ライフサイエンスコーパス: anabolic

1 This anabolic action was mediated primarily through the stimu

2 tal boys with DMD could be due to diminished anabolic actions of androgens in muscle, and that interv

3 osteoprogenitors/osteoblasts attenuated the anabolic actions of PTH on bone formation.

4 t the importance of PAR1 mediating the known anabolic actions of thrombin in the periodontium.

5 ne released upon physical activity, displays anabolic actions on the skeleton.

6 ed in osteopenia with blunted effects of PTH anabolic actions, whereas depletion of differentiated ma

7 tributions of four PKA pathway components to anabolic activation were then examined.

8 n of a lead compound from this series showed anabolic activity by increasing levator ani muscle weigh

9 k generation times), we observe the greatest anabolic activity diversity in the slowest growing popul

10 ined as a surrogate marker for TOR-dependent anabolic activity in C. albicans.

11 otential to have therapeutic benefit through anabolic activity in muscle while sparing undesired effe

12 The gene expression analysis showed an anabolic activity of Nandrosol in Longissimus dorsi musc

13 network for longevity; the growth-promoting anabolic activity of Pol III mediates the acceleration o

14 In this study, we measured the anabolic activity of the pathogen Staphylococcus aureus

15 A direct comparison of anabolic activity using BONCAT and stable isotope labell

16 ve B cells were located within areas of high anabolic activity, including minimal association with os

17 receptor agonist with appetite-enhancing and anabolic activity.

18 mpathomimetic drugs (beta-agonists) leads to anabolic adaptations in skeletal muscle, suggesting that

19 The endocrine and bone anabolic agent parathyroid hormone increased specialized

20 ested compound 18 as the most promising bone anabolic agent, which was further evaluated for in vivo

21 ipidemic drug, has been identified as a bone anabolic agent.

22 European Union prohibited the use of anabolic agents in food producing animals since 1988.

23 Anabolic agents increased carcass (p = 0.002) and muscle

24 ional monotherapies with antiresorptives and anabolic agents into new combination regimens.

25 ata to bring this exciting class of skeletal anabolic agents to patient care.

26 echnologies--such as stem cell therapy, bone anabolic agents, genetic approaches, and nanomaterials--

27 s for muscle growth during administration of anabolic agents.

28 s, but there is a clinical need for new bone-anabolic agents.

29 es cellular energy homeostasis by inhibiting anabolic and activating catabolic processes.

30 regulates energy homeostasis by suppressing anabolic and activating catabolic processes.

31 rs might be useful to assess the response to anabolic and antiresorptive therapies, to assess complia

32 m and increased utilization of glutamine for anabolic and bioenergetic processes.

33 trient status and exercises control of vital anabolic and catabolic cellular responses such as protei

34 the localization and activities of both its anabolic and catabolic enzymes.

35 somes are metabolic organelles necessary for anabolic and catabolic lipid reactions whose numbers are

36 In analogy to anabolic and catabolic pathways in metabolism, there is

37 s are a large class of enzymes found in both anabolic and catabolic pathways that activate fatty acid

38 ry roles that SIRT1 plays in modulating both anabolic and catabolic pathways, allow us to propose the

39 r kinases in cells that is tightly linked to anabolic and catabolic pathways.

40 dipocytes confirmed the presence of distinct anabolic and catabolic phenotypes, and identified differ

41 Eukaryotic cells coordinately control anabolic and catabolic processes to maintain cell and ti

42 tolerogenicity of DCs is also determined by anabolic and catabolic processes, respectively.

43 Thr protein kinase that regulates a range of anabolic and catabolic processes.

44 s in the environment and the control of most anabolic and catabolic processes.

45 nutrient abundance and coordinate a ratio of anabolic and catabolic reactions.

46 involved in matrix synthesis or degradation (anabolic and catabolic remodeling, respectively) was qua

47 is may be initiated by age-related shifts in anabolic and catabolic responses that control bone homeo

48 elated differences in muscle mass and muscle anabolic and catabolic responses to bed rest.

49 Anabolic and catabolic signaling oppose one another in a

50 er cell growth and survival and supports the anabolic and energetic demands of these rapidly dividing

51 d proliferation, cancer cells have increased anabolic and energy demands; however, different cancer c

52 r older adults of >/=1.0 g/kg and identifies anabolic and metabolic benefits to consuming at least 20

53 acrine signaling in osteoblasts and has bone-anabolic and osteoprotective potential in adults.

