ライフサイエンスコーパス: anaphase-promoting complex

1 luding an A-type cyclin and a subunit of the anaphase promoting complex.

2 conveys lack of tension or attachment to the anaphase promoting complex.

3 l: the destruction box sequence bound to the anaphase-promoting complex.

4 transmitting a "wait anaphase" signal to the anaphase-promoting complex.

5 proteins that function as activators of the anaphase-promoting complex.

6 previous observations that Tax activates the anaphase-promoting complex.

7 ll cycle-associated E3-ubiquitin ligase, the anaphase-promoting complex.

8 tion and upregulation of E3 ubiquitin ligase anaphase-promoting complex 10 activity, which targeted E

9 ago, the first post-mitotic function of the anaphase-promoting complex, a major cell cycle-regulated

10 nd thereby promoting SPOP degradation by the anaphase-promoting complex activator FZR1.

11 reakdown, and provides an effective block to anaphase-promoting complex activity, and consequently th

12 erview of the function and regulation of the anaphase-promoting complex, an E3 ubiquitin ligase that

13 tion cascade that leads to inhibition of the anaphase promoting complex and cell cycle arrest.

14 se I and II, was dependent on myosin II, the anaphase promoting complex and separase, but did not req

15 ibitor 1 (emi1), a negative regulator of the Anaphase Promoting Complex, and use the mutant to examin

16 The anaphase promoting complex (APC) controls the degradatio

17 int signaling, the role kinetochores play in anaphase promoting complex (APC) inhibition remains uncl

18 The anaphase promoting complex (APC) is a ubiquitin ligase t

19 The anaphase promoting complex (APC) targets proteins for de

20 repressed genes is Emi1, an inhibitor of the anaphase promoting complex (APC) which is degraded durin

21 Anaphase promoting complex (APC)-Cdh1 targets multiple m

22 ming of HURP action and its turnover via the anaphase promoting complex (APC)-proteasome system, ther

23 y the microarray should be substrates of the anaphase promoting complex (APC).

24 encodes a meiosis-specific activator of the anaphase promoting complex (APC).

25 ndent protein kinase (Cdk) families, and the Anaphase Promoting Complex (APC).

26 Thereafter, the anaphase promoting complex (APC/C) is activated and chro

27 complex (MCC), which binds and inhibits the anaphase promoting complex (APC/C).

28 in B2 from destruction by the Cdh1-activated anaphase-promoting complex (APC(Cdh1)) and remains impor

29 Anaphase-promoting complex (APC) activation results in d

30 euploidy by coupling anaphase onset, through anaphase-promoting complex (APC) activation, with chromo

31 FZR1 is an anaphase-promoting complex (APC) activator best known fo

32 arrests cells at metaphase by inhibiting the anaphase-promoting complex (APC) and its coactivator Cdc

33 o the identification of many subunits of the anaphase-promoting complex (APC) associated with PHF8.

34 nce of ubiquitylation events mediated by the anaphase-promoting complex (APC) based on short redundan

35 ling and suppresses phosphorylation of CDC27-anaphase-promoting complex (APC) during mitosis, thereby

36 In vitro, the anaphase-promoting complex (APC) E3 ligase functions wit

37 pindle assembly checkpoint, which results in anaphase-promoting complex (APC) inhibition.

38 en reported that dampened translation of the anaphase-promoting complex (APC) inhibitor Emi2 at MI al

39 entified the mitotic cyclin A (CYCA) and the anaphase-promoting complex (APC) inhibitor RCA1/Emi1 as

40 The anaphase-promoting complex (APC) is a ubiquitin ligase t

41 The Anaphase-Promoting Complex (APC) is an E3 ubiquitin liga

42 A pulse-driven CDK1-anaphase-promoting complex (APC) model corroborated thes

43 The ubiquitin ligase anaphase-promoting complex (APC) recruits the coactivato

44 The anaphase-promoting complex (APC) regulates cell division

45 The anaphase-promoting complex (APC) regulates the eukaryoti

46 the large, multisubunit E3 ubiquitin ligase anaphase-promoting complex (APC) that targets effector p

47 The Skp1-Cul1-F-box (SCF) and anaphase-promoting complex (APC) ubiquitin ligases targe

48 We show that the activity of the anaphase-promoting complex (APC), an E3 that regulates t

49 directly inhibiting its interaction with the anaphase-promoting complex (APC), an E3 ubiquitin ligase

