ライフサイエンスコーパス: anchor cell

1 tes in a pattern centered around the gonadal anchor cell.

2 the uterine-vulval interface, fuses with the anchor cell.

3 ription of lin-3 in the vulva but not in the anchor cell.

4 un kinase (JNK) was also much more robust in anchored cells.

5 tides were required for maximal apoptosis of anchored cells.

6 Data for anchor cell ablation fix the parameters needed to define

7 Replacement regulation upon anchor cell ablation is conserved in some species, but l

8 gh coordinated signaling between the uterine anchor cell (AC) and a ventral uterine (VU) cell.

9 granddaughters attach to the somatic gonadal anchor cell (AC) and generate four vulF cells, while the

10 ment, LIN-12 (Notch) signaling specifies the anchor cell (AC) and ventral uterine precursor cell (VU)

11 During C. elegans vulval development, the anchor cell (AC) in the somatic gonad expresses lin-3, a

12 A cell fate decision in which the anchor cell (AC) induces adjacent ventral uterine interm

13 The uterine anchor cell (AC) induces the vulva through LIN-3/epiderm

14 Using the model of anchor cell (AC) invasion in C. elegans, we have previou

15 genetically and visually accessible model of anchor cell (AC) invasion in C. elegans, we have recentl

16 through their juxtaposed BMs at the site of anchor cell (AC) invasion in C. elegans.

17 sing an RNAi screen and live-cell imaging of anchor cell (AC) invasion in Caenorhabditis elegans, we

18 veloping live-cell imaging methods to follow anchor cell (AC) invasion in Caenorhabditis elegans, we

19 C. elegans anchor cell (AC) invasion is a genetically tractable in

20 as a precisely regulated requirement of the anchor cell (AC) invasion program.

21 eening for defects in Caenorhabditis elegans anchor cell (AC) invasion, we found that UNC-6(netrin)/U

22 The presence of the anchor cell (AC) nucleus within the utse is necessary fo

23 in directing development and function of the anchor cell (AC) of the gonad, the critical organizer of

24 fusion of the Caenorhabditis elegans uterine anchor cell (AC) with the uterine-seam cell (utse) is an

25 ell in the Caenorhabditis elegans gonad, the anchor cell (AC), initiates uterine-vulval contact throu

26 ion, the daughters of the VPC closest to the anchor cell (AC), P6.p, are induced by the AC.

27 naling activity of a gonadal cell called the anchor cell (AC).

28 3 promote expression in vulval cells and the anchor cell (AC).

29 al lineages and in the LIN-12/Notch-mediated anchor cell (AC)/ventral uterine precursor cell (VU) dec

30 During the naturally variable anchor cell (AC)/ventral uterine precursor cell (VU) dec

31 egans hermaphrodite vulva, a signal from the anchor cell activates the LET-23 epidermal growth factor

32 A single cell, the anchor cell, acts to induce and to organize specializati

33 in-1 (TAG-1), a glycosylphosphatidylinositol-anchored cell adhesion molecule.

34 TN3-6), a group of glycophosphatidylinositol-anchored cell adhesion molecules involved in the wiring

35 IgLONs are a family of four GPI-anchored cell adhesion molecules that regulate neurite o

36 ontaining glycosylphosphatidylinositol (GPI)-anchored cell adhesion molecules, as a candidate TSG in

37 Suppression of ZmHb2 induces PCD in the anchoring cells, allowing the embryos to develop further

38 s abnormal, the utse failed to fuse with the anchor cell and a functional uterine-vulval connection w

39 fos-1 is expressed in the anchor cell and controls invasion cell autonomously.

40 around the same time by an induction by the anchor cell and lateral signaling between the vulva prec

41 ne lin-11 expression responds to the uterine anchor cell and the lin-12-encoded receptor.

42 t utse development: the uterine toroids, the anchor cell and the sex myoblasts.

43 fects in the generation of distal tip cells, anchor cells, and spermatheca; three of the five tissues

44 sequent induction of the pi cell fate by the anchor cell are mediated by the lin-12 gene.

45 Two types of mutants with defective anchor cell behavior reveal that anchor cell invasion of

46 In cog-2 mutants, the anchor cell does not fuse to the uterine seam cell and,

47 Both the initial selection of a single anchor cell during the anchor cell vs. ventral uterine p

48 In fos-1 mutants, the gonadal anchor cell extends cellular processes normally toward v

49 ventral uterine pi-cell differentiation and anchor cell fusion.

50 h pre-exposed and non-exposed to agents; non-anchored cell-gels were then incubated with agents for v

51 In wild-type animals, the somatic gonadal anchor cell generates the LIN-3/EGF ligand to induce vul

52 After the anchor cell has induced specialized uterine intermediate

53 After the anchor cell has induced the vulva, it stretches toward t

54 The cell fates of the anchor cell in hermaphrodites and the linker cells in th

55 rane cation-dependent heterodimers that both anchor cells in position and transduce signals into and

56 sup-17 activity causes the production of two anchor cells in the hermaphrodite gonad, instead of one-

57 Expansion of purged GPI-anchor+ cells in the Mut lines and analyses using aeroly

58 Our work supports a model in which AdamTS-A anchors cells in place and preserves CNS architecture by

59 ditis elegans hermaphrodite development, the anchor cell induces the vulva and the uterine pi cells w

60 The anchor cell induces the vulva from ventral epithelial ce

61 imaging of the DCC orthologue UNC-40 during anchor cell invasion in Caenorhabditis elegans, we have

62 h defective anchor cell behavior reveal that anchor cell invasion of the vulva is important for formi

63 multichannel time-lapse confocal imaging of anchor-cell invasion in live Caenorhabditis elegans.