54 to note that some of these genes also serve anabolic and pro-survival roles.

55 Upon metabolic stress, AMPK suppresses anabolic and promotes catabolic processes to regain ener

56 nce of mechanical loading similarly enhanced anabolic and suppressed catabolic gene expression, and p

57 can be thought of as the biosynthetic (i.e., anabolic) and degradative (i.e., catabolic) branches of

58 asis, including those involved in catabolic, anabolic, and apoptotic pathways.

59 d to encode proteins with diverse catabolic, anabolic, and ligand-binding functions and most frequent

60 etic therapy, application of scaffolds, bone anabolics, and lasers were found to be emerging technolo

61 Exposure to anabolic androgen steroids appears to cause sinusoidal c

62 ar adenoma to hepatocellular carcinoma after anabolic androgenic steroid abuse has been rarely report

63 ular carcinoma occurring in association with anabolic androgenic steroid abuse should sensitize physi

64 The oligonucleotide probes consist on anabolic androgenic steroid haptens (AAS) covalently lin

65 Continuous use of anabolic androgenic steroid in high-doses is associated

66 Prolonged high-dose anabolic-androgenic steroid (AAS) use has been associate

67 Millions of individuals have used illicit anabolic-androgenic steroids (AAS), but the long-term ca

68 glucuronide and sulfate metabolites of seven anabolic-androgenic steroids in urine.

69 potential utility of NELL-1 as a combination anabolic/antiosteoclastic therapeutic for bone loss.

70 that these processes are coupled to maintain anabolic balance in cells with mTORC1 activation, a comm

71 ant quantitation of 18 compounds (mixture of anabolics, beta-2 agonists, diuretics, stimulants, narco

72 Anabolic beta2-adrenoceptor (beta2-AR) agonists have bee

73 ogenic signalling coordinates glycolysis and anabolic biosynthesis in cancer cells remains unclear.

74 utamine-derived carbon becomes available for anabolic biosynthesis in cancer cells via the hydrolysis

75 Anabolic biosynthesis requires precursors supplied by th

76 aplerotic pathway, replenished aspartate for anabolic biosynthesis, which was critical for sustaining

77 ates key regulatory substrates and turns off anabolic biosynthetic pathways.

78 s drives aggressive disease with high p62 in anabolic cancer cells, but loss of p62 in catabolic fibr

79 uced fiber diameter, protein/DNA ratios, and anabolic capacity.

80 ory cytokine milieu, hormonal imbalance, and anabolic/catabolic imbalance, has been used to explain t

81 thetic output to accompany the ever-changing anabolic/catabolic state of the liver cell, but the wiri

82 y transcriptional reprogramming that directs anabolic changes for recovery and that augments subseque

83 implicated in accelerated growth, along with anabolic changes of an altered metabolome.

84 studies identify a translationally anchored anabolic circuit critical for cancer cell survival and a

85 eviously unidentified lineage-specific, bone anabolic compound, parbendazole, which induces osteogeni

86 and cellular catabolic processes even under anabolic conditions, indicating that GSK3 acts as a crit

87 PTH was used as the bone anabolic control.

88 with antagonism of this pathway resulting in anabolic deficits.

89 This is coupled with a high anabolic demand, necessitated by the diurnal turnover of

90 w photoreceptors balance their catabolic and anabolic demands is poorly understood.

91 glucose uptake to fuel the bioenergetic and anabolic demands of proliferating cancer cells is well r

92 t of TLR signaling that is essential for the anabolic demands of the activation and function of DCs.

93 sing different strategies to meet energy and anabolic demands to maintain growth and survival.

94 lic transformation that allows for increased anabolic demands, wherein glycolytic and tricarboxylic a

95 oid Hormone (I-PTH) is the only FDA approved anabolic drug therapy available for the treatment of ost

96 ical activity associated with CCL induces an anabolic effect in skeletal muscle undergoing regrowth a

97 We tested the hypothesis that the anabolic effect of hypocaloric, isonitrogenous nutrition

98 Therefore, although the anabolic effect of intermittent PTH treatment on trabecu

99 older adults to benefit from the synergistic anabolic effect of protein and physical activity.

100 multiple health benefits, but its potential anabolic effect on atrophied muscle has not been investi

101 es of Leu could be involved in mediating the anabolic effect(s) of Leu.