50 forces a cell-cycle arrest by inhibiting the anaphase-promoting complex (APC), an E3 ubiquitin ligase

51 ctivity of the master regulator known as the anaphase-promoting complex (APC), brought about through

52 ed by another critical ubiquitin ligase, the anaphase-promoting complex (APC), in association with it

53 Cdh1, a coactivator of the anaphase-promoting complex (APC), is a potential tumor s

54 se is initiated when a ubiquitin ligase, the anaphase-promoting complex (APC), triggers the destructi

55 at Eco2, like sororin, is a substrate of the anaphase-promoting complex (APC), which ensures that pro

56 ing the metaphase-anaphase transition by the anaphase-promoting complex (APC), which recognizes the d

57 nt is the Cdc20 protein, which initiates the anaphase-promoting complex (APC)-dependent degradation o

58 -1-dependent early translocation followed by anaphase-promoting complex (APC)-dependent spindle rotat

59 ation pathways in yeast, including Rsp5- and anaphase-promoting complex (APC)-mediated pathways.

60 ies of cyclin-dependent kinase (Cdk) and the anaphase-promoting complex (APC).

61 neuploidy by restraining the activity of the anaphase-promoting complex (APC).

62 and Cdh1, the two mitotic activators of the anaphase-promoting complex (APC).

63 etochores into the cytoplasm, inhibiting the anaphase-promoting complex (APC).

64 partly attributed to the inactivation of the anaphase-promoting complex (APC).

65 vator of an E3 ubiquitin ligase known as the anaphase-promoting complex (APC).

66 sis depends on protein ubiquitination by the anaphase-promoting complex (APC).

67 s triggered by a ubiquitin ligase called the anaphase-promoting complex (APC).

68 The ubiquitin ligase activity of the anaphase-promoting complex (APC)/cyclosome needs to be t

69 show that MOAP-1 is a novel substrate of the anaphase-promoting complex (APC/C(Cdh1)) ubiquitin ligas

70 process is associated with its regulation of anaphase-promoting complex (APC/C) activity.

71 sely when substrates of the ubiquitin ligase anaphase-promoting complex (APC/C) are degraded.

72 regulatory proteins by the large multimeric anaphase-promoting complex (APC/C) controls sister chrom

73 ning E3 ubiquitin ligase able to inhibit the anaphase-promoting complex (APC/C) directly.

74 Here, we report that the anaphase-promoting complex (APC/C) efficiently synthesiz

75 The anaphase-promoting complex (APC/C) is a multimeric RING

76 The ubiquitin ligase anaphase-promoting complex (APC/C) is essential for cell

77 Ubiquitination by the anaphase-promoting complex (APC/C) is essential for prol

78 The anaphase-promoting complex (APC/C) orchestrates progress

79 sequence motifs in several substrates of the anaphase-promoting complex (APC/C) that are required for

80 cycle protein 27 (Cdc27), a component of the anaphase-promoting complex (APC/C), as a novel interacti

81 o the mitotic spindle with activation of the anaphase-promoting complex (APC/C), the E3 ubiquitin lig

82 wed that LANA interacted physically with the anaphase-promoting complex (APC/C), thus promoting the d

83 progression requires the E3 ubiquitin ligase anaphase-promoting complex (APC/C), which uses the subst

84 inhibit Cdc20, the activating subunit of the anaphase-promoting complex (APC/C).

85 int complex (MCC), a potent inhibitor of the anaphase-promoting complex (APC/C).

86 lated ubiquitylation events catalyzed by the anaphase-promoting complex (APC/C).

87 tivation of the E2 Ube2S by its RING-E3, the anaphase-promoting complex (APC/C); while phosphorylatio

88 In eukaryotes, the anaphase-promoting complex (APC/C, also known as the cyc

89 vious studies implied that activation of the anaphase-promoting complex (APC/cyclosome) is involved i

90 We have identified the Cdh1-anaphase promoting complex as a putative E3 ligase that

91 This study implicates the anaphase-promoting complex as a mediator of MIWI ubiquit

92 eating a toggle switch for activation of the anaphase-promoting complex as embryonic cells exit mitos

93 tin ligase Cdc20-APC (cell division cycle 20-anaphase promoting complex) as a centrosomal substrate o

94 ese subprocesses are largely governed by the anaphase-promoting complex, Aurora B kinase, and kinesin

95 only in the recruitment of substrates to the anaphase-promoting complex but also in its activation.

