ライフサイエンスコーパス: analgesic drug

1 phenol (APAP, or paracetamol), a hepatotoxic analgesic drug.

2 its, and therefore might not be an effective analgesic drug.

3 nd possibly a promising candidate as a novel analgesic drug.

4 d possibly a promising candidate for a novel analgesic drug.

5 the most commonly used anti-inflammatory and analgesic drug.

6 suggests a new avenue for the development of analgesic drugs.

7 foundation for investigating new classes of analgesic drugs.

8 rders and provide an approach for developing analgesic drugs.

9 5/p35 may be a target for the development of analgesic drugs.

10 ntipyretic and one of the most commonly used analgesic drugs.

11 d therefore increase the clinical utility of analgesic drugs.

12 ful in the assessment of peripherally acting analgesic drugs.

13 onal signal transduction mechanisms for some analgesic drugs.

14 ression of pain, and in the action of opiate analgesic drugs.

15 btype-selective muscarinic agonists as novel analgesic drugs.

16 gets of native opioid peptides and addictive analgesic drugs.

17 pairment, and pain relief obtained by taking analgesic drugs.

18 e to the acute and chronic actions of opioid analgesic drugs.

19 sts, as well as P2X antagonists as potential analgesic drugs.

20 id (aspirin), and paracetamol-caffeine-based analgesic drugs.

21 minimizing the predilection for sedative and analgesic drug accumulation with prolongation of effect

22 d to a wealth of molecular targets for novel analgesic drugs and many clinical drug trials.

23 New developments in analgesic drugs and techniques are being applied to the

24 ugh to require increased use of sedative and analgesic drugs, and is among the events that predict cl

25 gate, provides little support for the use of analgesic drugs as chemoprevention for this disease.

26 ASC alone (treatment could include steroids, analgesic drugs, bronchodilators, palliative radiotherap

27 , and non-steroidal anti-inflammatory drugs) analgesic drugs can markedly enhance pain relief in the

28 Acetaminophen (AAP), a widely used analgesic drug, can damage various organs when taken in

29 t that is also a short acting anesthetic and analgesic drug, can produce analgesia and decrease morph

30 Overdose of acetaminophen, a widely used analgesic drug, can result in severe hepatotoxicity and

31 Salicylamide (SAL), an analgesic drug, caused a potent and long-lasting inhibit

32 and modulation reveals potential targets for analgesic drug development and new therapeutic opportuni

33 d wiring patterns that provide clues for new analgesic drug development strategies.

34 ss, the chances of success could increase if analgesic drug development strategy changed.

35 r channel function, potentially facilitating analgesic drug development studies.

36 d receptor (DOR) is an attractive target for analgesic drug development.

37 patients but may also reveal new targets for analgesic drug development.

38 may have the potential of emerging as novel analgesic drugs devoid of tolerance, dependence, and rel

39 r testing not only antiinflammatory but also analgesic drugs for potential use in RA, and highlights

40 st significance in the development of potent analgesic drugs for the treatment of severe pain.

41 a-1, the receptor for the anti-epileptic and analgesic drug gabapentin.

42 itization are known, inadequacies of current analgesic drugs have prompted a search for additional ta

43 Delivery of promising analgesic drugs is often impeded by the perineurium, whi

44 eported that the short-acting anesthetic and analgesic drug midazolam can produce analgesia and decre

45 o, 2.9; p < 0.001), lower amount of sedative-analgesic drugs (odds ratio, 1.9; p = 0.03), higher vaso

46 Bone pain, use of analgesic drugs, performance status, and quality of life

47 Commonly used opioid and nonopioid analgesic drugs produce adverse effects and are of limit

48 t reviews have suggested that newly designed analgesic drugs should incorporate multiple targets.

49 th bone metastases, in part because existing analgesic drugs show only limited efficacy in many patie

50 Repeated use of opiate analgesic drugs such as morphine for the relief of chron

51 lesser degree than opioid peptides and other analgesic drugs, such as methadone, and previous studies

52 rget for the development of a novel class of analgesic drugs, suggesting that activation of TREK-1 co

53 e all been shown to be potentially selective analgesic drug targets in some animal pain models.

54 egabalin with conventional antiepileptic and analgesic drug targets is likely to be modest, at best,

55 into human pain mechanisms and suggested new analgesic drug targets.

56 egulation mediating type-specific effects of analgesic drugs that activate more than one type of opio

57 required, 1 which includes a combination of analgesic drug therapy, radiation therapy, hormonal ther

58 deciliter [3.0 mmol per liter]), bone pain, analgesic-drug use, performance status, and quality of l

59 nses of geriatric patients to anesthetic and analgesic drugs used during ambulatory surgery.

60 Here, we develop a strategy to discover analgesic drugs via structure-based virtual screening ba

61 NCE STATEMENT Acetaminophen is a widely used analgesic drug with multiple but only incompletely under

62 being replaced by a combination of nonopioid analgesic drugs with diverse modes of action as part of

63 uld provide an approach toward the design of analgesic drugs with reduced side effects.