102 sthetized pigs INS infusion did not exert an anabolic effect, but rather it increased AA cycling into

103 +)-dependent deacetylase, has been linked to anabolic effects in cartilage, although the mechanisms o

104 The anabolic effects of dietary protein on skeletal muscle d

105 However, it remains unclear whether the anabolic effects of follistatin are conserved across dif

106 These results demonstrate that the anabolic effects of follistatin are influenced by the in

107 cally, in amino acid-poor conditions the pro-anabolic effects of mTORC1 are functionally opposed to g

108 Furthermore, the anabolic effects of PGC-1alpha4 in cultured murine muscl

109 nt protein-1 (MCP-1), is a mediator of PTH's anabolic effects on bone.

110 cause these side-effects and have prolonged anabolic effects on bone.

111 ing these cells has both anti-resorptive and anabolic effects on bone.

112 iates postprandial insulin secretion and has anabolic effects on the adipose tissue.

113 We report the commensal microbiota has anti-anabolic effects suppressing osteoblastogenesis and pro-

114 lls and intermittent PTHrP exposure has bone anabolic effects, suggesting that PTHrP could contribute

115 effects of IGF-1 treatment demonstrates that anabolic enhancement through IGF-1 activation of mTOR ca

116 tion of AMPK, thus revealing how AMPK senses anabolic environments in addition to cellular energy lev

117 ing drives the translation of mRNAs for many anabolic enzymes and other proteins involved in diverse

118 to reduce altered catabolism/ROS production, anabolic enzymes expression levels are also increased, r

119 nergy stress, decreasing the activity of the anabolic factors acetyl-CoA carboxylase and ribosomal pr

120 t a viable target for the development of pro-anabolic fracture treatments with a potentially broad th

121 e of lipids and amino acids as catabolic and anabolic fuels.

122 annel opening, a crucial step to mediate the anabolic function of mechanical loading in the bone.

123 As such, this work identifies an anabolic function of osteocytes as a source of Wnt in bo

124 Therefore, the anabolic function of PTEN deficiency in resting liver is

125 e regulation of AHAS, in relationship to its anabolic function.

126 Because NADPH is required not only for anabolic functions but also for counteracting different

127 -1beta and osteoarthritic synovial fluids on anabolic gene expression and increased glycosaminoglycan

128 showed significantly enhanced expression of anabolic genes ACAN and COL2A1.

129 ellular vesicles had decreased expression of anabolic genes and elevated expression of catabolic and

130 c glycolysis (the Warburg effect) to support anabolic growth and evade apoptosis.

131 reduce the stress of the operation to retain anabolic homeostasis.

132 4 fold change; O: +4 +/- 2 fold change) and anabolic hormone milieu (testosterone, Y: 367 +/- 19; O:

133 esponse to parathyroid hormone (PTH), a bone anabolic hormone, LepR(+)Runx2-GFP(low) cells increase R

134 be the result of multifactorial deficits in anabolic hormones and blunted translational efficiency a

135 nerability downstream of mTORC1 triggered by anabolic imbalance.

136 of cyclic compressive loading is a potential anabolic intervention during muscle regrowth after atrop

137 o the control of hypertrophy and efficacy of anabolic interventions.

138 trogin-1 and MuRF1; Myostatin) and increased anabolic intracellular pathways (IGF-1-mTOR-p70S6sk-1 ax

139 flammatory and resident macrophages promoted anabolic mechanisms during endochondral callus formation

140 (also known as c-MYC), a powerful driver of anabolic metabolism and growth.

141 complex 1 (mTORC1) controls cell growth and anabolic metabolism and is a critical host factor activa

142 yc has been implicated as a key regulator of anabolic metabolism and is downregulated by axotomy.

143 elated with transcripts encoding proteins of anabolic metabolism and mitochondrial function-all mTORC

144 lator of cancer cell amino acid homeostasis, anabolic metabolism and proliferation.

145 pyruvate carboxykinase 2 (PCK2) to reprogram anabolic metabolism and support cell growth.

146 de in Tfh cells by linking immune signals to anabolic metabolism and transcriptional activity.