96 me decreased, resulting in an attenuation of anaphase-promoting complex/C ubiquitin ligase activity a

97 bundance is restricted to S phase in part by anaphase promoting complex Cdc20-homologue 1 (APC(Cdh1))

98 Anaphase-promoting complex Cdc20 (APC(Cdc20)) plays pivo

99 the major mitotic E3 ubiquitin ligase Cdc20-anaphase promoting complex (Cdc20-APC) regulates presyna

100 Among E3 ubiquitin ligases, Cdh1-anaphase promoting complex (Cdh1-APC) and Cdc20-APC have

101 The ubiquitin ligase Cdh1-anaphase promoting complex (Cdh1-APC) plays a key role i

102 The E3 ubiquitin ligase Cdh1-anaphase-promoting complex (Cdh1-APC) and its substrate

103 ulatory subunit of the ubiquitin ligase Cdh1-anaphase-promoting complex (Cdh1-APC), profoundly impair

104 Here we show that Parkin interacts with anaphase promoting complex/cyclosome (APC/C) coactivator

105 is mediated by increased destruction by the anaphase promoting complex/cyclosome (APC/C) during meio

106 at changes at kinetochores are essential for anaphase promoting complex/cyclosome (APC/C) inhibition.

107 The anaphase promoting complex/cyclosome (APC/C) is a large

108 The anaphase promoting complex/cyclosome (APC/C) mediates th

109 CDKs and the anaphase promoting complex/cyclosome (APC/C) restrict li

110 The SAC prevents the anaphase promoting complex/cyclosome (APC/C) ubiquitin l

111 Assembly Checkpoint (SAC) that inhibits the Anaphase Promoting Complex/Cyclosome (APC/C) ubiquitin l

112 matid pairs become bioriented, the E3 ligase anaphase promoting complex/cyclosome (APC/C) ubiquitylat

113 , were found to physically interact with the anaphase promoting complex/cyclosome (APC/C)(Cdc20) and

114 cycle onset is controlled by activity of the Anaphase Promoting Complex/Cyclosome (APC/C), a multisub

115 are post-transcriptionally controlled by the Anaphase Promoting Complex/Cyclosome (APC/C), a specific

116 a female, meiosis-specific activator of the Anaphase Promoting Complex/Cyclosome (APC/C), an E3 ubiq

117 xpression of the Cdc27 (APC3) subunit of the anaphase promoting complex/cyclosome (APC/C), which resu

118 MCC inhibits the ubiquitin ligase anaphase promoting complex/cyclosome (APC/C), whose acti

119 is an evolutionarily conserved regulator of anaphase promoting complex/cyclosome (APC/C).

120 MCC), which inhibits Cdc20 to inactivate the Anaphase Promoting Complex/Cyclosome (APC/C).

121 well-established substrate receptors for the Anaphase Promoting Complex/Cyclosome (APC/C).

122 factor (MPF) by inhibiting ubiquitin ligase anaphase promoting complex/cyclosome (APC/C).

123 T), a meiosis-specific form of the E3 ligase anaphase promoting complex/cyclosome (APC/C).

124 MAK is overexpressed, the binding of CDH1 to anaphase promoting complex/cyclosome decreased, resultin

125 tly in metaphase I if the Cortex form of the Anaphase Promoting Complex/Cyclosome is inactive.

126 of-function allele in an APC5 subunit of the anaphase promoting complex/cyclosome.

127 on and activation of the mitotic form of the anaphase-promoting complex/cyclosome (APC(Cdc20)).

128 Here, we show that inactivation of the anaphase-promoting complex/cyclosome (APC(Cdh1)) has the

129 Some RING E3s, including anaphase-promoting complex/cyclosome (APC), catalyze pol

130 uch E3 is the gigantic, multisubunit 1.2-MDa anaphase-promoting complex/cyclosome (APC), which contro

131 oint delays anaphase onset by inhibiting the anaphase-promoting complex/cyclosome (APC/C(Cdc20)) [2].

132 Activation of anaphase-promoting complex/cyclosome (APC/C(Cdc20)) by C

133 ubiquitination activities of CDC20-activated anaphase-promoting complex/cyclosome (APC/C(CDC20)).

