265 These studies have amassed evidence for an evolutionarily conserved secretory program that regul

266 An evolutionarily conserved sequence at the 5' terminus

267 trate that phosphorylation of Dazl by MK2 on an evolutionarily conserved serine residue inhibits its

268 osphorylation and its autophosphorylation at an evolutionarily conserved serine residue near the carb

269 ular elements underlying behavior and reveal an evolutionarily conserved set of diverse neuromodulato

270 The central extended amygdala is an evolutionarily conserved set of interconnected brain

271 is cerana (Ac) and Apis mellifera (Am) share an evolutionarily conserved set of QMP compounds: (E)-9-

272 The Wnt/beta-catenin pathway is an evolutionarily conserved set of signals with critical

273 Notch signaling is an evolutionarily conserved signal transduction pathway

274 for phagolysosomal degradation in activating an evolutionarily conserved signaling cascade, which ens

275 neurons requires different levels of Trim9, an evolutionarily conserved signaling molecule [8-11].

276 Notch1 is an evolutionarily conserved signaling molecule required

277 cription (STAT) pathway is now recognized as an evolutionarily conserved signaling pathway employed b

278 The Hippo pathway is an evolutionarily conserved signaling pathway that plays

279 ccupancy genome wide, reduced periodicity is an evolutionarily conserved signature of nucleosome-depl

280 lation, rhythmically phosphorylates BMAL1 at an evolutionarily conserved site.

281 nism that controls the activity of retromer, an evolutionarily conserved sorting device that orchestr

282 il domain (MyoV-GTD) interacts directly with an evolutionarily conserved Spir sequence motif.

283 Draper signals through an evolutionarily conserved Src family kinase cascade to

284 ults suggest that translation reprogramming, an evolutionarily conserved starvation response, has bee

285 The centriole is an evolutionarily conserved structure built from highly

286 was taken as a representative candidate from an evolutionarily conserved subgroup that possesses high

287 droxylase domain protein 2 (PHD2) belongs to an evolutionarily conserved superfamily of 2-oxoglutarat

288 structural and functional analysis revealed an evolutionarily conserved template for nuclear hormone

289 Here we report that Spata6, an evolutionarily conserved testis-specific gene, encode

290 ASKalpha phosphorylates cytosolic G6PD6 on an evolutionarily conserved threonine residue, thereby s

291 rearrangement is controlled by refolding of an evolutionarily conserved 'tongue', which is in contac

292 rolled, in part, by MEF2, the sole member of an evolutionarily conserved transcription factor family.

293 Mediator is an evolutionarily conserved transcriptional regulatory c

294 Notch1 is an evolutionarily conserved transmembrane receptor invol

295 ational and modeling analyses indicated that an evolutionarily conserved, truncated leucine zipper mo

296 In this report, we show that an evolutionarily conserved tryptophan residue (Trp-73)

297 Despite being an evolutionarily conserved, ubiquitous, highly ordered

298 GL2-binding partner and show its key role in an evolutionarily conserved VANGL2-p62/SQSTM1-JNK pathwa

299 ition to its catalytic domain, PHD2 contains an evolutionarily conserved zinc finger domain, which we

300 Aebp2 encodes an evolutionarily conserved zinc finger protein that has