147 ved that PMA treatment decreased cancer-type anabolic metabolism but increased ATP production, along

148 Anabolic metabolism can produce an array of small molecu

149 ivated T cells engage aerobic glycolysis and anabolic metabolism for growth, proliferation, and effec

150 s synthesize and secrete insulin to increase anabolic metabolism in an organism, and insulin synthesi

151 onstrate that PFKFB4 is essential to support anabolic metabolism in p53-deficient cancer cells and su

152 relationship between aerobic glycolysis and anabolic metabolism in the retinas of mice.

153 A cycle intermediates, as a key component of anabolic metabolism in tumor cells.

154 ctors also enhance glucose uptake to fuel an anabolic metabolism required for tissue growth and repai

155 The CBS-induced switch to an anabolic metabolism was associated with increased NCM356

156 ne-derived intermediates that are needed for anabolic metabolism were increased.

157 -mTORC1 signaling to diminish glycolysis and anabolic metabolism while increasing oxidative and catab

158 nsulin stimulation of a central modulator of anabolic metabolism, Akt/PKB; (c) inhibited insulin-stim

159 o promote a transformation from catabolic to anabolic metabolism, cell growth, and cell cycle progres

160 Oncogenic mutations drive anabolic metabolism, creating a dependency on nutrient i

161 gy sensor and tumor suppressor that inhibits anabolic metabolism, our findings reveal that direct inh

162 haperones, to promote protein biogenesis and anabolic metabolism, which are essential in development.

163 factor (M-CSF) resulted in mTORC1-dependent anabolic metabolism, which in turn promoted expression o

164 ing glucose and glutamine utilization toward anabolic metabolism.

165 urine synthesis, mediating glucose-sustained anabolic metabolism.

166 f rapamycin complex 1 (mTORC1) signaling and anabolic metabolism.

167 process across many peatland types and that anabolic microbial assimilation of CH4-C occurs.

168 cation and efficacy validation of novel bone anabolic miRs in MM opens more opportunities for novel a

169 The anabolic muscle response to a protein-rich meal during E

170 Tumors have high energetic and anabolic needs for rapid cell growth and proliferation,

171 ed cells expressing an activated form of the anabolic oncogene Ras in vitro and in vivo.

172 adjust pathway flux and accomplish specific anabolic or catabolic objectives.

173 being catabolic organelles generating ATP to anabolic organelles that generate both ATP and building

174 This ancient anabolic pathway (re-)builds carbon bonds as cleaved in

175 on of Wnt/beta-catenin signaling, a critical anabolic pathway for osteoblastic bone formation.

176 ) is a specialized plant PPO involved in the anabolic pathway of aurones.

177 ade directly regulates a major energetic and anabolic pathway that is required for neoplastic growth.

178 lso leads to the inhibition of another major anabolic pathway, the protein transport through the secr

179 metabolic switch, decreasing the activity of anabolic pathways and enhancing catabolic processes such

180 was observed, presumably owing to different anabolic pathways and membrane alteration.

181 e determines cell size or whether particular anabolic pathways are more important than others remains

182 sine triphosphatases (GTPases) and regulates anabolic pathways in response to nutrients.

183 Activated effector T (TE) cells augment anabolic pathways of metabolism, such as aerobic glycoly

184 role for PEPCK that links metabolic flux and anabolic pathways to cancer cell proliferation.

185 and sugar phosphate pathways, but the cells anabolic pathways were strikingly slow.

186 ng enhanced glucose uptake and enrichment of anabolic pathways, which can fuel tumour growth.

187 in (mTOR) signaling and upregulation of many anabolic pathways.

188 nk may be provoked by increased work through anabolic pathways.

189 bolic arms of metabolism and then drive many anabolic pathways.

190 ing catabolism of glucose and glutamine with anabolic pathways.

191 minated by upregulation of genes involved in anabolic pathways.

192 teria in responders, including enrichment of anabolic pathways.

193 rmone metabolism result in low levels of the anabolic peripheral effector hormones and contribute to

194 There follows an anabolic phase around weaning during which there is a re

195 As part of the anabolic phase of periodontal homeostasis and periodonta

196 delayed to coincide with initiation of early anabolic phase.

197 mprinted network were strikingly enriched in anabolic phenotypes, suggesting possible involvement in

198 ithin 90 d of death have a low likelihood of anabolic potential.

199 novo synthesis of multiple glutamine-derived anabolic precursors is required for cell cycle progressi

200 c oxide synthase mediated pathway, regulates anabolic process in the hypertrophy of skeletal muscle.