134 pression is lost after differentiation, high anaphase-promoting complex/cyclosome (APC/C) activity de

135 Cdk1 play compensatory roles to suppress the anaphase-promoting complex/cyclosome (APC/C) activity ea

136 ntriole disengagement depend on separase and anaphase-promoting complex/cyclosome (APC/C) activity, w

137 injection of a competitive inhibitor of the anaphase-promoting complex/cyclosome (APC/C) after knock

138 checkpoint complex (MCC), which inhibits the anaphase-promoting complex/cyclosome (APC/C) and blocks

139 20, resulting in prolonged inhibition of the anaphase-promoting complex/cyclosome (APC/C) and delayed

140 o-EM and biochemistry show that the human E3 anaphase-promoting complex/cyclosome (APC/C) and its two

141 ukaryote with a semiopen mitosis, lacking an anaphase-promoting complex/cyclosome (APC/C) and many of

142 CLIN A and CYCLIN B are ubiquitylated by the anaphase-promoting complex/cyclosome (APC/C) and then su

143 till occur for a considerable time after the anaphase-promoting complex/cyclosome (APC/C) becomes act

144 duration is determined by activation of the anaphase-promoting complex/cyclosome (APC/C) bound to it

145 Activation of the anaphase-promoting complex/cyclosome (APC/C) by Cdc20 is

146 The switch from activation of the anaphase-promoting complex/cyclosome (APC/C) by CDC20 to

147 Here we show that Arabidopsis anaphase-promoting complex/cyclosome (APC/C) coactivator

148 The anaphase-promoting complex/cyclosome (APC/C) controls a

149 The ubiquitin ligase called the anaphase-promoting complex/cyclosome (APC/C) controls mi

150 ion of cell cycle regulatory proteins by the anaphase-promoting complex/cyclosome (APC/C) controls si

151 The anaphase-promoting complex/cyclosome (APC/C) controls th

152 In this study we report a novel role for the anaphase-promoting complex/cyclosome (APC/C) during this

153 The anaphase-promoting complex/cyclosome (APC/C) E3 ubiquiti

154 HL associates with Cdh1, an activator of the anaphase-promoting complex/cyclosome (APC/C) E3 ubiquiti

155 tes recognition of mitotic substrates by the anaphase-promoting complex/cyclosome (APC/C) E3 ubiquiti

156 in late mitosis and early G(1) phase by the anaphase-promoting complex/cyclosome (APC/C) E3 ubiquiti

157 several means, including inactivation of the anaphase-promoting complex/cyclosome (APC/C) E3 ubiquiti

158 y-destroyed cyclins-Cyclins A and B-restrain anaphase-promoting complex/cyclosome (APC/C) function, w

159 Here, we demonstrate that the anaphase-promoting complex/cyclosome (APC/C) in complex

160 -D159, causes failure of inactivation of the anaphase-promoting complex/cyclosome (APC/C) in interpha

161 triction is required for accumulation of the anaphase-promoting complex/cyclosome (APC/C) inhibitor E

162 Expression of the anaphase-promoting complex/cyclosome (APC/C) inhibitor E

163 rrested at Metaphase II by Emi2, the meiotic anaphase-promoting complex/cyclosome (APC/C) inhibitor.

164 The anaphase-promoting complex/cyclosome (APC/C) is a cell c

165 The anaphase-promoting complex/cyclosome (APC/C) is a large

166 The anaphase-promoting complex/cyclosome (APC/C) is a large

167 The anaphase-promoting complex/cyclosome (APC/C) is a large

168 The anaphase-promoting complex/cyclosome (APC/C) is a massiv

169 The anaphase-promoting complex/cyclosome (APC/C) is a member

170 The anaphase-promoting complex/cyclosome (APC/C) is a protei

171 The Anaphase-Promoting Complex/Cyclosome (APC/C) is an E3 ub

172 The Anaphase-Promoting Complex/Cyclosome (APC/C) is an essen

173 The anaphase-promoting complex/cyclosome (APC/C) is an essen

174 The anaphase-promoting complex/cyclosome (APC/C) is an ubiqu

175 The anaphase-promoting complex/cyclosome (APC/C) is the ubiq

176 Proteasomal degradation of cyclin B by anaphase-promoting complex/cyclosome (APC/C) is, in part

177 The anaphase-promoting complex/cyclosome (APC/C) promotes an

178 For example, the anaphase-promoting complex/cyclosome (APC/C) promotes th

179 The anaphase-promoting complex/cyclosome (APC/C) regulates s

180 ith abundance profiles most similar to known Anaphase-Promoting Complex/Cyclosome (APC/C) substrates