64 , we genetically dissect this process during anchor-cell invasion into the vulval epithelium in C. el

65 ypeptide growth factor activation of MAPK in anchored cells is far more effective than in cells maint

66 or cell invasion, the Caenorhabditis elegans anchor cell migrates through basement membranes towards

67 nvade past basement membrane, the C. elegans anchor cell must cease dividing before differentiating a

68 ection between the vulva and the uterus, the anchor cell must fuse with the multinucleate uterine sea

69 to respond to the inductive signal from the anchor cell of the somatic gonad.

70 signated positions and directly transfer the anchored cells onto various substrates.

71 vulval precursor cells further away from the anchor cell (P3.p, P4.p, and P8.p).

72 in the vulval precursor cell closest to the anchor cell (P6.p) prevents induction of vulval precurso

73 The anchor cell plays a central role in organizing the repro

74 A new study reveals that the anchor cell polarity network can break symmetry and osci

75 In C. elegans, the anchor cell signal induces Pn.p cells to form the vulva

76 that mpk-1 may transduce most or all of the anchor cell signal.

77 LIN-39 activity is also regulated by the anchor cell signal/let-23 receptor tyrosine kinase/let-6

78 (encodes an Ets transcription factor) in the anchor cell signaling pathway.

79 In the different monodelphic species, anchor cell specification is biased, or fully fixed, to

80 family of glycosylphosphatidylinositol (GPI)-anchored cell surface antigens.

81 family of glycosylphosphatidylinositol (GPI)-anchored cell surface antigens.

82 e and a glycosylphosphatidylinositol- (GPI-) anchored cell surface coreceptor, either GDNF family rec

83 pression of ART2.1, but not ART2.2, as a GPI-anchored cell surface ectoenzyme.

84 se (ADPRT) is a glycosylphosphatidylinositol-anchored cell surface enzyme on CTL.

85 eport that the glycosyl phosphatidylinositol-anchored cell surface glycoprotein T-cadherin (encoded b

86 are a family of glycosylphosphatidylinositol-anchored cell surface heparan sulfate proteoglycans impl

87 llular matrix ligand (laminin) or a membrane-anchored cell surface ligand (ADAM 2).

88 bsence of glycosylphosphatidylinositol (GPI)-anchored cell surface membrane proteins in affected hema

89 ow that the folate-receptor 1 (FolR1), a GPI-anchored cell surface molecule, specifically marks mesDA

90 The mechanism by which membrane-anchored cell surface proteases utilize these putative a

91 ndings are likely relevant to other membrane-anchored cell surface proteases.

92 s use the glycosylphosphatidylinositol (GPI)-anchored cell surface protein hyaluronidase 2 (Hyal2) as

93 gen (PSCA) is a glycosylphosphatidylinositol-anchored cell surface protein that is expressed in norma

94 displayed properties of a glycophospholipid-anchored cell surface protein.

95 encode putative glycosylphosphatidylinositol-anchored cell surface proteins of the opportunistic fung

96 Here we describe a family of GPI-anchored cell surface proteins that function as ligands

97 ily members are cysteine-rich, generally GPI-anchored cell surface proteins, which have definite or p

98 , glycosylphosphatidylinositol-anchored (GPI-anchored) cell surface glycoprotein.

99 PSCA is a glycosylphosphatidylinositol-anchored cell-surface protein belonging to the Ly-6/Thy-

100 YAL2) encodes a glycosylphosphatidylinositol-anchored cell-surface protein that serves as an entry re

101 Second, the glycosylphosphatidylinositol-anchored cell-surface protein Thy-1 significantly partit

102 ctually a glycosylphosphatidylinositol (GPI)-anchored cell-surface protein.

103 emonstrate that glycosylphosphatidylinositol-anchored cell-surface receptors of the Nogo Receptor fam

104 is a family of glycosylphosphatidylinositol-anchored, cell-surface heparan sulfate proteoglycans.

105 to a family of glycosylphosphatidylinositol-anchored, cell-surface heparan sulfate proteoglycans.

106 w the DDR2-ECD, when expressed as a membrane-anchored, cell-surface protein, affects collagen fibrill

107 evelopment is initiated by a signal from the anchor cell that is transduced by a receptor tyrosine ki

108 ly protein, is first produced by the gonadal anchor cell to induce vulval precursor cells to generate

109 ferentiation within a tissue by mechanically anchoring cells to their neighbors.

110 ll differentiation that specifically affects anchor cell-uterine seam cell fusion.

111 The anchor cell/ventral uterine precursor cell (AC/VU) decis

112 f sel-5 activity can suppress defects in the anchor cell/ventral uterine precursor cell fate decision

113 selection of a single anchor cell during the anchor cell vs. ventral uterine precursor cell decision

114 Escherichia coli Spr is a membrane-anchored cell wall hydrolase.

115 ration in bacteria can be driven by membrane-anchored cell wall hydrolases.

116 Glycosylphosphatidylinositol (GPI)-anchored cell wall proteins play an important role in th

117 the class of yeast serine/threonine-rich GPI-anchored cell wall proteins.

118 and release of glycosylphosphatidylinositol-anchored cell wall proteins.

119 the class of yeast serine/threonine-rich GPI-anchored cell wall proteins.

120 This study demonstrates that sortase-anchored cell wall-associated proteins are responsible f

121 molecules, glycerophosphoinositide membrane anchors, cell wall pectic noncellulosic polysaccharides,

122 aa renders them equally likely to become the anchor cell, which links the uterus to the vulva.