201 ng process of gluconeogenesis and toward the anabolic process of growth.

202 x that localizes to lysosomes to up-regulate anabolic processes and down-regulate autophagy.

203 ntial nutrient-sensing pathway that controls anabolic processes in cells.

204 y represent an alternative carbon source for anabolic processes in different tumors, therefore appear

205 integrator and master regulator of cellular anabolic processes linked to cell growth and survival.

206 Trehalose utilization fuels anabolic processes required to reliably complete cell di

207 n kinase (AMPK) has been proposed to inhibit anabolic processes such as gluconeogenesis in response t

208 and autophagy, to generate ATP, and inhibits anabolic processes that require energy, including fatty

209 cids serine and glycine are used in multiple anabolic processes that support cancer cell growth and p

210 t of rapamycin complex 1 (mTORC1) stimulates anabolic processes underlying cell growth.

211 athway in promoting catabolic and inhibiting anabolic processes, affords cells with additional time a

212 liferation through parallel induction of key anabolic processes, including protein, lipid, and nucleo

213 y available energy sources, when monomers of anabolic processes, such as amino acids, are abundant.

214 mplex 1 (mTORC1) promotes nutrient-consuming anabolic processes, such as protein synthesis.

215 tudied alpha-secretase (non-amyloidogenic or anabolic) processing and altered levels of sAPPalpha and

216 Paradoxically, this anabolic program led cells to apoptosis during chronic E

217 mycin complex 1 (mTORC1), which promotes the anabolic program that supports DZ proliferation.

218 We showed recently that ATF4 induces an anabolic program through the up-regulation of selected a

219 IRE1 attenuation is an integral component of anabolic programmes regulated by AKT-mTOR.

220 racture-associated inflammation and/or early anabolic progression during endochondral callus formatio

221 (EPA), an omega-3 fatty acid with immune and anabolic properties, may impact on clinical and nutritio

222 an blue staining, and gene expression of key anabolic proteins by real-time PCR.

223 together with the enhanced ubiquitination of anabolic proteins, help slow growth.

224 Treatment with anabolic PTH(1-34) (80 mug/kg/day) for 4 weeks failed to

225 y to generate building blocks and energy for anabolic purposes.

226 ATP production rather than utilizing it for anabolic purposes.

227 buffers fitness costs of mutations, and that anabolic rather than catabolic pathways are more stringe

228 he amino acid acceleration of a key cellular anabolic reaction may indicate a link between prebiotic

229 twork of a cell represents the catabolic and anabolic reactions that interconvert small molecules (me

230 tive when there are sufficient nutrients for anabolic reactions.

231 tallopeptidase-7, -9, and -12, diverged from anabolic remodeling linked to maximal thrombospondin and

232 lococcus, Pseudomonas, and Corynebacterium), anabolic remodeling was linked to typical members of the

233 rgent metabolic network enforces outstanding anabolic requirements for cellular proliferation.

234 muscle lipid availability may contribute to anabolic resistance in insulin-resistant conditions by i

235 Anabolic resistance is thus multifactorial.

236 This "anabolic resistance" to insulin and amino acids with lip

237 Here we investigated the aetiology of 'anabolic resistance' in older humans.

238 age and this may contribute to age-related 'anabolic resistance'.

239 d in cirrhosis and believed to contribute to anabolic resistance.

240 Complete neutralization and maximal anabolic response are achieved only by simultaneous bloc

241 e that massage in the form of CCL induces an anabolic response in muscles regrowing after an atrophy-

242 However, the mechanism(s) of this anabolic response remain(s) largely unknown.

243 e (type I), displayed a teriparatide-induced anabolic response, as well as increased hip and spine aB

244 This effect may result in an improved anabolic response, greater insulin sensitivity, and an i

245 roid axis in patients with NTIS, inducing an anabolic response.

246 a weight "threshold" paradigm: in the obese, anabolic responses are triggered by adiposity-related si

247 uman clinical trials demonstrates short-term anabolic responses in excess of those seen with teripara

248 ed-state circulatory responses would improve anabolic responses to nutrition, fed-state increases in

249 ion of MBF does not, however, enhance muscle anabolic responses to nutrition.