181 e we show that another ubiquitin ligase, the anaphase-promoting complex/cyclosome (APC/C) targets Ams

182 get of the SAC is Cdc20, which activates the anaphase-promoting complex/cyclosome (APC/C) that trigge

183 i1/NuMA/Dynein-dynactin) network anchors the anaphase-promoting complex/cyclosome (APC/C) to the mito

184 The anaphase-promoting complex/cyclosome (APC/C) ubiquitin l

185 two-step destruction process mediated by the anaphase-promoting complex/cyclosome (APC/C) ubiquitin l

186 The checkpoint system acts on the Anaphase-Promoting Complex/Cyclosome (APC/C) ubiquitin l

187 that pRB is physically linked to the active anaphase-promoting complex/cyclosome (APC/C) ubiquitin l

188 ostnatal deletion of Cdh1, a cofactor of the anaphase-promoting complex/cyclosome (APC/C) ubiquitin l

189 The anaphase-promoting complex/cyclosome (APC/C) ubiquitin l

190 0, and MAD2, directly binds and inhibits the anaphase-promoting complex/cyclosome (APC/C) until all c

191 The MCC inhibits the anaphase-promoting complex/cyclosome (APC/C) until the c

192 bub3Delta cells had impaired binding of the anaphase-promoting complex/cyclosome (APC/C) with its ac

193 An example is the anaphase-promoting complex/cyclosome (APC/C), a 13-subun

194 -B-Insensitive 4) are negative regulators of anaphase-promoting complex/cyclosome (APC/C), a multisub

195 of proteins are essential activators of the anaphase-promoting complex/cyclosome (APC/C), a multisub

196 MCC inhibits the anaphase-promoting complex/cyclosome (APC/C), a ubiquiti

197 Cdc20, a cofactor of the E3 ubiquitin ligase anaphase-promoting complex/cyclosome (APC/C), accumulate

198 netochores by inhibiting the activity of the Anaphase-Promoting Complex/Cyclosome (APC/C), an E3 ubiq

199 The anaphase-promoting complex/cyclosome (APC/C), an E3 ubiq

200 The anaphase-promoting complex/cyclosome (APC/C), an essenti

201 ense unattached kinetochores, to inhibit the anaphase-promoting complex/cyclosome (APC/C), and to del

202 The two co-activators of the anaphase-promoting complex/cyclosome (APC/C), Cdc20 and

203 A multi-subunit ubiquitin ligase, the anaphase-promoting complex/cyclosome (APC/C), regulates

204 chromosomes and which binds and inhibits the anaphase-promoting complex/cyclosome (APC/C), the E3 ubi

205 two destruction boxes and is mediated by the anaphase-promoting complex/cyclosome (APC/C), whereas de

206 es with the function of the ubiquitin ligase anaphase-promoting complex/cyclosome (APC/C), which, tog

207 n the proteasome after ubiquitylation by the anaphase-promoting complex/cyclosome (APC/C)-cadherin 1

208 t for the activation of the ubiquitin ligase Anaphase-Promoting Complex/Cyclosome (APC/C)-Cdc20 that

209 Together, our results indicate that anaphase-promoting complex/cyclosome (APC/C)-Cdh1 specif

210 We further show that GPC1 inhibits the anaphase-promoting complex/cyclosome (APC/C)-mediated de

211 nt cells in contrast to somatic cells, where anaphase-promoting complex/cyclosome (APC/C)-mediated pr

212 in Saccharomyces cerevisiae is regulated by anaphase-promoting complex/cyclosome (APC/C)-mediated pr

213 g proper bipolar chromosomal attachment with anaphase-promoting complex/cyclosome (APC/C)-mediated se

214 ction during M-phase exit is mediated by the anaphase-promoting complex/cyclosome (APC/C)-targeted ub

215 ubules promote chromosome association of the anaphase-promoting complex/cyclosome (APC/C).

216 complex (MCC) inhibits the ubiquitin ligase anaphase-promoting complex/cyclosome (APC/C).

217 ase by targeting Cdc20, the activator of the anaphase-promoting complex/cyclosome (APC/C).

218 x (MCC), which inhibits the ubiquitin ligase anaphase-promoting complex/cyclosome (APC/C).

219 between Ubp15 and Cdh1, an activator of the anaphase-promoting complex/cyclosome (APC/C).

220 al domain required for ubiquitination by the Anaphase-Promoting Complex/Cyclosome (APC/C).

221 proteins inhibit Cdc20, an activator of the anaphase-promoting complex/cyclosome (APC/C).

222 mammalian Cdh1, a regulatory subunit of the anaphase-promoting complex/cyclosome (APC/C).

223 mitosis, and its degradation depends on the anaphase-promoting complex/cyclosome (APC/C).

224 quires Fzr/Cdh1, a positive regulator of the Anaphase-Promoting Complex/Cyclosome (APC/C).

225 ork that inhibits premitotic activity of the anaphase-promoting complex/cyclosome (APC/C).

226 checkpoint complex (MCC), which inhibits the anaphase-promoting complex/cyclosome (APC/C).

227 assembles and inhibits the ubiquitin ligase Anaphase-Promoting Complex/Cyclosome (APC/C).

228 MCC formation inhibits the anaphase-promoting complex/cyclosome (Cdc20-APC/C), ther

229 m mitosis to endoreduplication by modulating anaphase-promoting complex/cyclosome activity, which are

230 ation of Drp1, catalyzed by the APC/C(Cdh1) (anaphase-promoting complex/cyclosome and its coactivator

231 a diffusible inhibitor of APC/C(Cdc20) (the anaphase-promoting complex/cyclosome and its coactivator

232 At the first meiotic division, anaphase-promoting complex/cyclosome associated with Cdc

233 e Mad2 is converted into an inhibitor of the anaphase-promoting complex/cyclosome bound to its specif

234 This is achieved through inhibition of the anaphase-promoting complex/cyclosome by a kinetochore-de

235 CARP-1 also binds with anaphase-promoting complex/cyclosome co-activators Cdc20

236 proliferation, including most targets of the anaphase-promoting complex/cyclosome complex, a set of g

237 ligases, the Skp/cullin/F-box-containing and anaphase-promoting complex/cyclosome complexes.

238 brid screen revealed CARP-1 binding with the anaphase-promoting complex/cyclosome E3 ubiquitin ligase

239 BubR1M that contribute to Cdc20 binding and anaphase-promoting complex/cyclosome inhibition: a destr

240 Cdc20 is an activator of the anaphase-promoting complex/cyclosome that initiates anap

241 a meiosis-specific targeting subunit of the anaphase-promoting complex/cyclosome that regulates mult

242 stl is required for the timely activation of anaphase-promoting complex/cyclosome to allow meiosis I

243 he G1 phase of the cell cycle is achieved by anaphase-promoting complex/cyclosome(Cdh1) (APC/C(Cdh1))

244 iated by the 1.2-MDa ubiquitin ligase APC/C (anaphase-promoting complex/cyclosome) and its coactivato

245 Here we demonstrate that APC/C (anaphase-promoting complex/cyclosome) enzyme is active i

246 -3 is internalized and degraded in an APC/C (anaphase-promoting complex/cyclosome)-dependent manner.

247 CC is a critical checkpoint inhibitor of the anaphase-promoting complex/cyclosome, a ubiquitin ligase

248 The relevant ubiquitin ligase, the anaphase-promoting complex/cyclosome, also targets cycli

249 thway involving the mitotic kinase PLK1, the anaphase-promoting complex/cyclosome, and the proteasome

250 tor of DNA pre-RC, and Emi1, an inhibitor of anaphase-promoting complex/cyclosome, are elevated in Pl

251 y preventing degradation of cyclin B1 by the anaphase-promoting complex/cyclosome, but some cells eva

252 te and characterize recombinant forms of the anaphase-promoting complex/cyclosome, cohesin, and kinet

253 Likewise, Cdc20, an activator of the anaphase-promoting complex/cyclosome, is excluded from i

254 bility of RNF157 during the cell cycle in an anaphase-promoting complex/cyclosome-CDH1-dependent mann

255 le ensuring timely activation of separase by anaphase-promoting complex/cyclosome-dependent degradati

256 x, and its association and inhibition of the anaphase-promoting complex/cyclosome.