250 These data confirm the anabolic role of OA in postnatal bone formation.

251 odies the merger of a very potent and proven anabolic selective agonist of the prostaglandin EP4 rece

252 singly, PI3K-Akt signaling, which is a major anabolic signaling and normally inhibits GSK3 activity,

253 mammals, suggesting the existence of common anabolic signaling networks that coordinate the developm

254 This review focuses on anabolic signaling pathways through which insulin, amino

255 ting that GSK3 acts as a critical sensor for anabolic signaling to regulate AMPK.

256 otein and 3 g fat) to assess skeletal muscle anabolic signaling, amino acid transporters [large neutr

257 on kinetics, plasma amino acid availability, anabolic signaling, and subsequent myofibrillar protein

258 etics, postprandial amino acid availability, anabolic signaling, and the subsequent myofibrillar prot

259 ad-induced muscle hypertrophy and associated anabolic signaling.

260 nsulin was measured via ELISA and indices of anabolic signalling (e.g. Akt/mTORC1) by immunoblotting

261 While HMB and Leu both increased anabolic signalling (mechanistic target of rapamycin; mT

262 lly, individual pathways through which the 3 anabolic signals act to modulate mTORC1 signaling will b

263 egulate their expression) to promote protein-anabolic signals for retention or recovery of lean tissu

264 in a global imbalance between catabolic and anabolic signals, leading to tissue wasting and, ultimat

265 amycin (mTOR), a kinase that is activated by anabolic signals, plays fundamental roles in regulating

266 g fat mass, potentially dependent on altered anabolic signals, that reduces muscle sensitivity to foo

267 h teriparatide, the only currently available anabolic skeletal agent.

268 and ultimately shifting homeostasis to a pro-anabolic state in disc cells.

269 eletal muscle of transgenic mice fostered an anabolic state of energy and protein balance.

270 fferent compound treatments and verified the anabolic state of the cells with regard to the oxidative

271 e rapid identification and quantification of anabolic steroid esters has been evaluated.

272 ddition of anions, in ammonium salt form, to anabolic steroid samples as ionization enhancers and hav

273 Nandrolone, an anabolic steroid, has been shown to inhibit Notch signal

274 Nonpolar anabolic steroids are doping agents that typically do no

275 Anabolic steroids marketed as bodybuilding supplements t

276 Anabolic steroids may still play a role in combination w

277 supplements, growth hormone derivatives, or anabolic steroids to achieve their desired physique; 2.5

278 The major implicated agents include anabolic steroids, green tea extract, and multi-ingredie

279 tization has been incorporated for analyzing anabolic steroids.

280 role of miRNA in the adaptation of muscle to anabolic stimulation and reveals a significant impairmen

281 monstrates that gut microbiota provide a net anabolic stimulus to the skeleton, which is likely media

282 TOR occurs in human muscle in response to an anabolic stimulus, events that appear to be primarily in

283 ficacy of RNA interference (RNAi)-based bone anabolic strategies still exist because of the lack of d

284 ized LNPs could act as a new RNAi-based bone anabolic strategy, advancing the targeted delivery selec

285 of cytoplasmic contents for regeneration of anabolic substrates during nutritional or inflammatory s

286 potential for oxidative phosphorylation and anabolic substrates for cell growth, repair and prolifer

287 evels of glycolytic intermediates for use as anabolic substrates.

288 marcb1 activates the Myc network, driving an anabolic switch that increases protein metabolism and ad

289 ort that this weaning-associated miRNA is an anabolic target.

290 ew treatment options are available, and bone anabolic therapies have not been tested in clinical tria

291 n locally and provide a novel avenue to bone anabolic therapy by antagonizing LRP4 sclerostin facilit

292 lator of osteoblast function and is the only anabolic therapy currently approved for treatment of ost

293 intermittent parathyroid hormone (PTH) bone anabolic therapy involves SOST expression reduction by i

294 mal stem cells has been proposed as skeletal anabolic therapy to enhance bone formation, but the mech

295 idespread reorganization of the cell from an anabolic to a catabolic state.

296 Anabolic TORC1-dependent processes require significant a

297 cal assays allowed for the identification of anabolic, transport, catabolic and regulatory portions o

298 arathyroid hormone (PTH) is the only current anabolic treatment for osteoporosis in the United States

299 largely unaltered, OSM could represent a new anabolic treatment for unconsolidated bone fractures.

300 pyruvate fate is an important determinant of anabolic versus catabolic metabolism.