257 of the checkpoint is the E3 ubiquitin ligase anaphase-promoting complex/cyclosome.

258 actions, causing premature activation of the anaphase-promoting complex/cyclosome.

259 chromatid segregation is independent of the anaphase-promoting complex/cyclosome.

260 e-independent failure of inactivation of the anaphase-promoting complex/cyclosome.

261 stributed throughout the cell to inhibit the anaphase-promoting complex/cyclosome.

262 s important for checkpoint inhibition of the anaphase-promoting complex/cyclosome.

263 ugating enzyme that donates ubiquitin to the anaphase-promoting complex/cyclosome.

264 rylation of cdk1 inhibited activation of the anaphase promoting complex degradation system, which was

265 ion mutant compromised for the kinesin-8 and anaphase-promoting complex-driven spindle-disassembly pa

266 ell cycle kinase Mps1, a known target of the anaphase-promoting complex E3, require Ufd2 enzyme.

267 WEE1 interacts with the anaphase promoting complex, functioning as a negative re

268 e groups that control the M phase, including anaphase-promoting complex genes, via aberrant transcrip

269 ve identified additional novel roles for the anaphase-promoting complex in diverse aspects of neurona

270 perspective on future investigations of the anaphase-promoting complex in neurobiology.

271 discuss the functions and mechanisms of the anaphase-promoting complex in neurogenesis, glial differ

272 The anaphase-promoting complex in partnership with its activ

273 and Nr4a receptors induce components of the anaphase-promoting complex, including ubiquitin-conjugat

274 independent of a conserved component of the anaphase-promoting complex, indicating a unique role for

275 The anaphase-promoting complex is required for similar steps

276 ION CYCLE16 (CDC16), a core component of the Anaphase Promoting Complex, is one of the key mediators

277 lti-subunit E3 ubiquitin ligase known as the anaphase-promoting complex or cyclosome (APC/C [2]).

278 itionally, we found that Pim-1 regulates the anaphase-promoting complex or cyclosome (APC/C complex)

279 The anaphase-promoting complex or cyclosome (APC/C) is a con

280 The anaphase-promoting complex or cyclosome (APC/C) is a lar

281 The anaphase-promoting complex or cyclosome (APC/C) is a ubi

282 The anaphase-promoting complex or cyclosome (APC/C) is a ubi

283 The anaphase-promoting complex or cyclosome (APC/C) is an un

284 The anaphase-promoting complex or cyclosome (APC/C) is the u

285 Control of mitotic cell cycles by the anaphase-promoting complex or cyclosome (APC/C) ubiquiti

286 The anaphase-promoting complex or cyclosome (APC/C), a multi

287 ed kinetochores during mitosis, inhibits the anaphase-promoting complex or cyclosome (APC/C), and del

288 single unattached kinetochore, inhibits the anaphase-promoting complex or cyclosome (APC/C), and pre

289 role for a master cell-cycle regulator, the anaphase-promoting complex or cyclosome (APC/C), in the

290 ochores during prometaphase and inhibits the anaphase-promoting complex or cyclosome (APC/C), thus en

291 ed kinetochores and inhibits the Cdc20-bound anaphase-promoting complex or cyclosome (APC/C), to dela

292 have been depleted of known subunits of the anaphase-promoting complex or cyclosome (APC/C).

293 R1-Bub3, Mad2, and Cdc20, which inhibits the anaphase-promoting complex or cyclosome bound to Cdc20 (

294 and destabilization of Skp2 mediated by the anaphase-promoting complex or cyclosome bound to Cdh1 (A

295 ts the "wait anaphase" signal to inhibit the anaphase-promoting complex or cyclosome until all chromo

296 The anaphase-promoting complex, or cyclosome (APC/C), is a u

297 strate recognition adaptor components of the anaphase-promoting complex) resulted in stabilization of

298 oach by isolating the complexes for the rice ANAPHASE PROMOTING COMPLEX SUBUNIT 10 (APC10) and CYCLIN

299 0(HER4) is ubiquitinated and degraded by the anaphase-promoting complex, suggesting that HER4 ubiquit

300 romiscuous E3 ligase inhibitor targeting the anaphase-promoting complex, which increases cell mitogen